Boost Your Health With Magnesium

Decker Weiss, NMD, FASA, PLC

Good. Thanks for having me.

Laurie Marbas, MD, MBA

Well, thank you for having me. Today we’re going to jump into this murky water of supplements and, before people, disengaging supplements. I want to get into one, you have done the research and are speaking to people who get lost in the sea of supplements as we described before. But you said there was an interesting story behind maybe Jigsaw Health. Also, the particular thing we’re going to speak about today. But can you tell us a little bit about the history?

Decker Weiss, NMD, FASA, PLC

Yes, I was. I’ve used magnesium as part of a hypertension protocol in a way that is more realistic. Magnesium can affect blood pressure health. It takes time. It doesn’t work in a day. It’s not a drug. It’s not even an herbal like Rauwolfia, that will work faster. It takes time. But I do not doubt the clinical that, in the end, when we look at demographic data, low-tissue magnesium states are a big contributor to hypertension in the country. One topic of interest in current research is the battle between calcium and magnesium in our brains and muscles. We’re turning into rocks as we age, and we need to get more magnesium. But sometimes supplements don’t fix it. Sometimes it’s dark, leafy greens and things like that. All of that stuff battles in my mind. I was approached. I always used a supplement called a Magnesium Forte. Frankly, it was out of Germany. It was the Nieper family. They did a lot of research on absorption, and for me, it was the best absorbed because magnesium is difficult to absorb. Sometimes we like that the milk of Magnesia doesn’t absorb. It’s great for constipation, and magnesium citrate doesn’t absorb. It’s great for clearing out your colon before a colonoscopy. But that’s not the one we want for blood pressure. We want it to get into our cells, tissues, etc. This company approached me, and I’m looking at it. It’s a small company out of Scottsdale, and its main product is magnesium. They want to run a study and see if their magnesium is better than others. Frankly, I sat down with them. I go, look, if it doesn’t work, this is a big mistake and a larger fish in a small pond career-wise. If people ask me about how you did this Jigsaw magSRT study yet you’re not using it, what happened? I’m going to tell them the date. It didn’t work out. I said, Look, do you want to do this? They said. We believe in the product. We believe in years of testimonials; their dimag-malate independently did have some data out there floating around. But we want to know if our version is better. We think it is. We want to prove it. I said, okay. And I was like, wow, they’re putting the business on the line here. Then the other thing about it is that we all want more research into natural products. Real research, not eight people. We gave it to eight people, and they felt better. We’re talking about at least one blind, a placebo arm. 

We know natural medicine products because patients don’t have the drive or financial incentive to do these big trials. We’d love to find out if fish oil would help protect from stroke and aphids, but we don’t want to run a big study. I ran a study on one of the difficult things about magnesium: how do you know if it’s working? Because in our bodies, 1% of our magnesium floats around in our serum, the other magnesium is doing its job. It’s in our bones; it’s in our vascular system; it’s in our tissues working. How do we prove it’s there? And nobody agrees. I’m sitting with this company whose main product is magnesium, saying, I just want you to know that we’re going to have to extensively do a lot too in we probably don’t have a true claim out there like ibuprofen helps with a headache like that’s not going to be the endpoint here they’re like do your best years our budget and it was significant budget and I was like, okay so what we came down to is three things. Does it absorb? Okay, great. It doesn’t cause as much diarrhea; does it absorb, or does it assimilate? Does it get into cells? Even though it’s called RBC magnesium levels, a lot of people hang their hats on RBC levels, but yet science says that’s not the be-all and end-all. Science says the only definitive way of knowing how magnesium works is through clinical endpoints. We have well-established magnesium deficiency surveys that are accepted by the government, by names in all the studies, and things like that. The RDA says you need to get X amount of magnesium in your diet, but it doesn’t say how much has to be absorbed. When I generated the study, we did multicenter, two centers, single-blind. I would love to go double-blind, but that’s where it gets more expensive. But the single blind people don’t know who is getting the supplement; the people who are handing it to them don’t know what it is. Well, no, the people who had any tubes sometimes did something. The people receiving it didn’t go for placebo or not. We’re still blinded. We measured serum values. 

When they took the pill, we checked them at four and 8 to 12 hours. Blood draws. Does it get into the bloodstream? Those are the busy folks. We weren’t paying them to do that. There were a lot of patients, and there were a lot of volunteers, and they got as much free magnesium as possible. That’s it; that’s what they were promised. I know you bought nice people. Then the second thing was that in 30 days, at different points, we checked the RBC magnesium. That’s the simulation. RBC Magnesium, so serum values went up nicely. RBC values went up predictably, a little bit better than we thought. What we saw is that the more deficient, the faster the RBC came up. It makes sense clinically. That was nice. One of the other things we saw about RBC is that it seems like the body has a regulatory mechanism. When we do magnesium and IVs, if we do it too fast, you can stop a heart technically, in a cardioplegic solution. When we slow down our heart rates, When we work on the heart, we operate on hearts. There’s magnesium in that solution to give that heart a nap. But orally, we’ve always been worried. What if it was absorbed too well? We got these people dizzy and doing these things. What we saw was that it topped out and never went too high. It was like the body was still there. We liked that the body still had its regulatory mechanism in place to protect it. Then the third thing was the surveys, and that’s where the product shined. We consistently got some nice reduction in systolic blood pressure over about 90 to 120 days and even a little bump in diastolic, which is harder for natural products because it’s usually fluid volume and all that stuff. This product, whether it’s leg cramps, sleep, or magnesium, is like the thyroid; it’s involved in everything. When you improve it, you can expect a lot of effects. When we looked at those clinical endpoints, they were absorbed and assimilated, and we had clinical benefits, including some hypertension stuff. When we got those, I was texting them as I was watching the results because we didn’t, truly unblind until the end. I was texting the companies, and I said, I think you got a good magnesium. I said I might even use it to my benefit because I didn’t use it. 

When I went in, I was sticking with the one that had the best data that I did, and when it was unblinded in the data, it was crunched through. We had professional data, statistics, P values, all the stuff that we nerds know that shows, is the data real? You see, you looked away, and I said nerd, but you got to be if you’re interviewing me; you got to have some nerd in your hair. So we did all that. The data was great, and it exceeded anything. The Journal of the American College of Nutrition. This is what the JAMA, or Jack of Nutrition, agreed to publish. That’s why there’s a little company in Scottsdale. Getting into this journal was big stuff for them, and I was very happy for them. It’s also a lesson. This is a $3 billion company. I don’t even think, frankly, it’s a multimillion-dollar company. I don’t know how big it is, but they chose to do what they believed. It’s a great story because, in natural medicine, there are people who are taking, frankly, too many things based on hopes and possibilities. My patients—I don’t know if you’re seeing this, Dr. Marbas—my patients are coming in on too many supplements.

Laurie Marbas, MD, MBA

Yes.

Decker Weiss, NMD, FASA, PLC

There are way too many things. Should magnesium be taken every day? Maybe. It depends on the individual patients. From my folks, we’re trying to push down calcium and magnesium more in the body because they’re this yin and yang to each other. Sure. There’s a place for some people to take it every day. But it was fun to be part of this. When you see the success, that’s cool, and they’re very nice people. When we looked at it, they were like, What? We’re going to continue the investment to submit to these journals. That’s expensive, to be honest. You submit to these journals, and a lot of these journals say you submit to us; you can’t submit to anybody else for three months, six months, or a year. Again, they put it on the line here, so we’re going to, and there’s always journals where you can get anything published. In my toe, I got it published, so it was fun to be with, and the best if somebody says I want the research to prove it, I want something that meets the standards of the labels and all that. It is very reasonably priced. They do a bigger bottle, which I like because my patients keep throwing out 60-count bottles. It’s just filling landfills here, and if you’re looking at it, I think Jigsaw magSRT is a premium one on the market because they proved it perfect.

Laurie Marbas, MD, MBA

Perfect. Well, I love that you came in with the bias of, well if it doesn’t work, I’m not going to use it. This is very blunt. That’s nice that you can come away feeling confident, at least in this study, that there are biases in the actual and the principal investigator was transparent, that you were like, Hey, this is if it doesn’t work, this is nine work you’re going to publish. There were primary outcomes and secondary outcomes. What other things did you see that people were reporting back that they were benefiting, three and four months out?

Decker Weiss, NMD, FASA, PLC

Of sleep and leg cramps. You go into some of the personality things because we know magnesium cofactors into some of that stuff, a decrease in panic feeling stuff. We panic attacks even. Even some folks came down. Let me think. I’m just trying to think of all the things that were good endpoints, improved workout performance, recovery times, and things like that. But the main thing was that hypertension, panic, emotions, feeling generally calmer, and sleep were the biggest things that we saw.

Laurie Marbas, MD, MBA

We understand that there’s a mind-body connection. There isn’t a separation. When we think about the emotional piece of this, which alone can get the sympathetic nervous system on guard, and you see an elevation in hypertension from that standpoint, which do you think came first, the chicken or the egg? Can you describe the magnesium and the cellular level? What’s occurring with hypertension, or do you think it’s maybe multifactorial? What are your thoughts?

Decker Weiss, NMD, FASA, PLC

Again, magnesium does a lot of life-necessary work, so it’s doing a lot. My feeling is that it’s a great question. My feeling is that the physical vasodilators were first magnesium, vasodilators, and calcium vasoconstrictors. What about nerds like me? I’m not going to throw you that deep into the category.

Laurie Marbas, MD, MBA

I’m I’ve been known to be called a nerd too. 

Decker Weiss, NMD, FASA, PLC

We’re shifting the balance more evenly. We need calcium too. But we get from all our dairy products and everything we consume that we’re generally over-calcified, but people always want to promote some osteoporosis because there are a lot of reasons we get osteoporosis. But you’re putting that back, and I’m a cardiologist, so vasodilation is our thing. But I think secondly, a very close second would be smooth muscle relaxation. For everybody out there, leg muscles, all that, but in arteries, the middle layers of muscle. That’s one of the ways that vasodilator magnesium works—several ways to do that. But I think that the factor is that when people sleep through the night and I’m talking about good sleep, I always say more patient. It’s that sleep is like booze. There’s fine wine and malt liquor. When you’re pharmaceutically inducing sleep, you generally get the malt liquor of sleep, and your body doesn’t repair when you’re fixing sleep with either magnesium or it’s been nice. Jigsaw came out with the melatonin product magSRT. This whole race, when you’re naturally inducing sleep, now you’re getting the fine wine stuff, and then good things happen with good sleep. I think that those are the things that contribute to all the blood pressure. But I think in the absence, even if it doesn’t help you sleep better, you’re going to get some underlying blood pressure reduction, and we don’t have to. I was very pleased that it didn’t work too well. If it works, if it’s because these companies claim Dr. Marbas, 100% absorbed its nanoparticle size, if 100% of the magnesium absorbed, you’d pass out. It wouldn’t be there. We wanted to absorb it in natural ways, and we wanted to bring back homeostasis. We’re not looking to make you hypertensive. 

For example, when I prescribe pharmaceuticals to patients for hypertension, I always say I can’t overdo it. No, my pressure is too high. Yes, but when you get into cardiology, we’re going to ease it down. We can’t go too low. You pass out or you crash your car. I like the fact that whatever they’re doing with this dimag-malate, they’re their version of magnesium; whatever they’re doing, it is not over-absorbing and causing hypertension. That makes it extremely difficult when people say, What’s the safest magnesium? It’s going to be magSRT because I’ve clinically seen the RBC values not go overboard into levels where we might go. Hey, what’s the criticism from a lot of these Ph.D.s and medical doctors and the supplementation? Well, you don’t know. You haven’t proven it. It doesn’t do bad things. They’re to a degree related to historical use and things. We have edges on it. But we can say that in this trial it was very causal for prevention, that it won’t go too far either, that it’ll maintain a balance. It does it. When you look at supplements in the context of what we’re trying to do, especially with minerals, we don’t want to overdo it. When people take iron, they can get too much iron. That’s a bad thing, especially for the heart. Pressure is going up and inflammatory cascades. We don’t want hypermagnesia. This restores the balance that we want. That was, I think, particularly neat from a cardiovascular point of view. 

Laurie Marbas, MD, MBA

Interesting. What are the amounts, the milligrams that people are taking or that they took in the study, and did they see some improvement?

Decker Weiss, NMD, FASA, PLC

We generally did 1 to 2 twice a day as we ramped up. We wanted to see the difference in there, and I’ve got my little supplement facts box that I’m sure I didn’t memorize, or four tablets are 500 milligrams of dimagnesium malate. Then you have the breakout, the magnesium from there, and then their model uses some active, or what we call cofactor B vitamins, in there. That’s part of their SRT model that they, this was done on their SRT model. Nobody, no other magnesium, can make any claims based on this study. I have seen other companies with magnesium use the Scottsdale Magnesium Study as a reference for what magnesium can do. I have sent them a nice, polite email saying, Excuse me, your magnesium is not magSRT; please remove those from your site. I just did it. I was lecturing in Vermont, and they had this magnesium thing in there, according to the Scottsdale Magnesium Study. While that doesn’t have cofactor B in it, which I love to love in my heart patients, and all that stuff, by the way, these cofactors B are using Quatrefolic, which is a very expensive company. They’re not just using cofactor Bs; they’re using reliable ones to get it done. Those levels are what’s creating and helping to create this SRT effect that they have.

Laurie Marbas, MD, MBA

Can you speak a little bit about the different types? I know you mentioned the absorption issue, but magnesium glycinate, whatever the different types because people are, you’re talking about the magnesium, the slow release therapy, SRT, but what is the difference? Why is this one the particular one we should be choosing in this case?

Decker Weiss, NMD, FASA, PLC

Yes, in this case. And magnesium gets very complex because no other mineral has such a wide swath of effect. Low-cost magnesium can be of great benefit in medicine for constipation. It does not absorb; you don’t want it to absorb. When I think of those, the first one is the famous milk of Magnesia, magnesium hydroxide, which is cheap in every store and very gently helps with constipation. MagSRT is not your constipation magnesium. It is structured to be your complete opposite. Mag oxide, which is frequently taken for heart, and it’s not a good form of magnesium. Mag oxide, mag aspartate, I don’t put it in an absorbable category. Some people disagree, and there are a few opinions. I would say Mag citrate is not very absorbable, and you’ll see that quite often. If you want to know which ones don’t absorb well, frankly, go to a pharmacy. They will have the lower cost of magnesium citrate and oxides, and they will help you with constipation if that’s what you want. But they don’t label it for constipation. Label it just magnesium. Glycinate for me is the divider where it starts to get more absorbable. That’s why you see older companies that came out with magnesium; they’ll have mag-glycinate around. It was one of the first ones out there that absorbed better. 

When it came out, it was king. It was by far better. Then we got European influence through the orotates. It was Hans Nieper in the Nieper family who loved orotates. They broke in with lithium orotates, where you could take sub-pharmaceutical level lithium so you don’t get those side effects and all the drug interactions because it absorbed way better. They broke in with anti-psychotics. Crazy world. Then they had calcium orotates, and then their big one after lithium was magnesium orotates,  and you’ll still see lithium orotates, and these orotates out there. They had nice data. There you get the luxury that the governments quite often study it for you. They had that and that. I broke into practice in 2001 when I was done with training, and I used that until I started with the study. I did and worked okay, frankly. A lot of people still got loose stools and were unable to do it, and I had to go to creams and things like that to try and get mag again. When this came along, I was well, I’m waiting for the new king here. That’s what it is. On one end of the scale, the least absorbable will be your milk of magnesia. Then on the other end would be mag-SRT. Glycinate, it’s a little bit over the absorbable. It was a nice magnesium, and it helped people for a lot of years, but it’s simply out of date today.

Laurie Marbas, MD, MBA

Interesting. We have more questions, but just one moment. But I do want to say thank you so much for joining us today. I hope you found this conversation insightful and engaging. If you’re a purchaser, stay here, because we’re about to dive even deeper into this captivating discussion. If you’re not, click on the button below or to the side to access the rest of the conversation. If you’re watching this, thank you for being a valuable member of our community. Let’s continue with Dr. Weiss. I think an interesting question, because I’ll be starting to use this with patients and we’re going to be curious, is: What’s the difference between taking a supplement versus just eating more magnesium-rich foods? That will be the question; can this be done in that setting?

Decker Weiss, NMD, FASA, PLC

Boy, that sure comes up with calcium, too.

Laurie Marbas, MD, MBA

Yes.

Decker Weiss, NMD, FASA, PLC

Yes, it does. We need to be clear on this. When I look at calcium supplementation, Caltrate I don’t like it.

Laurie Marbas, MD, MBA

Yes.

Decker Weiss, NMD, FASA, PLC

Cardiologists have learned over the years not to like calcium supplementation because we’re seeing it end up in the arteries, and all that magnesium we have not seen, partially because it doesn’t absorb so well. You can’t control much of it, probably. With calcium, I’m a green leafy vegetable guy—dark leafy greens, green powders, PHs. I get into that deep. I’ll go into that, urine, saliva, and all that stuff. But trying to build. Some algae sources that are interesting, though. Magnesium, simply when we’re looking to fix a deficit, a tissue level deficit, it is my belief from the journals as well as what I’ve seen over 22 years of practice that you can’t fix that with diet. I just don’t see it. I’ve never seen anybody claim it. You’ll see a lot of people with calcium say dark leafy greens are the best way to get it in. Here’s the negative calcium supplement study. Here is the negative for this: and here’s the positive: dark leafy greens. I’m in Vietnam, where the strongest bones in the world, and the least amount of calcium consumption. But the morning I got the soup, and they took a bag of greens, cilantro, and some basils and threw them in the soup. Strongest bones in the world? Dark, leafy greens. I believe that you cannot replenish your diet, and it is reasonable to be skeptical about that. Look at the data.

Laurie Marbas, MD, MBA

Are there other things that you would prescribe magnesium for, especially in this particular SRT, like palpitations or some other things? We spoke about the leg cramping and a few other things. I’ve seen cardiologists recommend particular types of magnesium for palpitations, PVCs—those types of things that were uncomfortable physically but not necessarily harmful. Any thoughts on that?

Decker Weiss, NMD, FASA, PLC

Do I have my palpitation protocol on?

Laurie Marbas, MD, MBA

That would be fantastic.

Decker Weiss, NMD, FASA, PLC

Okay, MagSRT, 1 to 2, twice a day. I like to do that at bedtime. Even with the active B’s in there, if they’re homocysteine is eight or above, I see no problem with them taking it at bedtime. If everybody’s like, We don’t want to over methalate. Good thinking. No problem supporting you, but anything eight or over, you’re going to be fine. I will also use taurine between 2,000 and 4,000 milligrams twice a day, waking and bedtime. Then I like the herbals. There’s a combination herbal product called Cardiac Calm by Restorative, but there are a lot of combo oral formulas. They’ll tend to have things in there, like a glycoside source, usually Convallaria, or Strophanthus. It’ll have Passionflower and Leonardo’s Cardiacas. I do use an herbal combo. Cardiac Calm, which I think is the leader in the pack now, and I’ll do like two caps twice a day of that. With Convallaria having glycosides in it, this company needs to know its stuff. 

If it doesn’t have any glycosides in it, then you don’t have to worry about it hurting anybody, but it won’t help them. It’s got to have some. They’ve got to have that in there. That’s my protocol for palpitations. It is now that I will get a better immediate effect from the taurine in the Cardiac Calm; I will get a sustained effect, or to me, we can get a correction of the underlying problem over time with the magnesium on board. Because the taurine in the magnesium is fixing the deficiencies for me. The magnesium will take a little longer than the taurine to do that. But if we’re talking about a cure to the point where maybe they don’t even need the supplement anymore, you’ll have to have the magnesium on board. That would be my feeling on that. Did you have a question, Dr. Marbas?

Laurie Marbas, MD, MBA

Yes, can you describe and tell people just what taurines are doing?

Decker Weiss, NMD, FASA, PLC

Taurine does a lot of things. The main thing is that we do creepy things as doctors. We take organs and dehydrate them to see what they’re made of. If you’ve ever been to Path Labs, you’ll see this. This is a research lab. Yes. We took this heart and dissolved it. We found out that this was less than this. When we look at amino acids, they make peptides; peptides make proteins; proteins make organs. When we reverse that in the heart, it is quite abundant in taurine, and taurine is needed for two specific things in the heart. One is for even contraction and rhythm to function well. It’s like pulling a four-legged chair. You’re pulling one leg out. 

No, magnesium is like pulling the other two legs out, and then you don’t have anything needed for that. Taurine is also very involved in the GABA receptor. One last thing about taurine is that the digestive system, especially detox pathways, will steal taurine. You need taurine for phase two liver detoxification. It is my feeling only clinical; I don’t have any data on this, but it is my feeling that the body will pull the taurine from the heart and the system away from it for detox pathways. As we all know, detox pathways are prioritized quite often in the body. Our phase two livers are so inundated with everything these days that I think that’s why we become deficient in it. But magnesium gets you in and magSRT gets you in the game for true recovery.

Laurie Marbas, MD, MBA

Very cool. I think people have way more than just, Hey, take me on hypertension. They got an education in physiology, anatomy, and everything else.

Decker Weiss, NMD, FASA, PLC

Never give a cardiologist a microphone. It’s terrible. Yes.

Laurie Marbas, MD, MBA

Well, we appreciate you spending time with us for this summit. Again, tell us a little bit more about where we can find this particular supplement.

Decker Weiss, NMD, FASA, PLC

MagSRT. Go to the website, go to the full script, go to any of these doctor’s supplements, and what’s the one on the East Coast I keep forgetting? Well, the one on the East Coast.

Laurie Marbas, MD, MBA

Yes.

Decker Weiss, NMD, FASA, PLC

Wellevate.

Laurie Marbas, MD, MBA

Yes, Wellevate.

Decker Weiss, NMD, FASA, PLC

All of those standard things will do it. I think clinically, one of the last real practical things is with this study. I’m very appreciative they didn’t crank up the price. One of the things I advise them on is, look, if you’re in the pharmaceutical world, you’re Eliquis, you’re the one with the leadless. You’re going to triple your price. I said to myself, You’ve invested in this. It was a very interesting thing. They’re very active on social media, like Facebook. They have magnesium, social, everything, very good, and quite entertaining and funny. It’s a great group. But they said, No. We have our community. We’re good. We’re all going to raise prices if we have to deal with the economy. You get the bigger bottles—bigger bottles in the Magnesium world and for us, cardiologists are more compliant. When you’re just looking at simple compliance, the fact they have the bigger bottles is good. The last thing is, if you are concerned about methylation, some doctors are very concerned about over-methylated patients. They have a mag B-Free where they do take the active bees out. It was not the one at the trial, but it was magnesium malate. I have faith, and there are studies on dimagnesium malate, but I think it works the same. But they do have an element. They do have a version that does not have the active B in it, just called Mag B-Free. It’s a mag B-Free. But again, for me, anything homocysteine and up, I have no concern. At six, I don’t have much concern. I very rarely see over methylation, but just in case they’ll have the mag B-Free. But honestly, in the end, it’s the best absorber, and it’s got a big bottle, so your compliance will be better.

Laurie Marbas, MD, MBA

I’m just curious about it. We understand that homocysteine too high can put you at risk for certain things like stroke, especially if you’re B12 deficient and things like. Nobody’s ever I’ve never heard necessarily over methylation. What would be the consequence?

Decker Weiss, NMD, FASA, PLC

Of crop jitters, anxiety, or sleeplessness? I have only seen two cases. One was a teenage gentleman with autism who had a very odd methylation genetic issue. Before B’s, his homocysteine was two. Even inactive B’s would set off, hitting the real rough behavior. Then the last one was somebody who was referred to me, but they were doing IV Active B’s all the time, and they had some symptoms that could be explained by a few things. But I do know there’s a culture, especially in psychiatry and psychology, that gets more concerned about over-methylation. That’s reasonable. If you have that concern, they created the Mag B-Free. I think it’s because, in the cardiology world, we just need active B’s. I mean, it is a risk factor that I think my conventional colleagues have ignored for too long, and even when, I have surgeons and interventionalists who are good friends of mine. One of the things that I will say, they’ll go, give me one thing, I got two minutes off, like for homocysteine eight or under. Great. I will send you some bottles, mine is 16. 

Laurie Marbas, MD, MBA

Now that is interesting.

Decker Weiss, NMD, FASA, PLC

Let me add one quick thing. When you’re looking at methylation problems about getting homocysteine down, remember that magnesium is in the methylation pathway as well. So on those folks where they’re stuck to get homocysteine down. Looking at the lesser things, zinc for magnesium are around there, I think there’s some manganese thrown in there too. When we’re looking at whether we add TMG or stuff like that, we just go higher on a methylated B formula. Rather than looking at that, you may keep them on a good homocysteine formula, but look to add the magSRT because you might be filling in that deficit as well as helping them with methylation.

Laurie Marbas, MD, MBA

That is interesting. I’ve had a few patients who, when we measure homocysteine because I was eating a plant-based diet, worry about B12 deficiency. One of my supplements that’s non-negotiable if you’re on a plant-based diet is B12, and we measure homocysteine and methylmalonic acid, checking a few of those things. But for some of them, their B12 is fabulous. They’re not asymptomatic. Their methylmalonic acids or homocysteine are stuck in this elevated place. That’s interesting. Look at the iron and magnesium. Okay, that’s very helpful.

Decker Weiss, NMD, FASA, PLC

It’s my second thing, which is that they’ll have elevated homocysteine first. I’ll crank up the methylated B’s, all. And those that are stuck. It used to be TMG powder, and I never got a lot of success out of that. Even though those formulas contain TMG, I would try to overwhelm that pathway. I swap that for the magSRT, I get better portion reduction; no question about it.

Laurie Marbas, MD, MBA

Well, if I find one, I can now add it to your case studies.

Decker Weiss, NMD, FASA, PLC

In real effect. I love it for sure. Yes.

Laurie Marbas, MD, MBA

Yes. Well, anecdotal evidence is sometimes a glimpse into why it could be very helpful.

Decker Weiss, NMD, FASA, PLC

I’d better be worth something after 22 years. I better have something to give back to our professions here.

Laurie Marbas, MD, MBA

Appreciate that. Okay, great. Thank you, everyone, for watching. Check out Jigsaw Health and Magnesium SRT. If you have hypertension, it is very valuable. Thank you again.