Full Transcript Introduction to Methylene Blue 0:03 This also uses in the palliative or 0:03 This also uses in the palliative or helping with symptoms part of cancer 0:06 helping with symptoms part of cancer 0:06 helping with symptoms part of cancer care. 0:11 Welcome to my YouTube channel. I'm Dr. 0:11 Welcome to my YouTube channel. I'm Dr. A. How can we use methylene blue, an old 0:15 A. How can we use methylene blue, an old 0:15 A. How can we use methylene blue, an old drug for new uses? And what are those 0:18 drug for new uses? And what are those 0:18 drug for new uses? And what are those uses? Methylene blue is one of the 0:20 uses? Methylene blue is one of the 0:20 uses? Methylene blue is one of the oldest, or if not the oldest, synthetic 0:23 oldest, or if not the oldest, synthetic 0:23 oldest, or if not the oldest, synthetic medication. So, have you heard of 0:25 medication. So, have you heard of 0:25 medication. So, have you heard of methylene blue? But how can a very old 0:27 methylene blue? But how can a very old 0:27 methylene blue? But how can a very old drug like this suddenly become something 0:30 drug like this suddenly become something 0:30 drug like this suddenly become something that we use for totally different and 0:32 that we use for totally different and 0:32 that we use for totally different and new purposes? So, let's dive into this 0:35 new purposes? So, let's dive into this 0:35 new purposes? So, let's dive into this methylene blue discussion. And I've 0:37 methylene blue discussion. And I've 0:37 methylene blue discussion. And I've divided this up into kind of the top 10 0:40 divided this up into kind of the top 10 0:40 divided this up into kind of the top 10 factors to consider around this old drug 0:44 factors to consider around this old drug 0:44 factors to consider around this old drug that is being used in a new way. It is a
How It Works in the Body 0:46 that is being used in a new way. It is a 0:46 that is being used in a new way. It is a drug, so it is done by prescription, and 0:49 drug, so it is done by prescription, and 0:49 drug, so it is done by prescription, and that is a good thing. So, the first 0:51 that is a good thing. So, the first 0:51 that is a good thing. So, the first thing that you want to remember is a low 0:53 thing that you want to remember is a low 0:53 thing that you want to remember is a low dose methylene blue. It doesn't take 0:55 dose methylene blue. It doesn't take 0:55 dose methylene blue. It doesn't take very much. It's an outside, meaning it's 0:58 very much. It's an outside, meaning it's 0:58 very much. It's an outside, meaning it's not part of our body. Methylene blue 1:00 not part of our body. Methylene blue 1:00 not part of our body. Methylene blue doesn't exist in our body. But the big 1:02 doesn't exist in our body. But the big 1:02 doesn't exist in our body. But the big thing that it does is it can go to your 1:05 thing that it does is it can go to your 1:05 thing that it does is it can go to your mitochondria, which help you make the 1:07 mitochondria, which help you make the 1:07 mitochondria, which help you make the energy in your body. And it can be an 1:09 energy in your body. And it can be an 1:09 energy in your body. And it can be an accessory electron carrier, meaning 1:13 accessory electron carrier, meaning 1:13 accessory electron carrier, meaning beyond where your nutrients go into your 1:15 beyond where your nutrients go into your 1:15 beyond where your nutrients go into your body, and we take certain things like 1:18 body, and we take certain things like 1:18 body, and we take certain things like the vitamin B3 nicotinamide, turn it 1:20 the vitamin B3 nicotinamide, turn it 1:20 the vitamin B3 nicotinamide, turn it into some you know, kind of advanced 1:22 into some you know, kind of advanced 1:22 into some you know, kind of advanced nicotinamides, and help that run through 1:25 nicotinamides, and help that run through 1:25 nicotinamides, and help that run through the mitochondria to make energy by 1:27 the mitochondria to make energy by 1:27 the mitochondria to make energy by moving electrons around. Methylene blue 1:30 moving electrons around. Methylene blue 1:30 moving electrons around. Methylene blue can come in in support of that, and 1:32 can come in in support of that, and 1:33 can come in in support of that, and actually add in more electron carrying 1:36 actually add in more electron carrying 1:36 actually add in more electron carrying capacity. More electron carrying 1:38 capacity. More electron carrying 1:38 capacity. More electron carrying capacity equals more energy. Now, you 1:41 capacity equals more energy. Now, you 1:41 capacity equals more energy. Now, you might be saying, "Oh, so it's just going 1:42 might be saying, "Oh, so it's just going 1:42 might be saying, "Oh, so it's just going to jack up my energy?" Well, wouldn't 1:45 to jack up my energy?" Well, wouldn't 1:45 to jack up my energy?" Well, wouldn't caffeine do that or something, right? 1:46 caffeine do that or something, right? 1:46 caffeine do that or something, right? Well, it's not just for improving 1:49 Well, it's not just for improving 1:49 Well, it's not just for improving energy. When we talk about improving 1:51 energy. When we talk about improving 1:51 energy. When we talk about improving energy in the mitochondria, what we need 1:52 energy in the mitochondria, what we need 1:52 energy in the mitochondria, what we need to remember is most disorder and disease
Why Mitochondria Matter for Disease 1:55 to remember is most disorder and disease 1:55 to remember is most disorder and disease of the cell starts from the mitochondria 1:57 of the cell starts from the mitochondria 1:57 of the cell starts from the mitochondria and works its way out. Many disorders 1:59 and works its way out. Many disorders 1:59 and works its way out. Many disorders and diseases are when the mitochondria 2:01 and diseases are when the mitochondria 2:01 and diseases are when the mitochondria slow down or get broken and they can't 2:04 slow down or get broken and they can't 2:04 slow down or get broken and they can't produce energy for the cell, so the cell 2:06 produce energy for the cell, so the cell 2:06 produce energy for the cell, so the cell gets broken and slows down and then 2:08 gets broken and slows down and then 2:08 gets broken and slows down and then often it goes away. So the methylene 2:10 often it goes away. So the methylene 2:10 often it goes away. So the methylene blue helping with the energy is actually 2:12 blue helping with the energy is actually 2:12 blue helping with the energy is actually helping at the base level for many 2:14 helping at the base level for many 2:15 helping at the base level for many chronic illnesses, certain conditions 2:17 chronic illnesses, certain conditions 2:18 chronic illnesses, certain conditions and cancer, other things of that nature. 2:20 and cancer, other things of that nature. 2:20 and cancer, other things of that nature. The other thing which is really 2:21 The other thing which is really 2:21 The other thing which is really interesting is is that methylene blue 2:23 interesting is is that methylene blue 2:23 interesting is is that methylene blue adds to your natural processes that make 2:27 adds to your natural processes that make 2:27 adds to your natural processes that make the electron transport system work. 2:29 the electron transport system work. 2:29 the electron transport system work. Methylene blue actually adds on to it. 2:32 Methylene blue actually adds on to it. 2:32 Methylene blue actually adds on to it. It's not just priming it. It actually 2:34 It's not just priming it. It actually 2:34 It's not just priming it. It actually adds extra electron support to go 2:36 adds extra electron support to go 2:36 adds extra electron support to go through the mitochondria. So it's sort 2:38 through the mitochondria. So it's sort 2:38 through the mitochondria. So it's sort of double energy producing. It's been 2:41 of double energy producing. It's been 2:41 of double energy producing. It's been looked at a lot in a number of areas.
Brain Health and Neurological Benefits 2:44 looked at a lot in a number of areas. 2:44 looked at a lot in a number of areas. One big area is in the neurology area 2:47 One big area is in the neurology area 2:47 One big area is in the neurology area because trying to get the brain repaired 2:49 because trying to get the brain repaired 2:49 because trying to get the brain repaired after certain types of diseases and 2:51 after certain types of diseases and 2:51 after certain types of diseases and disorders is quite big problem and the 2:53 disorders is quite big problem and the 2:53 disorders is quite big problem and the brain has some of the most dense areas 2:55 brain has some of the most dense areas 2:55 brain has some of the most dense areas of mitochondria in the body. So the 2:57 of mitochondria in the body. So the 2:57 of mitochondria in the body. So the first paper is targeting mitochondrial 3:00 first paper is targeting mitochondrial 3:00 first paper is targeting mitochondrial dysfunction and central nervous system 3:04 dysfunction and central nervous system 3:04 dysfunction and central nervous system injury using methylene blue. If you have 3:06 injury using methylene blue. If you have 3:06 injury using methylene blue. If you have a high density mitochondrial tissue like 3:09 a high density mitochondrial tissue like 3:09 a high density mitochondrial tissue like the brain, you're going to have a high 3:12 the brain, you're going to have a high 3:12 the brain, you're going to have a high density need for repair there. So 3:14 density need for repair there. So 3:14 density need for repair there. So they've actually done studies both with 3:16 they've actually done studies both with 3:16 they've actually done studies both with animals and humans in trying to target 3:19 animals and humans in trying to target 3:19 animals and humans in trying to target injured brains and get them back online. 3:22 injured brains and get them back online. 3:22 injured brains and get them back online. And how often do we hear about traumatic 3:24 And how often do we hear about traumatic 3:25 And how often do we hear about traumatic brain injury, post-COVID illness, brain 3:27 brain injury, post-COVID illness, brain 3:27 brain injury, post-COVID illness, brain fog, chronic headaches, all those other 3:29 fog, chronic headaches, all those other 3:29 fog, chronic headaches, all those other things, things of that nature. Also,
Memory, Connectivity, and Cognitive Function 3:31 things, things of that nature. Also, 3:31 things, things of that nature. Also, they've looked at the actual thought 3:33 they've looked at the actual thought 3:33 they've looked at the actual thought processes and that what they call 3:35 processes and that what they call 3:35 processes and that what they call connectivity in the brain. So another 3:37 connectivity in the brain. So another 3:37 connectivity in the brain. So another paper talks about methylene blue through 3:39 paper talks about methylene blue through 3:39 paper talks about methylene blue through its effect in the mitochondria helping 3:42 its effect in the mitochondria helping 3:42 its effect in the mitochondria helping to modulate the functional connectivity 3:45 to modulate the functional connectivity 3:45 to modulate the functional connectivity of brain tissue. And this this looks at 3:47 of brain tissue. And this this looks at 3:47 of brain tissue. And this this looks at a lot of things such as not only our 3:49 a lot of things such as not only our 3:49 a lot of things such as not only our processing and executive function, but 3:51 processing and executive function, but 3:51 processing and executive function, but also things like memory problems and 3:53 also things like memory problems and 3:53 also things like memory problems and dementia, potentials for use in those 3:55 dementia, potentials for use in those 3:56 dementia, potentials for use in those areas. So, again, a really not uncommon 3:59 areas. So, again, a really not uncommon 3:59 areas. So, again, a really not uncommon area of dysfunction that methylene blue 4:01 area of dysfunction that methylene blue 4:01 area of dysfunction that methylene blue blue, this very old drug for new 4:03 blue, this very old drug for new 4:03 blue, this very old drug for new purposes, may have a role in. Another 4:06 purposes, may have a role in. Another 4:06 purposes, may have a role in. Another one related to all that is actual
Neurodegeneration and Healthy Aging 4:08 one related to all that is actual 4:08 one related to all that is actual looking at in science at protection from 4:11 looking at in science at protection from 4:11 looking at in science at protection from neurodegeneration. Well, we all can 4:13 neurodegeneration. Well, we all can 4:13 neurodegeneration. Well, we all can undergo neurodegeneration. We all do at 4:15 undergo neurodegeneration. We all do at 4:15 undergo neurodegeneration. We all do at a certain point, but it can be sped up 4:18 a certain point, but it can be sped up 4:18 a certain point, but it can be sped up by underlying genetic disorders, 4:20 by underlying genetic disorders, 4:20 by underlying genetic disorders, traumatic brain injuries, chronic brain 4:23 traumatic brain injuries, chronic brain 4:23 traumatic brain injuries, chronic brain trauma, chronic chemical traumas, 4:25 trauma, chronic chemical traumas, 4:25 trauma, chronic chemical traumas, infectious traumas. In the neurology 4:28 infectious traumas. In the neurology 4:28 infectious traumas. In the neurology literature, they talk about COVID being 4:30 literature, they talk about COVID being 4:30 literature, they talk about COVID being like a traumatic brain injury. So, 4:32 like a traumatic brain injury. So, 4:32 like a traumatic brain injury. So, again, you can have infectious traumas, 4:34 again, you can have infectious traumas, 4:34 again, you can have infectious traumas, et cetera. And they there are papers 4:36 et cetera. And they there are papers 4:36 et cetera. And they there are papers about the use of methylene blue with 4:39 about the use of methylene blue with 4:39 about the use of methylene blue with neurodegenerative conditions. There's 4:41 neurodegenerative conditions. There's 4:41 neurodegenerative conditions. There's also just some speculative papers about 4:44 also just some speculative papers about 4:44 also just some speculative papers about helping us with healthy aging. But, it 4:47 helping us with healthy aging. But, it 4:47 helping us with healthy aging. But, it would kind of make sense if the sum 4:48 would kind of make sense if the sum 4:48 would kind of make sense if the sum total of our health is largely 4:51 total of our health is largely 4:51 total of our health is largely predicated on whether all of our cells 4:54 predicated on whether all of our cells 4:54 predicated on whether all of our cells have the right amount of electron 4:57 have the right amount of electron 4:57 have the right amount of electron transfer and the right amount of 4:59 transfer and the right amount of 4:59 transfer and the right amount of mitochondrial function that makes our 5:01 mitochondrial function that makes our 5:01 mitochondrial function that makes our cells healthier. The healthier all that 5:03 cells healthier. The healthier all that 5:03 cells healthier. The healthier all that is, the healthier we are going to be. 5:05 is, the healthier we are going to be. 5:05 is, the healthier we are going to be. And I think that's where they're going 5:06 And I think that's where they're going 5:06 And I think that's where they're going in that particular paper. And uh got a 5:09 in that particular paper. And uh got a 5:09 in that particular paper. And uh got a paper in there that's looking at
Chronic Infections and Lyme Disease 5:11 paper in there that's looking at 5:11 paper in there that's looking at specifically tick-borne diseases. We 5:14 specifically tick-borne diseases. We 5:14 specifically tick-borne diseases. We know about Lyme disease, but there's a 5:15 know about Lyme disease, but there's a 5:15 know about Lyme disease, but there's a lot of other diseases related and 5:18 lot of other diseases related and 5:18 lot of other diseases related and methylene blue. It's used a lot in the 5:20 methylene blue. It's used a lot in the 5:20 methylene blue. It's used a lot in the chronic Lyme community, et cetera. How's 5:23 chronic Lyme community, et cetera. How's 5:23 chronic Lyme community, et cetera. How's that connect? It connects on a number of 5:25 that connect? It connects on a number of 5:25 that connect? It connects on a number of levels. One is there's a lot of energy 5:27 levels. One is there's a lot of energy 5:27 levels. One is there's a lot of energy depletion, but also damage to the 5:30 depletion, but also damage to the 5:30 depletion, but also damage to the mitochondria that occur when you have a 5:32 mitochondria that occur when you have a 5:32 mitochondria that occur when you have a chronic infectious disease such as, you 5:35 chronic infectious disease such as, you 5:35 chronic infectious disease such as, you know, Lyme or Epstein-Barr or any of the 5:37 know, Lyme or Epstein-Barr or any of the 5:37 know, Lyme or Epstein-Barr or any of the other chronic infections that people 5:38 other chronic infections that people 5:38 other chronic infections that people get. So, you get damage eventually to 5:40 get. So, you get damage eventually to 5:40 get. So, you get damage eventually to the electron transport chain in the 5:42 the electron transport chain in the 5:42 the electron transport chain in the mitochondria and our and our energy. 5:44 mitochondria and our and our energy. 5:44 mitochondria and our and our energy. But, the other side of it is our immune 5:46 But, the other side of it is our immune 5:46 But, the other side of it is our immune system uses a lot of mitochondrial 5:48 system uses a lot of mitochondrial 5:48 system uses a lot of mitochondrial energy to keep up with stuff. And so 5:50 energy to keep up with stuff. And so 5:50 energy to keep up with stuff. And so imagine the beating that takes in a 5:52 imagine the beating that takes in a 5:52 imagine the beating that takes in a chronic infectious disease setting. This 5:55 chronic infectious disease setting. This 5:55 chronic infectious disease setting. This also really cool set of papers that I I 5:59 also really cool set of papers that I I 5:59 also really cool set of papers that I I just presented one of these at a
Chemotherapy Damage and Mitochondrial DNA Repair 6:01 just presented one of these at a 6:01 just presented one of these at a hospital to the oncology department 6:03 hospital to the oncology department 6:03 hospital to the oncology department looking at use of methylene blue in 6:07 looking at use of methylene blue in 6:07 looking at use of methylene blue in repairing the damage to the 6:10 repairing the damage to the 6:10 repairing the damage to the mitochondrial DNA. So there's specific 6:13 mitochondrial DNA. So there's specific 6:13 mitochondrial DNA. So there's specific DNA that help us remake our mitochondria 6:16 DNA that help us remake our mitochondria 6:16 DNA that help us remake our mitochondria after particular type of chemotherapy 6:18 after particular type of chemotherapy 6:18 after particular type of chemotherapy induced injury. One of the problems with 6:20 induced injury. One of the problems with 6:20 induced injury. One of the problems with chemotherapy is that it goes in and it 6:23 chemotherapy is that it goes in and it 6:23 chemotherapy is that it goes in and it might help you with your cancer, but 6:25 might help you with your cancer, but 6:25 might help you with your cancer, but it's really hard on the rest of your 6:26 it's really hard on the rest of your 6:26 it's really hard on the rest of your body. It might be hard on your heart or 6:28 body. It might be hard on your heart or 6:28 body. It might be hard on your heart or your brain or your kidneys or you some 6:30 your brain or your kidneys or you some 6:30 your brain or your kidneys or you some other important part of you. In this 6:32 other important part of you. In this 6:32 other important part of you. In this particular type of chemotherapy, it's 6:33 particular type of chemotherapy, it's 6:33 particular type of chemotherapy, it's actually damaged directly to the 6:35 actually damaged directly to the 6:35 actually damaged directly to the mitochondrial DNA. If they get damaged, 6:38 mitochondrial DNA. If they get damaged, 6:38 mitochondrial DNA. If they get damaged, then they can't really form new 6:39 then they can't really form new 6:39 then they can't really form new mitochondria appropriately. And if it's 6:41 mitochondria appropriately. And if it's 6:41 mitochondria appropriately. And if it's in a sensitive area like say your 6:43 in a sensitive area like say your 6:43 in a sensitive area like say your kidneys, then you get kidney damage. But 6:46 kidneys, then you get kidney damage. But 6:46 kidneys, then you get kidney damage. But the kidney damage really starts at the 6:47 the kidney damage really starts at the 6:47 the kidney damage really starts at the DNA level. And they've now through 6:49 DNA level. And they've now through 6:49 DNA level. And they've now through modern science found out ways why this 6:52 modern science found out ways why this 6:52 modern science found out ways why this happens, okay? What they're looking at 6:54 happens, okay? What they're looking at 6:54 happens, okay? What they're looking at is methylene blue can actually go in and 6:57 is methylene blue can actually go in and 6:57 is methylene blue can actually go in and it can undo the mitochondrial DNA 7:01 it can undo the mitochondrial DNA 7:01 it can undo the mitochondrial DNA damage, actually turn it off so that the 7:04 damage, actually turn it off so that the 7:04 damage, actually turn it off so that the cells have a chance to operate normally 7:07 cells have a chance to operate normally 7:07 cells have a chance to operate normally and build normal mitochondria even after 7:09 and build normal mitochondria even after 7:09 and build normal mitochondria even after an insult from particular types of 7:11 an insult from particular types of 7:11 an insult from particular types of chemotherapy. This also uses in the
Cancer Care and Mucositis Relief 7:15 chemotherapy. This also uses in the 7:15 chemotherapy. This also uses in the palliative or helping with symptoms part 7:17 palliative or helping with symptoms part 7:18 palliative or helping with symptoms part of cancer care. And one of the things 7:20 of cancer care. And one of the things 7:20 of cancer care. And one of the things that's really horrible side effect with 7:22 that's really horrible side effect with 7:23 that's really horrible side effect with with a lot of chemotherapies they call 7:24 with a lot of chemotherapies they call 7:24 with a lot of chemotherapies they call mucositis. But it can be anywhere from 7:26 mucositis. But it can be anywhere from 7:26 mucositis. But it can be anywhere from your lips all the way through your 7:28 your lips all the way through your 7:28 your lips all the way through your digestive tract where you can get 7:30 digestive tract where you can get 7:30 digestive tract where you can get swollen, you can get inflamed, it can be 7:32 swollen, you can get inflamed, it can be 7:32 swollen, you can get inflamed, it can be very painful. And in certain cases, the 7:35 very painful. And in certain cases, the 7:35 very painful. And in certain cases, the pain is so bad you can't eat or drink. 7:37 pain is so bad you can't eat or drink. 7:37 pain is so bad you can't eat or drink. It can be that bad. And so mucositis is 7:40 It can be that bad. And so mucositis is 7:40 It can be that bad. And so mucositis is always one of those things we're working 7:41 always one of those things we're working 7:41 always one of those things we're working with with cancer patients just to try 7:43 with with cancer patients just to try 7:43 with with cancer patients just to try and keep it to a minimum or at bay. 7:45 and keep it to a minimum or at bay. 7:45 and keep it to a minimum or at bay. Well, they looked at treatment of 7:47 Well, they looked at treatment of 7:47 Well, they looked at treatment of mucositis which, you know, there are 7:49 mucositis which, you know, there are 7:49 mucositis which, you know, there are things to calm it down pallatively, but 7:52 things to calm it down pallatively, but 7:52 things to calm it down pallatively, but actually to treat it underlying there's 7:53 actually to treat it underlying there's 7:53 actually to treat it underlying there's not as many things, but treatment of 7:55 not as many things, but treatment of 7:55 not as many things, but treatment of mucositis in pediatric patients and they 7:58 mucositis in pediatric patients and they 7:58 mucositis in pediatric patients and they actually had very positive results with 8:01 actually had very positive results with 8:01 actually had very positive results with a small trial in in children, so human 8:04 a small trial in in children, so human 8:04 a small trial in in children, so human trial in children. And then there's more 8:06 trial in children. And then there's more 8:06 trial in children. And then there's more papers coming out about this and I 8:07 papers coming out about this and I 8:07 papers coming out about this and I mentioned it earlier, but repurposing
COVID-19 and Long COVID Applications 8:10 mentioned it earlier, but repurposing 8:10 mentioned it earlier, but repurposing methylene blue in the management of 8:12 methylene blue in the management of 8:12 methylene blue in the management of COVID-19. If we think about it, among 8:14 COVID-19. If we think about it, among 8:14 COVID-19. If we think about it, among the many many reasons that SARS-CoV-2 8:18 the many many reasons that SARS-CoV-2 8:18 the many many reasons that SARS-CoV-2 COVID-19 creates trouble in the body and 8:21 COVID-19 creates trouble in the body and 8:21 COVID-19 creates trouble in the body and creates long COVID and all those bad 8:22 creates long COVID and all those bad 8:23 creates long COVID and all those bad things, a lot of them are because of the 8:25 things, a lot of them are because of the 8:25 things, a lot of them are because of the immunologic dysregulation that that that 8:28 immunologic dysregulation that that that 8:28 immunologic dysregulation that that that virus has like many other infections, 8:30 virus has like many other infections, 8:30 virus has like many other infections, but SARS-CoV-2 is a little more 8:32 but SARS-CoV-2 is a little more 8:32 but SARS-CoV-2 is a little more aggressive in some areas and then that 8:34 aggressive in some areas and then that 8:34 aggressive in some areas and then that immunologic deregulation beats up on the 8:37 immunologic deregulation beats up on the 8:37 immunologic deregulation beats up on the cells, beats up on the mitochondria, 8:39 cells, beats up on the mitochondria, 8:39 cells, beats up on the mitochondria, takes people some people with long COVID 8:41 takes people some people with long COVID 8:41 takes people some people with long COVID a long time to recover. So, they're 8:43 a long time to recover. So, they're 8:43 a long time to recover. So, they're looking at repurposing methylene blue 8:45 looking at repurposing methylene blue 8:45 looking at repurposing methylene blue just like we talked about with all these 8:47 just like we talked about with all these 8:47 just like we talked about with all these other things in the setting of COVID and 8:49 other things in the setting of COVID and 8:49 other things in the setting of COVID and long COVID as well. So, those are just 8:51 long COVID as well. So, those are just 8:51 long COVID as well. So, those are just 10 of many many many areas in science 8:54 10 of many many many areas in science 8:54 10 of many many many areas in science that we're looking at the use of
Key Safety Reminders 8:56 that we're looking at the use of 8:56 that we're looking at the use of repurposed methylene blue. Number one, 8:58 repurposed methylene blue. Number one, 8:58 repurposed methylene blue. Number one, remember it is a drug, it has to be 9:00 remember it is a drug, it has to be 9:00 remember it is a drug, it has to be monitored and dosed appropriately, 9:02 monitored and dosed appropriately, 9:02 monitored and dosed appropriately, should never be ordered online and dosed 9:05 should never be ordered online and dosed 9:05 should never be ordered online and dosed on your own, etc. Number two, you need a 9:08 on your own, etc. Number two, you need a 9:08 on your own, etc. Number two, you need a healthcare provider who is used to using 9:10 healthcare provider who is used to using 9:10 healthcare provider who is used to using methylene blue. And 9:12 methylene blue. And 9:12 methylene blue. And most healthcare providers, everybody's 9:14 most healthcare providers, everybody's 9:14 most healthcare providers, everybody's heard of it for its emergency use in 9:17 heard of it for its emergency use in 9:17 heard of it for its emergency use in certain types of blood disorders, but 9:19 certain types of blood disorders, but 9:20 certain types of blood disorders, but you need a provider who's used to using 9:21 you need a provider who's used to using 9:21 you need a provider who's used to using low-dose methylene blue in these other 9:24 low-dose methylene blue in these other 9:24 low-dose methylene blue in these other settings. Doctor A, I'll see you all on 9:27 settings. Doctor A, I'll see you all on 9:27 settings. Doctor A, I'll see you all on the next video.
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