Retatrutide: Managing the Risks

Retatrutide shows promise as a weight loss medication, but it does come with risks. I want you to be informed. In this video, we look at  what we can do about minimizing the risks which include muscle loss, increased heart rate, and effects on mood.

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References:

Giblin K, Kaplan LM, Somers VK, Le Roux CW, Hunter DJ, Wu Q, Lalonde A, Ahmad N, Bethel MA. Retatrutide for the treatment of obesity, obstructive sleep apnea and knee osteoarthritis: Rationale and design of the TRIUMPH registrational clinical trials. Diabetes Obes Metab. 2026 Jan;28(1):83-93. doi: 10.1111/dom.70209. Epub 2025 Oct 15. PMID: 41090431; PMCID: PMC12673447.

Norton LE, Wilson GJ, Layman DK, Moulton CJ, Garlick PJ. Leucine Content of Dietary Proteins Is A Determinant of Postprandial Skeletal Muscle Protein Synthesis in Adult Rats. Nutrition and Metabolism 2012. 

Ely IA, Phillips BE, Smith K. et al. A Focus on Leucine In The Nutritional Regulation of Human Skeletal Muscle Metabolism in Aging, Exercise and Unloading States. Clinical Nutrition 2023.