Full Transcript Summit Introduction and Doctor Gupta's Background 0:00 Welcome everybody and Doctor Gupta to the Peptide and Bioregulator Summit. 0:05 Or maybe it's the Bioregulator and Peptide 0:07 Summit is the way I'm naming it because bioregulators are my fascination. 0:10 Now a little bit about Doctor Gupta is that he's dedicated his career 0:15 really to solving one of the most misunderstood 0:18 conditions in modern medicine, and that is thyroid disease. 0:21 He's a board certified family medicine physician, a certified functional medicine 0:25 practitioner through the Institute of Functional Medicine, 0:28 and he also holds a fellowship in integrative medicine. 0:31 So he this is a man who carries advanced certification, also in peptide 0:36 therapy through the American Academy of Anti-Aging medicine. 0:39 So the man knows of what he speaks. 0:41 Let's just be clear. 0:42 He trained and practiced at one of the most 0:44 respected institutions in the world, the Cleveland Clinic Center for Functional 0:48 Medicine, where he worked alongside the pioneering doctor Mark Hyman. 0:52 And that experience shaped a clinical philosophy rooted not in managing symptoms 0:57 but in uncovering and reversing the root causes of disease, which all of us 1:01 who are here know is the key to getting lasting results. 1:05 He's also the best selling author of Reversing Hashimoto's. 1:08 This is a book that's changed the way of patients 1:12 and practitioners understand autoimmune thyroid disease. 1:15 And through his practice, his online education, and his growing community, 1:20 he's become globally recognized as the world's Hashimoto's expert. 1:24 So today he joins us for the bio regulator and Peptide Summit. 1:27 I'm so grateful to talk about the deep connection between thyroid health, 1:31 immune function and the emerging role of peptides and bio regulators in helping 1:35 patients truly heal, not just manage this crazy condition. 1:40 Please welcome with me, doctor Angel Gupta. 1:43 Welcome. 1:45 Thank you so much for having me over here. 1:46 You know, that was a very generous introduction that you did. 1:49 And I am really grateful for that. 1:51 And so great that you were putting up this summit, 1:54 you know, with so many great speakers and talking about different facets of, 1:58 you know, peptides and bio regulators. 2:00 And we were just discussing before this interviews that, you know, 2:03 this is a current time, 2:04 you know, where the peptides and bio regulators are getting so popular. 2:08 And this is the right time for people to know about them so they can utilize, 2:12 you know, the health benefits of them. 2:13 So finally, we are getting heard 2:15 and they are getting available to majority of the people. 2:18 So thank you for putting up this summit. 2:20 Well, it's my pleasure. 2:21 You know, I think big motivation for me of putting this summit together 2:25 is how much misinformation is out there. 2:28 And as the, you know, as this space grows and there's so much confusion around 2:34 how to use peptides and bio regulators properly in practice, 2:38 not just sourcing them 2:39 from some crazy website online and experimenting on yourself. 2:43 I think it's just it's really raised the bar on how badly 2:47 the education is needed and how badly people need to understand 2:50 who are the practitioners and and medical doctors who really are able 2:55 to who've studied this, who've done it in clinical practice, who are really able to 2:59 guide them? 2:59 Because the thing about peptides and bio regulators is there incredibly powerful. 3:03 But if you don't use them at the right time, in the right way, 3:06 particularly with these complex conditions, 3:10 at best you don't get any results. 3:12 At worst, you might get worse results. 3:14 So this is where your wisdom and experience really comes into play. 3:18 So I'm really excited for this conversation. 3:20 So let's start with our opening question, which is often a question I start with 3:24 with people like you. Is that what? 3:26 Was there a turning point in your clinical work 3:29 that really changed how you viewed Hashimoto's? 3:33 Absolutely. 3:33 So I think, you know, like we all, you know, as functional medicine provider, 3:37 do not go into functional medicine or alternative medicine just because, 3:40 you know, like we got interested. 3:42 Something happens in our own life. 3:43 It kind of, you know, propels us into that direction. 3:46 So I was a busy family medicine practitioner. 3:48 After my residency, I was working in my private clinic. 3:52 Within a few years, you know, 3:53 I started noticing certain things were creeping up in my life. 3:56 I was having health issues. 3:58 A lot of weight gain was happening. 3:59 A lot of gut related problems were experiencing random stomach pain. 4:04 No idea what the pain was going on. 4:06 Why was the pain coming to me? 4:08 Plus, you know, I was feeling tired during the afternoon 4:11 time to the point that I was taking naps during my lunch hour. 4:14 Just a function of the whole day, and I was feeling brain
Hashimoto's Turning Point and Root-Cause Approach 4:17 foggy at the end of the day, feeling that, okay, well, 4:18 I cannot just think about anything more than just going to bed or relaxing. 4:23 So then, you know, like initially I thought maybe it is stomach acid, 4:26 you know, because I'm stressed out. 4:27 Let me just start with, you know, like the over-the-counter medications. 4:30 Try that. 4:31 You know, increasing the dose of medicine. 4:33 PPIs were added. 4:35 Nothing was working. What was going on with me? 4:37 They added even more medications. 4:39 At one point of time, I was taking five different medications 4:42 just to function to the day, but still, you know, weight, krypton creeping up. 4:47 You know, 4:47 the fatigue was relentless and things 4:49 the stomach pain was still happening 4:50 randomly. So then somebody suggested, well, 4:53 why don't you look into this functional medicine? 4:55 Because, you know, this is where people go who do not get answers from. 4:59 So I started trained into functional medicine. 5:01 I kind of did a couple of modules with them 5:03 and started implementing those things in my life, change some things in my diet, 5:07 you know, it's from, 5:08 you know, de-stressing 5:09 in my regular routine and just some added some basic supplements. 5:13 And within one month of doing that, I saw great results. 5:16 My stomach pain went away completely, and then within six months 5:19 I was off all of those medications I lost pounds. 5:23 Managing was so high that even participated in a rugged maniac. 5:28 So that's where I thought, well, I need to do functional medicine, 5:30 you know, help more people like me because there were several of them. 5:33 So when I joined this functional medicine center 5:35 at the Cleveland Clinic, and I started kind of noticing that I was attracting 5:39 the subset of people, they were all middle aged females. 5:43 They're very similar symptoms as mine. 5:45 They were all gaining weight. They were all tired. 5:48 They had brain fog, gut problems. 5:50 And one thing was common 5:52 that they all had Hashimoto's or thyroid problems going on. 5:55 So that's where that intrigued me. 5:57 That okay, well, simply connected with those people. 5:59 And I started looking the research of what is the root cause of their issues. 6:03 So slowly and slowly I developed this three step process, which I started 6:07 implementing in my own clients over there, and we saw great results. 6:10 And this was huge 6:11 because in my medical practice, I was told that there is no medication out there. 6:15 There is nothing out there that can actually reverse a disease 6:18 where you can actually lower the thyroid antibodies. 6:21 So that was very promising for me. 6:23 And that's where prompted me 6:24 to start working in Hashimoto's clients and helping them out. 6:28 And that's 6:29 what I've been doing for the last 7 to 8 years, implementing this process. 6:33 And, you know, getting the life back for all of these Hoshi patients. 6:37 That's amazing. 6:38 That's a great story. 6:39 Now, you mentioned the the antibodies. 6:42 So this is really a pivotal point in your practice where you often say 6:46 that Hashimoto's is autoimmune first and thyroid second, 6:50 which is which is interesting because it's not just the thyroid antibodies. 6:53 Now you're talking about the immune system misfiring somehow. 6:58 What do you want 6:58 clinicians and patients to really understand about this distinction? 7:01 This this approaching thyroid issues from an immune system perspective. 7:06 So again, you know, like in every medical college out there. 7:10 The only treatment that we have been told that a person comes up with a tire 7:15 problem is give them with rocks in medicine. 7:18 Yeah. 7:18 And you know, because they have low thyroid hormone 7:20 give the levothyroxine everything is solved. 7:22 Well, nobody is even talking about why a person has this hypothyroidism, 7:27 which is this total immune dysregulation which is happening in a person's body. 7:32 And until we saw this immune dysregulation, 7:35 their body is not going to get better. 7:37 And this is where again, research proves us, 7:39 because research says around 60 to 70% of people 7:42 who are taking thyroid medications there is within normal range. 7:46 But still they continue to have symptoms. 7:49 So that clearly tells us that 7:51 the current treatment is not appropriate or not enough for majority of the people, 7:55 and that is because of the underlying immune dysregulation. 7:58 Now, most people think that this underlying 7:59 immune dysregulation is only damaging the thyroid. 8:02 My research suggests it is a systemic problem and not a tired problem. 8:07 This immune system, you know, damages your mitochondria. 8:10 Damaging your adrenals, damages your brain, damages your gut cells. 8:14 Multiple places in your body are being damaged. 8:16 And that's the reason the symptoms that Hashimoto's or low 8:20 thyroid comes up with is system wide. 8:23 And again, replacing the thyroid hormone doesn't solve them because we are not 8:27 working on the actual problem of the underlying auto immunity. 8:30 Yeah, yeah. 8:31 That's so powerful. 8:33 So what do you see. 8:35 So that you talk about triggers in patients. Right. 8:37 So there are very common triggers that are involved. 8:41 Both either I don't know if they're the same ones, but in the Hashimoto's. 8:45 And we also have graves disease. Right. 8:46 We have to remember this 8:48 is there's two sides to this coin of thyroid imbalances 8:52 if we want to call it, if we don't even want 8:53 to give the label of disease, we're going to call them. 8:56 You know, there's two sides to the coin of a thyroid imbalance. 9:00 So where do you what do you what are you seeing as the major triggers? 9:04 I think there's maybe 4 or 5 that you really talk about quite a lot, 9:07 which I think is really interesting for people to really understand. 9:11 Absolutely. 9:12 So first of all, like understanding that 9:13 what is auto moon disease is because again, most people 9:16 when they go to their doctors and ask, why did I get this a cease? 9:19 And they will just say, well, you know, like today 9:21 your body decided to start making these antibodies. 9:24 Just like that is not real. 9:25 The research again gives us answers over here. 9:28 It says that auto immune diseases, whether it is Graves or Hashimoto's, 9:32 is an interlink between the environmental factors and your genetic makeup. 9:38 Now again, I want to wash over here as soon as a word use genetic makeup. 9:41 People think, oh, that means it is in my jeans. 9:44 So it is hereditary, so I cannot do anything about it that is not real. 9:48 You know, yes, you do have a pool of genes, 9:50 but why are we seeing a big increase? 9:54 You know, exponential increase in automation diseases 9:56 is an environmental factor. 9:57 And those are the triggers that when our genetic pool 10:01 get exposed to that further leads to producing of these antibodies. 10:04 And these are the triggers. It is very important to identify those. 10:07 Then only you can work on them. 10:09 So typical triggers that I see is first of all there's food sensitivities. 10:13 Now our food again has been changing at a very rapid rate. 10:16 The whole processing of the food that is happening, the whole food 10:20 that we are using in terms of, you know, insecticide, pesticide 10:23 or the GM crops is changing our food from what it was before. 10:27 And one of the foods which has rapidly change is wheat or gluten. 10:31 So we are seeing more and more people, you know, being sensitive to gluten. 10:35 Similarly, there are other foods, you know, which can be sore. 10:38 Sometimes it can be dairy, which can be processed food. 10:41 And these food sensitivities, 10:43 you know, basically damages our gut and leads to this leaky gut, 10:47 which is, again, you know, and starting point for Hashimoto's or Graves disease.
Autoimmune Thyroid Disease and Major Triggers 10:51 So full sensitivity being number one, where, you know, poor quality of food 10:55 is causing to having reactions to and triggering of Hashimoto's sees. 11:00 The second one we're dealing with is nutritional deficiencies. 11:04 Now your thyroid needs specific nutrients, specifically minerals 11:08 like zinc, like selenium, magnesium. 11:11 It needs vitamins like vitamin D, vitamin, you know, bees. 11:14 And unfortunately, our current diet, you know, our current food 11:18 is low in these vitamins and minerals. 11:20 Even though people are eating a healthier diet, our soil itself is low 11:24 in these vitamins and minerals, which are very important for our gland. 11:28 So once we don't get those again, that leads to triggering of Hashimoto's. 11:32 So that's the second trigger that I see very often. 11:35 The third trigger over here is stress. 11:38 Now this is the stress. 11:40 You know, it can be emotional stress. 11:42 It can be super stress or it can be hormonal stress. 11:45 That's the reason I see a lot of females 11:47 being diagnosed with Hashimoto's sees after they are gone through a pregnancy, 11:51 because pregnancy again is a big shift in hormones. 11:54 So post pregnancy 11:55 the protective hormones go away and again Hashimoto's gets triggered. 11:59 Similar thing happens in menopause. 12:01 Again, big hormonal shifts. 12:03 So that's the reason females are a little bit 12:04 more prone to Hashimoto's because of big hormonal shifts. 12:08 But the world is more stressful than it was before, 12:11 so definitely all can experience that on the daily life of our. 12:15 So again, that is a big trigger that we are experiencing. 12:18 The next over here is toxins and I can name at least 100 12:23 toxins, you know, which is there in our environment 12:25 which has been associated with autoimmune diseases. 12:27 And unfortunately we are pouring more and more whether it is heavy metals 12:32 like lead, mercury, we already knew, like, you know, decades ago that there 12:35 damaging our body. 12:37 You know, whether it is a mole toxins which just recently in the last 5 12:40 or 7 years ago that we can notice that they are damaging a land 12:45 or the environmental toxins, whether it's a glycosides from roundup, whether it is, 12:49 you know, insecticide, pesticide, plastics, all of those things accumulate 12:53 in our thyroid gland and again lead to triggering of Hashimoto's disease. 12:57 So that's a fourth trigger. 12:58 And the fifth trigger over here is infections. 13:01 Whether it is parasites in the gut like blastocyst, 13:04 whether it is bad bacteria in the gut which is the sibu 13:07 overgrowth of bad bacteria, or overgrowth of Candida in our gut, 13:11 or are we dealing with Epstein-Barr virus reactivation? 13:15 Or recently we are seeing that post-Covid. 13:17 Also, more and more people are being diagnosed with Hashimoto's. 13:21 So these again, chronic infections, reactivation 13:24 of those again can lead to Hashimoto's. 13:27 So these are five big triggers 13:30 which a person can get exposed to and that can lead to Hashimoto's. 13:34 But more importantly most people have to understand it is never just one trigger. 13:38 It's a combination of 2 to 3 triggers coming together, and then your body's 13:44 immune system gets broken down and that ultimately causes 13:47 this autoimmune disease function. Yeah. 13:49 And that really you know, this is so clearly building the case 13:54 and highlighting why just throwing thyroid hormone in someone is just not. 13:59 It's so often it's just not going to move the needle for them. 14:02 It explains why so many people have been written prescriptions 14:05 for thyroid hormones and they just don't feel any better. 14:08 And as you said, you know, they often just get gaslit 14:11 by their doctors who aren't doing it to be mean. 14:15 It's, you know, it's what they know. 14:16 They're like, well, dude, I did what I could. 14:18 This is what I've got, go forth and feel better kind of thing. 14:23 It's disappointing. 14:23 But the beauty of people like you who are out educating people like 14:27 this is really helping to empower the the patient to say, I'm not crazy. 14:33 There's more to it than just one thing. 14:35 And giving them this actionable, actionable 14:38 playbook to really address this stuff. 14:41 And and, you know, 14:42 you mentioned gut permeability, which is, you know, it's prevalent in society. 14:47 And so when we talk about people having a permeable gut and, 14:50 and really activating their immune system, it could go any which way. 14:55 And for whatever reason, 14:56 there's a population of people where it goes after the thyroid, which is. 14:59 So it's interesting and maybe for another discussion. 15:02 But but there's other issues in the gut that can be a factor, I think. 15:06 And what are your thoughts on the role that an H. 15:09 Pylori or candida overgrowth might be playing, 15:12 or maybe even like broader dysbiosis, like kind of a gut microbiome 15:18 imbalance, major imbalance going deeper into the gut. 15:21 Right. 15:21 So the H pylori will be more in, in the upper digestive tract. 15:25 And then the Candida or Candida can be anywhere. 15:27 But but what are your thoughts on those other players in this area. 15:32 Absolutely. 15:33 So again gut related infections are so common. 15:36 And again, you know, like anything or everything that, 15:38 you know, all these triggers, you know, have research behind it. 15:41 So it's not that me just kind of making up, you know, like 15:43 okay well today this is a trigger that your body is going through. 15:46 So we have associations which the research studies have shown. 15:49 Similarly H pylori also we have association that it can trigger 15:52 Hashimoto's. And again treatment of H. 15:56 I can actually help people in lowering the antibodies. 15:58 Similar thing you know has happened with parasites in the gut and things also. 16:02 Now what is association and how does the actually play a role. 16:05 So again it is multifactorial. 16:07 First of all, whenever you get an infection in your body, 16:10 what it does is that your body is immune system, 16:13 you know, is trying to fight off with that infection. 16:15 And these infections are not acute 16:17 infections where let's say you get a strep infection 16:19 and if you don't do anything about it, you're going to land up in the 16:21 emergency room and everybody will know that you had a strep infection, 16:25 as in fact not parasites can go undetected for a very, very long time. 16:30 So basically, 16:31 like your body's immune system is so busy in trying to fight them off. 16:35 And sometimes our body's immune system gets defeated. 16:37 And that's where, you know, like, you know, this gut permeability happens. 16:41 That's the way, you know, the damage 16:43 which starts happening because it leads to chronic inflammation in your system. 16:47 And chronic inflammation is basically, again, your body damaging itself. 16:52 And that ultimately, you know, like triggers 16:54 leading to these autoimmune processes, which is happening now. 16:57 Interestingly, some of these things like Candida and other things, 17:00 they also play something called molecular mimicry. 17:03 What that means is that the genetic makeup or some of the cellular 17:07 makeup of these organisms 17:09 are very similar to some of the cellular makeup of thyroid gland. 17:13 So when your body's defense system is trying to kill 17:16 or get rid of these organisms in friendly fire, 17:19 unfortunately they also damage your thyroid cells. 17:23 And just imagine this friendly fire is happening each and every day, 17:27 3 or 30 days of the month, 365 days of the year. 17:30 Ultimately, yes, your thyroid does get damaged 17:33 and unfortunately you're not seeing any symptoms, right? 17:36 Because a lot of people come to see me. 17:37 My gut is perfectly fine. 17:39 I'm going to the restroom every day. 17:41 I'm pooping every day. 17:42 No problems. 17:43 I said, okay, let's do advanced analysis. 17:45 And sometimes, yes, we do see us over there. 17:48 Sometimes we see overgrowth of bacteria, sometimes we candida. 17:51 So that's the problem with these chronic infections. 17:54 They don't give overt symptoms in a lot of people. 17:57 So they never know that is what is going on inside their body. 18:00 Yeah. 18:01 So that really 18:02 was leading into my next question, which is what labs do you consider. 18:05 And people, if you're getting impatient here 18:08 because we haven't even said the word 18:09 bio regulator or peptide yet, just know we're getting there. 18:12 We're just we're laying we're laying down the education. 18:15 And this is the point I want to make 18:17 about peptides and bio regulators is they're not your first place to go. 18:21 So we need to understand the situation. 18:24 You need to understand the drivers. 18:25 We need to understand what's happening. 18:27 And then we need to understand when to bring these small powerful molecules in. 18:32 So be patient. We are getting there. 18:34 We will be there in just a couple of minutes. 18:36 But going back to the question you just mentioned assessing gut health. 18:40 What other than gut health labs or maybe share with us some of the lives 18:44 like what are the labs that you really consider essential when you're evaluating 18:48 a patient and you're suspecting thyroid dysfunction or Hashimoto's. 18:53 So first of all, going to the basics in terms of what labs 18:56 everybody should be getting. 18:57 So again, you know, once a person goes to the regular doctor, the only lab 19:00 they get is TS, which is a thyroid hormone. 19:04 That is definitely an inadequate way, not a complete way 19:08 of evaluating your thyroid gland. 19:09 So along with your TS, you need to check your actual 19:12 thyroid hormones, which are your free T3 and your free T4, 19:16 so that you can actually know how much of the thyroid hormone 19:19 is reaching your cells. 19:21 Because in some people, the T4, which is an inactive thyroid hormone, 19:24 doesn't get converted into the active thyroid hormone, which is the T3. 19:28 So you need to know what is going on over there. 19:30 Plus then you need to get your antibody levels checked. 19:33 Let's say you're, you know, assuming you have hypothyroidism then 19:36 two antibodies are TPO antibody which is a thyroid peroxidase antibody. 19:40 And the second one is the thyroid globulin antibodies. 19:44 Again these two antibodies can easily be done with any lab across the nation. 19:48 And same blood work. 19:50 You know when you're drawing you know for TS you can get these done. 19:53 So these are at least the basic labs at each and every thyroid. 19:57 Patients should be getting to complete evaluation. 19:59 Now after this, 20:00 if your practitioner is ready to order a reverse T3 lab, that will again 20:05 be very useful because then you will know that you know whether it is actual 20:10 problem is a low T3 or the reverse T3, because there are two separate things. 20:14 T3 is actual thyroid hormone which is have a positive effect on your body. 20:18 Unfortunately, your body as something called reverse T3, 20:22 which is the brake hormone, which is an anti thyroid hormone, 20:26 which doesn't let your T3 hormone to work on your body. 20:29 In some people, T3 levels are perfectly fine, but the reverse T3 20:32 skyrocket high. 20:33 So the problem is not give to more thyroid hormone. 20:36 The problem is actually lowering or working on this reverse T3 20:40 so that the actual thyroid hormone medicine can work better. 20:43 So these are the basic labs. 20:45 Then on top of that to know your root causes, you know, getting an advanced gut 20:49 analysis like a map or a GIF is very important to know 20:53 what is going on inside the cut. Do you have leaky gut? 20:55 Do you have bad bacteria? Do you have Candida? 20:58 Do you have pylori going on or do you have any other infections going on? 21:02 Then after that, looking at your toxins, doing a heavy metal test or a mole 21:06 toxin test or an environmental toxins test to know the total toxin burden, 21:11 because what people don't realize is that we only have one detox system. 21:15 All the toxins have to go through that one system. 21:18 So let's say you have a little bit of mercury, 21:19 a little bit of lead, a little bit of, 21:21 you know, mycotoxins, a little bit of, you know as well. 21:25 Now when you combine all of them that becomes significant. 21:28 So you need to know your total toxin burden. 21:31 Then after that, if you suspect that you might have 21:34 underlying Epstein-Barr virus reactivation, you can do that. 21:37 Or now these days you can also do 21:39 your Covid antibodies to kind of see if they're really very high or not. 21:43 And then after that, looking at your vitamin and mineral analysis, you know, 21:47 where is your selenium levels, where is your zinc levels, 21:49 where is your magnesium levels, you know, where is your vitamin C, vitamin 21:53 E levels. 21:54 So those, you know, can be known about it. 21:57 So these are the basic things that I will say that people should get. 22:00 Yeah yeah yeah 22:01 I was just wondering like what role do you think iodine plays in all this. 22:04 Because I haven't heard you mention it yet. 22:06 And yet iodine you know, is so we understand is so central
Gut Infections, Lab Testing, and Key Nutrients 22:11 to thyroid health. 22:13 So many people now are deficient and and maybe even as we've moved towards 22:18 these better salts and steak come away from iodized salt. 22:23 What are your thoughts on iodine. 22:25 And maybe even something like selenium, which is another one of these trace 22:28 minerals that is just, you know, there's a very sweet spot for selenium. 22:32 You don't want to go up, you don't want to go too high or too low. 22:35 Same with iodine. 22:36 So the reason I did not mention iodine is this is one of the most 22:40 controversial things in the thyroid. Yeah. 22:43 About the future I know. 22:45 So there are two camps. 22:46 One camp loves iodine. 22:48 They want people to have very, very high doses of iodine 22:51 because the claim is that, you know, that, you know, rebalances your thyroid. 22:54 It is also anti infective. 22:57 So that kind of clears up all the like, you know, 22:59 all the infections and everything in there. 23:00 But on the other hand there are people who say that no no no. 23:03 Do not even touch iodine because that is going to flare up Hashimoto's disease. 23:07 So remove every bit of iodine from your diet or from really? 23:11 But don't you need iodine for T3 and T4? 23:14 Like that's what the three and the four. 23:16 It's the number of iodine molecules attached to the central molecule. 23:21 That is exactly correct. 23:22 So the research is very clear over here is that when you have 23:26 very high doses of iodine, that is going to cause Hashimoto's sees, 23:30 when you do not have any iodine, you are going to get Hashimoto's. 23:34 So there is a sweet spot, you know, like, you know, you need to hit. 23:38 Unfortunately, we do not have a perfect blood test to check for iodine levels. 23:42 So that's the reason, you know, it's not very common to check it. 23:45 And there is no way to know your iodine levels. 23:47 We do have a urine iodine test, which is better than the blood test 23:51 to kind of give an idea about it. 23:53 But there is no perfect test. 23:54 So this is where I'm right in the middle. 23:56 I feel that, yes, you know, we need iodine in our diet. 23:59 So that is again, depending on a person's diet 24:01 and lifestyle, certain people who are living in the coastal areas, 24:05 you know, eating seafood, seaweeds or sea vegetables on the daily basis. 24:09 Well, they are getting too much iodine, so they don't need 24:12 to kind of add any other iodine from in their diet. 24:16 But on the other hand, there are people who are not eating any of the iodine 24:20 rich food, no CV, no sea vegetables, or like no seafood or things. 24:25 Then definitely they need iodine in their diet. 24:28 Whether it can be, you know, through supplementation, 24:30 whether it is to iodized sea salt or whether it is to kind of, 24:34 you know, eating these CV or vegetables and things. 24:36 Now this is where salt 24:37 also comes into picture, because obviously now we have this wide varieties of salt. 24:42 You know, we have the regular table salt. Then we have the sea salt. 24:45 We have the pink Himalayan salt. 24:46 Then we have Celtic salt. 24:48 So like you know, people are like confused. 24:50 What is best for my thyroid which salt is good. 24:53 So again it depends on your iodine status. 24:57 The difference between these salts is the mineral content. 25:01 The salt is your table salt because it is stripped off of all the minerals. 25:06 Literally it only has sodium and chloride and you know, like added iodine. 25:10 That's it. Okay. Yeah. 25:12 While the other salt, like Celtic salt or pink Himalayan 25:14 salt has much more minerals in them, but unfortunately they are low in iodine. 25:19 So if you're that person who do not have any iodine in your diet, 25:22 then maybe sticking with iodized salt is a good choice for you. 25:25 But if you're that person you know 25:27 who have either iodine supplementation or iodine in your diet, 25:30 then definitely going going with Celtic salt or 25:33 ripping Kamali and salt, which has more minerals, will be better for you. 25:37 So this is where the iodine controversial thing, 25:40 you know, has a answer from my son. 25:42 Yeah. No. 25:43 That's great, I think. 25:44 Yeah, I think I'd rather see people supplement with a tiny bit of iodine 25:48 versus using table salt because it's, you know, it's it's a pretty it's 25:51 kind of like the junk food of the salt world kind of thing. 25:55 That's exactly what I do. 25:56 Also, I like recommend people 25:58 having some supplementation of iodine because again, it is more controlled. 26:02 We are knowing how much iodine is going in your person's body rather than just 26:06 kind of guessing in a food. 26:07 So yes, you know, like that would be my recommendation to also for people. 26:11 Okay. 26:11 So we're going to get to the our key star topic in a minute. 26:15 But before we go there, there's a lot of confusion. 26:18 People have a lot of confusion about what's a normal range 26:21 versus an optimal range of, of levels. 26:25 When we're talking about thyroid. 26:26 And this is when it comes to for T3, 26:30 I mean, I think we're all going to have a little bit of time in the system. 26:33 But where do you see those ranges? 26:36 Where do you like to see the basic ranges when you're looking at lab work, 26:40 so that people listening to this can go back to their labs and say, 26:44 oh, that's interesting. My doctor said this was normal. 26:46 Doctor Coupe De is telling me no, not so much. 26:49 Absolutely. So again TS right. 26:51 You know, if you look at the numbers, 26:53 the again, it's a very wide range that we are looking at now typically 26:57 you know goes from one to like, you know 4 or 5 as a normal TS. 27:02 What we believe is that for a person, 27:04 you know, like suggesting that they might be developing a tighter disorder, 27:07 then once your TS is going, you know, on the upper normal of twos or threes, 27:13 then that is definitely telling us that something is going on with your thyroid. 27:16 And there is a good point of time to look at your 27:19 thyroid antibodies as well as T3, T4 to kind of see what's going on. 27:22 Now once you're already on medications and things, 27:26 then typically I would like to keep that around two as much as possible 27:30 because again, that is the optimal range where your thyroid is working 27:34 in the best case scenario. 27:35 Now some practitioners feel that the lower the TS, the better it is. 27:40 So they will actually increase the dose of medicine so much that 27:43 the itch is less than one or like undetectable. 27:47 Yeah, I feel that's not the right thing to do, 27:49 because then we are putting those people into the hyper side of things. 27:53 They might feel good 27:54 because, you know, you have pumped up so much 27:56 tighter hormone, which is literally steroid. 27:58 So you'd have a lot of energy. 27:59 You can accomplish things, but on the long term basis, 28:01 that might not be the best choice for your heart, for your bones and other things. 28:06 So you're kind of sticking around. 28:08 The twos range is the best for the says that I would recommend. 28:12 And it goes again with reverse T3. 28:14 As are talking about reverse T3. 28:15 Again, everybody will have some of it. 28:17 So zero is never an answer. 28:19 You know? Again, there is no ranges for it. 28:21 But I believe that any reverse T3, which is more than 15 28:26 then I think that is significant. 28:27 That needs to be looked into. 28:29 What is causing the reverse T3 to get elevated. 28:32 So try to keep it less than 15 as much as possible. 28:35 Now in terms of three T3 and three D4. 28:37 Again, the ranges are very variable from lab to lab. 28:40 But what I will say is that don't try to be in the lower end of those ranges. 28:45 Try to be in the middle of those ranges of of your free T3 and free T4. 28:50 And I think again, your body and your thyroid is going to like that. 28:54 Yeah. Perfect. 28:55 Okay. 28:55 So we've talked a lot about diet and supplementation. 28:59 Well actually you know what 28:59 the one one thing we didn't talk about was selenium. 29:02 I mean, I like a religion. 29:03 I eat to Brazil nuts a day. I think they're delicious. 29:06 I've been told, and I believe that it provides my body 29:09 with enough baseline selenium that my bases are covered. 29:13 What are your thoughts on selenium? Because that's another one. 29:15 It's a trace element. 29:17 It's kind of people don't really think selenium. 29:20 Absolutely. 29:21 Again, selenium should be the like, 29:23 you know, should get the limelight which it deserves, which it doesn't. 29:26 Nobody knows about it. 29:28 And you know, it is a star mineral for your thyroid. 29:31 And most people are lacking selenium 29:32 because it is not present in a lot of foods. 29:35 You know, as you said, 29:36 Razzie nuts, you know, is the is the best source of selenium. 29:39 But how many people are eating Brazil nuts, right? 29:41 Unless a person is told to be, nobody eats them, right? 29:43 That's not the favorite people. 29:45 So that's the reason we do not get enough selenium. 29:47 And selenium plays very critical role in hormone production, 29:52 as well as plays a very critical role in conversion of your T4 to T3, 29:56 because selenium 29:57 takes part into certain enzymes, which are part of these differences, 30:01 and the super oxide mutations enzyme which are present in your thyroid gland 30:05 and leads to production of thyroid hormone and conversion hormone. 30:09 And again, 30:10 we have at least like 100 different research papers, which clearly shows 30:14 that people who are deficient in selenium, they have higher chances of 30:18 Hashimoto's disease. 30:19 And as soon as you replace the selenium, actually, the good news is that 30:23 the thyroid antibodies also start reducing and they start getting better. 30:27 So that's the reason selenium is 30:28 is very important mineral that anybody who has Hashimoto's or thyroid disorder, 30:32 whether it's graves also even in graves you can actually eat selenium. 30:36 And that will be useful to lowering those antibodies. 30:39 And as you said, the biggest or the best source of selenium, 30:41 if you want to get it through food is Brazil nuts. 30:44 Typically you like two Brazil nuts, you know, are enough of 30:48 to get the selenium in your body. 30:50 But again, the quality and the quantity 30:52 and where they are coming from, the selenium levels can vary. 30:56 But like on the general basis, 30:58 if you don't want to take any 30:59 supplementation, then I think taking Brazil nuts is a good choice. 31:02 If you know 31:03 like you are taking supplementation, then again, don't overboard onto it 31:08 because there is something called selenium toxicity because people think, 31:12 oh well, you know, like you know something is good, more is even better. 31:15 So let me kind of eat like four or 4 or 5 Brazilians. 31:19 Plus, let me get this side or supplement, you know, which has selenium into it. 31:22 Well, you know, you're overdoing it 31:24 because you only need 100 to 200 micrograms of selenium. 31:28 Anything more than that over the course of long term basis 31:31 can cause toxicity to the people. 31:33 So again, just kind of looking at your complete picture of your diet 31:37 as well as supplementation and sticking to that. 31:39 But yes, selenium is very very important for your thyroid gland. 31:42 Yeah, I don't know. 31:44 There was a show or a movie once and it was seared in my mind 31:48 where the guy ate Brazil nuts like all day or something and got. 31:52 So it was almost, it almost mimicked, I think, almost like radioactive exposure 31:58 or something like it was a very like it. 32:01 This is very much a sweet spot supplement, folks. 32:04 So don't definitely, as Doctor Gupta says, enough is enough. 32:09 More is not better. 32:10 Knowing that there is less and more. More will make you sick. 32:13 So okay, so we're getting to the heart of the issue here. 32:18 And so when do you decide when diet and supplementation right is just not enough. 32:24 And when does a case need more advanced interventions. 32:27 This is where we're aiming. How do we decide this.
Iodine, Selenium, and Optimal Thyroid Ranges 32:30 So I think I mean, what I've realized over the course of these years is that, 32:34 you know, waiting for a long time to introduce certain advanced 32:38 things like peptides or bio regulators. 32:40 We don't have to wait for them because this 32:42 Hashimoto's disease is not an easy disease, is a pretty complex disease. 32:46 So we have to card from all different angles. 32:50 So for me, it's like when people are starting with me. Yes. 32:52 You know, 32:53 like anybody who's sitting at home, they should start with a diet 32:56 and basic supplementation. 32:57 But when you're working with a provider like, you know, people, when they start 33:00 working with us, we start building their protocols 33:03 by involving bio regulators, peptides, supplementation and diets. 33:08 So we are hitting hard the body from all different angles. 33:12 When I say hit 33:12 hitting hard doesn't mean that you are going to feel worse, actually. 33:16 Basically just, you know, incorporating each and every way 33:20 of supporting your body in all different ways or fashion, 33:24 because every vitamin, every mineral or every peptide you're going to introduce 33:28 has a different mechanism of action, and they're going to help your body 33:32 in all different ways, and that is what is needed. 33:34 We need all hands on board. 33:36 So for a person to get better. 33:38 So for me I don't wait very long time. 33:41 You know I will just start them, you know initially itself. 33:43 But yes, you know, as we discussed before, also when you are introducing 33:47 bio regulators and peptides, you need to work with a practitioner 33:50 who is well versed with those so that you don't harm your body. 33:53 Instead, actually, there will be useful for you. 33:56 Yeah. Fantastic. 33:57 So I'm you know, when you look at peptides, are you looking 34:01 at them as symptom tools, root cause tools or maybe recovery accelerators 34:07 layered on to the work that you're doing, or maybe all of the above? 34:12 I will say all of the above. 34:13 Yeah, yeah, yeah, no for sure. 34:15 The good part is that we have so many different peptides. 34:18 And the worst part is that unfortunately, 34:21 Hashimoto's people have so many different symptoms 34:23 and so much going on in the in terms of root causes. 34:26 So again, different people will need different help. 34:29 Some people just need symptom relief. 34:30 So obviously we use certain peptides for that. 34:32 But a lot of people almost everybody will need that root cause relief. 34:37 So definitely peptides 34:38 you know to work on those root causes are a very cornerstone over here. 34:42 Yeah. So we're going to talk about that now. 34:44 So we have our first contestant BPC 157. 34:48 Let's talk about the role that it's playing for you with your thyroid patients 34:52 I think you know 34:53 we talked earlier about the gut, but we also talk about oh immunity. 34:57 Do you want to talk a little bit about where 34:59 BPC kind of fits fits in there for your patients. 35:03 So BPC is kind of one of those base peptides 35:06 is what I call it that, you know, almost everybody can benefit from it. 35:09 And the good part is that, you know, it doesn't have much downside. 35:12 It doesn't have too many side effects very well tolerated from people. 35:16 So again, 35:16 as we know, BPC is basically a peptide, you know, which is generated in our gut. 35:20 And you know, we have seen that it has plays multiple roles. 35:23 You know, it helps, you know, in healing your gut, specifically people 35:27 who have intestinal permeability or leaky gut issues. 35:30 BPC, you know, can be helpful for healing that. 35:33 And then plus obviously in general healing your body, whether it is 35:36 your ligaments, your muscles and other things. 35:39 BBC plays a significant role. 35:40 So in order Hashimoto's patients, definitely the thing that starts 35:45 the whole process of leaky gut and gut permeability, you know, BPC 35:49 directly addresses that and works, you know, on healing the gut. 35:52 So that is one kind of base benefit from it. 35:55 A lot of tired patients will have chronic pain issues. 35:57 They have too much inflammation going on in their system. 36:00 And again, by having the healing power 36:03 of regenerating, you know, the ligament and muscles, it can reduce the pain. 36:07 And plus, you know, it also works on some of the inflammation 36:11 pathways and reduces inflammation in your body in general. 36:15 So that's an easy peasy, 36:17 you know, works in multiple ways of helping the Hashimoto's clients. 36:20 And that is one of those ways peptide that, you know, I can like 36:24 start adding from day one so we can start getting their gut and other other things. 36:29 Yeah. Fantastic. Okay. 36:31 I have another question I'm going to ask you. 36:33 I want to move through the 36:34 because you have four peptides that you really focus on in your practice. 36:37 The next one that you talk about a lot and makes sense 36:39 given our conversation leading up to here is thymus and Alpha one. 36:42 And I you know, my understanding is you really use it 36:46 particularly with people 36:47 who might be dealing with an Epstein-Barr virus reactivation, obviously 36:52 immune dysregulation or even if they have some current infections going on. 36:55 Do you want to talk a little bit about to one and how it plays a role here? 37:00 So time was an alpha one peptide as we all know is basically working 37:04 with your thymus gland. 37:05 Now thymus gland is the one which helps us in 37:08 making our whole immune system when we are young. 37:12 You know, with this time, gland trains our immune system 37:15 so that it can fight off with potential infections as we age. 37:19 Now what happens again is that as we age, sometimes, you know, 37:22 our body's immune system, you know, sometimes goes into the other direction. 37:25 So thymus and alpha one can retrain the immune system 37:29 so that it fights the external infections and not your own body. 37:33 So that's the reason in Hashimoto's it is very important over there. 37:36 And research studies, you know, which supports the thymus. 37:38 Alpha one has been useful in several chronic infections. 37:41 Whether it is hepatitis viruses you know, it has been used. 37:44 It has been used in other infections too. 37:46 So that's the reason 37:47 I love thymus one specifically, if I'm suspecting any kind of infections, 37:51 whether it's Epstein-Barr virus, whether it's Covid virus or even kind of, 37:55 you know, any parasites or immune dysregulation where people just 37:58 immunity is just weak in general, they will get common cold. 38:01 Very often they will get other infections very often. 38:04 Time in alphabet is very great. 38:06 Plus what it does is that it retains your immune system in reducing inflammation 38:10 so that we can see beautifully that inflammation in the thyroid gland reduces. 38:14 And those antibodies also start coming down. 38:17 So very important peptide 38:19 that you know is plays a very crucial role in Hashimoto's patients. 38:23 Fabulous. 38:23 Now there's another thymus peptide that you use as well. 38:26 I was interested to see this when I was reading up on you. 38:28 And that's thymus in beta for when do you use when do you bring that. 38:32 Because I think it plugs a couple of other holes. 38:34 It's also, you know, kind of BPC 157 BF but thymus in beta for you. 38:39 You seem to layer that into your protocols as well with patients. 38:44 That is correct. 38:45 So again 38:45 you know like we start off with BPC thymus and Alpha one in certain people. 38:48 And then later on sometimes you bring in TB for the reason 38:52 being TB for again, you know, like takes the healing process to the next level. 38:56 So people who already had damage to their kind of nervous system, 39:01 you know, had like traumatic brain injuries or people, you know, 39:04 have had injuries to their spine or ligament or other things. 39:07 Thymus beta for is very great. 39:09 And again, a lot of tired patients will have inflammation in their system. 39:13 They will have chronic pain or they might have nervous system 39:16 dysregulation in terms of brain issues like brain fog and things. 39:20 I think for again, first of all, not only improves in reducing inflammation 39:24 in this system, but also takes that healing of the body, 39:27 which is very important because the body has taken 39:29 a lot of beating from those antibodies for a long time. 39:32 So thymus and beta four helps in healing the body from all the damage 39:37 it has been gone through, and again helps people in improving 39:40 their inflammation levels as well as healing process also. 39:44 Yeah fabulous. 39:45 Okay, last one and this is a tricky one because this is this 39:49 I consider this peptide to be a little bit like our conversation
When to Use Peptides in Hashimoto's Care 39:52 on selenium and iodine where there's a sweet spot for it. 39:55 And if you go too far over especially too much of it, 39:59 it can really backfire on people. 40:01 So and this is HL3 seven. 40:04 This is the small molecule. 40:05 This is the peptide that really it's almost like the antibiotic 40:09 of the peptide world. 40:10 You know it's it's the heavy hitter when we're talking about mold parasites 40:15 and even Lyme. 40:16 But you know what's the clinical upside you've seen clinically. 40:20 And then where do you know that you have to really tread carefully with this one. 40:25 So lucky seven is not the peptide that I use in each and every client of mine. 40:29 Because as you said, you know, yes, it's only certain indications will use. 40:32 So people, you know, again who are very heavily infested with mold, 40:37 you know, that's one thing. Use it. 40:38 The second one is that, again, people have a lot of chronic infections. 40:41 You know, like we do the testing there Epstein-Barr versus positive there. 40:44 Covid is positive. 40:44 They are positive for Lyme but BC or Bartonella. 40:47 Now obviously to make a plan for them to address all of these infections becomes 40:51 very, very big challenging because those people have taken 40:54 IV antibiotics for a couple of years, you know, because the lime doctors love it 40:58 and doing these things. 40:59 But again, that completely shorts out 41:01 the gut immune system and the gut microbiome and things. 41:03 So this is where L 37 is very useful that, 41:07 you know, it has shown a lot of antimicrobial properties, 41:10 you know, against viruses, against bacterias, against even Candida. 41:14 And similarly with mold. 41:15 Also, you know, it is very useful at 37 because again, it up 41:19 regulates your immune system. 41:21 Now with little 37. 41:23 Yes, we have seen some people which are very sensitive. 41:26 It can hyper regulate a person's immune system also specifically 41:30 if you're using it very very high doses. 41:32 So again we try to use the smallest dose and you know go very slow with that 41:36 and see the responsible person. 41:37 And then increasing it and again using it for a short duration of time, 41:41 maybe for like 3 to 4 weeks or so, and then kind of giving their body a break 41:45 and seeing how that works. 41:46 And then maybe if you need 41:48 another round of it, then we use it later on, but only, as I said, 41:51 for people who have chronic infections, multiple of those or they are having 41:56 very heavily infested with mold 41:58 are the only two patients that will typically use L3 seven. 42:02 Otherwise, you know, like we don't use it, you know, we stick better 42:05 or we do the other peptides more often than this one. 42:08 Yeah. Yeah. 42:09 It's it's a strategic tool I think. All right. 42:12 So as we close up on the peptide section, what what are the mistakes that you see 42:17 from patients or practitioners using peptides 42:20 without really understanding what they're dealing with here. 42:23 Like really understanding the auto immune context. 42:26 Like or maybe it's the terrain like where do you see people going astray? 42:30 And I think also mostly probably with patients who are now 42:35 they have so much information at their fingertips, they're like, 42:38 okay, I can do this, I'm going to do this on my own, which is great. 42:41 But where do you see the pitfalls on that? 42:44 So first of all, as we discussed before, also it is about the 42:48 quality of the peptides. 42:49 You know, like you know, because you know, like 42:51 these are so easily available, 42:52 people can go on internet and start buying these peptides. 42:55 But again, you know, like because they're not regulated. 42:58 So that means you do not know what you're injecting in your body. 43:01 Right. 43:01 Because these are lab made and there is no certifications with them. 43:04 So these updates often are first of all useless because they do not, 43:08 you know, qualify as, you know, a particular supplementation. 43:11 Second of all, sometimes they can be having viruses of their own. 43:15 They can be not produced properly. 43:16 So they can be actually having different germs. 43:19 So don't buy off internet without doing the research of a certain company. 43:23 And same with practitioners is that don't kind of use companies 43:27 which you do not do not follow the good quality standards. 43:30 My standards are that okay. 43:31 Well that particular company who is making that peptide 43:34 or a bio regulator should be located in United States. 43:36 So at least they're following certain norms. 43:39 And then, you know, 43:40 because a lot of peptides car coming from outside the country 43:42 and we just don't know how they're being produced. 43:44 So first of all quality quality very important over there. 43:48 The second of all is that, 43:49 you know, again there is stacking is very popular in peptide world. 43:53 You know, people will say, okay, well, you know, 43:55 why don't you combine this, this, this, you know, like 4 or 5 peptides together. 43:59 Well, no, you know, like you, 44:00 unless you are sure what you're exactly doing, stacking is not the best option. 44:05 Yes. Couple of peptides. 44:06 Like sometimes you combine BPC with CFPB.
BPC-157, Thymosin Peptides, and L-37 44:09 Okay. That makes sense because they're both working in the gut. 44:11 They are working on different mechanisms. 44:13 So that is fine to do. 44:14 But sometimes people are using CFPB and BPC and then TB 500 and TB alpha one. 44:20 And then you know add you know like an alpha one or sometimes other things. 44:24 I think that's too much. 44:25 So again 44:26 same with practitioners as well as the patients is that start 44:29 with 1 or 2 peptides so that which are one of the safest ones 44:32 and then slowly build it up if you want to. 44:35 I my rule is that, you know, I don't stack like 4 or 5 peptides. 44:39 It's like, you know, couple of reptiles at the time 44:40 and then use them in a sequential manner because they're doing 44:44 certain things in your body. 44:46 And the the interesting thing about peptides 44:48 is that, yes, we can define their major function, 44:52 but what we realize is that one peptide is just not doing that major function. 44:57 There are 100 other minor functions in your body. 45:00 It is affecting to. 45:01 And you know, there is no way 45:03 for us to know the complete extent of what these websites are doing in our body. 45:07 So that's the reason again, kind of, you know, 45:08 not stacking them is very important. 45:11 The third thing is that again, sticking with the required doses 45:14 again, more is not good in this situation. 45:16 Oh well, you know, 500 you know BPC is great. 45:19 Let me just kind of take 2000, you know, a day and see how that works. 45:22 Well, no, 45:23 you know, again you know, making sure that you are taking the right dosages in 45:27 the right way is very, very important so that you are not overdoing on them. 45:31 So I think these are the common mistakes in common 45:34 kind of cautions that I will tell people working with the right provider 45:37 who knows exactly what he is doing specifically, if you are using it 45:41 for particular disease 45:42 like Hashimoto's or any other autoimmune or any other diseases, 45:45 if you're just doing it for general health, then yes, you. 45:48 There are certain set of safer peptides. 45:50 You can do it, 45:51 but when you're doing for a disease, you need to know what you're doing. 45:54 Yeah. 45:55 And I would say with the immune peptides it's particularly tricky. 45:58 Like you need to understand what your immune system is doing, how 46:01 the moon peptide works so that you don't risk exacerbating a problem. 46:07 You know, we we automatically assume, oh, 46:09 thymus and Alpha one's going to make everything better. 46:10 But sometimes it can really ramp up the innate immune system. 46:14 And that's not exactly what you need right now. 46:16 So I think it's you know, these are 46:18 these are the finer points that these are the clinical pearls that as a physician, 46:23 you've collected over the years clinically and through the research, 46:26 that really helps you to know how and when to use the peptides properly. 46:30 So moving over to the bio regulators, because we're going to come up on time 46:34 very soon, I'm not very good at staying under an hour, doctor. 46:37 I'm sorry. 46:38 So very quickly, like how do you distinguish peptide 46:41 therapy from bio regulators both conceptually and clinically. 46:44 Like how do you see fitting differently into this picture. 46:48 So you know, like basically kind of knowing people about 46:50 what is a bio regulator and what is a peptide. 46:52 So peptides you know, are again collection of amino acids, shorter 46:55 collection of amino acid than proteins, which is around 20 to 30 amino acids. 46:59 Bio regulators are even shorter collection of amino acids, 47:03 maybe five, three or even like less than ten or something. 47:06 So that's the difference. 47:08 So bio regulators are more precise way of working 47:11 on a particular kind of, you know, organ or a particular disease. 47:15 So that way, you know, like we are using it in a more precise manner. 47:18 So that's a good part about bio regulators. 47:20 Well, peptides, you know, as we say that, you know, we have more research on them. 47:23 But you know like they are longer changed. 47:25 So they are working on multiple pathways. 47:27 The good part is that, you know, sometimes I bring bio regulators 47:30 because now we have thyroid bio regulator which is very specific for gland. 47:35 So as I deal more with Hashimoto's and thyroid patients 47:37 now I can be more specific, you know, and there is good amount of things 47:41 I've seen that improves antibodies and supports a tired functioning. 47:45 Similarly. 47:46 You know, we have, you know, 47:47 bio regulators, which supports the kidney function, 47:49 which a lot of times we use because people will have high amount of toxins 47:53 so that we can work on the kidneys that way. 47:55 Sometimes we have bio regulators, which works on the pituitary gland and things. 47:59 Again, that can be useful specifically if multiple hormones are affected 48:03 in that particular person. 48:04 So we can see that pan hypo pituitary is happening or there is a chance of that. 48:09 So again supporting the pituitary gland to work on those or pineal gland 48:13 in that way. Also working on it. 48:15 So that's why I like about these bio regulators is that, 48:17 you know, I can use them, you know, very precisely for, 48:20 you know, for a particular patient or a client, you know, when I see 48:24 there is a need to support that specific organ over there. 48:28 So that's the way I differentiate with that. 48:30 Almost all of my patients will use a thyroid bio regulator because obviously 48:34 like, you know, as they have Hashimoto's and they have hypothyroidism. 48:37 First of all, we see good improvement in their thyroid antibodies. 48:40 So that is good 48:41 because it reduces inflammation, supports the thyroid gland functioning. 48:44 Second of all, 48:45 a lot of those patients we see their thyroid hormone levels also improving.
Peptide Pitfalls and Bio Regulators for Thyroid Support 48:50 Their improved at E3, T4 hormone levels improve. 48:53 And the medicine that they were using is working better for their body. 48:57 So that's the reason the thyroid bio regulator 49:00 is one of the most favorite ones that you know, in the recent I will say 49:03 one year is I'm using more and more in my clients. 49:06 Yeah. Quick question. 49:07 How have how have peptides and bio regulators changed your practice 49:12 because you didn't you know, you've been in practice a long time. 49:15 They weren't always as available as they are now. 49:17 What would you say 49:18 has been the biggest impact of these small molecules on your clinical practice? 49:23 I will say that, you know, before I had tools, you know, tools of diet, of 49:27 life style tools or certain supplements, and we see great results with those. 49:31 And adding these peptides and bio regulators, we are seeing better results. 49:36 You know, I will not say that, okay. 49:37 Ties in the bio regulators have completely transformed 49:39 Hashimoto's clients and we don't have to do anything else. 49:42 They alone can do it. 49:44 Not really. But this is one more tool. 49:47 When I add to my people again we see much more better results, 49:51 much more better results there through antibodies, 49:53 which will take sometimes one year to come down. 49:56 Now we can shorten them out. 49:58 And even in 4 to 6 months now we are able to reduce the antibodies 50:01 and sometimes even back to normal in 4 to 6 months when we use the peptides 50:05 in bio regulators. 50:06 So that means the healing process is accelerated. 50:10 So first of all, we better improvements in numbers easily. 50:14 And second of all, symptom wise also that people see much better improvement 50:18 in their fatigue, their energy, their brain fog, even moving their weight 50:22 around. 50:22 You're seeing much quicker results as compared to before. 50:25 So I think that has been the biggest change that I've seen in my in my clients. 50:31 Fantastic. All right. 50:32 A few little rapid fire short little questions. 50:34 Short little answers. 50:35 Before we go, what is one thyroid lab 50:38 marker that deserves more attention, in your opinion? 50:41 Reverse. 50:42 Most overlooked reverse T3, one root trigger that is still underappreciated. 50:49 I'll say toxins. 50:50 More toxins specifically. 50:52 Yeah. 50:52 What's the one peptide 50:54 that surprised you the most clinically when you started using it? 50:58 I would say the combination of BPC and CFPB. 51:00 I was not using CFPB before, 51:02 so that combination actually works really much better. 51:06 Beautiful. 51:06 One mistake patients make when trying to heal Hashimoto's 51:09 on their own going on extreme diets. 51:13 People are going on very, very extreme diets, low calorie diet just to lose 51:16 weight or limiting or eliminating almost every categories of food. 51:21 And that extreme 51:22 diets, you know, backfires most of the time in the long term basis. 51:26 Now, what is one area of thyroid medicine that you think 51:29 will look very different in five years? 51:33 Well, I don't think not much is going to change. 51:37 I hope it does. 51:38 But I still feel the endocrinologist societies are not still looking much. 51:43 But one change actually, I feel, 51:45 is that at least they are recognizing the role of T3 medicine. 51:48 So more and more 51:49 endocrinologists are now prescribing or adding T3 medicine along with T4. 51:53 So I think that is a good addition, 51:55 and I think that is going to be more mainstream practice as we go along. 51:58 And then in the next five years, I just hope, you know, 52:01 like I don't think that has happened, but I hope that they start looking 52:04 at the immune dysregulation of Hashimoto's and try to find answers for it. 52:08 So that's my hope that, you know, they will start looking into that 52:11 beautiful doctor Gupta, this has been fantastic conversation. 52:15 As always. 52:16 Thank you so much for your generous generosity of time and information. 52:21 Please let people know where they can find you and where they can find your book. 52:25 Absolutely no. 52:26 First of all, thank you so much for having me over here. 52:28 You know, it's a great pleasure. 52:29 What work you're doing is amazing. 52:31 So I really appreciate everything, you know, 52:33 that you are sharing and doing for people. 52:35 So thank you so much. 52:36 In terms of people where they can find me. 52:38 So, you know, I share information in all different ways. 52:41 If you are a person who want to watch, 52:42 then I have a YouTube channel which is called Gupta, M.D.. 52:46 We put out regular videos about what you can do today to improve things. 52:50 Then I have a very active blog on my website. 52:53 Again, the name is AnshulGuptamd.com 52:56 which again research based information is what I shared over there. 53:00 And a book is reversing Hashimoto's. 53:02 That's the name. 53:03 And you can find it on Amazon or any other 53:05 like online book outlet that you want to buy it. 53:07 You can buy it from there. 53:09 Beautiful. Thank you so much. 53:11 Have a beautiful day. 53:12 Thanks everybody for joining us. 53:13 And we're off to the races. Thank you.
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