Name: MCAS, COVID & Cancer: Advanced Genetics Part 2 | DrTalks
Uploaded: 2022-09-15T13:00:47-07:00
Description: Part 2: Advanced Genetics And Pathways Involved In MCAS, COVID, And Cancer

Aluminum

Antiperspirants

Anxiety

Bh4 Levels

Bleeding Time

Breast Cancer

Cancer

Carnahan Reaction

Catalase

MCAS, COVID & Cancer: Advanced Genetics Part 2

Reversing Mast Cell Activation and Histamine Intolerance Summit 2022

<h6>Bob Miller, CTN</h6>
endothelial nitric oxide, and we have a substance called BH4, combined with oxygen, something called NADPH, and L-arginine to make nitric oxide. eNOS enzyme does that. And it's also NADPH-dependent. This is what won the Nobel Prize in 1998 for circulation support from nitric oxide. However, here's your eNOS enzyme. I'm sorry, your iNOS enzyme or NOS2, when we're faced with bacteria, virus, fungus, or parasites, kicks in, makes a lot of nitric oxide to kill the pathogen. Good thing? Of course, unless it's excessive. Tissue damage, organ dysfunction. Now, there's also something called NOS uncoupling. BH4, tetrahydrobiopterin it's a biopterin and four hydrogens, donates to make the nitric oxide. If this guy's running too fast and too long, we run out of BH4. Now, when BH4 does its job, it turns into BH2, two hydrogens. Quite simply it has to be recycled. But there are genetic mutations QDPR, not enough NADPH. And we're not gonna get into it today, but there's two pathways that we make BH4. And we can actually have mutations along these paths here. It actually comes from the citric acid cycle. And then we need methyl folate, and we can have genetic mutations along here that we don't make enough BH4. When we don't have enough BH4, rather than making nitric oxide, we make superoxide free radical. Bad guy, combines with nitric oxide, makes something worse called peroxynitrite, further suppresses your BH4. And here is another pathway that feeds upon itself. Now, I've been talking about this for a while. It's only in the last couple of months that we realized that histamine is one of the things that pushes this from the mast cells.

https://d1tnc8rqovg0h0.cloudfront.net/2022+Summits/Mast+Cell+Summit/Transcripts/Mast+Cell+Summit+2022-+Bob+Miller%2C+CTN+Part+2+Transcript+File.pdf

Bob Miller is a Traditional Naturopath specializing in the field of genetic-specific nutrition. He earned his traditional naturopathic degree from Trinity School of Natural Health and is board certified through the ANMA. In 1993, he opened the Tree of Life practice and he has served as a traditional naturopath for 27 years. For the past several years, he has been engaged exclusively with functional nutritional genetic variants and related research, specializing in nutritional support for those with chronic Lyme disease.

Bob Miller, CTN

Beth O’Hara is a Functional Naturopath, specializing in complex, chronic cases of Mast Cell Activation Syndrome, Histamine Intolerance, and Mold Toxicity. She is the founder and owner of Mast Cell 360, a Functional Naturopathy Practice designed to look at all factors surrounding health conditions – genetic, epigenetic, biochemical, physiological, environmental, and emotional.

MCAS, COVID & Cancer: Advanced Genetics Part 2

Beth O’Hara, FN

Bob Miller, CTN

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Beth O’Hara, FN