Mycotoxins: Their Impact On Your Survival Systems

Isaac Eliaz, MD, MS, LAc

Thank you. Thank you for having me.

Ann Shippy, MD

This will be great. You have such an incredible background for our audience. You wrote a book called The Survival Paradox. I would love for you to give us an introduction to some of your incredible work that is a bestseller. Because I think it is relevant to us and our audience.

Isaac Eliaz, MD, MS, LAc

Yes. It is the book in many ways. It is the culmination of a few decades of studies and research in clinical work, and it presents a new paradigm that goes along with functional medicine. The paradox is that we are wired to survive. We are wired to stay alive at any cost. But the mechanisms of survival that are built within us are the same mechanisms that get us to suffer in life. It tends to be reactive, which gets us sick on an acute and chronic basis and eventually also shortens our lives. It relates to every area of medicine, and it relates particularly to the area of our topic today and to mycotoxins in chronic illness. It is because it is innate in us; it is built in us. Because it is built into us, it is automated through the sympathetic system. The sympathetic system responds with no control in a fraction of a second, as we all know.

Ann Shippy, MD

Or ready to run from that tiger. Without thinking about it, we just do it.

Isaac Eliaz, MD, MS, LAc

Exactly according to the survival mechanism, it is just a reflex; it does not go up to the brain. It goes either through fighting to survive, which equates to inflammation, or it goes by as running away or hiding in a field of light, where we shield ourselves and hide ourselves from the world. We create a microenvironment. This microenvironment, about which we will talk later today, is the ideal environment for mycotoxins. These are two very basic movements of the sympathetic system, which relate to inflammation and create a microenvironment with no oxygen. We are hiding there; it is sealed and prone to fibrosis, which causes organ degeneration. while we are in a sympathetic mode and we can take a deep breath, we can go out to nature, we can relax, and we shift back to parasympathetic. But if we stay more in the sympathetic system, the systems will change. when the body is under great stress for more than a short while, and I do not want to go to the question in the popular topic of stress adaptation and its benefits that, when we exercise hard or we go, people take ice baths. They do it consciously to get better when they get stressed because of a crisis; it is not conscious. It is very different, and people are confusing things and saying that stress is

Ann Shippy, MD

Not that you are making that distinction.

Isaac Eliaz, MD, MS, LAc

Because I talk to the oldest people, a scientist is great, but you have to be a clinician, and the logical stress that comes out of your stress is not good for us. What happens when we are stressed? Is there a weak spot in the body? Take the opportunity. When somebody is under stress, cancer and autoimmunity can get worse. People with Lyme disease know so well. You are under stress. This biology spoke; it wakes up the mycotoxins that drive this process. We want to understand this. The problem is that when it comes to the sympathetic and parasympathetic, we can shift in a few minutes. But when the biochemical system gets the signal that we need to survive it, we start a cascade of events. I have been talking about it for decades, but now it is so familiar to everybody. It is called the cytokine storm. It is a storm.

Ann Shippy, MD

Now everybody knows because I write.

Isaac Eliaz, MD, MS, LAc

About it now, all, exactly. Then suddenly, it leads to devastating effects. The triggers, from a biochemical point of view, of certain proteins allow the key one that I have researched for almost 30 years and made some of the key discoveries is a protein called Galectin-3. This protein has to change very little just to double itself for C-reactive protein to go up 100-fold or for interleukin-6 to go up 100-fold. We have a biochemical trigger that we are very interested in because there are simple solutions for how to block it. But we also want to see how we can change it from lifestyle and especially from mind-body medicine because our body is built to heal, and if we can change it, we will have a higher mental level, which is ideal in the study and practice. For many decades, we have had biochemicals, and they all give a complete picture. This is, in a nutshell, the survival paradox and how to approach it.

Ann Shippy, MD

Okay. For the people who want to understand what you are saying a little bit better, let us nerd out for just a minute and explain a little bit more about what Galectin-3 is, what triggers it, and what happens when it gets triggered. Just so it makes sense, there are all these things that we can talk about that we have some control over. But then there is this automatic response that happens that is so subtle but then so significant with these inflammation markers going up.

Isaac Eliaz, MD, MS, LAc

Galectin-3, and then in the book, I go through the whole story, explaining every organ system and disease and what to do about it in detail. But here, briefly, Galectin-3 is a carbohydrate-binding protein. We can look at it as the bus being the shuttle, okay? It is the Uber you are calling; something is happening, and you dial; I am in trouble. Galectin-3 gets excreted by immune cells by macrophages as well, but by many cells, but a lot of macrophages. It is also triggered by certain toxins. then it drives to the area of the problem and brings with it different ligands that can help us repair the injury. These are inflammatory ligands, certain growth factors, and cytokines, and then we start getting an inflammatory fibrotic area of Galectin-3, which could have spiked for a few minutes and gone back to normal. Nothing would happen. But even if it spikes for a few hours, it will end up. For example, I do a lot of work with sepsis, which is related in a certain way to the topic of toxins.

Ann Shippy, MD

People are saying sepsis is

Isaac Eliaz, MD, MS, LAc

Yes, it is an infection of the blood; if it gets bad in you in the ICU and you have kidney damage, you are talking about 60% mortality, or six zero. For this, you need very dramatic work. For example, I have been working on it for almost ten years, but I will only show it because it is moving to clinical trials. It is a biotech project. I am working on a filter to take out just Galectin-3, so Galectin-3 is going to be removed. You are going to take out the blood, separate the plasma and the fluid from the cell, take it out, and remove this Galectin-3. This Galectin-3 is present in nanograms in ten to the minus nine 0.0001.

Ann Shippy, MD

Gram amount.

Isaac Eliaz, MD, MS, LAc

By grams, the whole amount you pull out of the body is 100 micrograms. You cannot see it with your eyes. What we find is that when you induce sepsis in animals, even in large animals, similar to humans, Galectin-3 comes up first before interleukin-6. When we put it in a very unique model, well, when we put that in a poison pill model, when you put the animal into severe sepsis, you are going through sepsis in 45 minutes. While you are putting them in sepsis, you remove Galectin-3 for only 3 hours. The animal will never go into sepsis, while the regular animal will die and not get kidney damage. That is how dramatic it is in the ICU study that we’re just doing, and we will publish the second paper soon. kind of gives the exact data we are showing that what determines which of the patients who come into the ICU with sepsis in general, 40% mortality, the ones who will die will have a clear curve of Galectin-3 rising in the ICU while the ones who survived, regardless of how sick they came in, while the ones who go down will not die and interleukin-6 will go down in both patients who die and do not show.

Ann Shippy, MD

An important distinction, which I think is very important for our viewers, is that there may be somewhat of a genetic predisposition toward Galectin-3.

Isaac Eliaz, MD, MS, LAc

Very important.

Ann Shippy, MD

So for the sepsis patient, it is probably just part of that acute illness. But what we are talking about with the mold, mycotoxins, and other chronic diseases is just where it is, stays up, and maybe continues to ramp up over time.

Isaac Eliaz, MD, MS, LAc

Yes, it is very important. It is a genetic predisposition to how much Galectin-3 we excrete and how it is present. It can be presented in pentameter or monomer. When you are in the monomer, it can penetrate small areas more easily. Then, once it brings ligands, it creates a penta monomer, and when it gets a coating, it creates a coating lattice formation. This information is the backbone of the biofilm, which is where heavy metals, mycotoxins, and pesticides are going to hide in the gut. I was thinking about it, and I would love to hear your opinion about it. People who have mycotoxin and chronic illness and they are feeling better and they go are in an environment with a tiny amount of mycotoxin and they get immediate aggravation, especially those with

Ann Shippy, MD

upswing in the morning or grind.

Isaac Eliaz, MD, MS, LAc

It is not that they are overwhelmed by mycotoxins from the outside; it is just that mycotoxins are getting a signal: oops, we are home, we are in control. The whole world becomes our biosphere. Then we can start to know. That is what happened. I was thinking today, wow, it is an outside signal for the mycotoxin, the survivor’s signal. Well, with the party starting now, we are safe to raise our heads. It is fine. I would love to hear what you think about it. 

Ann Shippy, MD

Yes. I think that, especially when people are in the recovery stage, they are starting to improve. I do think that aspect of the immune system is hypervigilant. That is what I experienced myself. I would travel to a conference and have to change hotel rooms, sometimes multiple times, to find one that I could sleep in. Whereas now that my immune system is back in a good, regulated place and my toxin load is pretty low, it takes a lot for my body to scream at me. I just attended the Functional Medicine conference a couple of months ago, and it was in Orlando. It was extremely moldy, and I would suspect if I could have measured my Galectin-3, it would have been through the roof. I think I am probably one of those people from a genetic standpoint who can upregulate it because I started to get all kinds of symptoms that I had not had in years, which I was getting from just holding a cold glass of water. My body felt like I was hit by a truck. My brain was all foggy within a good learning environment for me, and it happened within 24 hours.

Isaac Eliaz, MD, MS, LAc

I spoke with a family member years ago at a Lyme conference. It is interesting. Now and years later, they can go into a moldy environment. It is not an issue anymore. There is a point where you will see that it is not an issue anymore, where your body regulates to the point where your immune system is no longer recognizing this as a danger or a problem. Receive the survival response. Your body said, My, I got to survive. Then it goes into this cytokine storm. At a certain point, the comfort zone changes. It is a big topic in medicine in general. It is that we can be on a more restricted diet, which often people do, but if we are healthy, we can eat more things and we can tolerate them. It is an issue of body tolerance. That is a big, whole topic to do.

Ann Shippy, MD

We could go so many different ways with this one. You are exactly right. There were times in my life when I was reactive to carrots and blueberries, and now I do not even think about those kinds of things. I think the thing for our audience is to let them know there is hope by addressing a lot of these things that you can down-regulate. What I want to do is have you dive a little bit more into your thoughts on somebody who knows that in this inflammatory state, Galectin-3 is highly elevated, and they are working through their whole recovery from the liquid toxin.

Isaac Eliaz, MD, MS, LAc

Maybe I will start by saying that you cannot rely on the level of Galectin-3 to decide if you need to address it. Because of genetics, you can still have low levels of Galectin-3 and still have a major issue with Galectin-3. It is driving the issue, especially with Lyme disease, with the mycotoxins, where the Galectin-3 may be sequestered inside the biofilm, inside the structure, and where we do not have an appropriate immune response. You will sometimes see patients with Lyme disease with very low Galectin-3, and you may have seen very low C-reactive protein. They respond, but TGF beta will skyrocket because they are driving fibrotic processes, and TGF beta is driven by Galectin-3. When they balance out, Galectin-3 will go up to a normal level of 7 to 8 to the lowest 4. You see in these patients, and then instead of being undetectable, it will become 0.1 or 0.2, and TGF beta will drop from 20,000, hopefully, to 3000, and then they will have balanced. There is going to be a fibrotic tendency and a hiding tendency, and this is very critical for people with chronic diseases. I will get you to the strategy. I am a practical guy if you think about it.

Ann Shippy, MD

Yes, go ahead.

Isaac Eliaz, MD, MS, LAc

If you think about mycotoxins, you just gave an example from Orlando. Mycotoxins do not thrive in dry, warm weather. They thrive in damp, especially in hot places, in places that hot places that are not ventilated, or in our basement, when it is humid and not ventilated. When you have areas in the body with a microenvironment where the cell metabolism is also changing, it changes. Then it allows mycotoxins and fungus to thrive. It is an anaerobic environment. What happens is that in this environment, the cell has to survive without oxygen. A lot of it is driven by Galectin-3 and by this lattice formation. Then what happens? Galectin-3 will block insulin receptors in the cell and get a signal; AMPK gets blocked. What efficiently produces ATP in the cell gets this, gets a signal—my, I am choking, I do not have oxygen. Then the proxy-inducing factor goes up. I am describing them now. You can visualize it inside the cell, which is, again, classic for mycotoxin, for chronic disease.

Ann Shippy, MD

Mitochondrial listening might occur. That is mitochondrial dysfunction. I love that you are at the cellular level, explaining what is happening.

Isaac Eliaz, MD, MS, LAc

Of course, then the mitochondria get blocked, and the cell goes into crisis. In an anaerobic glycolysis mode and aerobic glycolysis, there is more of a cancer effect; we produce 100 times more energy because we are in crisis, but we produce it at 5 to 6% efficiency, which means we are producing 2000 times more glucose, with more lactic acid and all the byproducts. These byproducts create more acidity and less oxygen, and the mycotoxins are jumping up and down. We are in the hall. It is more damp and sticky. That is what happens. We need to change the environment. The way to do it is to peel off these pockets of mycotoxins. The problem is that many patients know that when they use binders, they get aggravation. Why do they get aggravated? Well, if you open all the drawers where you shuffle all the stuff you do not want and throw it on the kitchen floor, it is going to be messy. It creates an inflammatory side to this kind of response, just like what happened to you in Orlando.

Ann Shippy, MD

Right.

Isaac Eliaz, MD, MS, LAc

When we blocked Galectin-3, it was modified; it was baked in. We picked the soil, which I developed almost 30 years ago and no longer have any financial interest in. I am talking to the researcher when we block it. Motivation to respect him is a phenomenal binder, but it regulates the inflammatory response. What you hear with so many mycotoxins is that I tried everything, and I modified it accordingly, and it changed my life. Why? Because it downregulated the inflammatory response. It allowed you to be in a place where, for example, in Orlando, you do not react while it is removing the mycotoxins. That is the fundamental movement in this, you can use anything else, whatever you are using.

Ann Shippy, MD

As for me, I just have a balance through clinical practice, and if I start with the modified aspect, everybody does better. But now you explain the science behind why that is the most gentle and productive way when we get to that part where we want to start removing the toxins.

Isaac Eliaz, MD, MS, LAc

It is very important because the defense it was picking is published to remove heavy metals like lead, mercury, arginine, cadmium, and uranium. You have the heavy metals that are driving, and the anaerobic, candida, and, I mean, mycotoxins that come from somewhere. It dries them down. You do not get the methylation of mercury anymore; you do not get it going into the brain and causing a fog. We can isolate mycotoxins in a country where each of us has that one pound of glyphosate being sprayed every year, no matter where you are. If you are in a beautiful resort in Orlando next to the golf course, you are being sprayed with glyphosate every day on the course, and you breathe it in; it goes into your food, and then suddenly it happens and people do not know what life with it is. It is the most common pesticide used. It is a recognized carcinogen, but it creates havoc on the gut lining. It creates inflammation in the gut lining. It triggers issues with mycotoxin. It works synergistically with mycotoxin. It disrupts the absorption of nutrients and allows mycotoxins to be absorbed systemically. That is an example. As part of this strategy, you also have to remove a pesticide, which I have come to recognize as having about three uses as well. Something is missing in my protocol, and we all, at least, were trained by Big Agra that there is nothing we can do. I mean, no matter what we do, it is going to be a little bit of pesticide. Okay. That safely. Well, I have never heard that poison can be safe in any dosage, so I made a point.

Ann Shippy, MD

Since they’re so synergistic, not one person equals two. It is one plus one, 300, or a thousand.

Isaac Eliaz, MD, MS, LAc

Exactly. Just so, and you can see, of course, the effect on the brain because glyphosate is very similar to glycine. It can exchange with it instead of having a natural protective neurotransmitter from the smallest amino acid, glycine, and you get an excited substance. It activates glial cells. Galectin-3 also activates glial cells; heavy metals activate glial cells, and then you get neuroinflammation. then it is not only the neuroinflammation that makes the brain inflamed. Of course, I am sure you had people interviewed about the brain-gut connection. I would not talk about it too much. Is it when the brain gets insulin, the signaling to the body changes everywhere, and then you get a hormonal imbalance? All of this started with a disruption to the gut lining that was driven by the chronic predisposition to mycotoxin and, hence, by glyphosate. Then you get autoimmunity that is driven, and then you live with it. The body is trying to get rid of this with the kidneys. We saw a dramatic increase in chronic kidney disease. Then, of course, people are not aware of 17% of the population.

When you address mycotoxins, you look at it as one thing: you have to address pesticides, you have to address heavy metals, you have to address your lifestyle, and you have to follow the functional route. Within all of this, you have to look at the mindset that helps mycotoxins. I will talk to you about it in a moment, but I want to talk about what happens if it does not work. Often, there are cases where it does not work. Then you have to revert to more dramatic treatments. the most dramatic treatment that is expensive. Unfortunately, it is considered a disruptor on a global level. This is what I do research on in terms of therapeutic offerings.

Ann Shippy, MD

I am so glad you mentioned this because that has been an area that I have not personally explored in my practice, but it keeps coming up, and what I am learning about it is that I want to be able to offer that to patients.

Isaac Eliaz, MD, MS, LAc

It is a very unique treatment. I was the first one to offer it in this country for non-elevated lipoprotein and LDL, and it is different from people who do it now. People do something called EBOO with the ozone in their blood. It is not the same. EBOO is not there if there is confusion.

Ann Shippy, MD

So the plasma apheresis too,

Isaac Eliaz, MD, MS, LAc

 Yes. Well, this is plasma exchange. In plasma.

Ann Shippy, MD

Exchange.

Isaac Eliaz, MD, MS, LAc

It is a tough procedure because you are also removing protein. Then it is usually done in a hospital environment. It is, and it is intense. It is a risky treatment. A Therapeutic Apheresis is extremely safe. Not one person in the history of races died from it.

Ann Shippy, MD

It is a good sign. 

Isaac Eliaz, MD, MS, LAc

It is a good sign for 30 years all over the world. What happens is that if you take the blood and selectively remove things that are not good for you, what is so interesting is that the filters that remove LDL are a bit oxidized lipids. This is where the mycotoxins are sitting. Sticky, non-sticky environment. We have therapeutic apheresis, and we have ways to do certain IVs during the process to enhance them. You get people who suddenly follow up with the different labs, and suddenly they do not have mycotoxins. It is remarkable. For certain people, it is a game-changer very quickly. For certain people with a detox, the pathways are not good, and they have a huge load. It takes multiple treatments, but often that is what you need for the other treatments to respond.

Ann Shippy, MD

Well, I think sometimes people, so many pathways are jammed with these toxins—proteins not working cell membranes and not healthy mitochondria poison in them. It can be so hard to just get their head above water and get some of these functions, the processes, and the body working together and getting the inflammation down. This looks like a great thing for people to think about when they’re just compromised and need that extra boost to get their pathways working again.

Isaac Eliaz, MD, MS, LAc

This is exactly the one thing that determines whether or not I will recommend certain people. I will say you just have to do this. We just wanted to do this. The ones we know of are genetically elevated. I know where there is a lot of oxidized LDL because, when you have this in the big round, it is not going to work. After all, when you have a lot of lipoprotein-A, which is a certain lipid in simple language that affects oxidation of the cell, it is called the silent killer if the cell is not getting oxygen. It was very popular in integrative medicine in the nineties, when it was discovered, and people were taking heparin for it. When you have something that does not allow oxygen to come to the cell anyway, mycotoxins are going to thrive. The real issue can be that you have elevated lipoprotein-A. Nobody is checked, so dietary strategies and supplements can help, but they are very limited because they are genetic. The one thing that makes things complicated for your work is that COVID has shifted this for the worse because for many COVID patients, even with very light disease and many people who had issues with the vaccine, it is the same package that there is reactivity of the lipid in the vascular and the calculation system with a rise in lipoprotein-A and a rise in oxidized lipids. That is, it is going to change medicine; unfortunately, it is going to shorten the lives of many, many people.

Ann Shippy, MD

We are talking solutions here. I think that is just changing the whole way that we think about cholesterol, and we think people either think of it as just something genetic or lifestyle. But what we know is that it is just part of the body’s response to what the environment is like. There are toxins to deal with, or there is some kind of repair process that needs to be happening. The body is regulated. You can see people with 300 or higher cholesterol who have no cardiovascular disease. Yet other people are walking time bombs in their forties.

Isaac Eliaz, MD, MS, LAc

Yes. One very often is lipoprotein-A, what is finally being done is that, as I am talking, I have taken lipoprotein since 1993 on every patient, it is early for me, but people are looking at the fractionation of lipids. It can have normal lipids in us, so it is oxidative, and if you have tiny particles, you are going to be in trouble. If you have a cholesterol level of 250 and your LDL is 130 and your cholesterol is all in the green and normal range, all your particles, you are not going to have a problem in cardiovascular. Of course, in orthodox or regular medicine, it all goes by standards—double-blind clinical trials. The individual does not have a place in this model.

Ann Shippy, MD

I just think that the regular cholesterol panels have the five readings.

Isaac Eliaz, MD, MS, LAc

The waste of time

Ann Shippy, MD

It should not be done because

Isaac Eliaz, MD, MS, LAc

I agree. But there are certain countries in the world where they are working diligently to get the differentiation of the fractionation and people are treated just based on their cholesterol class. It is a very big topic. I love it. We are going a little bit beyond, but for example, do you give a statin drug to somebody who has an elevated level of cholesterol?

Ann Shippy, MD

Well, we want to figure out what is causing it.

Isaac Eliaz, MD, MS, LAc

The time that you should, the time you should not. You look at the metabolism, and you say, What’s happening to them, and what, if any, is happening to lipoprotein-A? But with mycotoxins, they are almost the canary in the mine. When something is wrong in the mine and there is no oxygen coming, they are going to scream. That is where our mind response comes from because many people, such as mycotoxins, especially people with chronic mycotoxins with muscle activation, use a new popular term, which is valid, but it also labels people with a condition that is contrary to the concept of function. Function means change. When things move, everything can change, which means it is a static environment. When things get stuck, they get moldy and sticky. One of the issues with this group of patients, and I know from my journey, from my health, and from how I have recovered, is that when they get a symptom that relates to mycotoxins or muscle activation even more, it triggers in their minds the whole cascade of, Now this is going to come. They put themselves on this road on the Titan, and they are going to do this in survival protection contraction mode, which is exactly what the mycotoxins want us to do.

This way of working with the mind and using tools for meditation is so important. That is the key—the most important component of my work and my training. Again, it is beyond this interview, but it is where we shift the way our mind functions. We move from the head—from the ego-driven reactivity, which creates inflammation—to the open heart, which is all about flow. In the head, we are supposed to stop and analyze. In our hearts, the moment it stops, we are dead. The art is about flow and where the heart flows. Not only about the spiritual aspect today, because we do not have enough time when the heart flows into oxygen everywhere and the vascular system relaxes and the tension goes down in the neurotransmitter of tension and stress go down, and then the gut lining relaxes and the whole system changes, and then inflammation goes down, that would you experience in your healing. That is part of the journey. The journey of mycotoxin is addressing not just a few points but also our response and our anticipation. Very important. People must know what an allergic response is. It is an immune response when it is not supposed to be there. It is being hyper-vigilant. In this sense, it is somebody, the Chinese; the image of this ancient is somebody sitting in their house, ten days away, somebody is coming to their home. They may come their way or they may not, and they are already worried and stressed. When we are in distress, this is going to react to it. I know I am going to react to even 0.1 gram of my infected perspective. Guess what? I reacted to it.

Ann Shippy, MD

Of course, our brains too.

Isaac Eliaz, MD, MS, LAc

Obviously. We have to give ourselves the opportunity in this space and the recognition that we can heal. When we connect to this, what I call open heart medicine, anything and everything is possible. I love using the phrase, not everybody will be a miracle, but anyone can be a miracle because anything is changeable and everything is changeable. That is the hallmark of functional medicine. It is a function. The results can change.

Ann Shippy, MD

I love the way you have articulated this message because if anybody has one message to take away from that, it is inspiration and how it can heal. You just nailed it. That is so beautiful. I would love to spend a minute on the practical side of using modified Citrus Pectin, things to look for anything because I can imagine people listening; they are, okay, this is going to help me in so many different ways. I want to get started. What would you recommend?

Isaac Eliaz, MD, MS, LAc

You have to build up to the full dose of 15 grams of this one, and it is important when used. What if it was effective to use the solid that is the most effective to respect that there has been research in not only over 80 published papers, including a lot of papers about biofilm and microbiome with the USDA? If you start with one scoop a day or six capsules, it is better to use powder. The five grams, if you start with five grams, most people will tolerate it well. If you have a little bit of bloating or a little bit of gas, it is normal; it is a fiber; the pH is balanced with sodium and potassium; and the ratio of potassium to sodium is a healthy 4 to 1 ratio. It takes time. There is a

Ann Shippy, MD

If you’re bloating, just deal with it. You’ve got a lot to

Isaac Eliaz, MD, MS, LAc

Go along with it, and then go up to the full dose. You can take a scoop in half, seven grams twice a day, or if you have time, you can take five grams three times a day, and it is fine to take it only ten or 15 minutes before eating. You can take it with other supplements. It is fine.

Ann Shippy, MD

You can take it with other supplements.

Isaac Eliaz, MD, MS, LAc

Then I created the restriction in 1995, and then we did studies and showed it does not affect the absorption of minerals. It removes heavy metals. It is not an issue.

Ann Shippy, MD

We do not have to, and you do not have to worry about pulling out too many metals.

Isaac Eliaz, MD, MS, LAc

No, no, because it does not pull them from the tissue; you pull them from the circulation, and then, through a gradient, they will go down and then.

Ann Shippy, MD

It is best to go ahead and finish.

Isaac Eliaz, MD, MS, LAc

No, please go ahead.

Ann Shippy, MD

It sounds like it pulls out the mycotoxins, the heavy metals, and the pesticides. Is there anything that does not take

Isaac Eliaz, MD, MS, LAc

Well, it pulls out heavy metals, breaks the biofilm, and pulls out some of the mycotoxins. But because you can use it, you can add other binders if you want with it, but you often do not.

Ann Shippy, MD

You can take it to other binders at the same time.

Isaac Eliaz, MD, MS, LAc

Yes, definitely. But you often do not need to. You will be surprised. In the United States, there are quite a few large Lyme and Mycotoxins clinics. Automatically, every patient is put on what effect it is taking because of the benefits and because you look at the effect on longevity at a lower level of latency. That is one thing. then you want to get to the 15 grams a day, and then some people will find that afterward, it can keep the benefit in a low dose. You can go down, but give yourself a chance at 15 grams if you take your

Ann Shippy, MD

How long do you usually see?

Isaac Eliaz, MD, MS, LAc

That is sometimes the case for people who have tended for a long time. People with cancer for life. I tried to take 15 grams when I did not, and they skipped my evening dose. I see the difference may be negligible when it would not be as low, definitely because it collectively drives diabetes. It is the same mechanism. Right, the same mitochondrial issue. But then, if you are younger, if you have a good baseline, and if you are eating well, yes, you can go down. But in my opinion, it is the most important supplement one can take because it does something that nothing else can do. The research supports it, and it is synergistic. You can see it in cancer with chemotherapy and radiation. Why? Because it allows anything we want to do to get to the target tissue in a better way. That is one part. Then you have to address pesticides and negatively charged fluoride, chloride, and bromide. while you do deliver nutrients to the body, and this is where I developed GlyphoDetox, a unique product that is focused on the removal of glyphosate in pesticides,  specifically. We have not finished our clinical trial, so we need a few more cases to show a clear statistical difference. But there is a very dramatic difference. We know we have something that is pulling out glyphosate, which is a big deal. It is probably the first time there will be a supplement documented specifically to pull out glyphosate.

Ann Shippy, MD

This is already available.

Isaac Eliaz, MD, MS, LAc

Yes, of course. It is a unique product because it includes regular pectin, so it does not get absorbed systemically, and it has a greater affinity for fat-soluble toxins. It includes alginate, which is similar but has a little bit of a different profile. Both alginate and pectin are considered swamp cleaners in the environmental industry. Then it includes kelp because kelp is a remarkable substance. Kelp in seaweed has alginate. Those are rich in organic iodine and minerals, nutrients, and proteins. You are getting it on nourishment. then it has fulvic acid from shilajit. Fulvic acid is an amazing agent that is documented to bind and it balances the gut lining, but it also reduces neuroinflammation and delivers all the microbes. All the trace elements are present.

Ann Shippy, MD

For our listeners, I just want to say that I do a ton of testing on my patients to look at their toxin levels at their best. Pretty much everybody that has high mycotoxins or has mold exposure has high glyphosate, heavy metals, and many other toxins. Having this kind of approach where there are multiple ways of throwing out those toxins is so important; nobody’s immune from glyphosate. Everybody has.

Isaac Eliaz, MD, MS, LAc

Exactly. I have yet to see one patient with the urine test, which has no glyphosate. Everybody is in even a little bit, and then there is glycine, so it helps you find production. It exchanges with glyphosate, which helps the brain. This combination is the winning combination for mycotoxins, it is the rescue kit on top of it. Then, you do everything else.

Ann Shippy, MD

I have a couple of supplements that are on what I call my desert island line. I live without it. I have an airdrop business. Phosphatidylcholine, because I am a little down, and now I am adding this.

Isaac Eliaz, MD, MS, LAc

Exactly. Interesting. Phosphatidylcholine and glutathione are two things I use during my apheresis process. I am exchanging, and afterward, for whatever I did not catch because my apheresis changes, which is oxidized and positively charged ions. I am using phosphatidylcholine; I am exchanging fat-soluble toxins on the membrane. Phosphatidylcholine is fat soluble, and the filter takes it out. That’s why I say it is so dramatic for mycotoxin patients because if our bodies are compromised, we are getting a filter to do the work for us for a few hours. I am fortunate to be able to see what is in people’s blood; no one else is, because I am seeing something in the bag. I can see that I can diagnose people just by looking at what comes out of the bag. It is surprising to the mycotoxin patients that they will be the ones where it is supposed to change color but not have any sticky stuff, and you get clumps of sticky stuff. Coming up, clumps of growth factors, clumps of fibrinogen in clumps of mycotoxin, and an oxidized lipid are coming together. You can see that what is happening in the body and what the patient would often feel is,  Wow. I can think sometime during the treatment and know shortly after.

Ann Shippy, MD

Treatments people usually need to do

Isaac Eliaz, MD, MS, LAc

For mycotoxins, I always say not to listen to them because what happens when you clean the blood one time is that the tissues can let go of them. If you do not, people can get worse.

Ann Shippy, MD

Then it is so important to do these things as maintenance.

Isaac Eliaz, MD, MS, LAc

Right.

Ann Shippy, MD

Back in that state again.

Isaac Eliaz, MD, MS, LAc

People have mycotoxins; these will be maintained even once a year or twice a year. Then they prevent the need for crisis and intense therapy for four weeks. Yes.

Ann Shippy, MD

That is great. One other question on the practical side of things. Are there labs that you should do to monitor your progress with things like TGF beta? Do you have some personality?

Isaac Eliaz, MD, MS, LAc

TGF Beta, LabCorp is very reliable because of that research, and you have been in for between 214 and 217. I treated hundreds of patients. They are the

Ann Shippy, MD

It sounds like an Encyclopedia. This is so fun.

Isaac Eliaz, MD, MS, LAc

Yes, so they are very old; they used to be a lab THD, I do not know if you remember, but Total Health Diagnostics, went out of business. They had great panels. for VEGF, plasma node with G.F. serum because it is affected by platelets, and then I will do LabCorp for Agent K for natural killer cells. We want to see where the immune system is. The interesting thing about the different urine tests for mycotoxins is that they are a little bit better for mycotoxins. Nobody has taken the time to study. What does it mean? Is it one week? Is it long-term or what? What was excreted in the last 24 hours? These are very successful. But I was challenged because I took a different road. They need to put money into research. You need to tell us what it means. For me, it is more documented when they do a mycotoxin test in different labs and they see that it is elevated. It tells me that there is an issue, and then I will follow up just to hopefully see if there is a change. But often, you will see that it does not directly reflect how the patient is doing. The clinical picture is very, very important. Eventually, we treat the person we do not know with the lab, but the lab becomes a light signal to us. For example, if your Galectin-3 is even above 14 or 15 or about 12, if you have mycotoxins, it is already elevated.

Now the standard will say normal under 17.8, or sometimes 22, even though initially the approval was for a patient with congestive heart failure. Most of them have kidney problems. They excrete Galectin-3: The standards are higher and above 17. 8.8 is a dime in a much greater percentage than below. But now, with a new automated platform—I mean, being probably the most experienced person in watching Galectin-3 in patients—anything ten, 11, or nine is in our normal range. Because I do this part of my research, I get plasma from multiple people who will give blood or donate, and I check plasma levels because I need it for my research about depletion. Most of them are around 6 to 8. That is, you would never get 6 to 8 with the manual if it were 10 to 12 years ago. But if your Galectin-3 is over 17.8 and you have an illness, you will need 20 grams of what if I from strict because you get more Galectin-3 to remove it. Simple equation of blocking blood, and you will see that the inflammation gets better. It is not more difficult to remove Galectin-3; it blocks its place. Where it binds, the inflammation is reduced. Galectin-3 is the way to go.

Ann Shippy, MD

Careful. Look at that. the details of what is happening on a cellular level. It makes the clinical so powerful at that level of research that you have done on this.

Isaac Eliaz, MD, MS, LAc

Yes, it does help. 

Ann Shippy, MD

Yes. I am curious and make up my mind about so many things. I am just so enjoying your brilliance here. The apheresis does not take out some of the collecting.

Isaac Eliaz, MD, MS, LAc

Yes, it does. It does not use this filter. This filter will remove 100% of what goes through the blood. That is what you need. That is why I am testing it for sepsis and emergencies. But on a chronic basis, operations will remove about 20–25% or so. It will be removed.

Ann Shippy, MD

It is a filter that you use with a person’s,

Isaac Eliaz, MD, MS, LAc

The Galectin-3 filter is in development. When you go through a regulatory process, you need to raise tens of millions of dollars and get these safety studies. But there is a reason for it. It has to be safe. I know that even if I am it, especially if you do something new, it takes more time. This idea is a new invention. But there is a reason for the regulatory system. There is an element of protection when someone is abused. Sometimes it is a different story. However, the regular filter that is now used is more for removing LDL and lipoprotein-A. Yes, this also takes some Galectin-3, but it will take any; it takes all the oxidized LDL that comes through. Eventually, you will filter enough plasma; it will take 80% because it gets diluted in the blood; it will remove 80% of lipoprotein-A; and it will reduce the heavy metals. It will then reduce mycotoxins very dramatically. One of the reasons for doing two treatments is that in the second treatment, there is much less cholesterol in the blood. You did not come back. The filter has more room to focus on the mycotoxins on the other sticky stick, and that is why you would think, Wow, the blood is going to be clean on the second if I have less in my bag. Usually, you have 2 to 3 times more in the bag because the body is now letting go and collecting it.

Ann Shippy, MD

We have covered so much at such a detailed level, and we are so grateful to you.

Isaac Eliaz, MD, MS, LAc

I might find that volume.

Ann Shippy, MD

This is great. Yes. I think it is so important to know not just what to do but why it works. It’s to me that gives hope, and people are using terms that they have not heard before that do not necessarily make sense. I think it is reassuring that there is a lot of detailed science behind it. Is there anything else for people to help them recover from—a toxin, a chronic illness as it relates to cancer or autoimmune diseases, diabetes—all these things that are being caused that we want our listeners to know about?

Isaac Eliaz, MD, MS, LAc

I think it is very basic and difficult to keep all the time. We had to stay away from refined sugars and anything that spikes insulin. One of the secrets to doing it is drinking enough water, and we are all chronically dehydrated. You will be surprised. We have to drink about three-quarters of water every day, and very few people do. As simple as drinking two glasses of water when you wake up and two glasses of water before every meal, and then remember to drink two glasses of water twice in the day, before bedtime if it is okay, or after dinner enough. You do not want to dilute the digestive process. The moment you hydrate, the sense of hunger goes down, leptin goes up, insulin goes down, and what happens? The only way to satisfy your hunger for insulin and then demand dopamine is with refined sugars.

It also has to be in a way that we do not feel deprived. It is important, and doing diets that deprive us is not a good idea. The other important thing is the gut’s need for repair time and relaxation time. In this sense, intermittent fasting is a no-brainer. If there is one thing in the dietary regimen we can agree on, it is the benefits of intermittent fasting. We give a break, we give autophagy a chance, and when the cell gets clean, it can recalibrate itself, which is especially critical for mycotoxin patients because it still feels more refreshed. It took a good nap. It is not in crisis, and once there is more oxygen coming to the cells, mycotoxins are losing the battle. They cannot survive. They simply cannot survive. they do not replace. They can get cleaned up more easily, and they can accumulate. then, over time, we get better.

Ann Shippy, MD

I love that we are coming to the end of something so simple to implement but so effective.

Isaac Eliaz, MD, MS, LAc

Totally.

Ann Shippy, MD

I love it. If you would share how to find the Pectasol and then how to find you,

Isaac Eliaz, MD, MS, LAc

Yes. People can go to dreliaz.corg. D-R-E-L-I-A-Z. That all is. Of course, they can search and pick the solids. It is made by a company called Econugenics. I recommend the survival products. Not because I wrote it, but because it offers something for patients and health providers. It offers a different way of understanding how our bodies function and how our lives function. It goes through a philosophical journey, a scientific journey, and a practical journey. Then there are three chapters about solution detoxification, where I give a little bit of a broader understanding of what it means. Healing your scars of survival—genetic and epigenetic—and then freeing the survivor products—how they are mind—then, once you go through this journey, you will have about 80 pages of protocols at the end of the book. The book is a journey. It is tools, and then the details are there. You have details. This is a detox diet, and this is decent to do for that. Yes, but it is not a recipe book. It is a book about a journey. We shift to survival because when we move away from survival when there is something that comes to us and we all fall into it, but we all have the capacity not to fall into it, we do not respond with anger or fear, but we accept and we open our hearts. It changes our lives.

Now, this is not cliche because every cell in the body wants to get nourishment and throws away toxins. It wants to survive. The only organ in the body that we open our arms to takes the blood that everybody lets go of and does not want, which is the heart. The heart has to take all the dirty blood to connect with the universe, change the quality, and give blood without discrimination. In the old days, it was given without discrimination. The heart of survival is to give. To do this, it has to take the dirty blood. No dirty blood comes. It can be alive. We can transform what our cells consider toxins—our suffering on an emotional, spiritual, and physical toxin level—and use it as a substrate, which is the wood for the fire of nourishment in the heart. Once it gives blood, it relaxes, and only then does it nourish itself through the coronary arteries. But there, closest to the heart, because the heart nourishes itself to nourish others and is part of nourishing others, and self-love is part of loving others. that is important in healing. Do not be hard on yourself. It has not helped one person ever and will not help anybody. We all have the capacity for this. We all fall. I fall, and you, for everybody, fall into this. But we all can just open the closure, the contraction, which allows mycotoxins to thrive.

That is our genetics, our epigenetics, and our trauma. It is not who we are. We are just love because that is how we are wired. That’s why every spiritual tradition is the heart and center of the mind, or consciousness, which knows the divine within us. Every cell has this quality, and that is why anything and everything is possible. That is why, everybody, it can be a miracle the moment we connect to it. It is. Wow. That is the goal. That is the ultimate medicine. That is what I’m interested in. What I teach I have taught for many years, mainly in Israel, and I am going to start teaching, I am going to offer a free Zoom. Seven days and I am going to take people, even though I know in every day, probably in January of 24, and take them through a simple process so they can have these tools, and then start teaching face-to-face retreats, because it is amazing the transformation that happens, especially for patients with mycotoxins, autoimmunity, and chronic disease, because they just peel off. We all can do so.

Ann Shippy, MD

I have goosebumps there. In addition to being a brilliant physician and scientist, you have such a beautiful heart, and your heart has as much wisdom as your brain, which is quite phenomenal.

Isaac Eliaz, MD, MS, LAc

Thank you.

Ann Shippy, MD

I just love speaking with you, and I look forward to more times.

Isaac Eliaz, MD, MS, LAc

Absolutely. Take care. Have a great day.