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Aumatma Simmons, ND, FABNE, MS
Dr. Aumatma is a double board-certified Naturopathic Doctor & Endocrinologist, in practice for 15 years. Dr Aumatma supports badass power couples to create the family of their dreams, and also trains doctors who want to specialize in fertility. She is the best-selling author of "Fertility Secrets: What Your Doctor Didn't... Read More
Dr. Joseph Antoun’s passion is to enhance human healthy longevity. He is the CEO and Chairman of the Board of L-Nutra, a unique Nutrition technology company leading the Food as Medicine movement and developing breakthrough nutri-technologies that profoundly impact how we age and prevent or better manage health conditions. Before... Read More
- Discover how intermittent and prolonged fasting can significantly impact your metabolic health and fertility, offering a pathway to rejuvenation
- Understand the relationship between autophagy, initiated by fasting beyond two days, and its critical role in renewing cells, including those vital for reproduction
- Gather insights into the fasting-mimicking diet and its ability to deliver the benefits of fasting—weight loss, metabolic health improvement, and cellular rejuvenation—without the stress of food deprivation
- This video is part of the Beyond “Infertility”: Navigating Your Path to Parenthood Summit
Aumatma Simmons, ND, Fabine, MS
Hey. Welcome to the Beyond Infertility Summit. I’m your host, Dr. Aumatma. Today we are talking to Dr. Joseph Antoun, whose passion is to enhance human longevity. He is the CEO of L-Nutra, a company that makes a product called ProLon, which you may have heard of. We’re going to have a very interesting conversation with him about fasting and how it impacts fertility. He had a very impressive bio before taking on this role. He was the CEO of Health Systems Reform, a boutique consultancy aimed at elevating public health through reforming health systems, strengthening healthcare management, and improving healthcare delivery. He was the co-director of the Center for Health Policy at the University of Chicago and an adjacent Professor of Health Policy at the Buck Institute for Research on Aging. There are so many amazing accomplishments that Dr. Antoun has been part of. They are leading the way in doing research in nutrition. That isn’t happening elsewhere at this moment in time. Dr. Antoun is going to share a lot of their amazing research and how fasting can support aging, which in turn supports fertility. Let’s get into it. Let’s talk to Dr. Antoun, welcome to the Beyond Infertility Summit. We’re so excited to have you here, and I’m excited to learn more about fasting and how this could support fertility. Let’s jump off with the types of fasting. What are the different ways that people could fast, and the implications of this?
Joseph Antoun, MD, PhD, MPP
Thank you for hosting this. It’s a clinical question because fasting is the number one vibe in the US. Close to eight percent of people in the US practice a certain kind of fasting. It became very popular and a lot of misconceptions behind it. We’ve been doing fasting works for 23 years, so I’m happy to clarify the types and the benefits of each.
In general, there are two types of fasting. There is what we call intermittent fasting, which is anything with zero hours with no food, all the way to two days for eight hours. And then there is something called ProLon Fasting or periodic fasting which then you go over two days, and typically for three to five days. So while we’re in a two-day in a switch. Why does the classification go below or above two days? The body goes through a transition because the first two days you have enough reserves in the body to compensate for the lack of food. You have five storage that you can tap into. You have glycogen as well as these are our reserves. The liver also can dump some calories into the system. I call them the savings, account, the checking account, and the credit.
First, the glycogen; that’s your checking account. Then you go to your savings accounts; that’s fat. Then the liver can credit you with some extra calories through gluconeogenesis. In the first phase of fasting, intermittent fasting, a lot of people do 16 hours, or 18 hours a day, but the body compensates by losing weight and tapping into the reserves, which is important because 73% of Americans are suffering from a weight-related, lifestyle-related, or metabolic-related issue. and losing here some weight will help a little bit with blood pressure will help a bit with blood sugar will help a little bit with cholesterol, etc. Now, when you cross the second day, the body tells the cells, I’m going bankrupt. You’re consuming your checking and savings accounts very quickly. I’m not in danger. Therefore, I’m going to ask every cell, because every cell lives on calories, to rejuvenate and go into an optimal stage of performance so that we all survive as a unit called the body. So cells after day two, and especially after day three, start going to the rejuvenation process called autophagy, which is induced by fasting. This phenomenon won the Nobel Prize in Medicine in 2016 so very well documented in science. It was a big weapon for our ancestors to stay healthy long enough. They used to die of short-acute diseases, but they were not dying mostly of chronic diseases, aging, etc. Lack of self-rejuvenation is very important, and we’re going to tie it to fertility because a lot of reasons—if not the top two reasons for infertility—are related to metabolic health and aging. Perhaps you can resolve both by helping with metabolic health, which creates insulin resistance, and by increasing the rates of PCOS and the non-spiking of hormones. Probably the other speakers ProLon fasting, the body is biologically younger, and we know we’re more fertile if we’re younger versus if we’re older. So that’s the key and the relationship between fasting and infertility, whether short-term, fast, or intermittent, you have all the metabolic reasons. If you do it longer and faster, you’re helping the cells, including the reproductive system, to go biologically younger. I do have a story here that I wanted to add.
When I first started working on fasting, and I’m talking about over a decade ago, it happened that my father and I were sitting in a business lounge, and we had two other folks, two other guys that were in the chicken farming business, and we were just talking about how my father was interested in investing in that business, and we were talking about how they have big chicken farms and they lay eggs, and they were talking about the egg yields and all of that and how to optimize nutrition for where the chickens lay more eggs per week. They were talking a bit. Then they looked at me and asked me what my work was working I was studying fasting and rejuvenation, and they were completely unimpressed. I thought we had made the biggest discovery in the world: that fasting can help people reverse aging. They were completely unimpressed. When I asked them why they were unimpressed, they said that, in the end, in the chicken farming business, when the chickens start decreasing the egg-laying system, that’s the reproductive system. When they go from six eggs per week to three, four, or two, they put them on a three-day fast. When they put them on a three-day fast, the animal metabolism for three days in animals is equivalent to five days in humans. When they put three, they fast, they lay their feathers, they rejuvenate new feathers, and their egg yielding the reproductive systems goes from two to three times per week back to five to six. Not quite six; not quite optimal. Six out of seven. That’s out of the way. But a good five to six for very well-known fasting for enhancing the reproductive yield of chicken. then we humans never knew that up until the science of fasting uncovered this.
Aumatma Simmons, ND, Fabine, MS
That’s fascinating. It’s almost counterintuitive because when we think of fasting, we’re often thinking of something like a restriction. We’ve been calorically deficient for a period of a while really, when we think about pregnancy, for example, most of us have this idea of eating more. that, like the fertility period before conception, it feels counterintuitive to say that fasting can lead to more reproductive potential rather than less. Do you have any thoughts on that? I’m very curious how we can understand this better.
Joseph Antoun, MD, PhD, MPP
It’s because fasting comes at a price. Water fast has a lot of benefits that we talked about. Weight, metabolic and cell rejuvenation, and aging. But it comes at a cost. Exactly which is the deprivation. I’m depriving, the body, and I’m putting it in a stressful situation? So that’s rejuvenation. The stress is a cost. This is why I, as the CEO of a chemical, L-Nutra, do food nutrition that provides the benefits of fasting, such as metabolic and rejuvenation benefits. This is why we, and I, as the CEO of a chemical, L-Nutra, do food nutrition that provides the benefits of fasting, such as metabolic and rejuvenation benefits. But you didn’t deprive the body before. Certainly, we don’t deprive the body, and we use what is called fasting nutrition. You don’t deprive the body when you want to lose a healthy way or improve your blood sugar control, etc.
That’s exactly what our biggest innovation is—that fasting-mimicking diet, the fasting-mimicking that was served by the National Institute of Health and Taxpayers. For everyone in the U.S. who pays taxes, there’s a good chunk of those that go for research. under an organization called the National Institute of Health, which looks at the top most promising innovations in the U.S. and funds us. We were one of the recipients of over $20 million. This very rarely happens in nutrition because of the science behind fasting, which has tons of benefits. We don’t want to deprive people all the way and have them go through the extreme stress of fasting. Can you develop a nutritional intervention that gives the benefits of fasting, weight loss, muscle protection, metabolic health, and rejuvenation without all of these side effects, I’m feeling super hungry, I’m having a headache, and I’m depriving my body before I become pregnant. This is how we did it. We develop a fasting-mimicking diet. We put 18 universities together: USC, Stanford, the University of Miami, and the University of Milan. The 18 universities came together, and they started testing this new formulation, an all-plant-based natural in five days, you get a box at home. It’s ProLon the low end in every bit of five boxes in it. Then every day you open a box, you eat the food, all plant-based vegan, and then it helps to get the benefits of fasting while you’re nourishing the body.
Aumatma Simmons, ND, Fabine, MS
I’ve done a ProLon fasting before, and it feels very different from other types of fasting in which you are in deprivation mode. I remember being hungry but not hangry like it wasn’t to the point of being irritable, and it was just like a physical hunger instead of what often water fasting will lead to.
Joseph Antoun, MD, PhD, MPP
That was the purpose. ProLon mimics fasting, not deprivation or starvation. It mimics fasting through nourishment. On day one, you have 1100 calories, and on days two, three, four, or five, you have 800 calories per day. It has all the plant-based protein, essential amino acids, and complex carbsm it has vitamins and minerals. It has a nourishment program that still gives you the benefits of fasting. We had to learn how the body detects food and then what receptors are on the cells that detect food. We had to design a special precision formulation that does not allow the body, from a hormonal perspective, to recognize this food and the radars of the cells have three major radars, as we call the nutrient-sensing pathways because they sense the food and the nutrients have to go around them and get to nourishthe cell while helping the cell, doing the rejuvenation, and enhancing that process. The fasting-mimicking diet in many aspects enhance even the benefits of fasting while decreasing the side effects.
Aumatma Simmons, ND, Fabine, MS
That is incredible. I have so many questions, but I want to talk a little bit about the cautions that maybe people, especially those trying to get pregnant, should be aware of. You said you ate 800 calories on most of those days. Why is the ProLon fast limited to five days? Is there a reason for those five days? Can people just do it for a whole month, two months, or however long they have in mind?
Joseph Antoun, MD, PhD, MPP
This is decades of research, and in a lot of clinical strategy and clinical trials, we studied why, in five days, you don’t want to go longer because then you bankrupt the body. In exactly that number five, you don’t want to do less than two because you don’t rejuvenate your cells. It will be fasting only. We talked about that. You don’t want to do ten and 12 at 13, because exactly as you said, you deprive the body of that, so five days was the right amount to get the benefits while still, the body is in rejuvenation and flourishing when you finish ProLon, and a lot of people talk about that, and you’ve done it, and you would have felt you didn’t feel the pressure. You feel higher energy, you feel higher, you’re excited, you’re happy, and you’re confident. You just lost fat. This is critical, even for fertility. It only aids in preferential fat loss and protects the muscle because when you fast, growth hormone levels rise, allowing the muscle to grow.
Many people believe that fasting causes muscle loss. It only aids in preferential fat loss and protects the muscle because when you fast, growth hormone levels rise, allowing the muscle to grow. Many people believe that fasting causes muscle loss. When you fast, the body is shifting investment into the muscle because you’re going to go and find food, but because it’s not a water fast, you’re nourishing withdrawal on the muscle, so there’s a call for the muscle to grow, and then you’re nourishing it. You maintain lean body mass. At the five days we need to ProLon, now we have over a million consumers. With most to come things that people talk about are feeling great, strong, and reinvigorated. It’s a rejuvenation and not deprivation.
But if you do ten days of ProLon, then you’re going to start getting deprived. This is not what we want. You don’t do ProLon while pregnant. This is an important way we’re saying you do ProLon to get your biological age younger, which will hopefully help with insulin resistance. We have trials showing a major drop in insulin resistance; one trial showed a 69% drop in insulin resistance if you do ProLon once a month for six months. So five days, month one, five days, month two, five days monthly, all the way to six days. We’re seeing a major drop in insulin resistance—59%. We’re seeing better control of sugar. We’re seeing HB once you drop by 1.4 points out of the metabolic positive metabolic changes that happen there.
We know that the age of the cells is what we call autophagy in rejuvenation. Now we have data to support that. Plus, we just published two weeks ago, a major article in one of Nature’s papers: Nature is the number one science journal of the world. Nature Communication is a paper under nature. We just published an article showing 2.5 years on average of bio-age reversal when you do three cycles of ProLon. If you do three points per year, 15 days only per 365 days, the changes that the body goes through have a reversed the bio-age score by 2.5 years/ Metabolic reset, and age reversal, reinvigorating the reproductive system is very important; it’s one of the youngest systems. It needs that youth and that vibrance to increase fertile both in men and women.
Aumatma Simmons, ND, Fabine, MS
Some tests are coming out that are able to measure essentially like epigenetics and indicate what your reproductive age is. Then there’s another one that is like general aging. How well are you aging? How old does your body think you are, rather than how old you are? Those tests are very interesting because, on average, the women who will potentially struggle with fertility are going to be the ones who are 30, but their bodies think they’re 40. If there is a huge discrepancy between your biological age and your reproductive age, then the body’s like, “Well, I’m not doing this. I’m already 40,” and then, like, there are lots of women that also have premature ovarian insufficiency or failure. That’s where the ovaries are not producing or not having enough follicles to grow, ovulate, and cycle, which makes fertility very challenging, of course. In those women, I can see the potential of doing this, reversing their age, and supporting their rejuvenation from the perspective of, we now have instead of your body thinking you’re 40, it’s thinking you’re 35. That’s a win.
Joseph Antoun, MD, PhD, MPP
100%. I went to the top of the naturopathic schools right at Harvard. I used to disrespect all this, like nutrition, lifestyle, and supplements, and after decades of work on this, I just remember one time there was a big aha moment in my head, like infertility is increasing, diabetes is increasing, cancer is increasing, Alzheimer’s is increasing, and obesity is increasing. Why is everything increasing? We’re spending more on health care. It all goes down to our lifestyle: we’re changing more stress, getting less sleep, picking up weight, becoming more insulin resistant, and aging faster. I’m trying to explain here to everyone listening, men and women, that because of this stressful lifestyle, because of all the changes in your diet, in your sleep, in your happiness, you are less happy. It’s accelerating the age of your body. It’s making you feel down, including in your reproductive system. Therefore, it’s also impacting your thyroid. It may not be at the level where you think it is. Then, you have an issue with the thyroid. It’s just that it’s creating adrenaline fatigue.
The entire engine of vibrance in the body is being cut down, and your age is accelerating faster. This is why you get into it, and I’m saying this to show people that there are things that they can do and that matter they can put things in their own hands, like ProLon, eating healthy, or sleeping better. They will resolve the vast majority of their problems. Because when you go to your traditional doctor and again, I’m coming from there, it just is going to go back to, if it’s genetics or if you have maybe one disease that we don’t find a disease, they don’t screen for some, this is almost like a failure and vibrance filter. Therefore, it’s genetics or it’s idiopathic, and we’ll go with doing IVF or we started doing this or we started doing that. Yes, this is all important, and yes, this can help. But before you get depressed and before you feel helpless, what happens to a couple at the end of their life they get into this and learn helplessness. I’m helpless. No, you’re not it. Just go back and think about the reproductive system, which is a young system within you, and how it responds to your vibrancy to your youthfulness. You get to go back and become younger, and you become younger when you work on five pillars: nutrition, eating healthy but very important, and three cycles of ProLon fasting to reinvigorate that vibrance. It’s your exercise. Make sure you exercise. It’s your stress, it’s your sleep, and it’s your happiness. Work on these pillars and your body’s vibrance, your healthy longevity get reinvigorated, and you’re going to be healthy, for it’s ultimately going to help your risk of diabetes, your risk of cancer, your risk of Alzheimer’s, all those things that I never learned in medical school. Again, I’m proud that’s Harvard, that’s Hopkins. I was director of Health Policy at the University of Chicago, one of the top schools. They never say now, up until I went into lifestyle medicine and learned that most of the things we struggle with are coming from things we can change within our lives. We weren’t here to think about those and go to the starting date and work on your body vibrance, your body aging. Then, if you don’t succeed yes, there are medicines. Yes, there are injections, you can do more to succeed.
Aumatma Simmons, ND, Fabine, MS
I completely agree with you. One of my favorite quotes is that fertility is an outpouring of vitality. When we have that vital energy, that vital state, then fertility just happens. It’s a byproduct or a side effect. It’s not something that we have to actively work at if we have all of the other things working optimally.
Joseph Antoun, MD, PhD, MPP
100% and these like PCOS and this and sperm weakness and why they’re increasing of their genetics. If they do it, why they increase? Would changing our lifestyle with decreasing our vitality or decreasing our vibrancy any faster it we’re depleting our body and this is exactly that. In a lot of that is sub disease, there’s thyroid fatigue, the testosterone and the estrogen is not spiking in the body because of the insulin resistance. It’s like an entire syndrome that is between a disease and a healthy lifestyle, and a lot of us are stuck there. Your traditional allopathic doctor would not diagnose that and would tell you, like, we’re going to do injections. We’re going to do pills; we’re going to inject Ozempics. Now, it’s a huge trend, and then you get to lose muscle. You’re going to be less vibrant afterward. It’s very important to understand that you work on five pillars. Again, your nutrition, your exercise, your stress, your sleep, and your happiness. You need to see a role of rejuvenation within your body. I’m very biased towards prolonged fasting and mimicking, and I have because that’s the only thing that I find in life. I toured the world before I joined L-Nutra and ProLon. My search to find a way to reverse the aging of the body. I didn’t find a natural way to do it, and fasting is like awakening the doctor from within. There are so many philosophers and so many old medical books that talk about fasting, and every divine religion recommends fasting. It’s one way to put the body in check. It’s like when you drive a car in a race, the engine is heated, and the wheels are getting the brakes. You go to the pit stop, and the mechanics come in; they check, they change it, or they change the wheels. This is what fasting is: every day you are putting junk into our bodies. We’re putting in artificial stuff. We’re stressed, and you go fast, you’re just giving your body and your soul a break, and you’re telling them to rejuvenate, clean, detox, and then lose the weight, shed by this bad stuff in the body. Now we have better hosts for fertility. Now our better host for a vibrant health outcome.
Aumatma Simmons, ND, Fabine, MS
What was interesting about doing ProLon when I tried it out was that I didn’t see the weight loss until after I finished the five days. It was almost like the longer three to four weeks after were the biggest weight losses. But I’m not doing anything different. I’m not eating anything different. Nothing’s changed. I just did this ProLon thing. It didn’t seem to do anything at the time. I was like, I feel good. And then to see the impact a few weeks later and be like, “What’s happening? Is this health enough?”
Joseph Antoun, MD, PhD, MPP
Genes are the engine; it’s your cells that are younger. You’re a better performer. You start burning fat as you go because, when we talk about weight loss, most food companies miss out on all of these injectables. What they miss is that it’s about the muscle, not just the intake of it. The muscle is what burns the carbs; it’s what it burns. If you lose the muscle, if you diet every day, you lose the muscle. If you inject the GFP1 the same way, you lose the muscle. It’s when you do the ProLon fasting where you’re just losing fat, you’re protecting muscle, and you’re bringing your cells to a younger, more vibrant age. Your engine is now a better-burning engine because you’re less fat. It’s typical; it tells you that you’ve never been a performer. Then, with time you’re like, “I don’t need so much food, I’m faster, I perform better, I do my task,” And you start losing that weight, sustainably.
Aumatma Simmons, ND, Fabine, MS
It’s pretty incredible. I’m a believer. I want to say I’m biased, but I do see the value of doing a fasting-mimicking diet is indicated. I think everyone can safely do it, except for some people who are calorie-deficient. I had a patient who has a one-year-old now. This is probably two, two and a half years ago when she came in. We looked at her bloodwork, and I was like, you are protein deficient? She’s like, No, I eat protein. We go through her diet. This is like being completely protein-deficient. She didn’t even get enough calories in her daily diet, and she had premature ovarian insufficiency. That’s where we were, like, well, you need to start eating more, like adding protein. Now, if she wanted to have a second baby, I would think the fasting-mimicking diet would help her. But when she was in such a deficient state, I might have given her some time to replenish before starting.
Joseph Antoun, MD, PhD, MPP
Thank you for bringing that up. Four profiles should not do the Prolon. If you are depleted and your BMI is low, it’s like you’re already on a chronic low-calorie and low-protein, so you’re needed. Then you need to get nourished, and then you can do it for just five days to rejuvenate the cells. If you’re already pregnant and lactating, you don’t want to be growing a baby and fasting at the same time. Number three, if you are too old plus, you have chronic conditions at the same time. You’ve got old age plus chronic conditions. We’re not talking about this today because of your facility. That’ ‘s not the case if you have allergies; if you have allergies to nutrition, a lot of the ProLon ingredients are derived from what we call longevity nuts: Macadamia, almonds, etc. If you have allergies to those, you shouldn’t need to the ProLon. Other than that, I’m going to push back a little bit because a lot of people say, Well, should I fast? We are all living in fad today. We are eating all the time, and that’s the wrong thing to do. Our ancestors and humanity lived for hundreds of thousands of years on planet Earth, where there was food, where we could hunt, or when there was the season of fruits and vegetables. There was no food otherwise. It’s so important. Even nature goes to the spring, summer, autumn, winter, rejuvenation spring. Every single living thing, even the bears, they, hibernate. It’s the cyclicity in us. We get it from time to time depleted and then we rejuvenate it in the right way. It’s like companies grow, keep hiring, keep growing, and then suddenly they touch, generating the wrong revenue. But it is like, No, we’ve got to go restructure. Your laptop; the work on it for weeks and then you reset it. It’s the cyclicity of life, and eating all the time is getting us into disease all the time. We have to interject. This is what we were all saying three times a year; we’re not saying we should always fast. Not at all. You should always be nourished. This is the seasonality: every four months you do your ProLon months, unless already pregnant and unless you have allergies to it.
Aumatma Simmons, ND, Fabine, MS
In terms of doing ProLon, is it that they’re doing three months back to back, or is it that you’re doing one and then four months later you do the second one, and then four months after that you do your third?
Joseph Antoun, MD, PhD, MPP
The answer is that it depends on your profile. If you haven’t met the public health goal that you set. You know that I’m insulin resistant, that I’m going to need to shed some weight and that I have the metabolic reason to do it. They do it three times over three months. It’s never in their goal as up to five days. These are always just five days a month, five out of 35. These are the three we just a few months ago at the trial ProLon on five days a month over four months versus a 120-day consecutive Mediterranean diet. Mediterranean diet is ranked as the number one diet in the world by them, a lot of association or the U.S. News and World Report. We went head-to-head just five days a month versus every day with the best diet. We’re well and have the most cardiovascular benefits. We were a little bit superior, for certain, especially the muscle was cyclical here and I cannot repeat it enough. I have to protect our muscles. The muscle is the engine of vibrance, the engine of longevity, the engine of performance, and the engine that burns the carbs. People who did Mediterranean diet have lost a little muscle. People who did ProLon maintain lean body mass. Were critical to maintaining an outcome. If you had that metabolic objective, you do ProLon once a month for three months. If you’re just doing it for vibrance, for healthy aging, and longevity, you don’t need to accelerate your metabolic health or lose a lot of weight fast, then you can do just once every four or three times a month.
Aumatma Simmons, ND, Fabine, MS
You said that ProLon can increase growth hormone, which I was having a little bit of, I wonder if this would help those who seem to have low testosterone levels, which is starting to feel a little bit like an epidemic. There are a lot of men who are just too testosterone-deficient. I’m curious if you’ve seen any studies happening with that in terms of doing pro-on and then seeing outcomes where they have better testosterone levels.
Joseph Antoun, MD, PhD, MPP
We haven’t tested ProLon specifically for people with low testosterone, but what we know is that after you do ProLon, when you lose fat and you protect lean body mass, that puts you in a better state of performance. If you keep exercising after that, and we just launched the longevity protein. For those who do that and become more active, we know that muscle and less fat in men can help testosterone levels, and you’ll help that. I would assume that would be a positive side effect. But we have never directly tested ghrelin for people with low testosterone.
Aumatma Simmons, ND, Fabine, MS
That would be interesting to see. I’m sure you guys get so many requests for studies because the application of this can be vast.
Joseph Antoun, MD, PhD, MPP
We’re currently doing 16 clinical trials all at the same time. This only happens on a large scale by the farm and biotech companies. We are very blessed by our founder. I don’t know if people know Professor Valter Longo, who’s in the top 50 most influential people in health. He’s the author of The Longevity Diet. It is the number one expert on longevity nutrition. Because of those discoveries and the fasting-mimicking, a lot of universities talk to us about collaborating on using ProLon for certain health objectives. We’re running 17 trials now on cancer, diabetes, autoimmune Alzheimer’s, etc., and we’re publishing the results when they come. But we haven’t tried it yet. Testosterone deficiency. If anyone is interested in hearing and letting us know, we’ll be happy to help men and women. We haven’t done a full trial on this. But it’s very interesting because, again, it’s becoming very prevalent.
Aumatma Simmons, ND, Fabine, MS
You mentioned cancer. Is this safe for people who have had cancer previously and maybe are now trying to get pregnant?
Joseph Antoun, MD, PhD, MPP
We do trials with growing, unfortunately, active cancer. assume it would be safe after, but when you have cancer, talking to your doctor is not something that we want to tell you. Of course, you should do it. The different cancers, different stages, and different outcomes differ by emission stage. What I can say is that there’s no reason besides if you’re in the forties, as I mentioned, or if your doctor knows that you have a health condition that prohibits you from going on a fasting regimen. But if you’re in remission, you’ve already had a lot of toxicity in your body from the chemotherapy, the immune therapy, etc. One way is to induce autophagy, or, as you’ve entered the cells, to help get back the vibrance of that. These are things that we only have over eight clinical trials on the use of fasting-mimicking nutrition with. This is not something that I don’t want to position here for health outcomes or to prescribe for those folks. Go back to your doctor. But this is something that we’re paying a lot of attention to.
Aumatma Simmons, ND, Fabine, MS
Yes. It makes sense. Cancer is a little bit of like cell death gone awry. If there is something that helps weird cells die, then that could be a good thing to help lower the.
Joseph Antoun, MD, PhD, MPP
Yes. We call them the zombie cells. When you age, you get a lot of toxicity. Some cells that are just there. They got enough damage; they don’t do much. They create a lot of inflammation in the body. They are not salvageable, and they’re not dying yet. We call them the zombie cells, and we see them a lot when we’re older. They create a lot of information. We call it inflammation because the more you age, the more you have those cells that are hanging around; they’re not dead, but they’re almost dead. They don’t produce the calories without knowing where they are coming in. Because right now when you look at the faces of people who are moving with age, we see changes in our skin.
One of the uses of doing the fasting-mimicking attrition is to help put the body into a difficult position on day three. After three days of fasting, the body looks at the cells and triages. The one is going to perform, and as a unit, we keep it. The one that’s not going to perform, we’re going to kick it out. We’re going to kill it because we see a lot of company restructuring and a lot of things that, in nature, sometimes say, “The thing that doesn’t perform? I cannot hang on to it when times are difficult, and I cannot hang on to it.” We do see that we call it regeneration now. How can I get rid of it when I’m fasting for a longer period? The body’s trying to get rid of underperforming, damaged, or toxic cells.
Aumatma Simmons, ND, Fabine, MS
So good. It’s amazing picking your brain about all things fasting. I am very excited to have you at this summit because we don’t talk about fasting enough, especially in the fertility world. It’s something that I certainly believe in for the right people at the right time. It can be amazing and transformative for your fertility. Thank you for being with us today.
Joseph Antoun, MD, PhD, MPP
I appreciate you. A lot of people think fasting is depletion. Fasting is as reinvigorating as intermittent fasting, as they tell you. I feel the best in my life. ProLon, as they said, is feeling the best coming out of it. It’s a cycle of life. We get it sometimes. When you over-eat, you have to stop trying to reinvigorate, and the reproductive system responds to most of it because, like the white blood cells, this is a young cell; they like to respond and rejuvenate. Hopefully, we have helped today, at least one couple, if not many. Hopefully, we can change their lives and help them grow their families.
Aumatma Simmons, ND, Fabine, MS
Thank you for being with us.
Joseph Antoun, MD, PhD, MPP
Thank you very much.
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