Full Transcript Introduction to Wy protocol 0:02 and why so many women fear hormone 0:02 and why so many women fear hormone therapy in the first place. If you've 0:04 therapy in the first place. If you've 0:04 therapy in the first place. If you've ever wondered whether rhythmic hormone 0:07 ever wondered whether rhythmic hormone 0:07 ever wondered whether rhythmic hormone therapy is revolutionary or risky, stay 0:09 therapy is revolutionary or risky, stay 0:09 therapy is revolutionary or risky, stay with me. You're about to get clarity 0:11 with me. You're about to get clarity 0:11 with me. You're about to get clarity that most women never receive from their 0:14 that most women never receive from their 0:14 that most women never receive from their doctors. 0:36 Hey everyone, Dr. Fred Bloom here. 0:36 Hey everyone, Dr. Fred Bloom here. Welcome back. If you're new to the 0:38 Welcome back. If you're new to the 0:38 Welcome back. If you're new to the channel, I'm an integrative and holistic 0:40 channel, I'm an integrative and holistic 0:40 channel, I'm an integrative and holistic physician helping people restore their 0:42 physician helping people restore their 0:42 physician helping people restore their vitality using natural, functional, and 0:46 vitality using natural, functional, and 0:46 vitality using natural, functional, and regenerative approaches without the 0:48 regenerative approaches without the 0:48 regenerative approaches without the guesswork. Today we're diving into one 0:51 guesswork. Today we're diving into one 0:51 guesswork. Today we're diving into one of the most misunderstood and most 0:53 of the most misunderstood and most 0:53 of the most misunderstood and most powerful topics in women's health. 0:55 powerful topics in women's health. 0:55 powerful topics in women's health. Rhythmic hormone dosing, also known as 0:57 Rhythmic hormone dosing, also known as 0:57 Rhythmic hormone dosing, also known as the WY protocol. We're going to explore 1:00 the WY protocol. We're going to explore 1:00 the WY protocol. We're going to explore what it is, why it exists, what makes it 1:03 what it is, why it exists, what makes it 1:04 what it is, why it exists, what makes it controversial, what the science and 1:06 controversial, what the science and 1:06 controversial, what the science and physiology suggest, what I've personally 1:09 physiology suggest, what I've personally 1:09 physiology suggest, what I've personally seen since offering it to patients since 1:11 seen since offering it to patients since 1:11 seen since offering it to patients since 2007, and why so many women fear hormone 1:15 2007, and why so many women fear hormone 1:15 2007, and why so many women fear hormone therapy in the first place. If you've 1:17 therapy in the first place. If you've 1:17 therapy in the first place. If you've ever wondered whether rhythmic hormone 1:19 ever wondered whether rhythmic hormone 1:19 ever wondered whether rhythmic hormone therapy is revolutionary or risky, stay 1:22 therapy is revolutionary or risky, stay 1:22 therapy is revolutionary or risky, stay with me. You're about to get clarity 1:24 with me. You're about to get clarity 1:24 with me. You're about to get clarity that most women never receive from their 1:26 that most women never receive from their 1:26 that most women never receive from their doctors. Don't forget to like, 1:28 doctors. Don't forget to like, 1:28 doctors. Don't forget to like, subscribe, and join my newsletter to 1:30 subscribe, and join my newsletter to 1:30 subscribe, and join my newsletter to stay connected. Most women who receive
Physiology of rhythm 1:32 stay connected. Most women who receive 1:32 stay connected. Most women who receive BHRT get static dosing, the same hormone 1:36 BHRT get static dosing, the same hormone 1:36 BHRT get static dosing, the same hormone dose every single day. Convenient? Yes. 1:41 dose every single day. Convenient? Yes. 1:41 dose every single day. Convenient? Yes. Physiological? Not even close. A healthy 1:45 Physiological? Not even close. A healthy 1:45 Physiological? Not even close. A healthy cycling woman doesn't produce a flat 1:48 cycling woman doesn't produce a flat 1:48 cycling woman doesn't produce a flat line of hormones. She produces a natural 1:51 line of hormones. She produces a natural 1:51 line of hormones. She produces a natural rise and fall, a rhythmic curve of 1:54 rise and fall, a rhythmic curve of 1:54 rise and fall, a rhythmic curve of estrogen and progesterone that shifts 1:57 estrogen and progesterone that shifts 1:57 estrogen and progesterone that shifts day by day. This rhythm matters from the 2:00 day by day. This rhythm matters from the 2:00 day by day. This rhythm matters from the body's perspective. Hormone timing, 2:03 body's perspective. Hormone timing, 2:03 body's perspective. Hormone timing, pulsatility, 2:05 pulsatility, 2:05 pulsatility, and receptor formation are just as 2:07 and receptor formation are just as 2:07 and receptor formation are just as important as the hormones themselves. A 2:10 important as the hormones themselves. A 2:10 important as the hormones themselves. A concept emphasized in the work and 2:12 concept emphasized in the work and 2:12 concept emphasized in the work and teachings of TS WY is that it's not just 2:16 teachings of TS WY is that it's not just 2:16 teachings of TS WY is that it's not just how much hormone you take, it's when and 2:20 how much hormone you take, it's when and 2:20 how much hormone you take, it's when and how you take it. And the more we look at 2:22 how you take it. And the more we look at 2:22 how you take it. And the more we look at physiology, the more we see how true 2:25 physiology, the more we see how true 2:25 physiology, the more we see how true this is. When this rhythm disappears in 2:27 this is. When this rhythm disappears in 2:27 this is. When this rhythm disappears in parameopause and menopause, symptoms 2:30 parameopause and menopause, symptoms 2:30 parameopause and menopause, symptoms appear. Hot flashes, insomnia, joint 2:33 appear. Hot flashes, insomnia, joint 2:33 appear. Hot flashes, insomnia, joint aches, lowered libido, thinning bones, 2:37 aches, lowered libido, thinning bones, 2:37 aches, lowered libido, thinning bones, brain fog, mood swings. The WY protocol 2:40 brain fog, mood swings. The WY protocol 2:40 brain fog, mood swings. The WY protocol was designed to mirror the biological 2:43 was designed to mirror the biological 2:43 was designed to mirror the biological rhythm of a youthful cycle using 2:46 rhythm of a youthful cycle using 2:46 rhythm of a youthful cycle using carefully timed standardized doses of 2:49 carefully timed standardized doses of 2:49 carefully timed standardized doses of transermal estradiol and progesterone. 2:52 transermal estradiol and progesterone. 2:52 transermal estradiol and progesterone. In my experience, restoring rhythm often 2:54 In my experience, restoring rhythm often 2:54 In my experience, restoring rhythm often restores a woman's sense of self. Before 2:57 restores a woman's sense of self. Before 2:57 restores a woman's sense of self. Before creating the protocol, TS Wy spent years 3:00 creating the protocol, TS Wy spent years 3:00 creating the protocol, TS Wy spent years studying endocrinology, aging, sleep 3:03 studying endocrinology, aging, sleep 3:03 studying endocrinology, aging, sleep biology, molecular biology, and the 3:06 biology, molecular biology, and the 3:06 biology, molecular biology, and the patterns of ovulation. She asked logical 3:08 patterns of ovulation. She asked logical 3:08 patterns of ovulation. She asked logical questions that most of the medical 3:10 questions that most of the medical 3:10 questions that most of the medical establishment never addressed. For 3:12 establishment never addressed. For 3:12 establishment never addressed. For example, all pregnant women have 3:14 example, all pregnant women have 3:14 example, all pregnant women have extremely high estrogen levels. So if 3:16 extremely high estrogen levels. So if 3:16 extremely high estrogen levels. So if estrogen were inherently deadly, 3:19 estrogen were inherently deadly, 3:19 estrogen were inherently deadly, humanity wouldn't exist. Her work 3:21 humanity wouldn't exist. Her work 3:21 humanity wouldn't exist. Her work emphasized the importance of pulsatile 3:23 emphasized the importance of pulsatile 3:23 emphasized the importance of pulsatile delivery, not static amplitude, not a 3:26 delivery, not static amplitude, not a 3:26 delivery, not static amplitude, not a one-sizefitsall dose receptor behavior, 3:30 one-sizefitsall dose receptor behavior, 3:30 one-sizefitsall dose receptor behavior, not just serum levels, daily variation, 3:33 not just serum levels, daily variation, 3:33 not just serum levels, daily variation, not hormonal monotony. This is why the 3:35 not hormonal monotony. This is why the 3:35 not hormonal monotony. This is why the protocol uses a dayby-day schedule 3:38 protocol uses a dayby-day schedule 3:38 protocol uses a dayby-day schedule because that's how the endocrine system 3:40 because that's how the endocrine system 3:40 because that's how the endocrine system naturally functions. Let's be honest,
Addressing hormone fears 3:43 naturally functions. Let's be honest, 3:43 naturally functions. Let's be honest, hormones scare people, doctors, too. 3:46 hormones scare people, doctors, too. 3:46 hormones scare people, doctors, too. This is largely because of 3:47 This is largely because of 3:47 This is largely because of misunderstandings from the early 2000s 3:51 misunderstandings from the early 2000s 3:51 misunderstandings from the early 2000s WHI, 3:52 WHI, 3:52 WHI, Women's Health Initiative study. The 3:54 Women's Health Initiative study. The 3:54 Women's Health Initiative study. The sound bite that stuck in the public mind 3:56 sound bite that stuck in the public mind 3:56 sound bite that stuck in the public mind was estrogen causes breast cancer. But 3:59 was estrogen causes breast cancer. But 3:59 was estrogen causes breast cancer. But when you look at the actual data and 4:01 when you look at the actual data and 4:01 when you look at the actual data and subsequent analyses, you understand that 4:04 subsequent analyses, you understand that 4:04 subsequent analyses, you understand that synthetic protestants were responsible 4:07 synthetic protestants were responsible 4:07 synthetic protestants were responsible for increased risk. Transermal estradile 4:11 for increased risk. Transermal estradile 4:11 for increased risk. Transermal estradile was not the villain. The formulation and 4:14 was not the villain. The formulation and 4:14 was not the villain. The formulation and route mattered. The WHI did not study 4:18 route mattered. The WHI did not study 4:18 route mattered. The WHI did not study rhythmic dosing and even conventional 4:20 rhythmic dosing and even conventional 4:20 rhythmic dosing and even conventional experts now acknowledge the complexity. 4:23 experts now acknowledge the complexity. 4:23 experts now acknowledge the complexity. One of the clearest concepts in Wley's 4:26 One of the clearest concepts in Wley's 4:26 One of the clearest concepts in Wley's work is oral progesterone can convert 4:29 work is oral progesterone can convert 4:29 work is oral progesterone can convert into neuroactive metabolites like GABA 4:32 into neuroactive metabolites like GABA 4:32 into neuroactive metabolites like GABA causing sedation but not necessarily 4:34 causing sedation but not necessarily 4:34 causing sedation but not necessarily giving therapeutic progesterone receptor 4:37 giving therapeutic progesterone receptor 4:37 giving therapeutic progesterone receptor activation. Static progesterone 4:39 activation. Static progesterone 4:39 activation. Static progesterone especially oral doses can even behave in 4:42 especially oral doses can even behave in 4:42 especially oral doses can even behave in gluccocorticoid like ways contributing 4:45 gluccocorticoid like ways contributing 4:45 gluccocorticoid like ways contributing to weight gain if not paired with robust 4:47 to weight gain if not paired with robust 4:47 to weight gain if not paired with robust estrogen receptor activation. So, what 4:50 estrogen receptor activation. So, what 4:50 estrogen receptor activation. So, what about cancer risk with rhythmic dosing? 4:52 about cancer risk with rhythmic dosing? 4:52 about cancer risk with rhythmic dosing? In Wley's long-term population of around 4:55 In Wley's long-term population of around 4:55 In Wley's long-term population of around 20,000 users, there were only a small 4:58 20,000 users, there were only a small 4:58 20,000 users, there were only a small handful of lobular breast cancers over 5:00 handful of lobular breast cancers over 5:00 handful of lobular breast cancers over more than 20 years. Statistically, 5:03 more than 20 years. Statistically, 5:03 more than 20 years. Statistically, that's comparable or in some cases lower 5:06 that's comparable or in some cases lower 5:06 that's comparable or in some cases lower than baseline risk. In my own practice,
Clinical benefits and myths 5:09 than baseline risk. In my own practice, 5:09 than baseline risk. In my own practice, most women on the protocol have done 5:11 most women on the protocol have done 5:11 most women on the protocol have done very well. Some have seen better bone 5:13 very well. Some have seen better bone 5:13 very well. Some have seen better bone health, improved mood and cognition, 5:16 health, improved mood and cognition, 5:16 health, improved mood and cognition, improved metabolic markers. And here's 5:19 improved metabolic markers. And here's 5:19 improved metabolic markers. And here's something every woman deserves to hear. 5:21 something every woman deserves to hear. 5:21 something every woman deserves to hear. Doing nothing is not risk-f free. Low 5:24 Doing nothing is not risk-f free. Low 5:24 Doing nothing is not risk-f free. Low estrogen and progesterone increase risk 5:27 estrogen and progesterone increase risk 5:27 estrogen and progesterone increase risk for osteoporosis, cardiovascular 5:29 for osteoporosis, cardiovascular 5:29 for osteoporosis, cardiovascular disease, insulin resistance, cognitive 5:32 disease, insulin resistance, cognitive 5:32 disease, insulin resistance, cognitive decline, depression, chronic pain, 5:35 decline, depression, chronic pain, 5:35 decline, depression, chronic pain, disrupted sleep. As Wy puts it, when you 5:39 disrupted sleep. As Wy puts it, when you 5:39 disrupted sleep. As Wy puts it, when you cease to be reproductive, the body 5:41 cease to be reproductive, the body 5:41 cease to be reproductive, the body starts to fall apart. While I would 5:43 starts to fall apart. While I would 5:43 starts to fall apart. While I would phrase it more gently, the principle is 5:46 phrase it more gently, the principle is 5:46 phrase it more gently, the principle is sound. Hormone loss accelerates aging. 5:49 sound. Hormone loss accelerates aging. 5:49 sound. Hormone loss accelerates aging. When arhythmic dosing is done correctly, 5:52 When arhythmic dosing is done correctly, 5:52 When arhythmic dosing is done correctly, many women report better sleep, restored 5:55 many women report better sleep, restored 5:55 many women report better sleep, restored libido, resolution of hot flashes, 5:58 libido, resolution of hot flashes, 5:58 libido, resolution of hot flashes, improved vaginal health, reduced joint 6:01 improved vaginal health, reduced joint 6:01 improved vaginal health, reduced joint pain, enhanced mood, clearer thinking, 6:05 pain, enhanced mood, clearer thinking, 6:05 pain, enhanced mood, clearer thinking, better metabolic control. Many women on 6:07 better metabolic control. Many women on 6:07 better metabolic control. Many women on the WY protocol have been using it for 6:09 the WY protocol have been using it for 6:09 the WY protocol have been using it for over 10 to 15 years, and they say they 6:12 over 10 to 15 years, and they say they 6:12 over 10 to 15 years, and they say they would never live without it. In my 6:15 would never live without it. In my 6:15 would never live without it. In my practice, I've seen this too, especially 6:17 practice, I've seen this too, especially 6:17 practice, I've seen this too, especially among women who didn't respond to static 6:19 among women who didn't respond to static 6:19 among women who didn't respond to static dosing, had persistent PMS- like 6:22 dosing, had persistent PMS- like 6:22 dosing, had persistent PMS- like symptoms even after menopause, were 6:24 symptoms even after menopause, were 6:24 symptoms even after menopause, were extremely sensitive to conventional 6:26 extremely sensitive to conventional 6:26 extremely sensitive to conventional progesterone therapies, needed more 6:28 progesterone therapies, needed more 6:28 progesterone therapies, needed more support for sleep and mood, wanted a 6:31 support for sleep and mood, wanted a 6:31 support for sleep and mood, wanted a more youthful metabolic profile, or 6:33 more youthful metabolic profile, or 6:33 more youthful metabolic profile, or wanted the closest possible mimic of 6:35 wanted the closest possible mimic of 6:36 wanted the closest possible mimic of natural physiology. I've also adapted 6:38 natural physiology. I've also adapted 6:38 natural physiology. I've also adapted rhythmic principles for men who have 6:40 rhythmic principles for men who have 6:40 rhythmic principles for men who have their own hormonal rhythms especially 6:43 their own hormonal rhythms especially 6:43 their own hormonal rhythms especially relating to sleep, testosterone and 6:45 relating to sleep, testosterone and 6:45 relating to sleep, testosterone and adrenal balance. This is one of the most 6:48 adrenal balance. This is one of the most 6:48 adrenal balance. This is one of the most common objections. I just want to do 6:51 common objections. I just want to do 6:51 common objections. I just want to do menopause naturally to which my response 6:54 menopause naturally to which my response 6:54 menopause naturally to which my response and wies is simply how is natural 6:56 and wies is simply how is natural 6:56 and wies is simply how is natural feeling for you. We need to acknowledge 6:59 feeling for you. We need to acknowledge 6:59 feeling for you. We need to acknowledge we don't live naturally. We don't sleep 7:02 we don't live naturally. We don't sleep 7:02 we don't live naturally. We don't sleep naturally. We don't eat naturally. We 7:06 naturally. We don't eat naturally. We 7:06 naturally. We don't eat naturally. We don't move naturally. We're surrounded 7:08 don't move naturally. We're surrounded 7:08 don't move naturally. We're surrounded by endocrine disruptors. Yet hormones, 7:12 by endocrine disruptors. Yet hormones, 7:12 by endocrine disruptors. Yet hormones, real biodidentical physiologic hormones 7:15 real biodidentical physiologic hormones 7:15 real biodidentical physiologic hormones are somehow considered unnatural. This 7:17 are somehow considered unnatural. This 7:17 are somehow considered unnatural. This double standard is one of the biggest 7:19 double standard is one of the biggest 7:19 double standard is one of the biggest barriers to women getting help. One of
Melatonin and circadian care 7:22 barriers to women getting help. One of 7:22 barriers to women getting help. One of the most fascinating insights from 7:23 the most fascinating insights from 7:23 the most fascinating insights from Wigh's work involves melatonin. She 7:26 Wigh's work involves melatonin. She 7:26 Wigh's work involves melatonin. She explains, "Melatonin creates the 7:28 explains, "Melatonin creates the 7:28 explains, "Melatonin creates the receptor for vitamin D, meaning you can 7:31 receptor for vitamin D, meaning you can 7:31 receptor for vitamin D, meaning you can take all the vitamin D you want, but if 7:34 take all the vitamin D you want, but if 7:34 take all the vitamin D you want, but if you don't sleep, your body may not be 7:36 you don't sleep, your body may not be 7:36 you don't sleep, your body may not be able to use it." She also explains why 7:39 able to use it." She also explains why 7:39 able to use it." She also explains why so many women wake up around 1 to 3:00 7:41 so many women wake up around 1 to 3:00 7:42 so many women wake up around 1 to 3:00 a.m. Without a strong nighttime 7:44 a.m. Without a strong nighttime 7:44 a.m. Without a strong nighttime melatonin surge, estrogen does not 7:47 melatonin surge, estrogen does not 7:47 melatonin surge, estrogen does not rebound properly overnight. In my 7:49 rebound properly overnight. In my 7:49 rebound properly overnight. In my practice, optimizing circadian rhythms, 7:52 practice, optimizing circadian rhythms, 7:52 practice, optimizing circadian rhythms, rhythmic hormones, melatonin, light 7:54 rhythmic hormones, melatonin, light 7:54 rhythmic hormones, melatonin, light exposure, and stress hormones often 7:57 exposure, and stress hormones often 7:57 exposure, and stress hormones often solves stubborn insomnia that women have 7:59 solves stubborn insomnia that women have 7:59 solves stubborn insomnia that women have struggled with for years. If you're
Actionable advice and closure 8:01 struggled with for years. If you're 8:01 struggled with for years. If you're considering hormone therapy, rhythmic or 8:04 considering hormone therapy, rhythmic or 8:04 considering hormone therapy, rhythmic or static, here's what I tell my patients. 8:07 static, here's what I tell my patients. 8:07 static, here's what I tell my patients. Get evaluated fully. Hormones interact 8:10 Get evaluated fully. Hormones interact 8:10 Get evaluated fully. Hormones interact with thyroid, cortisol, infections, 8:13 with thyroid, cortisol, infections, 8:13 with thyroid, cortisol, infections, toxins, and sleep. Understand your 8:15 toxins, and sleep. Understand your 8:15 toxins, and sleep. Understand your options. Static dosing is good. Rhythmic 8:18 options. Static dosing is good. Rhythmic 8:18 options. Static dosing is good. Rhythmic dosing is physiologic and better. Don't 8:21 dosing is physiologic and better. Don't 8:21 dosing is physiologic and better. Don't let fear guide decisions. Fear has kept 8:25 let fear guide decisions. Fear has kept 8:25 let fear guide decisions. Fear has kept too many women suffering unnecessarily. 8:28 too many women suffering unnecessarily. 8:28 too many women suffering unnecessarily. Aim for the most natural physiology 8:30 Aim for the most natural physiology 8:30 Aim for the most natural physiology possible. If restoring rhythm gives you 8:33 possible. If restoring rhythm gives you 8:33 possible. If restoring rhythm gives you your vitality back, it's worth 8:35 your vitality back, it's worth 8:35 your vitality back, it's worth exploring. Track your progress. Bone 8:38 exploring. Track your progress. Bone 8:38 exploring. Track your progress. Bone density, sleep, libido, cognition, 8:42 density, sleep, libido, cognition, 8:42 density, sleep, libido, cognition, metabolism, they all matter. Be 8:44 metabolism, they all matter. Be 8:44 metabolism, they all matter. Be personally involved. The women who do 8:46 personally involved. The women who do 8:46 personally involved. The women who do best are the ones who learn, ask 8:49 best are the ones who learn, ask 8:49 best are the ones who learn, ask questions, and stay engaged. Women 8:51 questions, and stay engaged. Women 8:51 questions, and stay engaged. Women deserve far better information than what 8:54 deserve far better information than what 8:54 deserve far better information than what they've been given. If you've been 8:55 they've been given. If you've been 8:55 they've been given. If you've been battling fatigue, brain fog, sleep 8:58 battling fatigue, brain fog, sleep 8:58 battling fatigue, brain fog, sleep issues, mood changes, hot flashes, 9:01 issues, mood changes, hot flashes, 9:01 issues, mood changes, hot flashes, weight gain, bone loss, or chronic pain, 9:04 weight gain, bone loss, or chronic pain, 9:04 weight gain, bone loss, or chronic pain, you don't have to accept it as just 9:06 you don't have to accept it as just 9:06 you don't have to accept it as just aging. You have options. and rhythmic 9:09 aging. You have options. and rhythmic 9:09 aging. You have options. and rhythmic hormone therapy is one of the most 9:11 hormone therapy is one of the most 9:11 hormone therapy is one of the most intriguing physiologic and potentially 9:15 intriguing physiologic and potentially 9:15 intriguing physiologic and potentially transformative options available. If you 9:17 transformative options available. If you 9:17 transformative options available. If you want help exploring this, my office is 9:19 want help exploring this, my office is 9:19 want help exploring this, my office is here for you. I'd love to hear from you. 9:21 here for you. I'd love to hear from you. 9:21 here for you. I'd love to hear from you. Have you tried hormone therapy? Did 9:23 Have you tried hormone therapy? Did 9:23 Have you tried hormone therapy? Did static dosing work for you or not so 9:25 static dosing work for you or not so 9:25 static dosing work for you or not so much? Does rhythmic dosing make 9:27 much? Does rhythmic dosing make 9:27 much? Does rhythmic dosing make intuitive sense to you? What questions 9:29 intuitive sense to you? What questions 9:29 intuitive sense to you? What questions do you still have? Drop your thoughts in 9:32 do you still have? Drop your thoughts in 9:32 do you still have? Drop your thoughts in the comments. I read every single one. 9:34 the comments. I read every single one. 9:34 the comments. I read every single one. If you found this valuable, like, 9:36 If you found this valuable, like, 9:36 If you found this valuable, like, subscribe, join my newsletter, and share 9:39 subscribe, join my newsletter, and share 9:39 subscribe, join my newsletter, and share this with someone who may need it. I'll 9:41 this with someone who may need it. I'll 9:41 this with someone who may need it. I'll see you in the next video.
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