Can Wegovy Protect Your Heart? Joel Kahn, MD, FACC, Provides Expert Analysis

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Joel Kahn, MD, FACC
September 19, 2023
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New Report On Novo Nordisk’s Weight Loss Drug – Wegovy

Earlier this week, Novo Nordisk announced that their weight loss drug, Wegovy, could reduce the risk of heart disease by 20%.

These results were reported from a study Novo Nordisk is performing. That study is called the “SELECT” trial. The purpose of this study is to determine how the heart is affected by the administration of semaglutide, the chemical name of the weight loss drug, Wegovy. Over 17,500 people that were overweight or obese with heart disease and no history of diabetes participated in the study.

This is the first report that semaglutide could decrease the chances of heart disease in non-diabetic patients.

Medical Expert Analysis of the Nova Nordisk Report

But what does this report really mean? We asked our medical experts at DrTalks to provide commentary on the recent health news. America’s Healthy Heart Doc, Joel Kahn, MD, FACC, provides an expert analysis of this announcement in a video posted on the DrTalks Youtube Channel.

According Dr. Kahn’s analysis, this is a promising discovery. However, there is more work needed before medical experts can accept that Wegovy will be a useful medication for heart health.

To help you understand why, Dr. Kahn said this:

“A 20% reduction is called a relative risk reduction. If 1% of the people on the placebo and 0.8% of the people on Wegovy had cardiac events. That’s a 20% drop. But it represents than less than 1 person in 100 is going to benefit from taking the expensive injection. But if it’s 10% rate of heart disease in the placebo and 8% rate of heart disease in the treated Wegovy group, then that’s an absolute reduction of 2%. And maybe it’s more than that. Maybe it went from 20% to 16%, relative reduction. And that’s a 4% absolute reduction.”

As you can see, there is still a lot of unknown information about this report. Yes, it is exciting. However, the full study needs to be published before any conclusions can be made.

In the meantime, what should you do to improve your cardiovascular health?

As Dr. Kahn says, you should keep up “with fitness programs, and with healthy diet programs like a whole food plant-based diet.”

Be sure to keep your eye on this study because there may be important findings that will affect your healthcare.

Joel Kahn, MD, FAAC Medical Background

Joel Kahn, MD, FACC of Detroit, Michigan, is a practicing cardiologist, and a Clinical Professor of Medicine at Wayne State University School of Medicine. He graduated Summa Cum Laude from the University of Michigan Medical School. Known as “America’s Healthy Heart Doc”. Dr. Kahn has triple board certification in Internal Medicine, Cardiovascular Medicine, and Interventional Cardiology. He was the first physician in the world to certify in Metabolic Cardiology with A4M/MMI and the University of South Florida. He founded the Kahn Center for Cardiac Longevity in Bingham Farms, MI in 2015.

DrTalks Videos with Heart Expert – Joel Kahn, MD, FACC

Reversing Heart Disease Naturally Summit Live Q&A

Reversing Heart Disease with Precision Cardiology: The Kahn Center Method

Palpitations To Atrial Fibrillation: How To Diagnose And Treat Naturally

Reference:

Novo Nordisk. (2023). Novo Nordisk A/S: Semaglutide 2.4 mg reduces the risk of major adverse cardiovascular events by 20% in adults with overweight or obesity in the SELECT trial. Novo Nordisk. Read it here.

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Bret Gregory
Bret Gregory
13 days ago

The recent announcement from Novo Nordisk regarding their weight loss drug, Wegovy, and its potential to reduce the risk of heart disease by 20% is indeed a breakthrough that piques interest. As the founder of DrTalks, I find myself both excited and cautiously optimistic about the possibilities this report opens up for individuals struggling with weight management and heart health concerns. The SELECT trial, with its focus on the effects of semaglutide in overweight or obese non-diabetic patients, marks a significant step forward in our understanding of weight loss medications and their broader health implications.

Dr. Joel Kahn’s expert analysis, provided on our DrTalks YouTube Channel, sheds light on the complexity of interpreting these findings. His explanation of the difference between relative risk reduction and absolute risk reduction is particularly enlightening, emphasizing the importance of digging deeper into the data to understand the true impact of Wegovy on heart health. As he rightly points out, the devil is in the details, and the full study’s publication will be critical to fully grasp the medication’s potential benefits and limitations.

In the meantime, Dr. Kahn’s advice to maintain cardiovascular health through fitness programs and healthy diet programs, such as a whole food plant-based diet, remains sage. These lifestyle choices have proven benefits for heart health and can be powerful allies in our journey towards wellness.

We eagerly await the full results of the SELECT trial and anticipate further insights into how Wegovy might be integrated into broader strategies for managing cardiovascular risk among those overweight or obese. At DrTalks, we remain committed to bringing our audience the latest and most credible health information, and this study represents precisely the kind of pioneering research we aim to highlight.

I encourage our community to stay tuned for updates on this important topic and to continue engaging with proven strategies to support heart health. Together, we can navigate the complexities of health and wellness with informed decisions that prioritize our long-term well-being.

Daniel Chantigian
Daniel Chantigian, MS
Learn more

When it comes to complex scientific or medical topics, Daniel can successfully communicate with any audience via writing, social media, lecturing, and one-on-one discussions. Over the past decade, he developed these skills as a researcher at the University of Minnesota and the Mayo Clinic, as a lecturer at the University...

Join the discussion

or to comment
1 Comment
Oldest
Newest Most Voted
Inline Feedbacks
View all comments
Bret Gregory
Bret Gregory
13 days ago

The recent announcement from Novo Nordisk regarding their weight loss drug, Wegovy, and its potential to reduce the risk of heart disease by 20% is indeed a breakthrough that piques interest. As the founder of DrTalks, I find myself both excited and cautiously optimistic about the possibilities this report opens up for individuals struggling with weight management and heart health concerns. The SELECT trial, with its focus on the effects of semaglutide in overweight or obese non-diabetic patients, marks a significant step forward in our understanding of weight loss medications and their broader health implications.

Dr. Joel Kahn’s expert analysis, provided on our DrTalks YouTube Channel, sheds light on the complexity of interpreting these findings. His explanation of the difference between relative risk reduction and absolute risk reduction is particularly enlightening, emphasizing the importance of digging deeper into the data to understand the true impact of Wegovy on heart health. As he rightly points out, the devil is in the details, and the full study’s publication will be critical to fully grasp the medication’s potential benefits and limitations.

In the meantime, Dr. Kahn’s advice to maintain cardiovascular health through fitness programs and healthy diet programs, such as a whole food plant-based diet, remains sage. These lifestyle choices have proven benefits for heart health and can be powerful allies in our journey towards wellness.

We eagerly await the full results of the SELECT trial and anticipate further insights into how Wegovy might be integrated into broader strategies for managing cardiovascular risk among those overweight or obese. At DrTalks, we remain committed to bringing our audience the latest and most credible health information, and this study represents precisely the kind of pioneering research we aim to highlight.

I encourage our community to stay tuned for updates on this important topic and to continue engaging with proven strategies to support heart health. Together, we can navigate the complexities of health and wellness with informed decisions that prioritize our long-term well-being.

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