Exosomes: The Future of Brain & Body Repair
4 months ago
- Exosomes Are the Body’s Repair Messengers – Exosomes are approximately 100 nanometers in size (similar to a coronavirus) and consist of phospholipid bilayers containing mRNA and microRNA. Rather than stem cells engrafting into tissue, they release exosomes that signal local cells to de-differentiate, proliferate, and repair. They stimulate angiogenesis, rebuild extracellular matrix, and shift the immune system toward an anti-inflammatory state.
- Intranasal Delivery for Brain Conditions – Dr. Park highlights intranasal (submucosal) injection as his preferred method for neurological applications, arguing it bypasses the blood-brain barrier more effectively than IV delivery. Clinical use cases include stroke rehabilitation, trigeminal neuralgia, tinnitus, brain fog, and pediatric autism spectrum disorder (ASD), where improvements may stem from reduced neuroinflammation.
- Quality Control & Regulatory Awareness Matter – Exosome therapy is not currently FDA-approved. Dr. Park emphasizes informed consent, managing expectations, and sourcing high-quality products. He prefers manufacturers using Tangential Flow Filtration (TFF) over older centrifugation methods to reduce contamination risks. While complications are rare, possible side effects include vasovagal episodes or HSV activation.
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