Brain Damage: Infections And Toxins And You, Oh My!

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Summary
  • Overview of one of the main causes of mental health and brain dysfunction called “encephalopathy”
  • Review of how infections and toxins can cause encephalopathy
  • How parasites, viruses, and bacteria can cause systemic inflammation and lead to a damaged blood brain barrier (BBB)
  • Neuroinflammation and microglial activation as part of the picture for infections affecting the brain
  • How the immune system can attack the brain and damage important structures involved with mood and behavior regulation
  • Broader context of non-infection causes for brain and mood imbalances
  • Lab testing to identify triggers for encephalopathy
Transcript
Dr. Miles Nichols

Hello everyone and welcome to the Microbes and Mental Health Summit. I’m your host Dr. Miles Nichols. Today to talk to you about brain damage and no I’m not talking about taxes or a problem child, all the latter problem child actually may be caused by these same issues. I’m talking about infections and toxins and you. Oh my because infections and toxins can actually cause either neuro inflammation that can damage the brain and or can initiate an auto antibody attack against your own brain tissue meaning you your own immune system attacking itself. That’s the you. So we’re talking here about a post-infectious brain autoimmunity and the research that supports infections as a cause for health, mental health and brain imbalances. And there’s research that support the link between infections in brain alterations. This research study infectious disease associated encephalopathies in self allot of who encephalopathy is an umbrella term for brain dysfunction. Either structural and or functional issues with the brain. So it includes a lot of different things and we’re focusing in on the infectious triggered encephalopathy. Today the structural the functional insult to the brain. In some of the other talks I’ve talked about other ways in which brain can be damaged but this really infections toxins we see can contribute to systemic inflammation that can contribute to issues with the blood brain barrier. Just like you have an intestinal barrier that is supposed to prevent toxins and bacterian things from getting through the gut lining and it’s supposed to just transport these proteins, these protein transporters taking your nutrients, your immuno acids in. 

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