Full Transcript Introduction and Doctor Pfleghaaru2019s Background 0:00 Welcome back to the Bioregulator and Peptide Summit, folks. 0:02 I am so excited about my next guest. 0:05 When it comes to bridging 0:06 the gap between conventional medicine and cutting edge integrative therapies, 0:10 very few people do it as seamlessly as Doctor Jen Pfleghaar. 0:14 She's a double board 0:15 certified physician in both emergency medicine and integrative medicine, 0:19 a combination that gives her a uniquely grounded yet forward thinking 0:23 perspective on patient care. 0:25 She brings the urgency and precision of the E.R. 0:27 together with the root cause, whole body philosophy of integrative medicine, 0:31 and sprinkles in a whole lot of heart. 0:34 Doctor Pfleghaar is passionate about helping her patients 0:37 optimize their health from the inside out, 0:38 and that includes exploring some of the most exciting 0:41 and emerging tools in longevity medicine today. 0:43 Peptides and even bio regulators are very much on that list. 0:47 She's a sought 0:48 after educator and speaker known for making complex science accessible. 0:51 Whether she's talking to fellow commissions 0:53 or empowering everyday people to take charge of their own health. 0:56 We are so thrilled to have here at the Bio Regulator and Peptide Summit 1:00 to share her clinical insights and perspective on how these remarkable 1:04 bio regulators and peptides fit into a comprehensive, 1:07 personalized approach to longevity and health span. 1:10 But today, we're specifically going to talk about how she supports women 1:14 as they move through perimenopause and menopause. 1:17 Please join me in welcoming Doctor Jennifer Pfleghaar. Hi. 1:22 Thanks. Nice to see you. Thanks to see you. 1:25 Thank you so much for being here. 1:26 So, Doctor Jenny Pfleghaar please get us oriented here. 1:30 Tell us a little bit. 1:31 I mean, you started off in medicine and and then integrative medicine 1:36 so very quickly because we know we want to keep these tight. 1:39 Just help us understand how you made this transition to where you are today. 1:43 Yeah, absolutely. 1:45 So I went to medical school. 1:47 I wanted to be a do they think more whole body approach 1:51 do some on, you know, manipulation to cool stuff like that. 1:56 But I went into the emergency room and I got really disillusioned fast 2:01 with conventional medicine. 2:03 And everyone coming in had chronic illnesses that then were in emergency. 2:08 It's not like I was dealing with a lot of emergencies. 2:11 It was more chronic disease management. 2:13 So I started looking even deeper into root cause in medical school, 2:18 were kind of groomed at here's a symptom, here's a pharmaceutical agent to fix it. 2:23 So I was looking outside of that, digging into why 2:26 I went into medicine in the first place to help people dig for root causes. 2:30 And I went back and did a fellowship in integrative medicine 2:33 and never looked back. 2:35 And yeah, and then about a decade ago, I was starting my brick 2:39 and mortar practice, seeing patients 2:42 and looking for more tools in my toolbox, because that's really what it's about. 2:47 If one tool doesn't work for a specific patient 2:49 because we're all different, we need to reach for another tool. 2:52 And I stumbled upon peptides, 2:56 and then I stumbled upon actually through unit bio regulators. 3:00 And, you know, it really just opens your eyes to things. 3:04 And then, you know, in the past 5 or 6 years, we've all kind of been 3:09 turned on our heads 3:10 with all of this, with the FDA regularly regulations and changes. 3:14 And, and it's been really cool to watch the community 3:17 pivot, go to other things, go to oral agents. 3:21 So none of this is new. 3:23 The downside is it takes a lot of time to figure out. 3:27 And if one thing's taken away, where to find a good source for for it. 3:32 And yeah, I've seen a lot of great results using peptides and bio regulators 3:39 in my practice as an adjunct for lifestyle changes and diet. 3:45 So that's what I really want to say to everyone listening out there. 3:49 This is a tool in the toolbox. 3:51 This is not the 3:53 cornerstones of your health and should never be a substitute for that. 3:57 I love that that's such a powerful statement. 4:00 That's so important to say. 4:01 So let's just dive right in. 4:03 What are you finding? Like, how are you finding 4:06 that using leveraging peptides is helping your patients? 4:09 Like what are the whether it's conditions 4:11 or symptoms or imbalances that you're finding these peptides 4:15 and or bio regulators, like whatever you're bringing to the table here, 4:19 where are you finding them to be super helpful? 4:22 Yeah, absolutely. 4:23 Well, I'll just talk 4:24 a little bit about bio regulators first and then we'll dive more into peptides. 4:28 So bio regulators I've really done a lot with patients
Using Bio Regulators and Peptides in Practice 4:32 looking at their biological age and seeing what organ systems 4:36 aging faster and pairing that with a bio regulator protocol. 4:40 That's been really fun to see those results and improvements. 4:44 And then I'll also use bio regulators as an adjunct to support immune system 4:49 through thymus, to support sleep cycles of the pineal kidney. 4:53 I've seen a lot of kidney problems, 4:57 low GFR, and really supporting with the kidney bio regulator, 5:02 plus layering 5:02 and some other mitochondrial drive peptides has really like blown my mind. 5:08 Patients heading towards dialysis. 5:10 Oh yeah. 5:11 This one case study to say real quick 5:15 GFR of 5:16 30 which is like your stage two kidney disease. 5:19 She thought she would never recover. 5:22 She got the kidney disease because she was on chronic steroid use 5:26 for an autoimmune disease. 5:27 So right now we look at the whole picture. 5:29 And root causes first started with auto immune disease. 5:32 So we were trying to fix her gut health, fix her diet. 5:36 You know it's all these base pillars of health. 5:39 Fix her sleep now then we were pretty aggressive 5:43 with the kidney, bio regulator, thymus and pineal blood vessel. 5:47 I stacked those all together and then also had her on as Sasha Fiber had her on. 5:53 A nitric oxide blend of supplements. 5:56 Also introduce Motsi. Yeah. 5:59 And then and then SS 31 because those are really targeting the mitochondria. 6:04 And the kidney is so rich in mitochondrial cells 6:09 one of the richest because our kidneys are always filtering, always working. 6:13 And with this I mean over a six month progression 6:17 of using lifestyle diet, you know, exercise supplements, bio 6:23 regulators and peptides, her GFR went up to 6:26 80 and no way. Yeah 6:31 yeah it was crazy. 6:33 And we I you know I lecture on that case and she just it's amazing. 6:39 And she was like high risk you know for kidney disease diabetic 6:43 African-American like she had like all the things stacked against her. 6:47 So she did really good with that. 6:50 So that was one example of just we can use these as tools in the toolbox. 6:56 And if you're working with someone that, you know, just didn't 7:00 take a weekend course on peptides, but actually has been using it in practice 7:05 and talking with colleagues about what are you seeing, what's working? 7:09 Because the hard thing with these tools that we have, 7:13 because they're not pharmaceutical agents, you know, with big pharma companies 7:18 putting out millions of dollars in research for this, 7:22 we have to use them properly and intellectually as signaling molecules. 7:27 And, you know, we just can't put our foot on the gas pedal all the time. 7:33 You know, you'll you'll get in a wreck. 7:34 So it's really sophisticated. 7:37 But that was like an amazing case. 7:39 And then midlife we can talk a little bit more about that. 7:44 So with midlife women I mean you know I'm going through it now. 7:49 We've been through I mean, we're all in midlife, right? 7:52 Women are struggling. 7:54 So one thing women struggle with is, is sexual desire. 7:58 Right now this all goes back to stress and cortisol. 8:03 So when I work with my patients, I tell them 8:07 we need to fix the root cause of stress and cortisol. 8:11 We need to be doing parasympathetic activities by the nurse 8:14 stimulation going outside, being with nature. 8:18 Get off your phone reading, you know, all of these things. 8:22 But then we can also use a tool in the toolbox to help the situation. 8:26 So one thing is sexual desire. 8:30 In midlife, because we have fluctuating estrogen 8:34 estradiol, we had declining progesterone. 8:37 So you're just not feeling it after you put all the kids to bed. 8:42 Right now I have a teenager boy who just stays up until like 10 or 11 every night. 8:48 And I'm like, you have to go to bed, right? 8:50 I'm like, we, you know, but we'll we'll lock the door and stuff. 8:54 But anyway, so I love PT 141. 9:00 And then you can add oxytocin to that. 9:03 So let's break them down. 9:04 So PT 141 is you can get an injectable. 9:08 You can actually it's an FDA approved drug right now. 9:12 You can still get it at compounding pharmacies to injectable. 9:15 And I personally like the intranasal better. 9:20 Interesting. 9:21 Yeah. 9:21 Yeah I just feel like there's less nausea with that. 9:25 And then parents act with oxytocin. Yeah. 9:27 Because one of the side effects of the 1241 is going to be nausea. 9:33 And let's be honest, that is sometimes one of not sexy. 9:38 Yeah. Yes. 9:39 Like you don't want to. Yeah. 9:43 You don't want to do that if you're nauseous. 9:45 So that can be really helpful with doing the intranasal 9:49 I'm seeing with my patients less nausea than the injectable. 9:54 The injectable also kind of has a higher risk of 9:57 just a transient hypertension or high blood pressure. 10:02 So so that's why, you know, the injectable is fine. 10:05 But you know, sometimes I prefer the international. 10:09 So what it's doing is it's affecting 10:13 neurotransmitter transmitters a little bit in the brain. 10:16 And that is causing the hyper arousal 10:20 I like to pair it with oxytocin. 10:23 Oxytocin is the love hormone. 10:26 So that is actually a peptide that we produce. 10:29 Women think of oxytocin more with breastfeeding when it's high. 10:34 And you know if you've breastfed an infant it's just so like relaxing. 10:40 And you're just you usually nap with them. 10:43 You're calm, you're relaxed. 10:45 And we also can get oxytocin with hugging and cuddling. 10:49 So this is why we really 10:52 well it's a tool in our toolbox and we can get it synthetically. 10:55 We also need to just do things that make oxytocin secreted naturally. 11:01 And I think I was reading a study about like hugs. 11:04 And I think like, I don't know if you've read this study 11:06 now, like I think it has to be like over 30s for a hug to. Yes. 11:11 Yeah, but we don't hug people that long. 11:13 It would be creepy if we did. Right? 11:15 But strangers anyway? 11:17 Well, yeah, that's right. But like, we need to. 11:19 Even when we see each other at conferences more, we need to like, hug and like, 11:24 you know, talk and like, connect. 11:26 Be like, hey, how's it going? 11:28 You know, we just need a hug. More for 30s.
Midlife Women, Libido, and Oxytocin Support 11:30 It's like a free biohacking. 11:33 Maybe we should do that at the next conference. 11:34 Have, like 100%. 11:36 We'll have a party. Yeah, but so. 11:39 But I love using the oxytocin with the PT 41. 11:42 And I would imagine it's, it's just the tiniest amount. Right. 11:44 Because oxytocin is very powerful. 11:46 You have to be careful that you don't over do it. 11:49 And definitely this is one of those substances 11:51 that's really important to get some guidance from your medical provider for. 11:55 But I would imagine that 11:57 what it does in this situation is it gets the ball rolling. 12:01 Maybe, you know, by using a tiny amount that opens you up to this 12:05 to more physical contact with your partner. 12:09 You now get into a world where you know good begets better kind of thing. 12:14 You. Yeah, you start off with that little burst 12:17 artificially, if you will, that brings you to the place 12:20 where you're now going to produce it naturally through physical contact. 12:24 Yeah, exactly. 12:25 It's kind of like I personally like to use it during my luteal phase. 12:31 So for women, if we look at the menstrual cycle, 12:33 you have your follicular phase the first half of your cycle. 12:36 This is where estrogen is more predominant than you have ovulation. 12:40 So ovulation women we have that burst of testosterone. 12:45 We're going to be wanting to play in the bedroom with our spouse. 12:49 Right. 12:50 We're going to be ready to go because that is how God created 12:54 us, because ovulation is when we are more fertile. 12:57 And the whole purpose of our cycle is to have babies and to reproduce. 13:02 So then that then we get into the luteal phase. 13:05 So once you're mid to late luteal, I mean you're just kind of hunkering down. 13:10 You just want to watch TV or 13:13 you know, you might want to cuddle, but you might not want to be intimate. 13:16 So this is tough though because men every 24 hours their hormones are the same. 13:22 Right? 13:22 They're the same every day. 13:24 So they're always going to be wanting to be intimate. 13:27 And with marriage you. 13:29 In midlife, we see a lot of divorce. 13:32 We see a lot of struggles. It's hard. 13:34 And that's an extra stressor on women, which is not good for their health. 13:37 So really connecting intimately for spouses is is so important, 13:42 I have found, to talk about this with my patients because it could 13:47 really secure that bond in the marriage. 13:51 And it can also if there's hindrances to this, 13:55 it could also drive a wedge in between. 13:58 And really to get like ultimate health in midlife 14:02 for women that are trying to do it all unfortunately, which is a whole 14:06 nother topic, you know, making sure that bond is okay. 14:10 You know, I do ask my patients, how is your sex life? 14:12 Let's talk about it. 14:14 What what tools can we use? How can we improve? 14:16 But as you're as you said, not like this is going to help. 14:21 Just draw you in. More to that. 14:23 It's not like if you 14:25 if you don't want to do it at all, it's not going to be a magic switch. 14:28 I mean, these peptides r not like that, but it's going to get you closer to that. 14:34 Yeah. 14:34 So so using about a half an hour before is going to be helpful. 14:39 It's just it's going to bring more arousal. 14:41 The oxytocin is going to make you feel calmer and more relaxed. 14:45 And sadly a lot of people use alcohol you know, as like lubrication. 14:51 And that's not it's not good for your health at all. 14:55 And there's safer ways to do this. 14:58 You know, alcohol is a poison and oxytocin PT 141. 15:03 You know, these are signaling peptides. 15:06 So this is going to be a safer bet. 15:09 So that is something that people can think about. 15:11 And yes oxytocin. 15:13 You definitely don't want to overdo it. 15:15 If you're doing really high units of oxytocin that's going 15:19 to have negative side effects. 15:20 So I am very low and usually just do like ten units. 15:26 I'm pretty conservative when it comes to anything 15:29 supplements, medication and peptides and like start low and and go slow. 15:34 So that would be something that if you're listening out there and you haven't tried 15:38 it, it's something that you can just use, you know, PRN or as needed. 15:43 And spouses can use it too. 15:45 That's how cool is that works for boys and girls. 15:48 There aren't many things that do that. 15:50 That's so. 15:52 And do you are you also alongside this working with your patients 15:56 on maybe hormone therapy, like helping to balance hormones. 16:00 So because I just wanted to put that out there 16:02 that this is and I love the way you said this is a tool in your toolbox. 16:06 It's not going to replace all the other tools. 16:08 It's going to work with the other tools. 16:10 Yeah. 16:12 What about what other conditions are you seeing pop up 16:15 in this phase, like in Perry menopause and this transition? 16:19 That can be very challenging because of all the reasons you stated. 16:22 So yeah, we have this one pillar of physical connection, 16:25 emotional connection to your partner, which ironically, 16:28 once you reestablish that can help make everything else easier as well. 16:32 That's true. 16:33 I'm you know, I remember I think I read a paper or book 16:37 where they were talking about how being sexually active, 16:40 if you can kind of overcome the barriers through this time, it can actually, in 16:44 and of itself, also have hormone balancing effects, 16:48 like it helps support estrogen balance and things like that. 16:51 So it's one of those balls that if you can get it 16:53 rolling, might be very helpful in many different ways. 16:56 But what about things like are you seeing any impact on gut health? 17:01 Like are you finding that you're needing to dip into your toolkit 17:05 on gut health as women are moving through perimenopause as well? 17:09 Yeah, gut health, histamine shifts like that can all be a problem. 17:14 Yeah. 17:15 And it kind of goes back to to stress, especially in perimenopause. 17:19 So women might be compensating. 17:23 You know our body is very resilient. 17:25 So they might have let's say a good example 17:28 because I just have a patient on my mind that that this happened to 17:33 started just gaining massive amount of weights. 17:36 Like by the time she saw me 17:38 and I thought it would just be hormones, maybe some insulin resistance done. 17:41 Easy peasy. 17:42 She's like, no, I tried like hormones already. 17:45 So I took a good history on her and she had a mold exposure. 17:50 So she but she was like compensating. Fine. 17:53 It was all the way in college and but then she was colonized with mold. 17:57 So her body was compensating. 17:58 Compensating. 17:59 She hit perimenopause where that progesterone is declining, 18:03 declining, declining. 18:04 You did the dial spikes and progesterone 18:08 can modulate like inflammation histamine all of that. 18:13 And she just kept gaining weight. 18:16 And she was like you don't get it. 18:19 Like I'm not eating at all. 18:21 Like some days I'll only eat like 300 calories and I will gain, 18:26 you know, 5 pounds being like that. 18:28 Yeah. Her body. 18:29 So we have cortisol stressing her out. 18:32 She's inflamed and her gut health is a mess. 18:36 And then her body is just like perimenopause hit and probably Covid 18:41 played a role. 18:41 And then she was just like, her body is like, I'm out. 18:44 I am gaining all this way. 18:46 So yeah, like I'm done. 18:48 And sometimes weight gain, 18:50 its first of all, a lot of the times it's not the person's fault. 18:54 I mean, there are so many root causes for it. 18:57 Like so many times these women are like 18:59 literally eating perfect or not eating at all. 19:01 So we we treated the mold her inflammation like went away her. 19:08 She's like, I can feel my cheekbones now. 19:10 I haven't been able to for ten years and we can pair that. 19:15 So part of the gut healing. 19:16 So if we have something in the gut that is like, 19:20 you know, it's causing a ruckus, think about like if a squirrel 19:23 got in your house, right, and like went through all your cupboards and threw stuff 19:27 everywhere, it's going to cause chaos and inflammation and badness.
Gut Health, Mold, and Root Cause Weight Gain 19:32 So we can layer in. 19:34 Oral BPC 157 to calm things down, repair the gut. 19:39 We can layer in CFPB, which helps with anti-inflammatory 19:43 properties, helps with that tight junction. 19:45 I like CFPB a lot with mold patients 19:49 because when we have mold in our gut and our nose exposure to it, 19:55 it can really dampen our alpha melanocytes stimulating hormone, 19:59 which is anti-inflammatory. 20:01 So sometimes that will really just help 20:04 like take the edge off, especially if they're very sensitive mold patients. 20:08 So that was helpful with her. 20:10 So then I also layered in with her 20:13 in the specific case turns up a tide with her 20:18 because 20:19 mold can make you makes you insulin resistant. 20:23 So she was very insulin resistant because of all that she went through 20:29 with the mold, plus some hormones, plus just having all that adipose tissue. 20:34 So really gently stepping her down, her weight down. 20:39 So first lost a lot of weight with just inflammation. 20:42 Yeah. 20:43 So you just released the inflammation right. It's not even. 20:45 Yeah. Yeah. 20:46 So that was insane. 20:47 And then we worked on you know getting the adipose tissue out. 20:50 And then obviously it's always about body composition 20:54 change and not weight change when you look at GLP ones. 20:57 And we can dive into that a little bit more. 20:58 But that was kind of a cool case. 21:01 So if someone's out there listening and they're like, 21:03 or they've been listening to all of a lot of these interviews 21:06 and they're like, yeah, but like this doesn't work. 21:09 Well, there might be a root cause. 21:12 So you you have to we had to kill and remove the mold 21:16 and deal with that first so the peptides could work. 21:20 It's kind of like a delicate, you know, like just symphony almost. 21:24 And then we use peptides as tools, 21:27 as layers while we're targeting each thing. 21:30 We're not just doing all the peptides at once, being like, poof, 21:35 it's going to fix everything. 21:36 So that's that's like a specific case. 21:39 That was kind of cool. 21:40 And she like made me cry almost when she's just like, it's life changing. 21:46 So yeah, that's so great. 21:47 Well, I think what's one of the takeaways from that story, 21:50 which is a very powerful story, is that the mold exposure had been years ago. 21:55 Yeah, right. 21:55 Oh yeah. 21:56 And the the message that your body can cope 22:00 with some of these toxins for a long time. 22:02 Until the last straw. Right. 22:05 And so for her maybe exposure to Covid or, 22:09 you know, spike protein in general added an extra layer of burden. 22:13 And by the time perimenopause came around, her body had just tapped out 22:17 all of its resources and just gave up the ghost. 22:20 So I that is, you know, it's something that if somebody is feeling really stuck 22:26 in your health journey, guys, don't be afraid to go back and like, 22:30 find the physician that's going to sit with you and play detective, right? 22:35 Like, take me back. 22:37 Like, was it could have been a tick bite. 22:39 Could it have been a tick bite when you were a kid, 22:40 did you live in a moldy house? Did you? 22:43 You know, did your basements smell really musty or, 22:46 you know, whatever the case may be, that it's 22:50 your body in its magic and power dealt with it all these years, 22:55 and now it's finally hit 22:57 a wall where it's like it's outstripped your body's capacity to deal. 23:00 And that that that is really amazing. 23:03 And and you know what? 23:04 I keep hearing from you and other physicians on this summit is how, 23:10 look, you 23:11 used to treat people without peptides and bio regulators in the past, 23:14 but what's happened with them is it seems to have kind of shortened 23:19 the distance between identifying an issue and helping 23:24 your patients to get to resolution and see the results that they want to see. 23:28 Yeah, it's such a good tool, such a good adjunct. 23:32 And, you know, when you work on the pillars of health 23:35 that once you get those habits, once 23:38 you really make sure you identify where you're not getting good sleep or why. 23:43 And you know, your nutrition, your movement, your breathwork and prayer 23:46 life, then the peptides only just will build on to that 23:50 and then you'll just keep soaring. 23:52 You won't need to be spending money on peptides forever, or 23:56 you just add them on for fun or for longevity purposes. 24:00 So I think that should be the goal with peptides not looking at them, 24:04 you know, as a it's going to fix everything. 24:07 It might for a short time. 24:08 But if you're not working with someone or working on the pillars in general, 24:13 and this is why, 24:14 this is why peptides in the last couple of years have been the Wild West, 24:17 because everyone's looking at it as a fix all for everything 24:21 and everything will be okay. 24:23 And that brings us to like the GLP ones in weight loss. 24:26 Yeah, everyone is so desperate to lose weight. 24:29 And a lot of these women especially, I mean, they're looking at people getting, 24:35 you know, like 24:37 like cocaine thing, you know, like how it used to be cool in the 90s. 24:41 Right. 24:42 And you know, they want that because they've wanted that since they were, 24:48 you know, in high school because that's how women looked back then. 24:52 And then they're getting it and they're getting all sorts of problems, 24:56 like having to get their gallbladder removed or being weak, you know? 25:00 And then I worry about these women as they cross over to menopause. 25:05 And if they're not, they don't have basis of like proper, 25:09 you know, hormone replacement and stuff like that. 25:12 They're not going to have muscle 25:13 to support their bones and they're going to break a hip. 25:16 And then if you break 25:17 a hip and end up in the hospital, your mortality rate is super high. 25:21 Yeah. 25:21 So with with the GLP ones, I really go through a lot of counseling 25:26 with my patients on it about how this is about body composition change. 25:31 It's not about just losing weight. 25:34 They have to lift weights. 25:36 Three like I have non-negotiables. 25:38 I'm like, you have to lift weights three days a week. 25:40 I do I'm kind of mean about it. 25:42 I can't imagine you being mean about anything. 25:44 Okay, I'm not mean, but I'm like, this is what you have to do. 25:48 Yes, yes. Yeah. 25:49 I mean, yeah, not me, but, you know, live three days 25:52 a week, have 120g of protein a day. 25:55 If you don't feel like eating or drinking, then you know we're going to dial back. 26:00 You know, this is slow and steady, wins the race. 26:03 All the things like, you know, you don't want to look like that person 26:06 on Facebook that lost 50 pounds in three months. 26:09 And you're like people. And then people come at you look good. 26:12 It's like, no, like, well, here's the thing, 26:15 GLP ones, they are modulating inflammatory cytokines. 26:20 We do know that they decrease inflammatory cytokines. 26:23 So those people might actually look good because they're less inflamed. 26:27 But if they have saggy skin, if they have no muscle then they're doing it wrong.
GLP-1s, Muscle Preservation, and Longevity 26:33 They're on too high of dosing. 26:35 They're not doing the habits that are really going to make it work 26:40 the way it's supposed to. 26:41 And this is and that I would love to know what you think. 26:44 I think it's like it's such a beautiful peptide that we've been using 26:48 before, big pharma, the Kardashians really pushed it. 26:52 And I just it's getting pushed too hard, too much, too long. 26:57 And we have diabetics that are still eating donuts 27:01 for breakfast, but they're on a GLP one. 27:03 And we're going to see positive results because it's modulating inflammatory 27:07 cytokines that, you know, inflammation is what causes, you know, 27:10 the heart disease and it is helping there fasting blood sugar. 27:15 But I mean, we're just in a mess right now. 27:17 It's crazy. 27:18 Yeah. 27:18 I think what they're sacrificing is their longevity and health span. 27:22 Right. 27:22 Because if you're not nourishing the body 27:26 at a micronutrient level in terms 27:28 of what it needs, if you're not giving it the materials that it needs to build 27:32 healthy bones, build healthy, maintain enough muscle 27:36 that you can retain your independence, right? 27:39 And feed your brain and all of the other things that we know we need to do. 27:43 If if all you're doing is looking thinner but not 27:46 taking care of the rest of the house, it's the long 27:50 term results that I think is going to be the most concerning. 27:53 So the nice thing I think for 27:56 the Globes is it's a little bit like we talked about with the oxytocin. 28:00 They give you a leg up right. 28:01 They give you that kickstart. 28:03 They give you the opportunity to change your diet 28:05 and improve your lifestyle and all that stuff. 28:08 But it's about working with a coach or a physician and like, 28:12 you know, you get your prescription from your physician. 28:14 If your physician doesn't do what doctor does, 28:17 which is to actually coach for clients, then find yourself 28:20 a coach who can help you, who could then support you in the day to day 28:25 so that you're not sacrificing the long term for the short term gain. 28:29 Yeah. 28:30 And then sometimes with a GLP one I will add in a growth hormone secreta Gog. 28:36 So those can also be helpful in in midlife. 28:39 And this is like a Moreland CJC 1295 Sarah Moreland. 28:44 So we can layer those in. 28:47 And growth hormone secreta dogs. 28:49 It's not giving growth hormone right. 28:52 I mean you can get those online where you're giving yourself growth hormone. 28:56 But then yeah but then we run the risk of, you know, our skull 29:00 growing, our hands growing. 29:02 I always think of Barry Bonds. 29:03 I don't know if you like. 29:05 I was really into Pittsburgh Pirates baseball. 29:07 And like, I remember there was like the growth hormone scandal with him. 29:10 And anyway, 29:11 that name always comes up in my head 29:13 where I'm like, we're not giving growth hormone. 29:15 But but sometimes that can that can help. 29:18 It can stimulate appetite a little bit, help with that lean muscle 29:23 because we know that GLP ones can decrease muscle okay. 29:29 And and fat, but both at the same time. 29:31 So sometimes layering that growth hormone secreta Gog. 29:34 And I know we're talking about midlife women but men respond 29:37 really well to these. 29:39 I have a male patient that he 29:42 he like is so tight about his weight. 29:45 Like he did the HC diet for year. No. 29:49 Yes. And I'm like no more. 29:51 So we we have a monstrous appetite CJC Upper Moreland. 29:55 And then his testosterone is optimized and he's doing great 29:59 and same thing I had to be firm with him. 30:03 And I'm like why aren't you lifting heavier weights. 30:06 Because I went through his weightlifting routine and I don't know, but 30:10 like so many people, just won't lift heavy weights. 30:13 And I like, have to like, write it like as an order. 30:17 Right? I have to be like, I am making, you know. 30:19 So I mean, if I could go to their house and, like, stare through the window 30:23 and be like, lift weights, I would but but he had great results. 30:27 So he lifted weights and did the growth hormone secreta 30:32 gog and gained 10 pounds in muscle like over three months. 30:36 And I was like, this is actually crazy because he had the building blocks. 30:39 Like his lifestyle is dialed in. 30:41 He had optimal testosterone. 30:43 He was using the tours appetite because he to help his hunger cues, 30:48 because that was an issue for him overeating. 30:50 And then he had the growth hormone secreted. 30:52 So it was pretty layered. 30:54 And then for me, growth hormone secreta God, 30:56 I let patients use it for 2 to 3 months and then we take a break. 31:01 We check IGF one levels. 31:02 So once again like when we look at the bodybuilders, 31:06 when we look at the people that are, 31:09 you know, on peptides and all the gym bros pushing 31:11 all these peptides, we don't know what's going on inside of their body. 31:15 They could be pushing these pathways, mTOR pathways, IGF one to hard. 31:20 And we know bodybuilders in general have a shorter lifespan. 31:24 So it goes back to what you were saying at about like, 31:27 what are we sacrificing here to have a perfect body, 31:31 to look really lean all the time and have our blood vessels pop in and, 31:37 you know, like, I don't know, I just don't think that is worth 31:41 risking our longevity for me, looking perfect right 31:45 now, trading that for time with my grandchildren in the future. 31:49 So I think that everything's a balance. 31:53 This is my problem sometimes that I'm too 31:56 in the middle, like I'm not extreme. 31:59 But anyway, I mean, I just my fear is that watching these conversations 32:04 on Facebook, I joined a group on like, you know, peptide users. 32:10 And it is horrifying. 32:11 People are showing these 32:13 like files that are brown and they're like, should I use these? 32:16 And I'm like, this is so scary. 32:18 This is so sketchy because they're not getting them 32:20 from compounding pharmacies, and they're not working with someone 32:24 that knows what they're doing. 32:25 And I'm like, are you willing? 32:27 You know, this is just like trying to trade short 32:31 term fulfillment in joy for or not even joy. 32:36 Just, I don't know, like self-gratification for future, 32:40 you know, treasures. 32:42 Yeah. And yeah. 32:43 So we have to be careful about that. 32:45 And that's why I wanted to share a bunch of stories about how patients 32:49 with it done, how sophisticated peptides 32:52 and bio regulators can be, and that it's 32:55 it takes a little bit of time, you know, and it's it's thoughtfulness.
Final Advice and Where to Find Doctor Pfleghaar 33:00 And and now you've been in this space 33:03 for well you're the OG. So 33:07 so you know you know how it is. 33:09 Yeah. Yeah. Well thank you for that. 33:11 I mean I think I'm, you know, one of many people, but it's 33:14 definitely it's, it's we've definitely moved into a new phase. 33:18 But having said that, that's what the summit is all about 33:20 is helping people to connect with people like you, practitioners and physicians 33:24 like you, who bring a nuanced approach to the space, which I think is lacking. 33:29 So as we close up, are there any final thoughts 33:33 you'd like to leave the audience with? 33:34 And after that, let's tell them where to find you, 33:37 where to find your beautiful book, and how to connect with you 33:41 if they're looking for some support. 33:44 Yeah, absolutely. 33:45 I would say to those listening out there, just really focus on your pillars 33:51 of health before you get ready to dive into the peptide world. 33:56 Just take a little bit, take a step back and just do a little inventory 34:02 of the pillars of health, like where is your sleep at? 34:07 Where is your meditation prayer breathwork life? 34:12 That where is your food at? 34:14 Where's your exercise at? 34:15 So do a little inventory, see what you can tweak 34:18 and then maybe add on or bio regulators. 34:21 So I would I would say just take a step back or if you're like, 34:25 I need some something to get me over this home. 34:28 You know, even like we talked about PT 141 and oxytocin. 34:32 Like you need something for that. Hum. 34:33 Yes. That's fine. 34:35 Like add 1 or 2 in, but just do an inventory before you start 34:39 rushing into everything, because it's so fascinating 34:43 and it's so attractive to just like, yes, I want to use everything. 34:47 These are all so cool, but just take it slow. 34:50 I would say just take it slow. Beautiful. 34:52 Thank you. 34:53 Where can people connect with you? Yes. 34:55 So I am on Instagram at Integrative 34:59 Doctor Mom, Integrative drmom and YouTube. 35:02 I have lots of free content there and then my website is Healthy 35:07 by Doctor Jen, healthy by Dr. 35:10 J e n And lots of free resources 35:14 downloads there that could help you in your health journey. 35:18 Thank you so much, Doctor Pfleghaar. 35:20 It's always a pleasure. Thank you, thank
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