Can Supplemental Peptides Improve Your Gut Health?

Dr. Jenny Pfleghaar
Jen Pfleghaar, DO, ABOIM
December 9, 2023
0 reactions
1 comments
Getting your Trinity Audio player ready...

Table of Contents

What are Peptides?

What is BPC-157?

Can Peptides Like BPC-157 Heal Gut Problems?

What Peptide Brands are Known for Their Safety and Effectiveness?

New Research about Supplemental Peptides

Supplemental peptides have become a hot topic in the medical and wellness communities.

New research has been finding that peptide supplements can help protect and heal the body.

Some findings have shown that peptides can improve:

Because so many claims are made, you need to be aware of how some of these peptides are created.

High-quality brands, like Integrative Peptides, put in the research and effort needed to create effective peptides.

In this blog, you will discover what supplemental peptides can improve your gut health and how to find them.

What Are Peptides?

Peptides are the building blocks of proteins in the body. They are essentially short chains of amino acids.

Peptides are either created in the body or taken as supplements. Peptides are used by our bodies to do many different tasks. According to one article and a report from Mayo Clinic Proceedings, peptides:

  • Keep Our Hearts Healthy
  • Fight Infections and Cancer
  • Heal Wounds
  • Regulate Metabolism and Weight
  • Enhance Muscles and Exercise Performance
  • Maintain Body Heat

It is incredible how much peptides do for us, and supplemental peptides might become a first line of defense when it comes to some diseases.

Lately, research has found that one specific peptide might provide significant health benefits.

That peptide is BPC-157.

What is BPC-157?

BPC-157 stands for body protection compound (BPC) 157. BPC-157 is a supplemental peptide derived from gastric juices found in your gastrointestinal tract.

It is called a “body protection compound” because many studies have found that BPC-157 might provide our bodies with health benefits. Some of these include:

Clearly there are a lot of potential benefits of BPC-157. One potential benefit that we will discuss further is that BPC-157 may help heal gut problems.

Can Peptides Like BPC-157 Heal Gut Problems?

According to a 2023 report, one key benefit is that BPC-157 could protect and even help heal the gut and the gut-brain axis.

woman holding her gut

How Does BPC-157 Heal Gut Problems?

One study found that BPC-157 interacts with many tissues and chemicals in the body to help heal and protect.

BPC-157 might improve or heal gut problems by:

  • Repairing the Gastrointestinal Tract: one study found that BPC-157 may heal the GI tract better than many medications.
  • Reducing Inflammation: high inflammation causes poor microbiome health. Reducing inflammation allows your microbiome to recover, which leads to better overall health per one study.
  • Healing Leaky Gut: BPC-157 was reported to stabilize the cells of the GI tract and eliminate leaky gut syndrome
  • Repair NSAID Damage by Supporting the Nitric Oxide System: Nitric oxide has been found to improve gut health and heal NSAID damage.

Overall, BPC-157 has the potential to become a medical treatment for gut problems.

However, there are some brands out there that do not adequately research or test their BPC-157 products. You need to know which brands create BPC-157 that is safe and effective.

What Peptide Brands are Known for Their Safety and Effectiveness?

One key problem with supplements that are available is that they might not work. There are key features about supplement brands you need to know before making your purchase.

Some forms of BPC-157 could be ineffective.

Some companies claim that Ac-BPC-157 is not effective because it is not stable in the body, but that is not true. BPC-157 in the “Ac-BPC-157” form is active and highly-effective in the body.

According to one article, Ac-BPC-157 does not degrade in the stomach and is bioavailable.

So, what companies or brands make an effective Ac-BPC-157?

Integrative Peptides is the perfect example of a company that creates effective BPC-157. Integrative Peptides has put in the research and testing needed to develop an effective BPC-157.

Their BPC-157 products are at or above 99% purity, which cannot be claimed by many supplement companies.

Learn more about their products by visiting: https://integrativepeptides.com/chronic-gut-summit/

Videos About Peptides from DrTalks

How Peptides Saved My Life

Peptides to Maximize Your Metabolic Code

Peptides for Optimal Fitness and Athletics

Peptides to Combat Stress and Overwhelm

Summary

Supplemental peptides could provide us with many health benefits. Research on peptides like BPC-157 have found that there are potential benefits like healing leaky gut, reducing inflammation, repairing the GI tract, and more. There are many different peptides on the market, and some may be ineffective. Integrative Peptides appear to produce a safe and effective BPC-157 compound.

Disclaimer

Please consult your physician or care team if you plan to make any changes to managing your health care.

References:

Sikiric, P., Gojkovic, S., Krezic, I., Smoday, I. M., Kalogjera, L., Zizek, H., Oroz, K., Vranes, H., Vukovic, V., Labidi, M., Strbe, S., Baketic Oreskovic, L., Sever, M., Tepes, M., Knezevic, M., Barisic, I., Blagaic, V., Vlainic, J., Dobric, I., Staresinic, M., … Seiwerth, S. (2023). Stable Gastric Pentadecapeptide BPC 157 May Recover Brain-Gut Axis and Gut-Brain Axis Function. Pharmaceuticals (Basel, Switzerland), 16(5), 676. Read it here.

Czajka, A., Kania, E. M., Genovese, L., Corbo, A., Merone, G., Luci, C., & Sibilla, S. (2018). Daily oral supplementation with collagen peptides combined with vitamins and other bioactive compounds improves skin elasticity and has a beneficial effect on joint and general wellbeing. Nutrition research (New York, N.Y.), 57, 97–108. Read it here.

Vukojevic, J., Milavić, M., Perović, D., Ilić, S., Čilić, A. Z., Đuran, N., Štrbe, S., Zoričić, Z., Filipčić, I., Brečić, P., Seiverth, S., & Sikirić, P. (2022). Pentadecapeptide BPC 157 and the central nervous system. Neural regeneration research, 17(3), 482–487. Read it here.

Forbes J, Krishnamurthy K. Biochemistry, Peptide. (2022) StatPearls Publishing. Read it here.

Palmer, B. F., & Clegg, D. J. (2015). An Emerging Role of Natriuretic Peptides: Igniting the Fat Furnace to Fuel and Warm the Heart. Mayo Clinic proceedings, 90(12), 1666–1678. Read it here.

Vukojevic, J., Milavić, M., Perović, D., Ilić, S., Čilić, A. Z., Đuran, N., Štrbe, S., Zoričić, Z., Filipčić, I., Brečić, P., Seiverth, S., & Sikirić, P. (2022). Pentadecapeptide BPC 157 and the central nervous system. Neural regeneration research, 17(3), 482–487. Read it here.

Sikiric, P., Seiwerth, S., Rucman, R., Kolenc, D., Vuletic, L. B., Drmic, D., Grgic, T., Strbe, S., Zukanovic, G., Crvenkovic, D., Madzarac, G., Rukavina, I., Sucic, M., Baric, M., Starcevic, N., Krstonijevic, Z., Bencic, M. L., Filipcic, I., Rokotov, D. S., & Vlainic, J. (2016). Brain-gut Axis and Pentadecapeptide BPC 157: Theoretical and Practical Implications. Current neuropharmacology, 14(8), 857–865. Read it here.

Sikiric, P., Seiwerth, S., Rucman, R., Turkovic, B., Rokotov, D. S., Brcic, L., Sever, M., Klicek, R., Radic, B., Drmic, D., Ilic, S., Kolenc, D., Aralica, G., Safic, H., Suran, J., Rak, D., Dzidic, S., Vrcic, H., & Sebecic, B. (2013). Toxicity by NSAIDs. Counteraction by stable gastric pentadecapeptide BPC 157. Current pharmaceutical design, 19(1), 76–83. Read it here.

Sikiric, P., Seiwerth, S., Rucman, R., Turkovic, B., Rokotov, D. S., Brcic, L., Sever, M., Klicek, R., Radic, B., Drmic, D., Ilic, S., Kolenc, D., Aralica, G., Stupnisek, M., Suran, J., Barisic, I., Dzidic, S., Vrcic, H., & Sebecic, B. (2014). Stable gastric pentadecapeptide BPC 157-NO-system relation. Current pharmaceutical design, 20(7), 1126–1135. Read it here.

Skorjanec, S., Dolovski, Z., Kocman, I., Brcic, L., Blagaic Boban, A., Batelja, L., Coric, M., Sever, M., Klicek, R., Berkopic, L., Radic, B., Drmic, D., Kolenc, D., Ilic, S., Cesarec, V., Tonkic, A., Zoricic, I., Mise, S., Staresinic, M., Ivica, M., et al., & Sikiric, P. (2009). Therapy for unhealed gastrocutaneous fistulas in rats as a model for analogous healing of persistent skin wounds and persistent gastric ulcers: stable gastric pentadecapeptide BPC 157, atropine, ranitidine, and omeprazole. Digestive diseases and sciences, 54(1), 46–56. Read it here.

Lanas A. (2008). Role of nitric oxide in the gastrointestinal tract. Arthritis research & therapy, 10 Suppl 2(Suppl 2), S4. Read it here.

Sikiric, P., Skrtic, A., Gojkovic, S., Krezic, I., Zizek, H., Lovric, E., Sikiric, S., Knezevic, M., Strbe, S., Milavic, M., Kokot, A., Blagaic, A. B., & Seiwerth, S. (2022). Cytoprotective gastric pentadecapeptide BPC 157 resolves major vessel occlusion disturbances, ischemia-reperfusion injury following Pringle maneuver, and Budd-Chiari syndrome. World journal of gastroenterology, 28(1), 23–46. Read it here.

Join the discussion

or to comment
1 Comment
Oldest
Newest Most Voted
Inline Feedbacks
View all comments
Bret Gregory
Bret Gregory
4 months ago

This post about supplemental peptides, particularly BPC-157, is quite intriguing! It’s amazing to see how research is uncovering the vast potential of peptides in various health aspects like gut health, skin rejuvenation, and even central nervous system protection. The emphasis on BPC-157’s ability to heal and protect the G.I. tract and its broader implications on overall health is especially noteworthy. It’s a good reminder, though, to be cautious about the quality of supplements and to opt for reputable brands (like Integrative Peptides.) This post does a great job of explaining the complex science in an accessible way, making it easier to understand how peptides could be a game-changer in personal health and wellness. Really looking forward to seeing how this research evolves and its practical applications in everyday health management.

Daniel Chantigian
Daniel Chantigian, MS
Learn more

When it comes to complex scientific or medical topics, Daniel can successfully communicate with any audience via writing, social media, lecturing, and one-on-one discussions. Over the past decade, he developed these skills as a researcher at the University of Minnesota and the Mayo Clinic, as a lecturer at the University...

Join the discussion

or to comment
1 Comment
Oldest
Newest Most Voted
Inline Feedbacks
View all comments
Bret Gregory
Bret Gregory
4 months ago

This post about supplemental peptides, particularly BPC-157, is quite intriguing! It’s amazing to see how research is uncovering the vast potential of peptides in various health aspects like gut health, skin rejuvenation, and even central nervous system protection. The emphasis on BPC-157’s ability to heal and protect the G.I. tract and its broader implications on overall health is especially noteworthy. It’s a good reminder, though, to be cautious about the quality of supplements and to opt for reputable brands (like Integrative Peptides.) This post does a great job of explaining the complex science in an accessible way, making it easier to understand how peptides could be a game-changer in personal health and wellness. Really looking forward to seeing how this research evolves and its practical applications in everyday health management.

1
0
We would love to hear your thoughts. Join the discussion belowx
()
x
drtalks logo

SMS number

Login to DrTalks using your phone number

✓ Valid
Didn't receive the SMS code? Resend
drtalks_logo.png

Create an Account

or

Signup with email

Already have an account? Log In

DrTalks comes with great perks that guests to our site don’t have access to. Sign up for FREE

drtalks_logo

Become a member

DrTalks comes with great perks that guests to our site don’t have access to. Sign up for FREE

"*" indicates required fields

Name*
Password*

Already have an account? Log In

drtalks_logo.png

Sign-in

Login to get access to DrTalks wide selection of expert videos, your summit or video purchases.

or