The Effect Of Glyphosate On Digestion And Neurology

Stephanie Seneff, PhD

It’s so great to be here. Thank you. I just want to correct it, not professor, senior research scientist at MIT.

Sinclair Kennally, CNHP, CNC

Thank you. Of course, one very important distinction. I appreciate that. So let’s talk about this book that you have written. I mean, you wrote so many papers about glyphosate leading up to this. I mean, arguably the world’s foremost researcher on this scary topic and it’s affecting all of us. So talk to us about toxic legacy, how this came about, and then we’ll zoom in on the gut.

Stephanie Seneff, PhD

Yes. It has to start back in 2007 when I was looking at the autism rates going up every year. We’re just diagnosing it more. No problem. I didn’t think so. Something in the environment I’m going to figure out. I really wanted to figure out what it was and I know how to do statistical correlation between diseases and conditions. So I just started looking at things and kind of struck out. I looked for five years, I didn’t find anything obvious. I learned a lot about autism. I understood they had a gut problem, bloating, constipation, diarrhea. They had a lot of food issues. There’s food sensitivities. There’s just something wrong with their gut. That looked very clear to me. So I was thinking maybe something in the food, something poisonous in the food. That was at that point when I happened to be at a conference 2012, Professor Don Huber gave a two-hour presentation on glyphosate. I didn’t know what the word meant when I walked into the room, and now I can’t imagine not knowing that word because I think about it every day, all the time, Glyphosate. So and I was at the edge of my seat because everything he was saying about what glyphosate does, how it disrupts the gut microbiome, how it disrupts the deliveries, ability to detoxify other things, it messes up the metals, the mineral use of minerals makes them simultaneously toxic and deficient. 

It fit very well with what I was seeing as the symptoms of autism. Other they have a complicated set of co-morbidities and it fit very, very well. So I really felt I had hit a homerun with that presentation and went back and did some correlation studies, found perfect correlation between the rise in glyphosate usage on corn and soy crops over time and the rise in autism over time to coincide. If you look at the four years previous and integrate that the guidance that usage over the previous four years. Autism in first grade perfect match 0.99 Correlation coefficient. Unbelievable. That’s when I really felt this has to be right, and especially when I found out it’s all over the food supply and the government doesn’t bother to test. But many different activists have tested, have found high levels of glyphosate all over the place. So and especially in foods that kids really like, like Cheerios and goldfish crackers and Oreo cookies. So they’re getting heavy exposure to glyphosate in the food. Glyphosate messes up the gut microbiome. Then as we’ve learned your gut microbiome is very important for your health and you certainly know that. So that’s where it is, I think. I think it’s very clear to me that glyphosate not the only thing that causes autism, but I think it’s the primary cause of the epidemic.

Sinclair Kennally, CNHP, CNC

Thank you so much for unpacking that for us so let’s to go to that chapter in the book that you wrote about The Gate, which is magnificently written and just about how glyphosate specifically impacts the gut to create these chronic gut conditions that we’re seeing just explode today.

Stephanie Seneff, PhD

It’s hard to know where to begin, but certainly I could begin with the chicken meat pathway because that’s the pathway that has the enzyme PSP synthase, which is the enzyme that glyphosate famously disrupts. Everyone says that enzyme gets killed in the plants. The plant is essential for the plants. They die if they don’t have it. That’s how glyphosate basically kills all plants. The ones that have been engineered with GMO technology to resist glyphosate have been a version of that enzyme. That’s completely insensitive. The glyphosates comes from a microbe is inserted into the genomes using GMO technology of the plant so that the plant has this other version of the enzyme that can do the job that its own version can’t do when it’s exposed to glyphosates. It’s interesting to look at that other enzyme versus the one that’s broken with glyphosate because it’s a big difference between the two of them is a glycine residue. I want to get into this early on because this is, I think, a very important part of glyphosates mechanism of toxicity is that it substitutes for glycine by mistake during protein synthesis in certain proteins, and especially when it does it in critical places where those glycine are essential, it can kill the protein, it can completely disable that protein from doing its job and that’s what happens with the PSP synthase. There’s a highly conserved glycine residue at the place where the enzyme binds phosphate pyruvate. 

When you swap out that glycine for alanine, which is a minimal change extra methyl group, the enzyme is completely insensitive to glyphosate. So it’s a very specific issue that if you’ve got a glycine there, you’re in trouble. If you don’t, you’re not. That’s a huge clear to me that what glyphosate is doing is getting in there in place of the vaccine, especially because glyphosate is a glycine molecule except for an extra material stuck on this nitrogen atom. So it could fit into the slot of the enzyme that would allow it to displace glycine, especially if it’s binding to something that is phosphate because the methylphosphonate that’s on the nitrogen fits into the slot where the substrate is supposed to go. So the PEP is supposed to fit there and that makes room for the methylphosphonate of the glyphosate to fit in that enzyme and therefore it can easily substitute. 

That’s what I think is happening. So I was looking in my book at enzymes that binds to phosphate at sites where glycine is highly conserved, very specific. When you start looking at those enzymes, you see a whole set of enzymes that if they’re not working, it’s devastating and in many cases glyphosates has been shown to suppress those enzymes. So this is like fitting together the pieces of a puzzle, but it all makes very good sense if you say this idea that, like glyphsates substituting for glycine and because the code for glycine is what it says an enzyme makes a mistake and grabs glyphosate instead. There are enzymes, there are poisons that work by substituting for amino acids during protein synthesis. There are several different amino acids, not glycine. I don’t know of any other molecule besides glyphosate that can substitute for glycine, but other poisons have severe effects as a consequence of exactly that mechanism. So it’s not as if it’s never happened before. It’s just never happened before. With Glycine.

Sinclair Kennally, CNHP, CNC

So interesting. Okay. So for somebody who is new to this concept or has heard the word glyphosate, it’s likely that that’s banned. So I try to minimize my exposure with organic food when I can. How does this affect them when they’re in the middle of the healing process? Like how can they know? Like, is this a big deal for me or not basically?

Stephanie Seneff, PhD

I mean, how can they recognize the symptoms they might expect to have because of glyphosate? Yeah. Well, yeah. So it’s going to be a really messed up gut in many ways. So one direct consequence is going to be celiac disease. I think celiac disease. The reason for the rise in celiac disease and the sensitivity to gluten is glyphosate. I think it’s by far, number one, I would really be very confident in saying that glyphosate is a contaminant in which it’s sprayed right before harvest as a desiccant. So it’s not a GMO crops, so it’s not good enough to just buy non-GMO. But wheat contains glyphosate and glyphosate disrupts the enzymes. Well, first of all, it disrupts the microbes that help you digest the wheat, which is the lactobacillus. Lactobacillus are super important in the gut and they’re very sensitive to glyphosate, so they’re getting reduced in number. They produce enzymes that help the host to digest gluten, and that’s particularly because of proline. There’s a lot of proline and gluten and in casein. And proline is a difficult amino acid to break apart from the chain. 

It doesn’t work with the normal enzymes. It can do everybody else. So the specialized enzymes that break proline. That’s because proline has the nitrogen and proline is part of a ring that contains four carbons with the nitrogen embedded in the ring and so the nitrogen is not very easily accessible. So it is hard to break it apart. That’s why they’re these special enzymes and you can lactobacillus have several of these enzymes that proline amino peptides that break proline apart from the other guys. So when you can’t do that because the lactobacillus are being harmed by glyphosate, you end up with peptides within the from the gluten could get chopped up into peptides maybe five or six amino acids long containing proline get stuck because it can’t break off the proline. Then those peptides are basically four in sequences of amino acids that cause the immune cells to get upset. Some immune cells react to foreign proteins or foreign peptides by producing antibodies. Then there’s a process called molecular mimicry which can cause as antibodies to misfire and start buying into human proteins that have a similar peptide sequence. That’s how you can get thyroid issues because of allergic and allergies to antibodies to the thyroid to harm to molecule proteins in the thyroid that are involved with thyroid activities. So you get them thyroid conditions. That’s another thing that I think it’s causing and it’s connected to celiac disease. 

Sinclair Kennally, CNHP, CNC

I think a lot of lightbulbs are going off in the audience right now. So give them a chance to catch their breath because obviously we’re seeing an explosion of that. When I first saw your graphs about the glyphosate use having gone up year by year and how that was in lockstep with different various neurological conditions, fireworks are going off in my mind. I almost cried. I remember that very, very clearly. Now that we have this additional research from you, obviously, about the gut and its impact there, but this thyroid issue as well, it makes total sense. I would say the canary in the coal mine, we all know that. So are there any other diseases or conditions whose prevalence is going up?

Stephanie Seneff, PhD

Oh, my, that’s a huge question. That’s a thing. I had a lot of fun working with Nancy Swanson. She and I were rummaging through databases available online. They’re very convenient from the government hospital discharge data and mortality data and all these kinds of things, as well as, of course, the data on glyphosate and looking for diseases that are going up dramatically and then looking at the correlation and finding a huge list. I mean, it was amazing. She actually published a paper first without me. That’s how I met her because I published a paper in Anthony Samsel and shortly after that she published a paper with several coauthors that had over I think, 30 figures in the paper. Many of those figures showed perfect correlation between glyphosate going up and various diseases, and they included a huge list and this inflammatory bowel disease and even intestinal infection. So these things in the gut, celiac, she didn’t say do celiac, but we did see the celiac later, she and I and we showed good correlation with wheat that usage on wheat were better than with corn and soy. So it kind of fits because celiac is a wheat based problem. But we have autism, of course, ADHD, depression, sleep disorder. There’s Parkinson’s disease and diabetes and obesity are very strong. Both of those liver disease, kidney disease, liver cancer, even, I mean, thyroid cancer, which makes sense. Pancreatic cancer, pancreatic cancer, very strong. So, I mean, it’s just an incredible this Alzheimer’s there is very strong Alzheimer’s and dementia. So I mean, it’s amazing. People say, well, one chemical can cause so many diseases. Then they say correlation doesn’t mean causation. So we got to hit back, pushback on both of those accusations. The fact is, if it’s glyphosate, I think one chemical can cause all those diseases because glyphosates mechanism of toxicity is so central to metabolism that it just wrecks everything.

Sinclair Kennally, CNHP, CNC

So given all of that, where do you think people need to go in terms of taking their health back into their own hands? What would you recommend? Why don’t we want to take and take time today to get into your new research? So around this part right here. So if you have time to go into that.

Stephanie Seneff, PhD

Excellent. Yes. Well, of course, organic eating, certified organic diet, I think is the number one thing you can do for your health. It’s not perfect. Organic food does test positive for glyphosate, sometimes not because they’re using it, but because it’s pervasive. It’s in the rain. It’s often in the water supply, in the foods, of course. Of course, with the farmers, they can’t put a fence if the neighboring farmers brand glyphosate, they can’t keep those molecules out. So they do get some, but they’re much lower and sometimes test negative. So I think it’s very important to use certified organic and I’m really very thankful that our government has certified organic label. I think it’s more important than the non-GMO label for that reason because you can buy non-GMO that’s loaded with glyphosate and so. So thank God for certified organic. When we shop, we always if we can’t find it organic, we don’t buy it. We’re very strict and we’ve been doing that for over ten years now, ever since I became aware of how toxic chemical is. My husband, I just we did a big a throw away party, just took everything off the shelves and tossed it in the garbage because it wasn’t organic. It started growing several, many years ago. So and I think it’s made a difference in our health as well. We can see it.

Sinclair Kennally, CNHP, CNC

Yeah, I absolutely agree with you. I also had that throwaway party again. I was like, we’re doing this.

Stephanie Seneff, PhD

I don’t like to waste. So it’s kind of painful for me. 

Sinclair Kennally, CNHP, CNC

But it’s a real statement and when you look at the figures, it doesn’t take actually that many of us in the population to be eating all organic and to be asking for this and voting with our dollars this way in order to shift the equinox of large scale growing. So this matters what you do for your own body matters and manners for our community as well.

Stephanie Seneff, PhD

Yeah. Do it for the farmers as well as for yourself, basically, because the farmer’s going to be healthier if he’s not growing, exposing himself to all those poisons.

Sinclair Kennally, CNHP, CNC

Yeah. I mean, farmer kids growing up sick right now, it’s really hard to watch if we put them in our practice. Our group course is really sad. Devastating.

Stephanie Seneff, PhD

Of course. There’s that Non-Hodgkin’s lymphoma, which really did a number on Bayer. I’m very pleased with how that’s all come out and that was just amazing to me. When that first lawsuit, and when they won, I was just so thrilled. I couldn’t believe it because I figured that they always have lawyers that are so clever. They figure out how to get out of it. Then there’s been, two more big ones after that. Now there’s like tens of thousands or maybe hundreds of thousands, I mean, waiting in the wings. The Bayer who bought Monsanto is really scrambling to figure out what to do with this. In fact, they’ve decided they’re going to ban glyphosate use and they’re not going to sell glyphosate. They’re not banning it. They’ve just decided not to sell it, not to the residential market in America any time now I think.

Sinclair Kennally, CNHP, CNC

I think that starts at the beginning of 2025.

Stephanie Seneff, PhD

Oh, they pushed it back because it used to be earlier than that.

Sinclair Kennally, CNHP, CNC

But yeah, yeah. I think they need a little more time on this whole new chemical. That’ll be fun for you to actually.

Stephanie Seneff, PhD

It’s not going to be like it’s organic, it’s going to be some other toxic. Of course, all the herbicides are very toxic. I think we need to eliminate all the chemical based herbicides completely eliminate them and figure out how to do agriculture without them. After all, we live without them for so many thousands of years or millions of years, I suppose. So why do we need them? Yeah, it’s not worth it. The price we’re paying for those chemical based herbicides and of course, the insecticides and fungus sides are also bad.

Sinclair Kennally, CNHP, CNC

Thank you for saying that. I totally agree with you. We already know how to do this. So let’s get excited. Let’s do our own version of the Victory Garden again. Let’s unhook from the big food, big AG Because it’s not working too.

Stephanie Seneff, PhD

Absolutely yes, and of course, I really promote people eating not just certified organic, but Whole Foods stay away from the processed foods. I’m learning more and more about, I mean, all the stuff they put into the processed foods that are chemicals. You look at a soy protein bar, you look at the ingredient list and just wonder why anybody would want to eat that. Just looks like a whole bunch of chemicals. There’s no food in there.

Sinclair Kennally, CNHP, CNC

That’s so true. I was presenting on, like the seven most toxic foods to the liver and they’re all in protein bars.

Stephanie Seneff, PhD

Interesting. Yes.

Sinclair Kennally, CNHP, CNC

Protein bars are not healthy. Please step away from that. Let’s go back to Whole Foods.

Stephanie Seneff, PhD

Yeah. So buy your fruits and vegetables and cook at home and go back go back to what grandma used to do basically. I think a lot of young people don’t really know how to cook, but just like, okay, if I just take a TV dinner, put it in the oven type of in the microwave.

Sinclair Kennally, CNHP, CNC

Get excited about going on YouTube then, because there’s a lot of free cooking tutorials on there, guys.  So good. There’s no excuse.

Stephanie Seneff, PhD

You can learn how to cook from the web now. It’s much easier you used to ask the limit from mom, but now you don’t.

Sinclair Kennally, CNHP, CNC

Yeah, that’s true. Yeah. Speaking as somebody who had a mom who didn’t cook like this.

You type in and how do I cook? I learn how to cook hard-boiled eggs on the internet. Anyway, I want to dove into your new research today. I think in order to do so, we need to have a little bit of a frame here about and define a couple of terms that people may not be used to.

Stephanie Seneff, PhD

I think so, yes, the word is deuterium. That’s I’m very excited about deuterium. Lately, I’m really been digging into the research on that. Very interesting. I think central to metabolism, central to health and disruption of deuterium management in the body, I think is behind most modern chronic diseases. I think glyphosate disrupts deuterium in the body. So that’s the big message. Deuterium. What is deuterium? It’s heavy hydrogen. Hydrogen is the smallest atom. It’s on the upper left corner of the periodic table, one proton, one electron, verylean, mean and hydrogen is super, super important. All the metabolic reactions, it is hardly ever a reaction that takes place. It doesn’t include hydrogen somewhere. It’s by far the highest count. If you look at a number of the different atoms on the periodic table, which one will have the most count?. So it’s going to be easily hydrogen. We have a huge amount of hydrogen in our body. It hooks at all the carbons and everything else looks to be hydrogen and hydrogen moves around among molecules as part of the reaction process. So hydrogen is very, very essentially important. Central, I can’t really say enough about hydrogen as its roles in the body. 

So deuterium is a heavy hydrogen. It has an extra neutron, it’s like carbon 14, carbon 14 has extra neutrons compared to carbon 12. So deuterium is a proton electron and neutron and there’s tritium which has two extra neutrons that’s three times as heavy as the proton. So that the original hydrogen, they have hydrogen, deuterium and tritium and deuterium is not radioactive. So it’s safe in that respect, however, because it’s twice as heavy, it has very different biophysical and biochemical properties. So it doesn’t work the same as hydrogen and it’s scattered all over the place. So you have a lot of it actually. You have five times as much deuterium in your blood as you do calcium. So compared to the minerals, it’s high amounts, even though it’s small compared to hydrogen, it’s just because there’s so much hydrogen that even a small fraction actually is 156 parts per million of deuterium compared to hydrogen in seawater. So for every million hydrogen atoms, you have 156 deuterium, which sounds really small. But nonetheless, it really matters.

Sinclair Kennally, CNHP, CNC

Can you help explain because one of the adages in the deuterium space for people are nerding out about deuterium is that healthy deuterium levels in your body should be under 130 parts per million. Can you speak to that and how the relationship there with that and glyphosate?

Stephanie Seneff, PhD

Yeah. I mean the interesting thing where it started, I first learned about deuterium from a person named Laszlo Barros. Professor Laszlo Barros. Do you know him?

Sinclair Kennally, CNHP, CNC

I know of him, yeah.

Stephanie Seneff, PhD

Yeah. So he’s kind of a leader in that space.He was educated in Hungary at this event, Georgia Institute, which is when Georgia was this really famous guy who did all kinds of unique biochemistry. He was trained there. Hungary, Russia and Ukraine are the leaders in this research space, which is interesting, too. I think it’s an Eastern European Russia enterprise. It was Russians who first figured it out. The Russian scientists figured it out by looking at people who lived way up North in Siberia. They had a pretty bad diet in terms of fruits and vegetables because they had a very short growing season and they ate a lot of fish and meat and animal-based products, but they also drank water that came from the glacier. What they figured out was the glacier water had low deuterium compared to other waters substantially lower site under 90 parts per million instead of 156 much, much lower. They finally determined that they felt these people were living a very long and healthy life you know 110 to 120. They had really a good lifespan and healthy, really healthy throughout their life. 

So they suspected that it was because they were getting low deuterium in their water, that they were so healthy. That’s a very interesting place to start. So in general, I think if you just have less exposure to the deuterium, you’re going to do better. The foods have different amounts too. So you can eat animal-based fat, particularly butter and lard had the lowest deuterium of the different foods and chlorella make a fat. Also that’s low in deuterium so you can get deuterium in fats. Also probably avocado. Plant based fat can be low deuterium as well. It depends on how the fats are made. But fats are generally a low chain food, whereas sugars are hydrogen food. So you need a lot of carbohydrates and very few fats. You’re getting a hydrogen diet so you can influence your deuterium exposure from both your food and your water. The the rainwater at the equator has more deuterium than rainwater up North, because it’s an interesting reason, because when the raindrops fall, the water evaporates from the raindrop because it’s hot at the equator, more and more water evaporates. The water that leaves the liquid form that becomes gas has lower deuterium because the deuterium wants to stay in a liquid state, it tends to hang back in the liquid compared to the hydrogen, which is more readily shed. You see what I’m saying? Because hydrogen is lighter.

Sinclair Kennally, CNHP, CNC

So that’s very interesting.

Stephanie Seneff, PhD

That’s the same thing with the glacier water because the glacier water is water coming out of ice and the ice actually tends to hang on to the deuterium and the water that melts tends to have less deuterium than the water that stays behind in the ice. So that’s also interesting. So from ice to liquid. And then you have the gel, the gel water in the body which hangs onto deuterium and pushes out protons. Those protons that it pushes out or deuterium depleted. This is Jerry Pollock’s work, but he hasn’t looked into the deuterium aspect. But I believe what’s happening there is that the gel water is a mechanism by which people, mammals, all animals, actually trap deuterium in the gel so that the water that’s in the blood is going to have lower deuterium because the gel is trapping it preferentially, keeping the deuterium, releasing protons that are deuterium, lower deuterium. I think those protons that are released from the gel are fed into the cells along along the side of skeletal pathways, sort of like electrical wires and delivered to the mitochondria as low deuterium hydrogen and the very big idea is that the mitochondria hate deuterium, they hate it. Because it messes up the ATP pumps, just like sugar in the gas tank. The body works really hard to keep deuterium levels low in the mitochondria.

Sinclair Kennally, CNHP, CNC

I’ve never heard it said that way. It’s a really nice, memorable way to say it. Mitochondria hates deuterium because it slows down ATP production.

Stephanie Seneff, PhD

It causes reactive oxygen as well. So both it wrecks the ATP pumps, prevents ATP production and releases reactive oxygen, which can cause DNA damage leading to cancer.

Sinclair Kennally, CNHP, CNC

Okay. So then how does this affect somebody who’s chronically ill with that condition? Say so. Obviously you’ve got mitochondria. 

Stephanie Seneff, PhD

Yes.

Sinclair Kennally, CNHP, CNC

Your body’s trying to manage your deuterium.

Stephanie Seneff, PhD

That’s right. The gut microbes are really good at feeding the gut load and sharing food. This is really, really central. I think this is where the gut comes in and where glyphosate messes things up. So when you start to look at the gut microbes and what they do for the host, what they make, one thing you see is short chain fatty acids and in particular acetate and butyrate. You’ve probably talked about those two, right, acetate and butyrate from the gut microbes. And it’s very, very interesting because the acetate there’s gut microbes that make acetate and they make the acetate from methane gas and hydrogen gas. Very interesting. Methane gas is made from hydrogen gas and carbon dioxide. I guess the acetate may go directly. I’m not sure if they go directly from carbon dioxide and hydrogen gas. I think they do. Carbon dioxide and hydrogen gas, these bacteria are very clever and they can turn that into acetate. What that means is that they’re that the critical thing is the hydrogen gas, because the hydrogen gas is made by other microbes. It’s in it. How you have a lot of gas in your gut and you get bloating in all of this. Why do the gut microbes have to make gas? One should ask that question. Very much a part of what you did.

Sinclair Kennally, CNHP, CNC

A lot of people here are wondering that. Yeah.

Stephanie Seneff, PhD

Yeah. Well, there’s a very good reason and I love it and it’s actually very hard to find the research that supports this. But I was able to find I’m still looking for papers, but I found one from the 1960s, where they looked at hydrogen gas produced by microbes from formate and from glucose sugar. In both cases, the hydrogen gas had extremely low deuterium compared to seawater. Seawater is 156. The hydrogen gas had 30. 30 parts per million, which is fantastic. I was really surprised because that is extremely low. The reason, of course, is because this are not heavy it stays behind a liquid state. So basically these microbes can make hydrogen gas by pulling hydrogen off of organic molecules like glucose and formate. They make hydrogen gas, H2 and that hydrogen gas is then grabbed back into the system to make organic molecules again. So this process of making gas and then bringing it back into organic molecules is a process of shedding deuterium. I think this is extremely important.

Sinclair Kennally, CNHP, CNC

This is so interesting because a lot of our audience is going to be familiar with the concept of hydrogen producing bacteria in the gut and having vilified this because they’re experiencing SIBO. They can’t kick it and they’re taking antibiotics for it, they’re getting worse.

Stephanie Seneff, PhD

Oh, gosh.

Sinclair Kennally, CNHP, CNC

Yeah. So can you speak to that a little bit?

Stephanie Seneff, PhD

Yes, I can. Because so this is enzymes. So for example, they’re enzymes that there’s a fascinating path. So I’ve been looking at all these gut microbiome pathways with the angle of hydrogen gas because hydrogen gas is God. Now, because that’s got this very low deuterium and then the microbes want to turn it into something organic that can be metabolized to make energy, particularly can be metabolized by the mitochondria to make energy and they don’t want it to have a lot of jam. 

So that’s perfect. The butyrate that they make, they make the butyrate from the acetate. The acetate comes from the hydrogen gas. You’ve got beautiful butyrate with low deuterium that feeds the colon aside. So that lining the colon keeps the colon healthy. They love the deuterium.. That’s their favorite food. It’s made by the microbes and it’s made from the hydrogen gas. So it’s got low deuterium and so and butter, of course, is one of the lowest deuterium foods on the planet and it’s got a lot of butyrate. So it makes sense.

Sinclair Kennally, CNHP, CNC

So interesting.

Stephanie Seneff, PhD

It’s really. Interesting.

Sinclair Kennally, CNHP, CNC

Okay. So yeah.

Stephanie Seneff, PhD

Now you go ahead, and I’ll answer the question and we’ll fill in.

Sinclair Kennally, CNHP, CNC

So talk to us about glyphosates’ role in disrupting our own deuterium management. What does that mean for us?

Stephanie Seneff, PhD

There you go. Yes. That’s going to be the bloating as well. So, of course, the cows, they release a lot of methane gas that caused global climate change. We don’t want to have cows. Right. There’s like all this argument about. Good. For the planet because of the methane. Well, if the cows were eating organic, they wouldn’t have nearly as much methane. Because what’s happening is those enzymes, it’s a microbes used to convert the methane back into organic matter that can be metabolized in the body are broken by glyphosates. They’re broken. What happens is you make the hydrogen gas, you make the methane, but then you can’t get it back in because those enzymes are broken. You get a lot of gas, you’re bloated, you’re comfortable, and you’re not converting those to useful material that you can metabolize. So really interesting. So there’s a whole cycle that goes on in the gut, which is so fun because it starts with the hydrogen gas from formate. So you start with formate and the certain microbes make the hydrogen gas. The hydrogen gas is put together with the carbon dioxide to make methane and the methane is converted to methanol, formaldehyde, formate and back to CO2 the whole cycle. Right, all the way around. 

You can do that over and over again. It seems kind of futile. I just do all that. But what you’re doing is you’re pulling out that hydrogen gas and sticking it on to NAD and you’re making NADH. So those enzymes that go, all of them are making NADH. The ones that go from methanol to formaldehyde to formate to carbon dioxide, you get the NADH produced from that and all of them have got that H from H2, which is a very low in deuterium. So this makes the H on NADH to be extremely valuable because it’s going to be very low in deuterium, unlikely to be deuterium. Then the enzymes, these dehydrogenase as they’re called, because they’re taking hydrogen out dehydrogenase and they stick it out to the end. They do to make the NADH. They have a tremendous glyphosate susceptibility motif because they bind phosphate at sites with this highly conserved glycine. It’s perfect match.There was a study on E coli that looked at enzymes that were suppressed by glyphosate and there were like a dozen different dehydrogenase is that they listed that were suppressed by glyphosate. So I think life as it is suppressing the dehydrogenase is because of this glyphosate susceptibility motif, messing up the ability of the microbes to pull that guy’s gas out and to produce that wonderful NADH that’s going to be central to keeping everybody healthy.

Sinclair Kennally, CNHP, CNC

My God, Stephanie, you’re blowing my mind right now, and it makes so much sense.

Stephanie Seneff, PhD

I think so. I’m very excited about what I’m finding. That is, it’s going to be hard to get the message out because most people say, I don’t I’ve even had podcasters and I say, if you’ll let me talk about deuterium, I’ll do it. Then the day before they’ll say, what, I don’t want you to talk about it.

Sinclair Kennally, CNHP, CNC

If I can’t stand it, I don’t want you to talk about it. I know.

Stephanie Seneff, PhD

It’s tough, but it’s so fun. Once you get hooked on it, you can’t stop. I really appreciate Laszlo Boris. He sent me a note in December 2019. He basically was complimenting a paper that Greg Nigh and I had written, which we had a lot of fun writing about sulfide, glycine, messing it up and cobalamin and stuff like that. He said great paper and he said, “Oh, by the way, deuterium” basically what his message said, you know deuterium. And so that’s when I said I don’t know what’s going on with deuterium. Tell me more. Then it’s been a great relationship since then. So he and I have been exchanging emails, sharing papers, that sort of thing. It’s a difficult field. There’s very little research on it, so it’s very hard to get the information. But it exists and I’m piecing it together and I feel like I’m really making headway in understanding how the inability to supply energy with a deuterium depleted proton is really a problem if you can’t do that efficiently in the gut, your NADH is not as secure as it would have been and NADH feeds those protons into the mitochondria. So it’s a system that is really important. NADH and NADPH both of them have an age that’s going to be what I call a golden age. It’s going to be depleted in deuterium if everything’s working correctly, but because these enzymes are being messed up, it has to come from someplace else. Not as good, not as efficient. Now you’ve got more deuteriuim going into the mitochondria.

Sinclair Kennally, CNHP, CNC

So and just to remember, guys, if anybody is new to deuterium, what we’re talking about is and why this is because you must have high functioning mitochondria in order to be able to regulate at the cellular level and be able to take nutrients that arrive at the cell and actually turn them into energy. So the more you destroy the mitochondria and the more you slow them down, the more likely you are to have chronic health issues, period. Full stop, because you don’t have enough energy production. It’s not efficient enough to keep up with normal metabolic processes.

Stephanie Seneff, PhD

That’s how you can get fatigued, for example, because your mitochondria aren’t working well. Of course brain fog because of mitochondria in the brain are so important. The muscles and muscles and the brain neurons used to have lots and lots of mitochondria compared to other cells because they use a lot of energy and and mitochondrial dysfunction is connected to all kinds of diseases, including, of course, Alzheimer’s and autism, so on and even on. Other, many other diseases. Many diseases are linked to mitochondrial dysfunction. I think that’s a direct consequence of deuterium, excess deuterium in the mitochondrial water as a consequence of enzymes being disturbed by glyphosate and probably by other chemicals as well.

Sinclair Kennally, CNHP, CNC

Oh, my God. That’s so interesting. Okay. So we’ve been playing around with this in our practice from just the concept of like deuterium depleted water and how to phase that in.

Stephanie Seneff, PhD

deuterium depleted water! 

Sinclair Kennally, CNHP, CNC

This makes so much sense. So it’s really difficult to get over being sick and tired with chronic gut dysfunction. If you don’t understand this piece. I would say it’s far reaching role in it. So interesting. Any last words you want to leave our audience with on this topic?

Stephanie Seneff, PhD

Well, I just hope that people are paying attention, understanding that glyphosate is extremely toxic. I don’t want to say the other herbicides, insecticides and fungicides are not. They’re all toxic. We need to get rid of the whole idea of toxic chemicals in our food, go back to organic food generation, and we have to do sustainable, regenerative agriculture. We have to really do the research to figure out how to make it more efficient, make it more cost effective, and or we have to put a lot of people back on the farm because I think we’ve been able to free up a lot of hands to go off and do technology development and things like that, because we have so few farmers now, that’s been a benefit. I sort of feel like when countries go from being an agrarian society to being a technological society, they lose their food at that point, they start becoming toxic food exposure around the world. So as long as you have an agrarian society and many countries in Africa have got small family farms that they’re still using for food supply. Those countries are that reflected in the health of those people, because there’s very little obesity problems there. They have very little of autism. The countries that are still using the small family farms have much healthier populations than the ones that are not.

Sinclair Kennally, CNHP, CNC

Yeah, it’s so true. I mean, we’re looking at such a fragile society right now. We’re watching things collapse and fast forward, people are aging in fast forward. I know if you’re listening to this and you were like me and the first time you heard the wonderful Dr. Stephanie Seneff talk, you were really, really sick like I was. I had it because she’s so smart and she talks so fast.

Stephanie Seneff, PhD

Sorry about that.

Sinclair Kennally, CNHP, CNC

Are you kidding? It’s phenomenal. I keep hitting the pause button like, Wait, what did she just say? Because I couldn’t think fast enough to keep up with you. So right now, put your own oxygen mask on, and then as soon as start to make progress getting well, support your local farmers, get excited about learning about permaculture and regenerative agriculture. Let’s unhook from the system because you don’t need any more information honestly about the smoking gun. When Dr. Stephanie Seneff has already provided you today. We have the information she has tied it up in a bow for us. Let’s go for it then. Let’s do something with it now.

Stephanie Seneff, PhD

You’re great. Thank you.

Sinclair Kennally, CNHP, CNC

Thank you so much for being here. So appreciate your contribution. How generous you are with your information and your time. It means so much to us.

Stephanie Seneff, PhD

So thank you. I appreciate you getting it out because I really want to get this word out about deuterium and get people aware that it’s something they should be paying attention to.

Sinclair Kennally, CNHP, CNC

Yeah, absolutely. Oh, yeah. We’ll be sharing this everywhere don’t worry.

Stephanie Seneff, PhD

Wonderful. Thank you.