The Use of Peptides in Chronic Illness

Gordon Crozier, DO 

Thank you, thank you. It’s so good to be with you again, so we’ll have to get together sometime soon.

Nafysa Parpia, N.D.

Absolutely, yeah. So why don’t you introduce yourself to our audience?

Gordon Crozier, DO 

Well, my name is Dr. Gordon Crozier. I was clinical faculty at the University of Kentucky for some time, and I worked there. While working there I actually became ill myself. I went medical disability, but nobody could really figure out what was going on with me. Nobody could figure it out the neurologist, the infectious disease. So I had so many different appointments with so many different doctors and it was just frustrating after a while. And because of that, I began to seek out other entities to figure out what was really wrong with me. And I found out that a lot of my chronic illnesses is that I had had most of my life were actually due to simple mold in lyme. 

So mold in lyme and that’s what this is about mold and didn’t realize I was living in a brand home that was full of mold. But because of that, I began to seek out entities to help people get better from this, because I knew I wasn’t the only one that traditional medicine couldn’t figure out what was going on with them and why they were ill. So because of that, I sought out. And so now I’ve had my own private practice for over 10 years now here outside of Orlando, Florida. And we’ve just loved it. And I love helping people. And it’s hard. It’s hard sometimes, but, and it’s a hard disease to treat. But you have to understand it affect every single organ system. So that’s the cool thing is you have to be good at everything.

Nafysa Parpia, N.D.

Because we’re because we’re accessing the body from multiple points. Let’s start by talking about peptides. I’m really excited about this. The role of peptides in chronic illness, it’s certainly changed the way I practice medicine using peptides in chronic illness.

Gordon Crozier, DO 

Yes, me too. So there’s many peptides. So about 10 years ago, I started using some peptides in medicine and we’ve, everybody’s probably using one and it’s glutathione. So GSH, glutathione is a tripeptide that everybody knows about, but a lot of people don’t understand that that’s a peptide when they’re talking about the traditional realms. But there’s other ones. So I began using something called thymus alpha one, and I loved thymus alpha one because it really helped a lot of these people with these inflammatory conditions. Because when you’re talking about chronic disease and when you’re talking about mold and mold toxicity, it causes oxidative stress and we’re inflammation throughout our body. And cause of that, we have to have something that helps turn down that inflammatory markers in those inflammatory markers. 

So I started using Thymosin alpha 1 and Melanotan II. Those were kind of my two key ones that I use all the time, because Melanotan II, although it might make you dark, it’s really a great pathway through the melanocortin system in decreasing an inflammatory response, including ACTH, it helps modulate that. So the ACTH the MSH. All the things coming down from the hypothalamus it really helps to dampen and really helps to control some of that inflammation. And some of the neuro inflammation. That’s not one of the ones that we call a neuro peptide a lot of times, but it really does help to bring down neuro inflammation. So that’s why I got so turned on to peptides as time went on, we started introducing more and more peptides all along. And you probably know one of my favorites that now is LL37 because it works so tremendously with our Lyme patients.

And so I love it and what it does for our Lyme patients, but it just our line patients, I’m finding all these other people with other viral vectors, and it really helps them to mediate that insult from those different vectors, either bacterial, viral parasitic, it really helps all of them. And I love it because it goes in cont junction with other medications or other antivirals that are homeopathic or whatever you wanna use. It goes along with all of them. So it doesn’t matter what your modalities are. And we’ve spoken a lot. I use multiple modalities, so I’ll use some traditional type stuff. Then I’ll use some more of a nature apathic approach, sometimes a homeopathic approach. It depends on the individual patient, right. 

What you’re gonna do, but I love peptides because they go along with all of it, And so peptides are so critical to my practice. And it’s probably because when you understand peptides in the source we have over 9,000 different peptides working in our body. So why would peptides not be something natural for us to use in our body to augment different pathways and help people to actually gain the potential that they really need? And that’s why I really started using them now with neuroborreliosis, I’m using a whole bunch of different peptides now. And I love all those the peptides that we can use that are available to us today. So we keep having more and more and it keeps expanding. Sure some of them have been taken away and the FDA has kind of squelched some of them. So we can’t use them all anymore, but the ones that we can use are so useful in our practice. And I just, love it. And I know you use them most well.

Nafysa Parpia, N.D.

Yeah, it, they have changed the way I practice medicine today. So most of my patients come to me with tickborne disease and mold and all kinds of infections and high environmental toxicant load, mass activation syndrome and inflammation as well. And so in the past, before I started using peptides, I would detoxify the patient first. And then I would try to kill the infections, maybe using herbs, or maybe using IV antibiotics. And sure enough, many people can’t even handle herbs. Let alone, IV antibiotics, right? And so then when I started coming in with the peptides, my favorites are TB4 FRAG and BPC157 and KBV to start with.

Gordon Crozier, DO 

Oh, those are wonderful.

Nafysa Parpia, N.D.

Yeah, to calm down the inflammation first. But I found that once I started with those, then it became much faster and easier for me to kill of their infections and detoxify them. They were less negatively, reactive. Cytokine cascade that comes with the infection kill.

Gordon Crozier, DO 

Exactly, and that’s why it’s so wonderful to use the different peptides. And I use BPC157 and I use TB4 FRAG I use something that’s kind of newer now that’s we’re able to get it’s called APB 7.

Nafysa Parpia, N.D.

Me too, yes

Gordon Crozier, DO 

And so APB7 is one that’s really helps to calm down some of that cytokine storm as well. And it really helps with the healing of the cell too. And one thing that is not supposed to be known for, but I’ve seen a really great response in some of your, in some of my histamine patients. So it’s been working for some of those people with mass cell syndrome and it’s really been helping them in it to a great degree. And I love it. And I use KPV too. I love KPV for the anti-inflammatory effects that it has as well. So all these peptides, you just kind of weave in and out of them. And that’s what I that’s what I do. I kind of weave in and out of them and kind of have developed a little bit of my own protocol for them but it’s just, but it’s really patient driven in what that patient is needing and the patient’s response. So I never introduced the neuropeptides until after people have been able to detoxify ’cause even detoxifying people, sometimes we couldn’t do that without ringing down the inflammation first, they couldn’t even handle anything.

Nafysa Parpia, N.D.

Exactly super, the people who every time you try and move forward, you just can’t, it sets them back. And I found that the peptides allow us to move forward. What, couldn’t have much quicker.

Gordon Crozier, DO 

Yes, I love it because the peptides actually help to number one, bring down an inflammatory response, but they actually like BPC157. It’s one of my ones that I love.

Nafysa Parpia, N.D.

Me too.

Gordon Crozier, DO 

Because it actually it’s a genetic modifier. So it helps to modify epigenetic SNPs. So if you have some SNPs, like say your HLA DRBQ, and you know that one that one’s for detoxification, for mycotoxins, and it’s can’t say chronic lime on there and different things like that. So it actually helps to modify some of these genetics so that they will express correctly so that you actually are gonna enable the person to detoxify on their own being, because that’s what that HLA is. It’s on the cell surface of every single cell. It’s a very important genetic that we have to take into consideration. But even those people with apple A apple B apple E BPC157 helps to modulate that. And I see it in time and time again, the other one that actually is a genetic modifier is GHK. So GHK I use it, GHK-Cu because you really need the copper portion of that enzymatic function to really open up certain pathways for enzymatic functions, but also in the enzymatic functions in the DNA. 

So, because people don’t understand that enzymatic functions that are going on in the nucleus of the cell, but you have to get to them and you have to modulate that and how they’re going to express. That’s how we can help a lot of our patients today, because since we’ve been able to use these yeah, we were probably getting 60, 70% of our patients better, but it was a long haul and it was a struggle. So with the advent of these peptides, things have shortened, they don’t need as many IV treatments, ’cause I know you do a lot of IV treatments, just like I do in optimizing with amino acids and phosphide choline and all those other things. But these actually help those go to work quicker. And you get better results faster. So I that’s why I love peptides. Well, you know me.

Nafysa Parpia, N.D.

Me too, yeah. I would say that somebody who had took three, maybe five years to treat, it might take one year to treat when we’re using the peptides.

Gordon Crozier, DO 

Right, exactly. So, and I like that because those people then can get back to life sooner. I just, I have several people that are just finishing up their treatment modality. And they’ve been with me for about eight months they moved close by me and they’ve been here for eight months and but they progress so well, because of peptides that they’re now free to go back to school or work or whatever they were doing before. And some of the younger ones that are really were missing out on high school or college, it’s nice to see them to be able to have that goal of getting back into college, to getting back into high school. And I had three students all in the same year that actually caught up on their high school. And they were actually able to graduate with a class that they had started with, but they were two years behind, but they caught up. And I just love that because it wasn’t that wasn’t the case before.

Nafysa Parpia, N.D.

No exactly, they would have to be away from school or work for a couple years. Two people can come to the clinic now for six, eight months and we give them really robust treatment plans, aggressively treating. But also gentle ’cause each person is different. When I say aggressive treatment, I mean ongoing treatment. Not aggressively push someone off the cliff, but really watching them, watching them like a hawk and consistent treatment is.

Gordon Crozier, DO 

Yeah I don’t like to push people too hard with treatment modalities because I’m kind of a different, I don’t, I believe the herxheimer reaction is a warning for us that we’re pushing somebody too far too hard. And I know there’s some doctors out there that believe that, oh, you gotta push them. You gotta herx ’em, they gotta herxs. And I’m not that person. I think if you’re you’re having a herxheimer oh, we’ve gotta back off. We’ve gotta think about all the pathways that are working. And which ones are not. And let’s try to give you the peptides that are gonna optimize these specific pathways and it will work well for them.

Nafysa Parpia, N.D.

Right, I feel like it agree with that. A lot of patients will say, oh, you can put, push me until it hurts. You can push me until I’m exhausted. And they say no. And then they say, if I hurts, doesn’t that mean that we’re doing the right things. That mean we’re killing. And I say, well maybe it means we’re killing the infection, but it’s too high of a dose. It could be the right medicine at the wrong time. So we’ve gotta back up, calm down on the inflammation with peptides usually. And then reassess where we’re going.

Gordon Crozier, DO 

Yes, because I there’s some literature out there now that those reactions when we push ’em too hard are actually causing some mitochondrial damage. So if we’re causing mitochondrial damage, then what are we gonna do to that person? And so usually, mitochondria, I dress towards the end.

Nafysa Parpia, N.D.

Me too.

Gordon Crozier, DO 

And I usually use VIP as one of my peptides to address the mitochondria towards the end of treatment modalities, ’cause I just, I figured it out the hard way. We didn’t have anybody to help us. So, we kind of figured it out the hard way, but we found out that VIP wasn’t working early on. In fact actually it had adverse effects early on. Even though they needed it and you could see it by their labs, they needed VIP. But introducing that peptides towards the end of treatment modalities really helped with some of that mitochondrial restoration. And so that’s why I like to do it more towards the end.

Nafysa Parpia, N.D.

Right, and that speaks about the cell danger response where the mitochondria are creating external ATP outside of the cells as a warning signal of persons sick here. And so, it might not be the time to rub them up because they’re not gonna, they’re just not gonna use.

Gordon Crozier, DO 

Right, right, exactly.

Nafysa Parpia, N.D.

The ATP in the right places. So definitely I use it as an after therapy as well.

Gordon Crozier, DO 

Yes, yes, me too. And I see great results with it especially wow. Everybody but especially my younger patients that used to be able to compete athletic wise, but then they got sick and then they couldn’t compete anymore. But I have several competing in lacrosse again, just because we got them through the process, got them through it. Some, unfortunately some of them get tested, so I can’t use pep tides on them much why they’re competing. But I continue peptides even after they’re done with me just to modulate all their inflammatory responses and everything. So I like to keep up with what’s going on with the patient when they’re done. With the intense treatment modalities, intense. In other words, they’re getting IV treatments several times a week.

Nafysa Parpia, N.D.

Right, exactly. ‘Cause what I notice about my patients is that they’re generally sensitive people. And so once I’ve cleaned up the infections, I’ve detoxified them, of course, using peptides all along the way as well and they get them better and they can now go have a life. It sometimes it’s easy for them to get knocked knocked off again. It’s they’ve got that immune system patterning that the body knows how to go right back into neurological patterning that the body knows how to go back into very easy. Oh, I’m finding that the peptides are helping to re-pattern the immune system. Neurological system as well, which is why people left with them after is so important too.

Gordon Crozier, DO 

Yes, yes, yes. Yeah, we have to re-pattern things actually help people to come to a realization that they are kind of fragile in the beginning. But I see as they go on in time, because now that I have people that we’ve done peptides on for six plus years now kind of ongoing kind of weaving in and out of things. Noticed that they’re kind of setting up where they don’t need as much or they don’t need as often. And they’re kind of really they’re changing modality ways and really remolding everything. One cabinet I wish we could have in the United States because I have some patients from Europe and they’ve been able to actually get this peptide it’s called humanin. Humanin is a very cool peptide. And it it actually helps to heal a lot of aspects in the cell. So not only mitochondria but the ribosomes and the cytoplasm it’s actually works in the matrix as well. So it is a very cool peptide. I had one woman that was really sick. 

She was from France, extremely sick. And she really had gone through all the modalities. She’d been all over the world getting treatment, but she really, nobody ever used peptides on her. And then, I found out, oh, there’s a place, not too far from you. You can get some peptides. So got are in contact with this person. We could use peptides and I would do it through zoom because I, she couldn’t come here for a long, she did come for a little bit of period of time, but she couldn’t stay real long, like a lot of other people. So she went back home, but we modulated her with peptides. She’s now doing extremely well. And that’s what I like, because she didn’t think she was told she would never be able to have children. We started her on humanin, her fertility came back.

Nafysa Parpia, N.D.

I love it.

Gordon Crozier, DO 

It was she actually just had her second child now. So it was, it was kinda cool. But we don’t have that peptide here in the United States, but I’m praying that we can get it here soon so.

Nafysa Parpia, N.D.

So Gordon, speaking of where to get peptides from, I’d love for us to talk about that to our audience, because now the hearings talk about these peptides and of course they want them and they’re gonna go to the internet and find that they can buy the them from there. And right, so we let’s tell, can you tell them why that’s not a good idea.

Gordon Crozier, DO 

So we don’t want people to go online and get these peptides. Number one, you don’t know the source of them. So where were these peptides sourced? Number two, I’ve been involved with some company and we actually tested some of those peptides. And some of ’em didn’t even have the peptide in that they were supposed to have in. They had a different peptide that actually wasn’t gonna benefit the person at all. So you are actually gonna waste your money. Yes, they might be cheap online, but they’re also can be filled with toxins. It might not be the proper peptide that they say it is. It not, might not be the strength that it needs to be for the effect that you need. So that’s why I like to go with a true compounded pharmaceutical peptide. So, and physicians as physicians, we have to write the order for that. But there’s those pharmacies are available out there and people can get them. You just have to go through the proper realms and it might be a little bit more expensive, but I find it a lo whole lot more safe.

Nafysa Parpia, N.D.

Exactly.

Gordon Crozier, DO 

I can tell you. So I had one, I like to lift weights. So I go to the gym and I have a lot of gym friends in the gym and they said, oh, I just got this peptide. And they said, and I saw the name of where it was from. And I said, oh, I wouldn’t use that peptide. And he says, no, I’m gonna use it. I’m gonna use it I don’t care. Yours is twice as much as what this one is, this one’s only whatever I forgot what it was. But, and I said, I seriously, I probably wouldn’t use it. Well, you know what? He ended up coming back about two months later and he was really sick.

Nafysa Parpia, N.D.

Oh no.

Gordon Crozier, DO 

But you know what he had? He ended up with mercury poisoning because there was mercury in the peptide he was using. So he was injecting himself with mercury every day because it wasn’t a legitimate company.

Nafysa Parpia, N.D.

That’s terrible.

Gordon Crozier, DO 

Yeah, so you don’t know how they’re created, you don’t know the toxins in ’em. So that’s a real life story just for anybody to realize. I like real life stories. That actually point to why we probably shouldn’t go down this route in using non-authorized peptides. So, because you don’t know the sorts of them. You don’t know, they actually tracked one back and the peptides were made in somebody’s garage. So one of the companies, I mean, we’ve, I’ve been on the end of some of these people getting tracked so it’s been interesting.

Nafysa Parpia, N.D.

Thank you for sharing that. I also know that they’re often not processed, well, correct? Like there’s this final stage in the processing of the peptides in order to make them bio available. And the compounding pharmacies do that. But typically when they’re making someone’s garage, it’s not happening.

Gordon Crozier, DO 

No, it’s not gonna happen. So you, yeah they have to become bio available. If they’re not bio available, then they just are not gonna work your body. It’s just, you’re wasting your money. It’s just gonna, and actually can be introducing more toxins to you because then you have to detox those non bio available forms. Nobody think about that, right?

Nafysa Parpia, N.D.

Right, right, exactly. Thank you for sharing that story. So did you end up having to do chelation therapy for him?

Gordon Crozier, DO 

So I had to do chelation therapy for him. So this cost him quite a bit because number one, he was gonna compete. He couldn’t compete. Because he became so sick, he couldn’t lift weights. And so, he was ’cause he was gonna compete in a body building expedition and he probably would’ve won ’cause was really, he was really buff, but even sick, he looked buff.

Nafysa Parpia, N.D.

Oh, wow, yeah.

Gordon Crozier, DO 

But you know, but he was really toxic from the mercury. So once we detox him from the mercury, we were able to get him back on track and then he did use my peptides. So now he’s getting ready to compete soon so.

Nafysa Parpia, N.D.

I love it, yeah. He’s lucky, he was lucky that he had you there with him to catch that because now not too many doctors would say, you know what, let’s take a step back and see what’s causing this inflammation. So we know that environmental toxin cause inflammation. Tell me more about that. What you see in your practice.

Gordon Crozier, DO 

So I like to do a whole panel that tests for heavy metals. It, we test for mycotoxins we test for environmental toxins. So very few times do I find that people have mold alone.

Nafysa Parpia, N.D.

Me too.

Gordon Crozier, DO 

Don’t have mold, right? They have mold and that’s the major thing, but a lot of ’em have like cadmium or they have a different heavy metal.

Nafysa Parpia, N.D.

Exactly.

Gordon Crozier, DO 

That’s associated with that.

Nafysa Parpia, N.D.

Exactly, it’s never just one toxin never.

Gordon Crozier, DO 

Never just one.

Nafysa Parpia, N.D.

Never, never just one bug. It’s not just lime or not just mold.

Gordon Crozier, DO 

It’s multiple ones, right? So and I find that they have a lot of either glyphosates or phthalates or different plasticizers. We’re using plastics so much in our society anymore. So that can be a real, a real issue for a lot of these people and we have to detoxify them. So we have to kind of, okay, which one are we gonna detoxify first? Because you don’t use the same things. To toxify all of them, right?

Nafysa Parpia, N.D.

So, you’re gonna have to use some DSMA and you’re gonna have to use some EDTA. We’re gonna have to kind which one are we gonna use first? And so kind of playing that role. So I do Sears markers on everybody and I kind of look at this Sears marker. So, depending on what I think is more integral at that point to hit, that’s what I’m gonna detoxify first.

Gordon Crozier, DO 

I always love talking to you because it’s the same we practice so similarly it’s so it’s fun. I do yeah I do the same thing. Measure all those toxins and then decide looking at their inflammatory markers. Oh we’re also, we’re part of Dr. Bruce Patterson’s long COVID group.

Nafysa Parpia, N.D.

Oh great, yes.

Gordon Crozier, DO 

And he has a great inflammatory cytokine test on his website.

Nafysa Parpia, N.D.

Oh wow.

Gordon Crozier, DO 

We’re using that test now to look at people’s inflammatory cytokines. Not because they have long COVID necessarily, but because inflammatory cytokines are universal, whether you have long COVID or tickborne disease or high environmental toxic load. So I’m looking–

Nafysa Parpia, N.D.

And all of those and there are several different tests available and even glycoaging. So glycoaging, glycans, you have inflammatory glycans or non-inflammatory glycans. They can actually kind of measure those now to see what is going on with those glycans. That kind of hits a different realm too. So I like looking at all that stuff. It really helps to hone down the picture on what way I’m going to hit first.

Nafysa Parpia, N.D.

Right.

Gordon Crozier, DO 

Right. People often wanna start with killing the bugs first I tell ’em no, no, no, not there yet. We have to prepare you for that, yeah.

Nafysa Parpia, N.D.

Sometimes we don’t even detoxify first

Gordon Crozier, DO 

Exactly.

Nafysa Parpia, N.D.

I don’t always go for that first. I try to dampen the inflammatory response first and the body needs a little bit of preparation, if you just start detoxifying them, you’re breaking down more cells as you detoxify them. So they have to have some kind of semblance of being built and ready for that detoxification and for what’s gonna happen because when you’re detoxifying, you’re actually causing and creating some oxidative stress.

Gordon Crozier, DO 

Right, exactly.

Nafysa Parpia, N.D.

So we have to undo some of that oxidative stress at the same time as you’re detoxifying. So sometimes I get rid of some of the oxidative stress first, calm it down and then go after the other things.

Gordon Crozier, DO 

Right, me too. And oxidative stress is normal as a part of an initial inflammatory response. We want that at first, but we want that system to shut down and our patients are stuck in this loop of oxidation, oxidative stress. So gonna cut that loop and then come in detox. But I cut that loop with the peptides typically.

Nafysa Parpia, N.D.

Yes, that’s what we do. That’s who peptides work.

Gordon Crozier, DO 

So that’s what’s so good about the peptides is because you can cut that loop. So I use ’em in combination if you have that loop that you’re really needing to cut down. Sometimes I start with KPV and sometimes I don’t, it depends on if I think it where’s that inflammation. And I’ll tell you just tell you my little hint on why I might start with KPV first, if they have high monocytes, because lots of literature state that monocytes mean bowel inflammation. So if we have bowel inflammation, that’s pretty high. So if you have monocytes more than seven, you’re beginning to have bowel inflammation. 

If you’re more than 10, then you have a lot of bowel inflammation. So if they are at 12 or 13 on their monocytes, I’m probably gonna start with KPV, BPC and TB4 FRAG, before I do any of the other ones, but then we’ll kind of get to some of those other ones, but that’s kind of my key I look for is what’s that differential, if they have high base fills on their CBC count, high base fills is directly related to interloop and six. So if you have basic fills of one or more, you have high, IEL6 inflammatory cytokines are out of this world. And we’ve got to dampen that down, so. That’s kind of what I one of the measures I look at just one of them.

Nafysa Parpia, N.D.

Right, I love it. I love that, and another thing I love about the peptides is maybe people have gathered this now that they’re hearing to speak about ’em, they’re very specific messenger molecules. They don’t give a necessarily a broad spectrum of information like everything else, almost everything else that we give, but they’re very, very targeted.

Gordon Crozier, DO 

Yes and because they are targeted, that’s why I like to use them specifically like the KPV for that mal inflammation, because I find that KPV works so great at that inflammatory response in the gut, in the gastrointestinal tract. So that’s why I kind of will pick that one. If they have high monocytes, that’s my first go-to whoop, this is what we’re going to first. And then we’ll weave in the rest of ’em and bring down the other inflammatory markers eventually.

Nafysa Parpia, N.D.

I love it. Are there any specific peptides you like to use to help the detoxification process?

Gordon Crozier, DO 

So for detoxification, oh gosh, I go to a lot of ’em so what’s my favorite one’s gonna be? So Let me kind of let me think for a minute here. I’m just kind of stuck in the thought, I don’t know why I’m stuck on my thought process, but for detoxification, I like to use things that are to kind of help. So GHKCU I know helps with some things. It doesn’t help with all things, but it does help with some things. And it helps with some of my people that have specific environmental toxins. If you have high glyphosates, The glyphosates kind of block some of the copper enzymatic functions. And so GHKCU is gonna help with some of that detoxification from that, some of the other ones that I’ll use or thymulin I’ll use thymulin for helping with some of the detoxification especially if I’m thinking that they have specific toxins related to thyroid issues. Because some toxins are going to be specifically targeted at your thyroid. 

So I’ll use thymulin for that. If I’m thinking about more neurotoxins, I kind of do something a little bit weird for that. So neurotoxins I’ll use now RG3 is not really a peptide, but I’ll use that because it helps to calm down some of glial microglial inflammation. So I wanna calm down some microglial inflammation first, and then we’ll start into the fact of doing peptides. And some people use nonconventional ways of using peptides. They’re not really for that. And they really should not be used IV, but I’ve seen them use IV and.

Nafysa Parpia, N.D.

Which ones.

Gordon Crozier, DO 

So like BPC157, it works well for that. And even KPV works well, IV wise and I’ve seen that used as well. And KPV is kind of one of those cool ones that if it’s used IV, it will actually help to modulate a lot of the endothelial inflammation that is going on vascular wide, everywhere. And a as you bring down that inflammation, they begin to spilling out some of those toxins automatically, which is kind of cool. It’s kind of a double edge thing. And it does more than one exact thing. So for as far as neurological, so sealant is one that really elevates bone derived neurotropic factor, but it actually helps with some detoxification, especially, and it can be cerebral. It is Cerebra protective. 

As well as helping with some of those toxins that are latched onto some of the receptor sites. So it really helps with that sealant does there’s Cerebra, lysin that I absolutely love. And it helps it. I think it helps with detoxification neurologically. Because that’s kind of the crux of my thing is I do a lot neurologically so I do neuroquants. I evaluate neuroquants all the time. I do something called CNS vitals. And I like to do the CNS vitals kind of towards the beginning and then we do ’em midway. And then we do ’em towards the end to kinda see the progression and then they can actually see the progression on how fast they can think now. They’re thinking much more clearly they’re getting things correct better.

Nafysa Parpia, N.D.

Right, people often will forget how much better they are. Three, four months in. And you say you weren’t able to remember why you went into a room. And now you’re doing your accounting. 

Gordon Crozier, DO 

Your executive functioning is much better. And a lot of these toxins, like mycotoxins, they’re gonna affect different areas of the brain. Other toxins kind of have direct effects on certain specific areas of the brain. So and it depends so what specific areas? So some type, some toxins like the caudate nucleus kind of the, our executive functioning area. So we’ve got to be able to get at that. And that’s why I like cerebral lysin because cerebral lysin kind is one of those things that kind of causes some, I call it washing of the brain, okay? 

It kinda helps to grab up some of those neurotoxins and really pull ’em out. So I use that in conjunction with glutathione and with some other modalities as well, like BPC157 and dihexa, I don’t use right away. Dihexa I use later on after their brains kind of beginning to work and function. That’s when I introduced dihexa. So dihexa is a nice peptide to actually help unless they’re coming in and they’re an Alzheimer patient, then I’ll go to dihexa and I just will kind of continue ’em on that, but.

Nafysa Parpia, N.D.

Right, it’s so personalized bottom line, right?

Gordon Crozier, DO 

Right, it depends on the individual person. So, c-lank and c-max ’cause those, I kind of using a lot of Parkinson’s patients, but it’s amazing how many there’s some recent literature that just came out about most Parkinson’s patients have a lot of environmental toxins in them. A ton of environmental toxins. I know we saw it back in 2017. Some articles came out about it, but now there’s even more articles about it really substantiating that Parkinson’s patients are probably actually environmental toxins and it, the way it affects them. So using c-lank and c-max along with cerebral lysin. So I use those three in combination on my Parkinson’s patients. Because it really helps with that. Now sometimes I do have to do some IV chelation form because some of them have heavy metals, sometimes some other stuff that we’ve really gotta get rid of some of those things.

Nafysa Parpia, N.D.

Exactly, so it’s like getting rid of the toxins while we’re supporting the entire system with the peptides.

Gordon Crozier, DO 

Right, right, you kinda have to do it hand in hand if you don’t, you kinda.

Nafysa Parpia, N.D.

Yeah, I learned that in my own way. When I first started using the peptides, I thought maybe I should just use them at the end of treatment. Maybe they’re more just a regenerative piece kind of like killing them mitochondria. And then I learned and realized, Ooh, I can use them at the beginning. And that’s what I ought to do because it’s modulating the system setting up the system for everything else that’s about to come and I keep them on them on those peptides long term.

Gordon Crozier, DO 

Yeah I do too. I keep them, especially some of ’em I keep ’em on very long term. Now my some of my mycotoxin patients that have had some pancreatic issues towards the end of treatment, then I’ll begin to have put them on MOTS-c which can actually help with some of that stuff. And I’ve recently really found some great results in some of my patients that I could not get their glucose under control after treatment modalities, they’re all cleaned up. Everything’s working well, they’re beginning to think again and everything’s working, but they’re still ending up with a high fasting glucose. I started ’em on semiglutide and I put semiglutide with BPC157 it’s just a one once a week injection. And the semiglutide really helps these people to modulate their insulin and glucose ratios in the pancreas, ’cause it’s actually kind of helps regeneratively in the pancreatic islet cells. So it’s kind of cool and what it does in helping that and helping the pancreas kind of restore rebuild and all of that. So, but I have ’em on BPC157 every day and then the one they do the semiglutide.

Nafysa Parpia, N.D.

Yeah, fantastic.

Gordon Crozier, DO 

So there’s so many different ways you can use it. You just, what I tell people is start using one or two and just getting used to that one or two that you feel the most comfortable with. And then you’ll eventually start using more and more and more and more. I mean, now we use PT141, Melanotan II, we use kisspeptin. We use all of these different peptides for all different functions, because I don’t know if you see it, like I do. But a lot of my younger, especially men that have been insulted with borreliosis with Lyme disease, they have extremely low testosterone levels and they were hit in their puberty ages.

Nafysa Parpia, N.D.

Yes, old men, their testosterone levels.

Gordon Crozier, DO 

They’re, it’s horrible. And what I’m finding with them is that kisspeptin is a really cool peptide to use with them because it really will help them build up or testosterone. It doesn’t happen real rapidly. So you have to have them on the kisspeptin for a pretty long period of time, but you begin to see their testosterone levels rise and rise and rise where they’re kind of almost up to a normal range.

Nafysa Parpia, N.D.

That’s fine you have to lose clomid anymore than for that.

Gordon Crozier, DO 

Right, right. Because you see so many, so many young men today with low testosterone levels, it’s just rampant.

Nafysa Parpia, N.D.

It’s high estrogen.

Gordon Crozier, DO 

Yes, high estrogen. So you do have to block those estrogens too, a lot of times. But, but I found that that really works. And a lot of times, those young, some of those young guys in their 20s that were sick when they were in their adolescent years, they don’t have much of a sexual driver or desire. And usually just a small fraction of melanotan II to with kisspeptin actually helps build that for them. And they’re really much more satisfied in their sexual relations. So, we are sexual beings and so it kind of helps you feel better about yourself.

Nafysa Parpia, N.D.

Exactly and someone need PT141.

Gordon Crozier, DO 

Yes.

Nafysa Parpia, N.D.

For that reason too.

Gordon Crozier, DO 

Yeah.

Nafysa Parpia, N.D.

Yeah. Yeah, yeah, they’re so appreciative that we can change that part of their lives as well.

Gordon Crozier, DO 

Right, right, do you use any for female anorgasmia what do you, what’s your preference for anorgasmia in people with chronic disease after they kind of threw their chronic disease to kinda help with that?

Nafysa Parpia, N.D.

I found that the PT helps.

Gordon Crozier, DO 

Yes, yeah.

Nafysa Parpia, N.D.

How about yourself?

Gordon Crozier, DO 

I do I use PT141, and then I also will introduce oxytocin along with it. And those who combined really will help some of these women that have been left post toxin exposure, either mold or environmental toxins, ’cause there’s some bad environmental toxins that really can cause that, but they, this really helps to augment that so they can begin to enjoy that part of their life as well. And cause you have to have both men and women, optimized.

Nafysa Parpia, N.D.

Exactly.

Gordon Crozier, DO 

Everybody needs optimized. I don’t care what your sexual preference is. We all have to be optimized.

Nafysa Parpia, N.D.

Exactly, yeah what are three takeaway points that you advise your patients?

Gordon Crozier, DO 

So what do I advise my patients? Number one is let’s begin to decrease our toxin intake. So number one, organic foods Let’s change how the chemicals that you using in your home. That’s probably try to go and they can actually save some money. And I give them key hints on things that they can look at and go to create their own like laundry detergent, which is a fraction of the cost and other cleaning utensils around the house. So that they’re cleaning their home and their home is free and safe.

Nafysa Parpia, N.D.

Right so Important.

Gordon Crozier, DO 

And to have a clean, safe home. Also, I usually do recommend environmental testing of your home. Do you have environmental toxins in your home? Do you have mycotoxins in your home? Do you have other environmental toxins?

Nafysa Parpia, N.D.

It’s so important because until they remove that trigger, it’s gonna be hard to treat the rest of the system. They’re just gonna keep getting assaulted with that–

Gordon Crozier, DO 

Right, exactly. So I had one of my patients who had their home inspected, got it all cleaned up. I cleaned her up. Well, her whole family, it was a whole family. I we cleaned up, but anyway, got them all cleaned up. All of a sudden she’s calling me. She says, I don’t know what’s wrong I’m so sick. And da, da, da, da. So she came in ’cause she lives in South Florida and I’m here in central Florida. So she came up, we, we did a long card visit. Do you know what I found out at the very end of our consult.

Nafysa Parpia, N.D.

Tell me.

Gordon Crozier, DO 

They built a new home and moved into a new home.

Nafysa Parpia, N.D.

Right away.

Gordon Crozier, DO 

So you know what I did? I did environmental toxins Honda. The off-gassing that happens in new homes is really huge. So she got sick all over again. Not because of mold this time, but because of it, other environmental toxins. So, you have to understand. And that’s why I tell people what, if you’re gonna buy something new, let it off gas first before you bring it into your home, even mattresses, anything, let it off gas first. Don’t just go lay on it right away.

Nafysa Parpia, N.D.

Exactly yeah thank you so much. It’s always so much fun to talk to you always.

Gordon Crozier, DO 

It is to you too, because we kind of have similar practices. We kind of practiced very similar. I remember the first time we started talking and it was like, oh my gosh, you do that? Oh yeah, I do that. Oh yeah, I do. So it was like, oh yeah.

Nafysa Parpia, N.D.

It was so much fun always is.

Gordon Crozier, DO 

It is so I can’t believe we already been on here for an hour so it’s.

Nafysa Parpia, N.D.

I know, right almost, I know. Well, thank you for this interview.

Gordon Crozier, DO 

You are welcome. You are welcome, you take care.

Nafysa Parpia, N.D.

You too.