Revitalize Aging With Peptide Bioregulators

Phil Micans, PhD

Thank you, Jen. It’s an absolute pleasure to be on your channel, and with all the good folks who are watching at home or in the office maybe. Some people still go to work.

Jen Pfleghaar, DO, ABOIM

How did you even get into anti-aging, peptides, and bioregulators?

Phil Micans, PhD

That’s kind of two slightly different questions. The first one is, that how did I get into anti-aging was twofold, one of which is quite often said by people. The first one was that, as I was a teenager, I always thought that I was aging faster than my friends for various reasons. It kind of was a little seed in my brain, I suppose, about what aging is and why some of us age differently from others, even if we seem to have the same habits, the same exercise, food, or whatever. Why? What is the difference? That was a kind of intriguing thing. The other one was having to, one day or a few days, go and see my uncle in the hospital, who’d taken a fall and hurt himself. He was, at that time, in the late 70s, or maybe just touching 80. It was a real eye-opener because, of course, because of his age, they put him in the geriatric ward. I’m sure most of the guys out there know that that word only means one thing. The public has a different perception of it, but of course, being geriatric means being 65 or older. But of course, the public thinks of anybody being geriatric as being somehow incapacitated in some way. It was a bit of an eye-opener to me to be sitting next to his bed, playing cards or chess or chatting or whatever it was we were doing, and looking at many of the other people that were in this ward who were enjoying a second childhood. And of course, you’ve come out of those places thinking, I don’t want that in my future. And so, and I have a little proposal to make to anybody that can do it, is that before kids leave school, send them to two places, one to jail, to see what life in jail is like. Maybe they’ll come home and say, I don’t want to go to jail, which might change the course of their lives. The other one is to let them go and visit a geriatric ward because they might turn out to be the next brilliant anti-aging doctors of the future, fighting this thing that we’re all trying to avoid. Those were the two things. Now fast forward, and then I got into nutrition, and that was a family reason because my eldest brother was very interested in cutting-edge nutrition. and he, in the early 1980s, was going to America and meeting people like that. Durk Pearson and Sandy Shaw, and so Ken and Bill came home from Life Extension, and he got very interested in the whole longevity side of it. So a little bit later on, they said, you should learn more about drugs because there was a demand for certain types of medicines in the field. Finally, because I found myself reading a lot, listening to a lot, and traveling to different places, it was about 2009 when I went to a conference in Istanbul, and I heard Professor Vladimir Khavinson talk for the first time about peptide bioregulators. And as we’ll discover, this came out of Soviet research in the 1980s and 1990s. It was a light bulb moment, an epiphany where, after he’d finished his lecture, I was riveted to my seat. I remember there being a coffee break after his lecture, and I didn’t leave the whole thing; I was kind of glued to my seat. Honestly, I’ll tell you, at the time I thought, well, either that’s one of the most brilliant things I’ve ever heard or because we don’t always accept things the first time we hear them, of course. It was about a year later, and of course, I went back and started reading more and finding out more. About a year later, I had the privilege to meet him again, this time in Brussels, where I managed to have one tete-a-tete with him. Then it sort of started to sink in. I must admit, it was over about two years that I got it sunk in. Then I had the honor afterward of going to Saint Petersburg in Russia and meeting the people at the institute, and I started becoming involved in getting this information into English. Now I don’t speak Russian, so I pointed that out right away. But, with translators, I was able to get the gist of this, and so that’s where it just exploded from. Sorry, that’s a long answer, but that is the answer.

Jen Pfleghaar, DO, ABOIM

It’s so fascinating. That’s interesting how you were a child and thought that you were aging faster. That’s very intuitive. I like your ideas about having your kids go to jail and in the geriatric ward. That’s the problem: these kids like coming out of high school. They think they’re invincible. They’re drinking all these energy drinks, and they’re like, well, there will be medicine to fix it all. No, you will be one of those people in the geriatric ward who does not have a quality of life. This is what anti-aging and longevity are about. It’s about not quantity because we can do that in America and the UK but we’re talking about the actual quality. That’s what I tell my patients. I’m like, it’s hard-wearing a continuous glucose monitor and doing these peptides and doing these protocols, but you want to be playing with your grandchildren, taking them to the park, and being active. That’s what we’re trying to accomplish.

Phil Micans, PhD

Everyone’s got their own goal, their own whatever. I don’t see anti-aging as everyone looking like Angelina Jolie or Brad Pitt. That’s not my vision of it. My vision of it. I wouldn’t mind. They said that, but my view of it is that we want to achieve three things fundamentally: to be lucid, to be agile, and to be independent. If we’ve got those three things, we can lead normal lives, and that’s what we want at the end of the day. I hope we can I hope we can achieve this. One of the problems, of course, that we face in society is two things: one is that allopathic medicine teaches us that one problem, one fix. As we all know, most of that is masking the symptoms and not getting to the course. Second, when you are young, you’ve got your whole life ahead of you. I don’t know about you, Jenny, but up to about the age of 30, I did think I was immortal. Most of us go with whatever the marker is when we realize it isn’t. But most certainly, somebody who’s 20 years old is not thinking about what’s happening next year. Never mind in another decade.

Jen Pfleghaar, DO, ABOIM

I agree. They’re thinking about the next day, I agree that if someone has a diagnosis or symptoms that aren’t getting fixed, sometimes they will be more apt to dig into these kinds of things, like peptides, or if they have a goal or a training goal. But the average person is not going to think about that. But that’s what I want to change. I want people to start thinking ahead, and you mentioned the celebrities. That’s just Botox and filler. A lot of that and plastic surgery. I was joking with my husband. I’m like, You think those people look good? I’m like, I want to look at their telomere length. 

Phil Micans, PhD

That is a brilliant point. You’ve done that because there have been instances in my career, and I can also talk from the Saint Petersburg Institute, where you look at individuals. The big one I can quickly tell you about is that I can’t remember the year, 2010, or the London Olympics anyway. Someone can look it up. It may have been 2012. The winners of the women’s gymnastics were Russia, and they won the gold medals. these. There’s a great picture of all these young ladies standing there with their coaches. In the middle is Professor Vladimir Khavinson, and they’re all wearing their gold medals, etc. They published a report on this because of what they showed those young ladies: How fit have you got to be to win a gold medal in gymnastics? You’re on top of the game. Of course, you looked at them and said, That fits, but it hides what might be going on inside. To get back to your point, these 20-year-old girls had the telomere length of 40-year-olds. Although I’m pleased to say they were corrected, it was partly through these peptide bioregulators. They also do the same with their cosmonauts because they come back from long periods in space. Of course, despite their exercising in space now, they are still very weak. So they try very hard to induce protein synthesis to get them back up to speed, as it were. So we all know that a little stress is good for a whole basis, as it’s referred to, but excess anything is bad. I always say that the curve is either a you or it’s a you inverted curve, and you always want to be in the middle.  If you drink too much water or too little water, what happens? You always want to be optimal in the middle. So whether it’s cosmonauts or whether it’s people doing extensive, extreme exercise, you can cause damage. that may not be visible on the outside. The classic version of that, of course, is anybody who does intensive aerobics—I don’t know, like a marathon runner. As an example. We’ve seen this. We used to do arterial stiffness testing on a lot of people. So we saw it in long-distance runners, particularly guys who were a bit older, in their 30s or 40s or older, because they don’t. This is a different story. This leads me off into the realm of Dr. Rich Lipman, who’s a pretty radical expert and wrote a fantastic book called Stay 40. If anyone wants to find it on Amazon, it shows that older people who engage in extensive aerobic exercise are doing themselves no favors, and it’s also a fact that those kinds of athletes don’t live as long as the average person in society. And so we’ve got to think about that and either change our habits or give ourselves protection; in this case, we would be free radical scavengers, of course. to continue doing it. We do change as we age, and we need to be aware of that, of course, and adjust our lifestyles to suit.

Jen Pfleghaar, DO, ABOIM

Those are great points that I’m sitting here thinking about. I’m like, in my 20s, when I was in medical school, I went through the craze of running half marathons, and I’m like, I was under extreme stress from medical school, and I was doing this smart training. But that was in medical school. But no one’s going to tell me that stuff. That’s why we have to kind of leap outside of conventional medicine and sick care to just keep ourselves. We have to advocate for ourselves, and that’s why.

Phil Micans, PhD

Are you optimal health as a pyramid? If we think of a pyramid, the base of the pyramid is the stuff you have to do a lot regularly. You could call it common sense. You eat right, you exercise, and you de-stress. All those good things that we all need to do on a very regular basis. But as you go up the pyramid for optimal health, you may want to do other things. The next obvious layer, which I would call the additional layer, would be detox. Do you go and take a sauna? Do you think there are certain supplements or foods that you’d want to eat to achieve certain goals? Of course, avoiding certain things as well. Then further up the list, you might start taking some minerals and vitamins, and as we get up to the bit that we’re probably most interested in, where you perhaps need to be working with a health professional, you might start looking now at hormones, peptides, stem cells, or whatever other emerging technologies are going to come up. There are lots of things that will fit into those categories. But I maintain that if you’re doing something from every layer, you probably have the best chance of having an optimal health plan.

Jen Pfleghaar, DO, ABOIM

Yes, and that’s exciting because it’s an easy thing that we can do, and learning is part of that. What exactly are peptide bioregulators?

Phil Micans, PhD

You’re right about learning. It’s a life that’s a never-ending learning experience. If I ever meet anybody who tells me they already know everything, the first thing I’ll do is leave the room because it’s a stupid statement to make. Peptide buyer regulators are, by definition, short chains of amino acids. principally Soviet and Russian research. When I say Russian, this is a Russian-speaking country. This includes places like Kazakhstan and the Ukraine. I’m not going to go into politics. But that’s a fact. That was under the Soviet regime. All those countries were kind of merged. Short chains of amino acids 234 now, and interestingly, it was the very famous Ivan Pavlova, who everybody knows, who made the dog salivate when he rang the bells. He was the actual man who originally discovered short chains of amino acids. He was in then and I’m talking 20s and 30s now. He was at the Saint Petersburg Institute for Biogerontology, which is where all this other research has come from. That’s no accident. But if you fast forward to the 1980s, I’m sorry, I’m jumping slightly ahead here. But when Vladimir Khavinson got a call one day from the Kremlin and they said that there are some nasty battlefield weapons, like a laser that would make anyone seeing it go blind, also, we have submarines, and we have people sitting in nuclear silos who are aging fast. Now, that may not be too difficult to work out if you’re in a Russian submarine sitting on the floor bed for six months, not too far from a nuclear reactor. You probably wouldn’t be too chuffed about that. But they said, find something that will help these guys. That was the impetus. It wasn’t an accident that when they looked back and said, Well, Pavlov looked into the short chain of peptides, what can we know more about them? That was the impetus to do it. That’s standing on the shoulders of giants. That’s how we progressed. So the short chains 234 amino acids. What makes that interesting is that they’re nano in size, and they survive stomach degradation. The interesting thing about these peptides is that they’re found in different foods. They are part of the epigenetic messages from food to our genes. What the institute has uncovered is that 21 specific short-chain peptides have been identified so far, at least commercially. And they made gene switches, so individualized gene switches, and they were different peptides. If you look at meat, for example, some of these peptides are in the different glands. You can get a liver peptide, a kidney peptide, a thyroid peptide, and so on. Some people have suggested that since our societies have become so fussy about what we eat, we won’t have to go back that far. Maybe a hundred years, maybe less, where none of the animals would be wasted, would it? In my country, England, the Edwardians had recipes for cooking testicles or all sorts of things that today we wouldn’t entertain, or even, simplistically, I wouldn’t eat the black meat of chicken. Whoever stewed bones for soup? But we’ve missed out and what we can say now is that we’re not getting those peptides from those food groups that are instructing our bodies, our genes, to do whatever the tissue or gland it’s involved with. It’s something fundamental. If I may just mention, the Russian studies, have been on animals as well as humans. Some of the largest studies you will ever hear of in humans. We’re happy to talk about that. quite recently from the University of Tel Aviv. Not that it’s a few months old; they’ve been using it on plants, specifically strawberries. They’re finding that the strawberries that are given certain peptides produce something about 30% more fruit than those that aren’t. Khevinson used to refer to it as a biological reserve. He said every cell has around a 30% reserve. He also used to equate the maximum lifespan of 120 with the average of, say, 80, as also not activating this reserve. That was one of his theories. So what we can say about these peptide bioregulators is that they’re fundamental. They are used by plants, animals, and humans.

Jen Pfleghaar, DO, ABOIM

That’s awesome. I was chuckling when you were talking about how we don’t like to eat the whole animal anymore. I’m going to try to make my cat food out of the chicken back. I was going back and forth with our farmer. I’m like, what could I freeze dry for? Because I got a freezer dryer, and I’m like, What can I do for the cats? But you don’t see all these animals walking around with autoimmune diseases. Like these big lions and tigers. and then they start getting sick if they’re in the zoos, and they’re like doing all sorts of stuff to them. 

Phil Micans, PhD

Yes, we force them to eat the wrong kind of food. Before we came on the scene, do wolves hunt around for canned dog food? No, I don’t think so. I’ve got to tell you one quick story. I hope you don’t mind. I hope everyone will bear with me. If not, then go and get yourself a cup of coffee for a minute. 

A friend of mine from some years ago now breeds poodles at a very high level. He’s had his poodles at Crufts, a big dog show in London. He can charge, like, £20,000 for a dog that’s like $25,000. He gets a lot of money. So that’s what he and his wife do. One day, he called me up kind of out of the blue. His name is Michael. He said, “Phil, I’m a bit desperate. He said We’ve got two poodles that have come out of a litter of two prize-winning dogs, the dog and the bitch. They’re not doing well. It’s turned out that they’ve got gout. It’s too much uric acid in them.” He said, “We’ve been to the top vet in the country, which is in Cambridge, England,” And they’ve said, “Listen, these dogs need dialysis or they need a kidney transplant. We don’t do that in the UK. They were saying the only option you’ve got is to take them to America. It’s not going to happen.” He said to me, “What can we do?” I said, “I love dogs, but I’ve got no idea about their biochemistry.” But if you were a human being and you said, Listen, is there any simple thing I can do to lower my uric acid level? I don’t want to take a drug. I would say eat cranberries or dark cherries because there’s a specific acid in there, which I’ve forgotten the name of at this moment in time, which, as you may know, helps to excrete uric acid through feces. Anyway, long story short, they went out and bought big bags of dried cranberries, and they went into their kennels. I don’t know. They’ve got probably two dozen dogs or something. They came in with a regular chow, they came in with the cranberries, and they put them down on the ground. He said it was amazing. He said every dog, of course, had a look at the new food that came up and had a good old sniff. None of them touched it except for the two dogs that had the problem, and they devoured them. 

I’m very pleased to say that both dogs went on to lead a normal life. So much so that when they sent a video of their dogs to the vets, they didn’t believe them, and they had to bring them in to have their tags scanned. They didn’t believe these dogs could be living and that they should be dead. Michael said the only strange thing about the dogs was that their poo was black. But I said that that must be a sign of the uric acid that’s coming out. That’s all I can imagine. But the point I wanted to make in that rather lengthy story is that we have that ability for animals can sense what’s good for them and what’s maybe not good for them. We have it too. But for various reasons, we’ve lost most of that.

Jen Pfleghaar, DO, ABOIM

I agree with that. We shouldn’t always blame ourselves. We’re up against, like in America, all of these big food companies that are putting in all these addictive chemicals. You think that you’re craving something, but you need to check for that craving. Is this true? I love this; I’ll go on a little tangent. The story. After I had my son, Emery, I was just craving broccoli. I feel like, with his pregnancy, I was in tune with nutrition, and I ate excellently. He was a big baby to lose 10 pounds and ten ounces. Which is funny because I was far from diabetic. I was eating amazing food. That reduced my carbs a couple of weeks before I had him. I was craving all this broccoli and green juice. What does broccoli do? It helps detoxify those toxic estrogens. I was like, That’s so cool. I would feel like cooking an entire serving, like a family serving size of broccoli, and just eating it with butter, grass-fed butter, and salt. I was like, This is so cool. My body just knows what.

Phil Micans, PhD

Probably because you were pregnant. Probably an extra special reason. We’ve got somebody else to help here too. But there’s been research where electrodes are being put on the back of the brain. This brought the so-called horse brain back here. The people have been put in the rooms and read a book or whatever. There’s a one-way mirror, and they just monitor, and the electrical activity goes up when people are looking at them. But you don’t know if anyone’s looking at you because you can’t see anything. Our forebears are walking through the jungle and they know that a saber-tooth tiger is looking at them. They started running before they saw it because they got the signal.  Those things are that. But we’ve lost them. But to come back to peptides, they are something fundamental in food. We helped to write this book here which we called peptides in the epigenetic control of aging. That’s our science book on the background to all of this: how they work and why they work out. Because the amazing thing about this is that these peptides are going directly to DNA. They’re not going to receptors; they’re going directly to DNA. The Russians have some of the most incredible slides you’ll ever see. You have to put on 3D glasses to see them. Then you see the DNA, and then you see these. They’re like keys; they just come in and they interlock. then they either activate or silence the gene. That is the most unbelievable part of peptide. By that, I just mentioned that we also wrote this public book called The Peptide Bio Regulator Revolution, which people seem to enjoy because it’s a quick read. Why did the name regulator come up? I don’t even think it’s being quantified yet, but I always give thyroid as an example because it’s a nice, easy one. As many people are now hypothyroid, it’s quite well known. A few people, of course, are hyperthyroid. If you were to take the thyroid bioregulator peptide, mostly if you were hypothyroid, it would activate the genes, and you would start to produce more thyroid hormones. But the crazy thing about this is because you say, well, it’s T3, T4, maybe I even take desiccated glandular porcine extract, which of course is quite popular now as well. Of course, you can. But the thing about putting a hormone in you every day is that you must monitor yourself. Because you’re throwing a hormone in, and you must. I’m not saying you shouldn’t do it with a peptide either, but the fact is, it’s like an adaptogen. That’s a way I like to say it puts you within a certain band. In fact. Question of the day: Do plant adaptogens work because they’ve got short-chain peptides in them? I don’t know; I’ve not heard it, but I just put it out there for you if that piques anyone’s interest. But it’s a bioregulator because if you’re too low in thyroid, it will activate the genes. But if you’re hypothyroid, it silences you and brings you down into a bandage. What else does that mean? That’s too weird for how I want to get our heads around, but these are the facts from the studies.

Jen Pfleghaar, DO, ABOIM

I just had to explain to a patient that I’m helping with Grave Disease, and she is on a regular biochemical protocol for that. Also, other peptides to rebalance her, T1 and T2 immune systems.

Phil Micans, PhD

Now, of course, we could add, being a recovering pharmacist. I probably should add that, if anyone’s on any other medications, they should monitor even more closely because, in such cases, there will almost certainly be a need to reduce the dosage of the drug. Maybe it depends on the circumstances, come off it all together. Thankfully, with thyroid, I like the thyroid one because it’s nice. There’s a very easy way to do it, and that is, to take your morning temperature when you get out of bed, see what you got, and then you can see the increments point by point, one degree Celsius, up or down, and you can titrate your dosages according. That’s the old-fashioned way of doing it. Before there were, before the blood test, of course, but everyone can do that.

Jen Pfleghaar, DO, ABOIM

Yes. And that’s a great point you brought up about the desiccated thyroid. That’s it’s pig thyroid. It’s porcine. You do get a little bit of bioregulator activity in there. You can’t give it to Graves, but you can’t give it to Grave patients because you’re having that T4 in T3. Because I was telling her about it, she’s like, “Well, I’m having hypo symptoms,” I’m like, “You have at your labs, you’re hyper, and you still have graves going on.” She asks, “Well, why can’t I just take the desiccated?” I had to teach her because the bioregulators like you said, are adapting. They’re turning on those genes to heal the thyroid, not just to mask it, not just to push it to do more.

Phil Micans, PhD

But that’s right. We should point out at this stage that, for any effect to occur, you must have that gland or tissue. If somebody has had a thyroidectomy, the peptide is not for them. Then you kind of have to go down the medicine route. Because that’s just the way. There are three peptides. I’ll just mention, that the testes peptide is in the prostate peptide and doesn’t work with women. The ovary peptide doesn’t work in men. But they’re the only three.

Jen Pfleghaar, DO, ABOIM

What you could do is, if someone doesn’t have a thyroid gland because it had to be removed. After all, conventional medicine failed them or because of cancer or something like that, you could look at the pituitary bioregulator or the adrenal. You can look at it and make something around it. Supporting it.

Phil Micans, PhD

That’s very true. Some of the most popular bioregulators are the thyroid is popular, and the adrenal is very popular. Some of them in some respects, work faster than others in terms of having an effect, so, adrenal, thyroid, pancreas—they’re very good. The most fascinating blood vessels, by the way, are synergistic with all of them. I interviewed Khavinson a few years ago, and we talked about about 20 different problem states. He said he recommended three peptides for each one, every single one, to get a synergy effect, every single one, a blood vessel. But it’s not a big surprise. Because if you’re improving blood flow, delivering nutrition, and removing more toxins, it’s pretty much going to help. But the other, the other one there. In my book, the most fascinating one is the pineal peptide because the pineal is this kind of mysterious gland at the center of the brain that could be doing all sorts of interesting things. But as the great Dr. Walter Pierpaoli from Italy, a melatonin expert, once said to me, I’ve always remembered and loved his quote. He once said to me, “Phil, think of the pineal gland as the conductor of the endocrine orchestra. What happens if you have an orchestra but no conductor? Should you make noise? But when you have a conductor, you make music.” We all know about the release of melatonin in circadian rhythms and what have you. But I would go further. This is backed up by the work of Dr. Bill Lawrence in America, which we can get into, and I’m sure one day if you haven’t already, you’ll interview him. It is the pineal peptide that is principally responsible for extending telomeres. Bill’s 150 patients, he’s shown that they all improve DNA methylation, although other peptides may be involved in that. If you ask me, is there a standout peptide? I would have to say it’s the pineal.

Jen Pfleghaar, DO, ABOIM

I love that. Now, can you talk a little bit more about the 30% reserve? Because that is such a cool point that these bioregulators, they’re going in there and they’re affecting the DNA. They’re going right in there and doing that. They’re tapping into that potential, which is what is helping with the telomeres, like the organ regeneration, you hear sometimes with biotregulator use.

Phil Micans, PhD

There is something that occurs in aging: mechanisms, methylation, or whatever you want to look at, become sluggish. Let’s call it that. And there are new, and there’s another side story here, which is a mind-blower but is not directly related to peptides, the heat shock proteins. I suppose I should say it, shouldn’t I? I don’t want to leave people in the lurch. There’s an Italian surgeon. His name is Valerio Di Nicola and he’s published on this, and then this is the University of Rome. Some years ago, they came together, and they said one of the problems with joint and hip replacements is that some very elderly and some very frail people are not allowed to do them because the operations are too dangerous for them. They said, “How can we help these people?” That was the raison d’être. Over five years, they discovered a way. They extracted ten milliliters of blood from the patient, a very small amount. Overnight, and this is where all the work went, they heat and cool this blood. They torture the blood, if you will, and it releases its heat shock proteins. Now, I’ve seen the result of this. It looks like a bit of a red trigger. What they then do, let’s say, is take a knee. The surgeon makes a small, and I’m talking about three millimeters, very small cuts. He is cutting where the mesenchymal stem cells reside. That’s the knowledge that you need to have. They don’t pierce the capsule. They then go to the top. I always tell people you have worse cuts if you fall off your bicycle. That tiny arm, they are three miles. They then put back in your heat your concentrated heat shock proteins. Then they had one, or two stitches, and then the job was done. You come in in the morning, and you’re off for lunch somewhere nice. It’s not a big thing. Now some of his patients have come back a second time. A few of them come back a third time. But here’s the amazing thing they followed up on in the published clinical trial, which you can find at PubMed. There are 400 patients in that trial. But he’s done a total of 2000 since the last time I spoke to him. But this isn’t all young people. These are people aged between 40 and 80. Every single one of them negated the need for knee or hip replacement. That cartilage regrew. How did that happen? These heat shock proteins sent messages to the mesenchymal stem cells to say, “Hey, wake up, get on with the job. What the hell are you doing?” Similarly, the peptides do the same job. It’s simply a wake-up call to go and get. It’s marvelous because what we’re talking about here is truly regenerative medicine. We’re just giving the impetus to the body to go and do what it used to do very well 20 years ago. 

Jen Pfleghaar, DO, ABOIM

That’s fascinating. Drugs can’t do that. There is a cartilage. There is a bioregulator. 

Phil Micans, PhD

There is a clean version of it as well, which most people don’t know, which we call Joint Pro. But that’s a topical. That’s also another area that people are getting very excited about. Although we’re not quite there yet in dental products. There is already a mouthwash, which is very interesting. Of course, outside of Japan and also in Taiwan, we’re beginning to see actual tooth regrowth. That’s a game-changer, isn’t it? Because I’ve always maintained, why shouldn’t we get a third set of teeth when we hit 40? The fact is, it looks possible. It seems to be possible. Who knows where this is going to take us? Who knows? Is there anything we can stimulate? Can we regrow our hair? Can we get our eyesight back? Who knows where these are? But peptides right now—it’s the buzzword right now—but they’re going to carry us for the next ten, 20 years. We’re going to hear more and more and more about this subject.

Jen Pfleghaar, DO, ABOIM

You’ve got to get on the train now because you’ll be ahead of everyone.

Phil Micans, PhD

You thought practicing the cutting-edge of 21st-century medicine was good. 

Jen Pfleghaar, DO, ABOIM

The amazing thing is that they’re safe. We know that.

Phil Micans, PhD

Again, it could be because of their bioregulator. For example, now and again I get a bodybuilder to contact me and say, “Phil, how do I get my testosterone levels sky-high?” You can’t win with regulators? Because I don’t know what you’re doing, but you’re probably already doing some other things where you’re pushing your testosterone. Accordingly, the bioregulator is going to say too much testosterone. It could even silence some genes and try to bring his natural testosterone production down. These are not suitable for people who want to get to some kind of super logical level, but they are pretty few and far between; most of us would just enjoy having a healthy level, but I’ve certainly seen plenty of men who have done before and after, just to get this example, a free testosterone test. They all enjoyed improvements. Then people will ask how long these improvements take. I would say it generally takes between one and three months. Of course, it depends on you, your condition, and how much of the dose you take. But the other great news is that when you’re using natural bioregulators, there is a difference between them and the synthetics. I’ll be happy to get into that. The Russians call them, the natural sitogen max, and they call the synthetics sitogens. The trouble in this game, of course, is that it’s like learning a foreign language with all these new words. That’s probably the problem with medicine in general. They have quite long-lasting effects, which is why, in the majority of cases, the 80/20 rule says that you take two capsules a day for ten days each month. You don’t need to repeat it. This is not something that you have to do every day, which could be the case if you were taking a hormone, for example, thyroid. Now, sometimes, if there is a medical need, the Russians will give the patient two capsules a day for 30 days, and they call that the intensive course. Of course, in the clinics over there, they use injections as well. But they always send everybody home with the capsules. in Professor Svetlana Trofimova, who has an eye clinic in Saint Petersburg called the Tree of Life. Go look it up. It’s in English as well. What they do there is more than remarkable. They treat some eye disorders. just to give one example, and we did do a book about this, which isn’t in front of me, but we called it The Eyesight Saviours. Again, on Amazon, there are different things in that book that we talk about, but there’s a chapter on her work in peptides. One thing they can reverse is that we, and if anyone knows, send me an email or something, because we are not aware of any clinic in the world that can do this. That’s retinitis pigmentosa. This is a rare, thankfully mainly genetic, disease where people go blind. But she has numerous accounts for people. I’ll just give one example. There was one elderly lady. You’ve got this topologically computerized image of the back of the eye. Black is no vision at all. Red is bad, yellow is so-so, and green is fine. In one eye, this particular lady was 99.0% blind. They gave me ten days of injections. How did they inject?  They are subcutaneously injected into the skin around the eye. into the orbit of the eye, they just do these little pinpricks. They did that for ten days. Then they sent her home, and they said to take two capsules every day. She came back, like, a year later, because she wasn’t living in Saint Petersburg. She came back, and the follow-up, topological computerized scan. She was 30% blind in the eye. Now, that may not sound like a hero situation to some people listening, but to take somebody from being almost completely blind to being partially sighted changed her life completely. She could see the grandkids; she knew where the furniture was in the house. Now, if you catch it earlier, not because that’s extreme, but if you catch it earlier, the results are much better. and that’s not the only thing they do. They do. cataracts, macular degeneration, etc., etc. I’m just using that as an example because we don’t know of any other place in the world that could make that kind of thing happen.

Jen Pfleghaar, DO, ABOIM

No, not at all. That just shows the incredible healing power of our body with the right tools, and with these bioregulators, we can tap into that healing.

Phil Micans, PhD

I will say one thing. What we’re talking about here is a hand-in-glove situation. What on earth am I talking about? You still need the materials. The genes can give in to this. Peptides can give the genes instructions. Those genes are still looking for the materials to go and rebuild protein, or whatever the situation is. I always liken it to a building site. If the men are there. but the boss hasn’t turned up with the blueprints, but all the cement, windows, and everything else. He said the job isn’t going to get done properly, and vice versa. If the boss turns up with the blueprints and the men are there with the materials, not much is going to happen either. It’s still a case of making sure that the body is getting the right materials, and then you’re now getting those gene switch switches, and that’s when the magic happens.

Jen Pfleghaar, DO, ABOIM

That makes a lot of sense. That goes with making sure you’re sleeping well, eating well, and reducing stress. Let’s just touch on stress for a little bit. That is something that I was talking with Bill Lawrence about, and he said that one of his people in these studies had a horrible year of stress and their telomeres were lengthening, and then they just stayed the same that big year of stress. I was like, That’s because I’m a mother of four. I feel like I try not to think of things as stressful, but stress is big. 

Phil Micans, PhD

Are there a lot of us who don’t? I’m a country boy at heart. But those of us who live in the big cities don’t even know that we’re under stress. You go out on the streets and you dodge people, and then you head off in the air trying to park the car somewhere, and you don’t. The bad air and all that, and you don’t realize you think it’s normal, but it’s not normal. It’s not until you go on holiday and lie on the beach for a week that you realize I was stressed. There’s no doubt the number one way to shorten your telomeres is through stress exhaustion.

Jen Pfleghaar, DO, ABOIM

But I was wondering, I’m like, well, how do I bet you with a horrible stressful year? If people’s parents die, you hear of all these things: divorce, job changes. I wonder if those telomeres would have shortened, and stayed the same with the bioregulator.

Phil Micans, PhD

Very interesting. What we can say is that the girls on the Olympic teams and the cosmonauts in space—that’s what happens to them. Yes, they are improved when they get back much faster when they take the peptide bioregulators. That’s why all this remained a military secret for many years because it was a way of making their troops superior if that’s the right word to use. It goes on all the time. I don’t think they’re the only ones doing this. In my career, if ever I’ve heard the words, this was a so-and-so military secret, I’ve always wanted them to tell me more. To give you one example of that, the drug Modafinil, which has revolutionized the treatment of narcolepsy and cataplexy, was a French military secret. The American government, the British government, and I’m sure many other governments are all doing the same. but, of course, they’re always ahead of the curve. There would be stuff happening now that we don’t know about, but who knows, it might leak five years from now, whatever. It might leak out, as George Bush once said, trickle-down economics. Maybe we’ve got trickle-down medicine as well.

Jen Pfleghaar, DO, ABOIM

As you said, they’re on the cutting edge because they need to protect their health and optimize everything. 

Phil Micans, PhD

I’ll tell you a story that was told to me at the forum I met at an American event, which was held in Vegas in December. I was over there. I met two American doctors who are dealing with the US military, and they told me that this is not unique to the US military. It’s happening pretty much across the board. They said they had a big problem. I said, What’s the problem? He said the youngsters that are coming up through the ranks aren’t the same quality that they were ten and 20 years ago. They haven’t got the stamina; they got the strength and got this, they got that. And they see a weakening of the military. What they’re trying to do is encourage the older guys because one of the things about being in the military is that you end up retiring quite early, at 50, 55, or something like that. They’re trying to encourage the older guys and girls to stay on a bit longer to make up for this deficit. so they’re actively interested in finding ways to make the troops their older troops, as it were, both more physically and mentally fit. So, there we go.

Jen Pfleghaar, DO, ABOIM

I heard about that too. It’s kind of crazy. We’re not doing well. There’s a lot of stress. There are a lot of environmental toxins and a lot of things that are aging us prematurely. That’s why we need to use these tools to combat that, along with other aspects of health like sleep and nutrition. It’s so cool. I wish I could talk to you all day. I love your stories, tangents, and all your expertise. If you guys have never heard of Phil Micans, just Google his name, and so many amazing things come up. I love what you’re doing for bioregulators to.

Phil Micans, PhD

I think on your site, Jenny, you’re going to have some links to me. Folks can download magazines free of charge and stuff like that. I won’t bore you with websites because they will be on your page anyway. That’s great.

Jen Pfleghaar, DO, ABOIM

Then tell us a little bit about your event.

Phil Micans, PhD

Thank you. In England, on May 25th and 26th this year, that Saturday, Sunday. The weather shouldn’t be too bad either. We’re holding a very intimate and luxurious event called the Profound Health Summit. In the previous one, we had Russians come over. Now, I have to admit, on this particular occasion, they’re not coming over, but we have a lot of very interesting speakers. It’s not just peptides, I’ll say that now, but we aim to put on a conference or seminar, whatever, with two aims in mind. three aims in mind, I suppose. One, we ask all the speakers: There are no CMAs we have. Why? Why haven’t you gotten any CMAs? We don’t want to be restricted. I want the speakers to tell us exactly what they think. Tell us what you think. Tell us what you know. Don’t be restricted by anything. That’s one thing. Secondly, we give the speakers plenty of time for questions and all the rest of it—because people want to learn. They’ve come there to learn not to have an idea and go. Thirdly, and we got this many years ago, the other main reason people come to such a conference is to network. Yes, they want to listen to speakers, but they also want to meet their colleagues and network at unique times. Not running from one lecture hall to another lecture hall, as the case may be, we have one speaker on that. How do we achieve that? That was very easy. We’re all in the same building. We all have breakfast together. We all have lunch together. We all have dinner together. Everybody, the speaker is not on stage. then flying home; they’re there for the weekend. Sort of 150, 200 people. We’ll limit it to that. It will mean you have the opportunity to meet every person that weekend. So that’s it, and we also hold it in a five-star resort hotel, which gives a little bit of luxury and all that. Anyone bringing their spouses along and who doesn’t want to go anywhere can play golf, go swimming, go cycling, go to the gym, whatever. So if anyone wants to look it up, profound-health-summit.com and you’ll see it all for yourselves. Bill Lawrence will be there, by the way, we spoke about that and Bill was going to give his first lecture on how his patients had some organ regeneration going on. I haven’t even gotten those details myself yet, so I’m very much looking forward to that.

Jen Pfleghaar, DO, ABOIM

That will be such a treat. Is this going to be a yearly event?

Phil Micans, PhD

We’re questioning that at the moment. Now, it’s quite a lot of hard work. We don’t make money putting on these conferences. We lose it. and I put a lot of my staff time into it as well. Even including that in the cost, we’re thinking of doing it every 18 months. It would alternate between, like, May and then October, and then May and then October. The weather’s not too bad either. And also because I don’t, it’s a bit like doing a magazine if you say, we’re going to have a magazine every month; they’ll come a month, and you’ll say, what have we got to say? What’s new? Nothing, then you kind of regurgitating, plagiarizing, whatever. I’d like to think that every time you come to a profound health meeting summit, you’ll say, that was you. That was interesting,? We have fun, too. I’ve even booked a surgeon comedian to talk at lunchtime because laughter’s the best medicine, isn’t it? 

Jen Pfleghaar, DO, ABOIM

I love it. Exciting. Thank you for all that you give to yourself and your passion. We appreciate it.

Phil Micans, PhD

Thank. You. Know, it’s great. I watch Doctor Summits whenever I can, and it’s a great channel, and there are lots of interesting people, and that’s what it’s all about, isn’t it? It’s all about all of us sharing what we know. It’s great.

Jen Pfleghaar, DO, ABOIM

Thank you so much for being here, Phil. We appreciate you.

Phil Micans, PhD

Thank you, guys.