Day 6 Mini Presentation – Reversing Mast Cell Activation and Histamine Intolerance Summit

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Day 6 Mini Presentation
Reversing Mast Cell Activation and Histamine Intolerance Summit

Transcript
Beth O’Hara, FN

Here’s what we’re going to cover today in our mini presentation, estrogen progesterone and mast cell. I’m going to talk about the three types of estrogen dominance cortisone mast cells and the GI tract and mast cell activation syndrome. So I’ll set you up for the talks for today. Just a reminder. We saw this image on day one but a reminder here this great simplified model of a mast cell from the 2017 paper by David Spiral at all. And in this model what we’re seeing mast cells have these different receptors on the outside of them that can register different things happening both outside and inside of our body. And what we’re talking about today is particularly these receptors for different hormones. So you can see down here this one for estrogen and androgens different types of sex hormones. But there are receptors for DHEA For testosterone as a type of androgen. Both of those are for estrogen for progesterone for cortisol and generally a relative excess of estrogen and testosterone tend to be a little more mast cell activating. Whereas generally progesterone and D. H. A. And cortisol when they’re in the right balance tend to be more massive calming. 

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