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Dr. Stephen Sideroff is an internationally recognized psychologist, executive and medical consultant and expert in resilience, optimal performance, addiction, neurofeedback, leadership, and mental health. He has published pioneering research in these fields. He is a professor at UCLA in the Department of Psychiatry & Biobehavioral Sciences and the Department of... Read More
Recently named by Fortune as one of the “World’s 50 Greatest Leaders,” Peter Diamandis is the Founder and Executive Chairman of the XPRIZE Foundation, which leads the world in designing and operating large-scale incentive competitions. He is also the Executive Founder of Singularity University. As an entrepreneur, Diamandis has started over 25... Read More
- The longevity mindset
- The use of technology in promoting longevity
- The basics are still most important
Related Topics
Aging, Diet, Epigenetic Control, Exercise, Gene Therapy, Inflammation, Longevity, Mindset, Sleep, Stem Cell RestorationDr. Stephen Sideroff
Welcome to another episode of reverse Inflammaging Summit Body and Mind Longevity Medicine. And I’m very pleased during this particular session to invite Peter Diamandis to join us. Peter has been recently named as one of Fortune’s 50th 50 greatest leaders. He’s the founder and executive chairman of the X Prize Foundation, executive founder of Singularity University, and he’s the author of four New York Times best selling books, including the most recent One Life Force with Tony Robbins. Peter. It’s such a pleasure to welcome you to our program.
Peter Diamandis, MD
Pleasure, Steve. Good to be here.
Dr. Stephen Sideroff
Let’s start by just kind of giving us a sense. I know that there’s so many different areas that cutting edge areas that you’re involved in. But how did you get interested in the area of longevity?
Peter Diamandis, MD
You know. I grew up in a medical family. My father was an O B G Y N. My mom should have been a doctor around his office and it was expected to become a doctor. I went to M I T undergrad for molecular genetics. And in the night time I would do focus on everything related to space. I was a space junkie star Trek and Apollo really lit me on fire. Ended up going to medical school, did a joint program at M I T and Harvard. And after I got my diploma, I shipped a photocopy to my parents and then went and started focusing on my space journeys and started building companies in the space arena launch and satellite and zero gravity company Space University and, and pursued space for 30 years. And it was about 20 years ago that I really started getting, focusing in on exponential technologies, how computation, sensors, networks AI, robotics and everything going on in biotech had the potential to reinvent every industry and in particular, um it hit me that lifespan health span was a huge opportunity for disruption. And it came, my interest in this area came from two different places. One from my childhood desire to open up space. I, you know, there was not, there’s not been enough progress to make me happy, right? We haven’t seen the Star Trek, we haven’t been on back to the moon or gone to Mars. So I figured, OK, I need an extra 50 years on this planet to at least see the potential of what I desire to see. The second is just the grand challenge of it all. And I think there’s no greater gift you can give than increased health span and no bigger business on the planet. You know, for me, I have, I have a half a billion dollar venture fund called Bold Capital. And we had been investing mostly in exponential tech and robotics and AI.
But I’ve shifted the fund mostly two thirds now to biotech with a age, you know, and longevity focus because I think it’s the one of the biggest markets out there. So, in those areas, there was one pivotal moment for me, Steve when I was in medical school. I watched this television show on long lived sea life and it was talking about how bowhead whales could live 200 years and Greenland sharks could live four or 500 years. And I remember thinking, if they can live that long, why can’t we? And I said it’s either a hardware problem or a software problem. And I think this is the decade where we start to make a dent in those problems.
Dr. Stephen Sideroff
Yeah. So it’s a convergence of a lot of very important facts there, including your own interest in having more time here to do all of these exciting things.
Peter Diamandis, MD
Yeah, it’s the most exciting, exciting time to be alive. So I want to see as much of it as I can.
Dr. Stephen Sideroff
Right. Right. Can you give us your perspective on aging? Like why we age? I know you mentioned hardware software. But what’s your perspective on why we age?
Peter Diamandis, MD
Yeah, that’s a great question. And I think of it, the following, right? And these are the fundamental sort of baseline facts that get me thinking about aging in this way. It’s, you know, we’re all born with 3.2 billion letters from our father and our mother and we have the same genome really throughout our lives at birth at 20, at 50, at 80, at 100. So why do you look different? Why do you age? Right. It’s not the genes you have. It’s which genes are on and which genes are off. Obviously, David Sinclair is a friend and his theory on you know, the information theory of aging for me holds a lot of validity. But it’s again, it’s the notion of making sure that your epigenetic control of your body of your, of your genome is, is solid. And it’s, You know, the other thing that hits me is that when we were evolving on the savannahs of Africa 100,000 years ago, you know, during the time we call cavemen, you go into puberty at age 12 or 13. By the time you were 24, 25, 26, you were a grandparent, your babies were having babies. And back then before we had an abundance of food before McDonald’s and whole foods was around. If nature’s mission was to perpetuate our species to pass on our genome generation to generation. The last thing you wanted to do was steal food from your grandchildren’s mouth. So there was a, a positive bias for an early end of life, there was no selective factors to keep you alive longer. And so we evolved in that direction.
Now, the question is, can we go from Darwinism evolution by natural selection to, you know, an evolution by intelligent direction? Can we reinvent the software and hardware of our body? Can we understand the fundamentals? And along these lines, this is where you know the work that I do in studying exponential technologies really flips my mindset. The realization is we all inherently have a linear bias in how we think we expect tomorrow and next year to be very much like this year, a little bit of progression, maybe not too much. But the fact is, and I think this is the work that my colleague and mentor Ray Kurzweil has has spoken about we’re gonna see in the next decade as much progress as we’ve seen in the past century, that’s how fast technology is accelerating. And so I think that we’re gonna see a disproportionate application of artificial intelligence. And what’s coming just after that, that’s going to make AI look like it’s standing still, which is quantum technologies, quantum computation sensors and communications enable an understanding of biology which I think at its basis, you know, molecular in nature is quantum in nature. We’re gonna start to understand fundamentals there.
And I think we’re going to start adding additional healthy years onto our life. And that brings about what Ray and Aubrey De Gray have spoken about as longevity, escape velocity. The notion that there’s going to be a moment in time that for every year that you’re alive, science is adding more than a year to your life. I had interviewed Ray and George Church for my book that I did with Tony, Life Force. And I asked Ray, when do you think we’re gonna reach longevity escape velocity? And now Ray is not a biologist, but he is a technologist and has one of the most accurate predictions out there. If you Google his name and predictions, it’s like 84% accuracy. And his prediction on when we reach longevity escape velocity is the next 10 to 12 years. I, when I asked George, I expected him to be a lot more conservative and he was, but not by much, you know, it’s like 15 to 20 years. So our job here isn’t to live an extra 50 years. It’s to live long enough to intercept the new technologies coming in the next 10 to 20 years.
Dr. Stephen Sideroff
Right. Right. Well, that’s, we’re very close then based on both of their predictions. Yeah. There are a couple of directions I’d like to go with just the first response that you gave me. But one of the things that I know, is very important in your perspective. Is mindset. I wrote an article recently on purpose, which I did. I said it is the ultimate and use it and lo or lose it. And you talk about mindset as being very important. How does mindset impact longevity in your opinion? And what would be the mechanism that happens in that process?
Peter Diamandis, MD
Sure. So, there’s a quote I use from my dear friend Dan Sullivan. He goes need to make sure that your future is bigger than your past, right? And that’s a very simple but very big idea that if you’re, if you feel like, listen, I’ve lived my life, there’s nothing more to look forward to, it’s done. You know, if you look at the research, you can effectively will yourself to death. And we all know situations where, you know, one spouse dies and then a few days later or a few weeks later, the second spouse dies, you know, and that was not predetermined at birth. It was an impact of losing someone that’s that close to you.
So there is a physiological connection between mind and body. There’s also a connection of, you know, if you’re excited about life, if you’re vibrant, you know, keeping your mind engaged and your body engaged, all of these things have secondary and tertiary benefits. One of my favorite stories has to do with the founding fathers of our country. I’m trying to remember which two founding fathers it was, I think it was Benjamin Franklin. And, I’m, I’m blanking on the second. Who, they both lived exactly to the 50th anniversary of 1776, July four, and died on that day. They lived to see the 50th anniversary of the nation that they had started. And again, is that random? I don’t think so. I think it’s like having something to look forward to that keeps you alive.
So I think mindset is very important. I think of, you know, today before we have epigenetic reprogramming and gene therapies and stem cell, you know, restoration and all the like of medicines out there before we have the basics for extending the healthy lifespan, right? It’s diet, exercise, sleep mindset and not dying from something stupid, which I can talk about in a second. But in the mindset, you have to believe that in fact, there are breakthroughs coming that the technologies to extend your lifespan are on the horizon that you have something to look forward to. So that you have less inflammation, less aches and pains, less, you know, low energy days. And one of the things I did, Steve was I built an AI called Future Scope that searches the world’s information for news on any subjects, vets the information for high scientific validity and then creates a summary of the article with an appropriate image. So I set it free and, and, and built something called longevity insider dot org. So every day I get the top 10 breakthroughs in the field of longevity. And I read and it’s like, oh my God, that’s amazing. I had no idea because, you know, we never see this in the news media today unless you’re actively looking for it. So longevity insider dot org is free for me. It’s how I maintain my longevity mindset because I’m seeing every day the progress being made on all of these technology fronts.
Dr. Stephen Sideroff
I can think of two different ways that mindset may play a role here. One is that it sends some kind of direct message to our genome that actually makes some changes there. And the other is simply that with a positive, healthy mindset, the body functions more efficiently, more effectively and therefore it ages more slowly. Do you see those as two separate processes or the same?
Peter Diamandis, MD
You know, I won’t venture to guess, but I also think there’s a third process which is if you’re excited about what you’re doing, you’re gonna get out of bed earlier, you’re gonna get, you’re gonna want to feel better, you’re gonna learn. Of course, we all know that you know, brain plasticity is a real thing. What you do when you learn, when you and Robert put on this event and you’re engaging and you’re learning and you’re talking, that is really driving you forward instead of waking up in the morning and deciding whether you’re gonna make a cup of coffee or not. So, I mean, there is you know, one of the challenges is this four letter word, spelled retirement. You know, it’s people retire and lose their will to do anything. And I think retirement is a bad idea for anybody. There’s a correlation between when you retire and when you, you know, pass away. I think it’s retirement is the equivalent mentally of telling the universe. OK. I’m done making use of my body. It’s time to give it back to the ecosystem.
Dr. Stephen Sideroff
Right. Right. And yes, and I would agree that a positive mindset does drive healthier behaviors. So, I would certainly agree with that back to your analogy to the cave man and 100,000 years ago and how we lived into just our twenties or, or thirties. And we have the evolutionary sort of baggage or legacy of that in terms of many of our enzymes, hormones beginning to drop off around that age.
Peter Diamandis, MD
Yes. Exactly.
Dr. Stephen Sideroff
What’s your feeling about replacement therapies to replace those decreasing substances.
Peter Diamandis, MD
Yeah. I think that it is important to try and get us to homeostasis again, get us back to baseline. So I do testosterone supplementation. I use a peptide to boost my I G F one levels. And a variety of things and I won’t go into a list of them here. But, you know, I’ve had the chance to start two companies. One called Fountain Life that we can talk about. That really is a diagnostic side of the equation, a therapeutic side of the equation. On the therapeutic side, it really is about how do we bring you back to, you know, hormone optimization versus just supplementation.
Where should you be? And then another company I started with Tony Robbins, called Life force. That is similarly with peptides, medicines, hormones, really trying to get you back to a baseline. So do I believe that it’s that we need to supplement what we have? Absolutely. I’m also a big believer in the power to restore our stem cell populations, our regenerative engine of our body, right? It’s not legal in the United States other than your own stem cells from fat or bone marrow. But the research will get done. One of the companies I co-founded with Bob Huy who’s the chairman, Ceo of Cellularity. I serve as the co-founder and vice chairman is the largest facility placental facility out there. We have stored hundreds of thousands of placentas, we decell uar those to bring out the natural killer cells, the T cells, the stem cells and the excess that are then really developed as cellular medicines to address everything from immune function to sarcopenia, to wound healing. To really the natural killer cells being used to fight a number of different cancers and clinical trials. Today.
Dr. Stephen Sideroff
You mentioned in that comment exosoes. What’s your opinion on their value in terms of longevity?
Peter Diamandis, MD
So I think exo again are in the gray zone from the perspective of the FDA today. I think that we need to give those companies support to produce those because I think they are, there is value for them. I have used exomes myself in terms of accelerating wound healing, postsurgical. And I think that this is really, it’s giving your body the growth signals and repair signals that it might have done in your twenties. But in your fifties, sixties, seventies no longer has the capability to provide. So a lot of research still to be done. A lot of work under I RBS and I N DS. But I think these are incredibly important tools. There’s a company, I’m an advisor and an investor to called immunes that has been really is in human clinical trials right now. Pulling, you know, CRE taking the exudate of stem cells, really all of the growth factors and the exo umes and using that as a mechanism to stimulate and maintain muscle mass. And we, I think most everybody here will know muscle mass is one of the critical factors for longevity. There’s a direct correlation between your muscle mass. And so I’m, you know, I’m fighting Sarcopenia every day. I’m 61 and I work out, I’ve increased my protein intake to handle it. But I would love any other technologies that allow me to maintain a significant level of muscle.
Dr. Stephen Sideroff
So these approaches that you’re just describing, including stem cells, et cetera. What’s the time frame in terms of when they are, might, might be fully available?
Peter Diamandis, MD
So they are available outside the United States today. So we don’t at Fountain Life on the therapeutic side, we don’t have, we don’t provide stem cells domestically today. We send people, we’ve vetted six or seven different stem cell clinics outside the US and the Caribbean and Mexico, Panama, Costa Rica, other locations. And we’ve sent our members to the Regenerative Medicine Institute in Costa Rica. Doctor Vince Gim Papa there. Just because the level of service and the science there, we think is, is very high.
We’ve been looking with cellularity to implement an I N D to look at placental stem cells. So we’re gonna see this over the next, you know, increasing in capability, but under really critically vetted scientific measures and data collection, right? We need to collect the data to a dent to make sure that it is safe and efficacious under what conditions it is. So, I think that’s this decade. But stem cell exhaustion is definitively one of the hallmarks of aging, right? I mean, if you look at stem cell populations and a newborn, compare it to someone in my age, you know, in your, in every different segment of tissues, we’ve seen stem cell reduction by a factor of 100 to 1000 fold. And that’s challenging and, and challenging in your ability to repair and challenging in your ability to maintain functionality and vitality of those tissues and organs.
Dr. Stephen Sideroff
Yeah. Yeah. And so like back to some of these supplements, for example, N AD, which is so important to the health of our mitochondria. What’s your opinion in terms of when you take these supplements? Do you, do you believe they’re actually going to where they have an impact?
Peter Diamandis, MD
So N ad obviously is, is not a supplement, it is the powerhouse inside the cell, right? The precursor, you know, there’s no carrier molecule for N AD to get it across the cell membrane that we know right now. And the precursors are N M N and, and N R. And I do take about a gram of N M N every day. Is it, do I feel a physiological difference from that? Maybe. But I think it’s more based on belief than anything else. And there is good science data in animal studies today, not human studies. There is a study going on right now by a company called Metro Biotech run by a friend of mine which is doing a study with the US special forces.
And they have a very purified form of N M N called MI-6 M I B 626 that they’re looking at. And they’re providing under a clinical study under a double blind study with special forces looking at increased muscle strength and cognitive capability. And the early study results were very positive and we’ll see where that plays out over the next few years. So, am I excited? Yes. Do I think we really hit the knee of the curve yet? No, I think we’re gonna see a massive data set being analyzed by AI in the next 1 to 4 years. And then quantum technology is really making a huge dent in this, in the next 4 to 6 years. Hm. It’s quite something else for us to look forward to. It is and I think having something to look forward to is part of that mindset element.
Dr. Stephen Sideroff
Yeah. I, yeah. Yeah. And so what other mechanisms do you think are out there in terms of our ability to slow or reverse epigenetic aging?
Peter Diamandis, MD
Well, there’s, there’s one thing which is important and you may have someone from Fountain Life speaking as well. It’s a company I serve as executive chairman of and co-founded with, with Tony Robbins and, and Mark Benioff. And Fountain Life has built these 10,000 square foot diagnostic centers where we do full body MRI brain, brain imaging, brain vasculature and AICoronary C T Dexa scan genomics, 150 gigabits of data. And the reality is we are always in a state of some level of degradation degeneration.
As you said, you know, after 30 it’s, you know, our thymus start shrinking, our hormonal levels, start going down, our growth hormone levels start going down. And so we’re in a slow decline. And The other thing going on is that we start to develop diseases that were never preselected against because you had reproduced by the age of 30. And so these diseases would occur later on in life and we’re all developing cancers all the time. Hopefully, our innate immune system, our natural killer cells are finding those cancers and zapping them. But there’s another thing called immune exhaustion as we get viral burdens in our body, our N K cells are focused on viruses and not cancers. And that’s a challenge. So, one of the things that we do at found life is we do an annual upload where you’re fully digitized and then quarterly additional testing. And the goal is to find disease at inception. And zap it at the beginning, our bodies are incredibly good at hiding problems. You know, you don’t feel a cancer at stage one or stage two, you experience at stage three or stage four many times when it’s too late, right? For Parkinson’s, you don’t really have the tremor until like 70% of the neurons are gone and your body compensates for all these things and unless you’re looking, you do not know. So in our first, I think like four or 5000 patients going through all this testing, our members going through this testing, We’ve discovered 2% have a cancer, they don’t know about 2.5% have an aneurysm.
They don’t know about 14.4% have a significant finding that is could impact their lifespan that they need to know about. And so I call this category you know, not dying from something stupid. In other words, looking and understanding and then when you find something, taking action right away, you know, in like in the wildfire world, do you want to try and put out the wildfire after it’s a conflagration or at the first spark, right? And it’s the same thing here. You know, you’re gonna find out eventually. When do you want to know the beginning or later? So that’s what we built with Fountain Life. We also built an insurance company called Fountain Health Insurance, which I’m very proud of where for your current health insurance for self-insured company? At 1000 bucks a month, we give your employees all of the testing for free. So the health insurance instead of paying you after you’re sick and have had your surgery. The goal of the health insurance is to keep you from getting sick in the first place. So, again, there are lots of things that can be done in that regard.
Dr. Stephen Sideroff
You know, I think it’s so important to get baseline, baseline measures and then as you continue to take measures, perhaps every year, it’s not only looking at you compared to the normal, it’s also you compared to where you were a year ago so that you actually pick up on changes that may not be appropriate.
Peter Diamandis, MD
Exactly. The first time I did a full body MRI I discovered I had an enlarged aortic root and it was like, is that me or is there something going on? And it hasn’t changed in eight years. And so it’s my baseline, which is good to know, right. And so understanding your baseline, like you said, Steve is, is super critical.
Dr. Stephen Sideroff
Yeah. Yeah. So in terms of when we think about repair, cellular repair, a more and more popular approach now is intermittent fasting, fasting, mimicking diets. And I’ve heard people talk about, well, you have to do, you have to fast for two days, 48 hours before that repair process takes place. Others say no, it’s more or less on a continuum that you can, you can trigger the process after 14, 12, 14, 16 hours. What’s your perspective on that?
Peter Diamandis, MD
So, listen, the, the work done by Victor Longo at U C L AIthink is pretty definitive and has been vetted by multiple studies. You know, the, the fasting mimicking diet. I actually just did it at this on January 2nd through sixth, right to start off the year. And it’s a five day diet. The first day is 1200 calories. The second through fifth day is 800 calories. And it’s the prolong diet is what it, what it is and it, I found it very easy to do. According to them, that diet is better than just a water diet. Meaning the impact on your physiology and knocking out your senile cells and, and getting in stimulating auto is, is higher than if you did nothing. So, I found it sufficient enough that I’m, I’m gonna probably do it once a quarter. Atleast twice a year, but I hope for once a quarter.
The second thing I’ve just started doing in my abundance 3 60 Community Steve at the beginning of the year and we, I just did these back to back. We do a 22 day no sugar challenge. And if there is one recommendation on diet over fasting over in fasting over plants over anything, it’s eliminating sugar. I think, you know, glycated of proteins of cholesterol is a root cause for much cardiovascular and neurological disease. And so I’m wearing my CGM, I’ve got my levels patch on my arm over here and let’s see what my level is here right now. Let’s see. OK, I’m at 90 90 mg per deciliter. And so I, you know, I look to make sure I have zero spikes during the day. And trying to get my, you know, my hemoglobin A one C is been at 5.3. I’m trying to get it down to five. We’ll see if I can do that.
You know, I take a gram of Metformin near as a friend. I believe the data that he has. And so, and then I’m also taking rain. The data is reasonably good. Again in animal studies, there is a rain study that has just been initiated, I believe, to look at its impact and right now it’s a lot of trial and error for people. It’s what do you feel is got enough upside and is safe enough for you? And what makes you actually feel good? I know that I feel better on a no sugar diet. Right. It’s, it’s difficult for sure. But after a few weeks, you can break the habit. It’s, it is, it’s addicting sugar is addicting. And again, going back to our hominid ancestors 100,000 years ago, they didn’t have sugar, there was no sugar cane plantations and, and you know, M and MS and Snicker Bars. I mean, it just, we never evolved for that.
Dr. Stephen Sideroff
Right. Right. Yeah. And I know that I’ve heard you say sugar is poison. It is. And you know, it’s one thing for people to know this, but it’s also addictive. So, in finding ways to eliminate it or reduce it, it’s really a challenge to habitual behaviors of ours. So it takes us back to the mindset issue because really we have to be very incentivized and intentional in really following through with a lot of what would be good for us.
Peter Diamandis, MD
It is, you have to care enough about yourself and your physiology and the mindset that I’m in is one that this, I’m investing in my future and the future of my kids, I have 2, 11 year old boys. And I’m excited about the future and I want to do everything I can to maximize my physiology and health to get there. And one other thing I’ll mention, you know, this 20 day, 22 day, no sugar fast or no sugar diet. It’s hard to do on your own. But we have a whatsapp group with 100 and 40 of my of my 360 abundance, 3 60 members and every morning people are sharing their experiences, their weight loss, their energy levels, their tricks and trades and what they’re eating and what they don’t. And doing things in community settings is much better.
Dr. Stephen Sideroff
Yeah, I would totally agree with that. In fact, community and feeling a part of community is, I think one of the keys to longevity as well and it’s been shown to be one of the key factors.
Peter Diamandis, MD
It is being loved and, and having a purpose and being in family and being close friends. All of things is very important.
Dr. Stephen Sideroff
Yeah. Yeah. I noticed another startup of yours and you know, I marvel at how many of these you were?
Peter Diamandis, MD
Number 26. Yeah.
Dr. Stephen Sideroff
Fantastic. The one I was thinking of is the vaccinate.
Peter Diamandis, MD
Oh, yes.
Dr. Stephen Sideroff
And you’ve talked about it as one of the goals, there is a vaccine to address cardiovascular disease. Can you say a little bit about that.
Peter Diamandis, MD
Absolutely. Absolutely. I’m super aware. That’s that. Yeah, super excited about it. So, vaccinating is a company that manufactures a peptide vaccine against proteins in the body. So, unlike a vaccine that trains up your immune system to attack a foreign virus this is looking at endo you know, endogenous proteins in your body and I have hyper cholemia. My dad had it and I handle my high L D O levels by taking something called repatha, which is a monoclonal antibody. And it’s a monoclonal antibody against an enzyme in the liver called P CS K nine and P CS K nine in the liver produces low density lipoproteins, which is the bad cholesterol.
And so if you block the P CS K nine enzyme, you can reduce your L D L levels and it does it very effectively. And so in a vat wherever they produce it, let’s say in New York, there’s these clones of B cells producing these antibodies and the antibodies get delivered to me in a self injecting five M L syringe and I inject myself every two weeks in my thigh and it’s great, but it’s 1000 bucks in injection. It’s expensive, right? I say five, I’m sorry, it’s 1000 bucks a month, 500 bucks in injection and it’s twice a week. So it’s inconvenient at twice a month and expensive and I can afford it. But it’s a third line defense. But if you can reduce your L D O levels, it is one of the greatest combatants against heart disease and stroke.
So a year two ago, we started an internal program to see can we develop a vaccine to stimulate your immune system to create the same antibodies produced by that vat of B cell clones? In other words, anti, can you get your immune system to generate antibodies with high specificity against the P CS K nine enzyme? And in fact, we can we just finished our studies in primates. And it was exceptional at or above anything else we’ve seen out there. And there is a very high conservation between primates and humans. So we’re now entering human trials and unlike the $12,000 a year, this and an injection, you know, 24 injections a year, this would be two injections a year every six months and cost $50, right? So, because these vaccines are very low in cost to produce. And so what we have is the ability to do preemptive vaccination of individuals against developing heart disease and stroke. And there’s evidence in lots of different societies that, you know, you can start to see cholesterol build up again. This is not just cholesterol by itself, it’s all it’s glycated cholesterol, right? Sugar sticking to the cholesterol and sticking to the side and, and generating soft plaques that can evolve and, and cause a heart attack. So, yeah, so this vaccine from vaccinate is super excited about it.
Dr. Stephen Sideroff
And again, what’s the time frame?
Peter Diamandis, MD
We’re in human trials now. I am not sure, you know, we’re in phase one for safety. And we have this vaccine platform. We have had in hundreds, probably thousands of humans for other targets. This vaccine platform has been, we have a COVID-19 booster that has outperformed everything else that is looking for in its registration trial right now. But we also have a vaccine against Alzheimer’s against a beta. We have a vaccine against C G R P for migraines and one against Parkinson’s too. So the system has been in humans and is safe. And we just need to get the efficacious data to be able to go to registration or trial for that.
Dr. Stephen Sideroff
Do you engage AIin this development process?
Peter Diamandis, MD
We are just now honestly, any vaccine has got a very simple target list, any place there’s a monoclonal antibody, we can train our system to produce those same antibodies that are manufactured outside the body as a monoclonal.
Dr. Stephen Sideroff
Well, this has been a fascinating conversation. Peter, I so appreciate it. And, you know, we’re in this field. That’s almost like the wild west where it’s so rapid and so many things happening. So, Rob and I are so, very interested in not only finding what might work but also what’s safe and, it seems like that’s also something that we should always take into consideration the safety of whatever we’re doing.
Peter Diamandis, MD
Yeah. No, for sure. I mean, I think the big, what makes me the most excited is we have in medicine been flying for the most part blind since its inception and it’s just now really with the emergence of, of sensors that we wear, that we inject that we consume that are in our environment. And then the massive power of AIuh we’re gonna see a fundamental revolution not in 10 years or five years in the next two or three years in which we’re, you know, we’re moving medicine out of the hospital, out of the doctor’s office into the home, right? I’ve got an apple watch is levels, continuous glucose minor and or ring, you know, and there will be many others and all of my data will flow to an AIthat knows what I ate for breakfast, lunch and dinner, how much I exercise knows my genetics understands my blood chemistries. And as a result of all of those things coming together is able to reach conclusions, analyzing the data that no human ever could. And so this is the magic that’s before us. And what makes it exciting to be alive right now?
Dr. Stephen Sideroff
Yeah, definitely. And just the ability to measure and monitor increases a person’s awareness which in and of itself creates change. So all of this is wonderful. You have a great website. I’ve been on it. I’ve engaged in your mindset program and others, You have a wealth of information. How can people find that information? Can you give us the website?
Peter Diamandis, MD
And yeah, if you go to just my last name, Diamandis.com, I put out two tech blogs per week. Typically on one’s on health and biotech focused ones on exponential technologies and how they’re transforming industries. There are, I have a you know, a program on finding your massive transformative purpose. And then I’m on social media. I’m just @PeterDiamandis for Twitter and Instagram. And my, I have a podcast called Moonshots and Mindsets available wherever you get your podcasts. And it’s really focused on what are the amazing moonshots that we’re taking right now. And one of the biggest ones is adding 10 2030 healthy years on your life that bridges you to get the next 10 2030 healthy years after that.
Dr. Stephen Sideroff
Well, we will look forward to all of us living that long and getting to that velocity stage where who knows what will happen next? So Peter again, thank you very much. All of your links will be in our show notes, so people will be able to reach you. So again, thank you so much.
Peter Diamandis, MD
My pleasure, Steven, take care to you and Robert. Bye now.
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I was thrilled to see Peter Diamandis, MD on this interview on the Reverse Inflammaging Summit! I’ve been following Peter for a dozen years and find him to be one of the most optimistic and insightful thought leaders around.
His journey from aspiring to extend space exploration to diving deep into the longevity sector is truly inspiring.
Diamandis’ perspective on utilizing exponential technologies to potentially disrupt and extend human healthspan is fascinating. It’s especially intriguing how he links his passion for space with the need for more time to witness humanity’s progress.
His ventures into biotech with a focus on longevity, alongside his active role in developing novel therapies and diagnostics, highlight a future where aging could be significantly managed or even reversed.
The discussion about mindset, community, and preventative health measures provides a holistic view of longevity that’s not just about technological breakthroughs but also about lifestyle choices and social engagement.
Diamandis’ work embodies the spirit of innovation with a purpose, aiming for a future where extended healthspan and lifespan are within reach. I’m a huge fan!