Full Transcript Introduction to Prostate Enlargement 0:00 Do you know the real reasons why you have prostate enlargement? 0:03 So many men have urinary symptoms. 0:05 I keep them up at night. 0:06 Keep them going to the bathroom throughout the day. 0:09 And they're not addressing the root causes of why they have prostate enlargment. 0:13 In this video, I'm going walk you through the hormonal connection, the connection that a lot of doctors don't treat as to why men. 0:20 Have prostate and enlargement symptoms and why dressing the hormone issues can really help you with your enlarged prostate. 0:27 I'm Dr. 0:28 Mark Stengler. 0:28 I've been practicing integrative medicine for 30 years, and I have seen a lot of men with prostate problems. 0:34 Matter of fact, I wrote a book on the subject, which has done very well, where I outline in more detail what's going on with prostrate problems and how 0:42 to best help them integratively. 0:44 But in this video, i'm going to give you the key information you need to know and to address this hormone imbalance that's causing so many prostate problem. 0:54 Welcome to Health Breakthroughs with Dr. 0:55 Stengler. 0:56 I'm Dr Mark Stegler and each episode we cut through the noise to bring you practical, science-backed insights for more energy, 1:03 better health and a life that feels like yours again. 1:10 Benign Prostatic Hyperplasia known as BPH is an age-associated condition that involves enlargement of the prostate gland. 1:17 Now, this common condition affects approximately 50% of men between the ages of 51 and 60, but it becomes increasingly common as men age with 90% men at 1:28 age 85 having this condition. 1:30 Basically, the older that you get, more likely you're going to have prostate enlargement, a condition generally more severe and aggressive in African-American men. 1:40 Now the following urinary symptoms indicate that, you may have enlarged prostate or BPH.
BPH Symptoms and Conventional Treatment Risks 1:45 You could have incomplete emptying of your bladder. 1:48 Your bladder fills full even after voiding urine. 1:51 Increased frequency, the need to urinate often, every hour or two in some cases. 1:57 Intermittency, then need stop and start several times while urinating. 2:00 You can have a sense of urgency, a sensation of needing to Urinate right away. 2:06 you may have weak stream, weak or feeble urinary stream. 2:10 Straining or the Need to push or strain to start urine flow. 2:14 You might have what we call nocturia, which is nighttime urination, the need to wake up at night to urinate more than two times. 2:21 Men with severe cases of prostate enlargement end up with urinary retention. 2:25 That can lead to hospitalization or surgery. 2:28 Not fun. 2:29 Pharmaceuticals are conventional medicines treatment for enlarged prostate, but they can carry risks such as sexual dysfunction, 2:37 breast enlargment, fatigue, increased libido and headaches. 2:42 So one of the fundamental causes why men are prone to prostate enlargement are hormonal changes. 2:49 Your prostate gland is very hormonally sensitive. 2:52 I'm going to review the main hormones that affect the prostate and you can understand what is making you susceptible to Prostate enlargment. 3:01 Most of research is focused on testosterone, dihydrotestosterone, progesterone and estrogen. 3:07 Let's start with testosterone. 3:09 The first thought for many people is that high testosterone is the likely culprit behind prostate enlargement. 3:17 However, testosterone levels decrease as men age and their testosterone level drop, of course. 3:23 So we do not find prostate and enlargment to be a common for the males that are in their teens, early twenties when testosterone's at its highest levels. 3:33 That does not seem to correlate. 3:34 No, Testosterone really is not a driving factor when it comes to prostate largemen. 3:40 However, dihydrotestosterone is different. 3:43 This is a metabolite of testosterone, which is associated with prostate enlargement. 3:48 The prostate gland contains tissues that have the enzyme 5-alpha reductase, and this enzyme converts testosterone into dihydrotestostrone, 3:57 again, known as DHT. 3:59 Now, DHB binds to androgen receptors in the prostate and stimulates growth, so this is not a good thing. 4:07 Now, when we're younger, DHT stimulates prostate growth when they're in the womb during the fetal time period. 4:13 However, DHD continues to stimulate prostate grow later in life. 4:18 We know that men with prostate enlargement have much higher levels of blood DHP levels or concentrations compared to healthy men their age.
Hormonal Causes: Testosterone, DHT, and Estrogen 4:27 Furthermore, higher level of DHD increase the enzyme activity of the five alpha reductase, which again seems to be related to prostate largement. 4:36 There can be other reasons too. 4:37 There could be genetic reasons that affect the androgen receptors. 4:42 Ingenesis can known as polymorphisms. 4:44 And this research has also been shown to relate to prostate enlargement. 4:48 These receptors are found in high concentrations in the prostate gland influencing the binding of testosterone and DHT as well as the regulation of genes 4:58 that can affect prostate. 5:00 You've done everything you were told to do and something still feels off. 5:04 At Health Breakthroughs with Dr. 5:05 Stengler, we go beyond symptom management to explore integrative, science-backed approaches to the issues that medicine too often overlooks. 5:13 Chronic fatigue, brain fog, gut dysfunction, inflammation, hormone imbalance, and healthy aging. 5:18 If you're ready for real answers and practical tools to support your health naturally, follow Health breakthroughs of Dr Stegler on Doctor Talks or wherever 5:27 you listen to podcasts. 5:30 The other hormone which may surprise you, which makes men susceptible to prostate enlargement is estrogen. 5:36 This is a hormone again that influences prostate growth. 5:39 Although it's a normal part of the male hormonal system, most of it is produced in fat, brain, bone, and other tissues. 5:47 The production of estrogen is primarily controlled by an enzyme known as aromatase. 5:51 Now aromatase converts the hormone androstenedione, which is made by the testicles and adrenal glands, into the estrogen known is estradiol. 6:01 Aromatases also converts testosterone from fat and muscle cells into estrogen, known Increased activity aromatase seems to be a causative factor in men 6:12 with benign prostatic hyperplasia or prostate enlargement. 6:16 Men tend to accumulate fat as they age and this leads to increased aromatase activity, decreased testosterone, and elevated estrogen levels. 6:26 Age does not cause estrogen to decline the way it does with testosterone. 6:31 It's kind of the opposite. 6:32 As men get older, their estrogen level tends to go up higher. 6:35 There are other factors that you should know about that play a role in the formation of prostate enlargement. 6:41 One is a hormone known as insulin. 6:43 As insulin levels rise and people or men are predisposed to prediabetes and diabetes, that's a risk factor. 6:50 Insulin-like growth factors, like growth hormone may be a factor, even hormones like norepinephrine and angiotensin may a be risk. 6:59 We also know men who are obese. 7:01 who have a greater waist to hip ratio are more susceptible to. 7:06 And of course, there's always dietary concerns. 7:09 There's research showing that men that consume high amounts of animal protein, saturated fat and cholesterol, have high calorie intake, 7:16 they do not consume enough omega-3 fatty acids, or if you're deficient in vitamin D and zinc, these are predisposing factors to prostate enlargement as well. 7:28 When we see now hormones affect prostate growth, let's look at some of the natural supplements that prevent this excess hormonal stimulation and growth 7:37 of prostate gland. 7:39 Hey everybody, I want to take just a quick moment and invite you to my website drstengler.com. 7:44 Here we have the supplements that we've been using with our patients for many, many years. 7:48 High quality and high potency supplements, very pure. 7:51 So, if you're looking for high quality supplements where you can notice a difference, both in how you feel and on your lab tests, 7:57 go to our website at dr.stegler dot com. 8:01 The first supplement I want to talk about is known as beta-cytosterol and it's one of several plant sterols. 8:08 It's found in many plants with higher amounts in foods such as rice bran, wheat germ, soybeans, corn oil, peanuts, avocados, 8:16 pumpkin seeds, cashews, some fruits. 8:19 You also find it in prostate herbal supplements like salt pimento and pygium africanum. 8:26 Now, sterols are produced by plants that are structurally and functionally related to cholesterol. 8:32 Now beta-cytosterol is the most abundant plant sterol consumed by humans. 8:37 and it's unique because it inhibits that 5-alpha reductase enzyme and as well it has anti-inflammatory properties. 8:44 So research has demonstrated that beta-cytosterol supplementation improves benign prostatic hyperplasia symptoms such as urinary symptom scores and flow
Other Risk Factors and Diet 8:55 measures better than placebo. 8:57 In one study of 200 men with prostate enlargement, the men were given either 20 milligrams of beta cytostrol three times daily or placebo, 9:06 Those taking beta-cytosterol had significant improvements in urinary flow, while the placebo group did not have any changes. 9:13 Another study demonstrated that 177 men with prostate enlargement who supplemented with 130 mg of beta cytosteral daily had significantly improvements 9:24 compared to placebo in terms of urinal parameters and quality of life scores. 9:29 However, Beta-cytosterol was not shown to reduce the size of the prostate gland. 9:35 And a typical dose for beta-cytosterols, 60 to 130 milligrams daily, it has an excellent safety rating. 9:42 The other supplement I want to talk about, and I'm sure you've heard about but I wanna give you some specifics how it blocks the excess hormonal effects. 9:49 and that is saw palmetto berry extracts. 9:52 And of course, very popular for treating prostate enlargement here in North America and Europe. 9:57 And this plant has a long history of use by Native Americans for the treatment of prostate and urinary symptoms. 10:04 This practice was later adopted by American settlers and Europeans. 10:08 Around half or 50% of German urologists prefer to prescribe plant extracts such as saw palmetto, rather than pharmaceuticals for prostate largement. 10:18 Now, several studies have shown the effectiveness of saw Palmeto in improving prostate enlargement symptoms, mainly focusing on an extract, 10:27 which is about 85 to 95% fatty acids and sterols. 10:32 This is a standardized extract. 10:34 Now, saw palmetto has multiple mechanisms that are likely responsible for reducing prostate enlargement symptoms. 10:40 First, it has anti-estrogenic effects, and it inhibits the conversion of testosterone into DHT in the prostate tissue, as well as intracellular binding 10:51 to receptors in prostate. 10:53 Now as with other herbal therapies, Saw Palmeto works best for mild to moderate symptoms and the earlier stages of prostate largements. 11:02 About 90% of men will notice an improvement in mild to moderate urinary symptoms or prostate enlargement within the first four to six weeks of starting supplementation, 11:12 with a dose of about 320 milligrams per day of a liposteric extract.
Beta-Sitosterol and Saw Palmetto 11:20 Now, a 2018 paper conducted a supplemental systematic review of meta-analysis of randomized controlled trials and observational studies of man with prostate 11:31 And so this data included a total of 27 studies. 11:35 Researchers found that salt metal extract reduced nighttime urination, known as nocturia, and improved maximum urinary flow compared to placebo. 11:44 Furthermore, salt and metal abstract had a similar benefit to those using the drug Tamsulocin. 11:50 which is also a 5-alpha reductase inhibitor, and relieving lower urinary tract symptoms. 11:56 And there was no negative effect on sexual function or PS levels in those taking the Soprametal. 12:02 They found a slight decrease in the volume of prostate size. 12:06 The authors conclude that Sopa-metal extract appears to be an efficacious and well-tolerated therapeutic option for the long-term medical treatment of 12:16 lower-urinary-tract symptoms with benign prostatic hyperplasia. 12:19 There's been another big review done. 12:21 It involved 21 randomized trials lasting between 4 and 48 weeks, and they compared it to placebo. 12:28 And SalpaMetal improved urinary symptom scores, symptoms and flow measures. 12:33 Also, Salpametl produced similar improvements in urinal symptoms scores compared to the drug Finasteride and had less adverse events than the drugs Finastroid. 12:44 The other supplement I want to talk to you about is Pygium Africanum, also known as Prunus Africana. 12:50 In it, of course, as the name implies, has a history of use in Africa for urinary disorders. 12:56 The active components of Pygium africanum appear to be ferulic acid, esters, which lower cholesterol within the prostate and reduce metabolites that contribute 13:07 to prostate growth. 13:08 Furthermore, PyGium contains sterols that reduce inflammatory compounds that cause inflammation. 13:15 And here's the hormonal effect. 13:16 They also reduce testosterone accumulation within prostate. 13:21 One study found that Pygym afrikanum had anti-proliferative and apoptotic effects, which means improving natural cell death on certain types of tissue 13:33 without affecting the smooth muscles of the prostate gland. 13:36 Now, pygium is beneficial when you look at studies and it has improvements on both prostatic and bladder function. 13:45 Another review of 18 randomized controlled trials involving over 1500 men and ranging between 30 and 122 days was positive. 13:55 Compared to placebo, Pygiamafricanum provided a moderately large improvement in the combined outcome of urologic symptoms and flow measures. 14:04 Now those supplementing PyGm were more than twice as likely to report an improvement in overall symptoms. 14:10 Nighttime urination was reduced by about 19% and there were other urinary flow markers which were significantly improved. 14:19 Side effects were mild and comparable to placebo. 14:23 Now a different study on Pygm in the Journal of Urology involved 209 patients with prostate enlargement who were given either 50 milligrams twice a day 14:31 or 100 milligrams once a then there was an open phase where 174 patients received 100 milligrams daily and the results were similar in both phases with
Pygeum and Nettle Root 14:42 regard to the effectiveness and safety. 14:44 After 12 months of treatment there is even further improvement and a review authored by urologists of the evidence for the treatment of prostate enlargement 14:53 with pygium africanum concluded that it has a long history of use along with strong enough published data to make it a quote useful drug for the urologist, 15:03 although it's not technically a drug. 15:05 And the recommended dose is 100 to 200 milligrams daily of a standardized extract, usually one that contains about 14% triterpenes. 15:14 It has no significant side effects and a small amount of users it may cause digestive upset. 15:20 Now let's talk about nettle root. 15:22 Nettle root has research showing that it is very effective in treating prostate enlargement. 15:28 It has a traditional use in Europe for the treatment of urinary tract infections as well. 15:33 The mechanisms for netdle root appear to be multifactorial and research has not identified them all definitively, but it appears to have an inhibition 15:43 of sex hormone binding glybulin binding to the prostate receptors. 15:48 It also reduces conversion of testosterone into estrogens by reducing that enzyme aromatase activity. 15:55 And it also has anti-inflammatory effects on the prostate tissue. 15:59 Now one study, which was a double-blind placebo-controlled randomized study compared nettles with placebo in 620 patients. 16:07 At the end of the six-month trial, those receiving the placebo were switched to nettle, and both groups continued to supplement for up to 18 months. 16:16 More of those receiving nettles, about 81%, reported improvement in urinary symptoms than patients in the placebo group, 16:24 where only 16% of them had an improvement. 16:27 Also, those taking nettle had a reduction in post-void residual urine volume, which is the amount of urine left in a bladder after urination. 16:36 from an initial value of 73 to a final value 36, so quite significant, where those on placebo did not see any appreciable change. 16:46 There was also a modest decrease in prostate size as measured by ultrasound in the Nettles group, but none in placebo group. 16:54 And there were no side effects found in either group In one other double-blind clinical trial, 100 men with prostate enlargement between the ages of 40 17:02 and 80 were given nettles, 300 mg twice daily, or a placebo for two months. 17:08 Those taking nettle had significant improvements in urinary symptoms, and those on placebo had no change. 17:14 The authors noted that nettles was extremely effective and safe for the treatment of prostate Now the combination of Nettle Root and Soprametal is popular 17:25 in dietary supplement formulas. 17:27 In one double-blind clinical trial, the combinations of 160 mg of SopaMetall and 120 mg Nettleroot was evaluated in 257 elderly men who had moderate to 17:39 severe urinary symptoms due to prostate enlargement. 17:42 The men were treated with this combination or placebo for 24 weeks. 17:47 followed by a 24 week control period, then a 48 week follow-up period which all men received the herbal combination and assessments that week 96 revealed 17:56 that the international prostate symptoms score was reduced by 53% and other improvements were noted in the treatment group.
Nettle and Saw Palmetto Combination, Closing Remarks 18:06 Also the combination was very very well tolerated. 18:10 So this combination is often used in dietary supplement formulas because the Combination has been shown to be quite effective. 18:18 Now if you're a man with prostate enlargement and you are suffering from urinary symptoms, you know a large part of the problem is the hormone sensitization 18:29 of the prostate gland. 18:30 And by using the dietary supplements I just talked about, you can reduce the effects of these hormones on the prostate, which can improve your urinary 18:39 symptoms and in some cases actually reduce decide your prostate. 18:42 Well, hope you liked this video. 18:43 Look for other videos I have on prostate health, men's health. 18:47 Many videos on women's, health and children's Health as well. 18:51 Thank you for being with me. 18:52 If you like this Video, make sure that you hit the like button. 18:55 Thanks for listening to Health Breakthroughs with Dr. 18:58 Stengler. 18:58 If today's episode resonated with you, please follow the show, share with someone who needs it, and leave a review. 19:05 It helps more people find us. 19:07 For more resources and wellness support, visit DrStenglar.com.
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