Full Transcript Introduction to Dr. Holtorf and Bioregulators 0:00 Welcome back to the Bioregulator and Peptide Summit. 0:02 Ladies and gentlemen, we have a great guest here with us today. 0:06 Truth is, if you've spent any time 0:08 in the world of integrative or functional medicine, chances are 0:11 you've come across the work of today's guest doctor Kent Holtorf 0:15 is a physician, researcher and the founder of the Holtorf Medical Group 0:20 in Network of Clinics at the forefront of evidence based, 0:22 cutting edge medicine specializing in thyroid disorders, 0:26 hormonal optimization, chronic fatigue, Lyme disease and longevity medicine. 0:30 Doctor Holtorf has built a reputation for going deep into the science, 0:35 not just adopting emerging therapies because they're exciting, but rigorously 0:40 interrogating the mechanisms and clinical data behind them. 0:44 He's a published author, a frequent speaker 0:46 at leading medical conferences, and a physician who has treated 0:49 thousands of complex, hard to crack patients, often 0:52 after conventional medicine has fallen short. 0:55 What I love about having Doctor Holtorf for today is that he brings both 0:58 a clinical lens and a scientific one, and that's exactly the kind of perspective 1:03 that we need in this space when we're talking about one of the most fascinating 1:07 and still underappreciated areas in longevity medicine bioregulators, 1:11 these short chain peptides, many of them developed from decades of research 1:15 out of the Saint Petersburg Institute of Bio Regulation in gerontology, 1:18 are beginning to capture serious attention for their ability to restore tissue 1:22 specific gene expression, slow biological aging, and support organ 1:26 function in ways we've barely scratched the surface of Doctor Holtorf. 1:30 Welcome to the bio Regulator and Peptide Summit. 1:32 I am so thrilled that you are here today. 1:35 Oh my gosh, you are so kind. 1:37 I need to hire you as a PR. Thank you. 1:40 Absolutely. 1:41 Well that's true. 1:43 Well, no, you deserve all of that. 1:45 It's a little bit. 1:46 You've been you've you've been in it for a long time 1:49 and fighting the good fight. 1:50 And I've always said this to me is especially in this day of social media, 1:55 where people will plant a flag on a hill and they will die on that hill. 2:00 And it doesn't matter what comes up, what they learn, what's new. 2:04 They've taken a stand and that's just where they're going to sit. 2:07 And what I love about you and to me, the hallmark of a great 2:12 physician is someone who's a who's able to acknowledge 2:15 that we don't have all the answers and who's willing to change and evolve. 2:20 As the as more information unfolds and that's what it has to be all about, right? 2:25 Because we just don't have all the answers. 2:27 I don't know that we ever will. 2:29 And I agree with that. 2:30 And now it's like, you know, I 20 years ago 2:34 there used to be medical debates. 2:35 Now all of a sudden, like you try to have a medical debate like, 2:38 look, my, my point of view, here's yours and it comes. 2:42 It breaks down to like, your racist, you know, or it's crazy. 2:46 And like, la la la la. I don't care about the studies. 2:49 This is what I believe, you know. 2:51 Yeah, and I missed that. 2:53 Yeah. 2:54 No, I mean, we I think the wheels kind of came off that bus back in 2:58 when Covid happened, right? 2:59 It just the world became both hyper polarized and allergic 3:05 to a healthy discourse, which, frankly, is the foundation of medicine. 3:10 It's the foundation of science. 3:11 It's the foundation of our society that. We live in. 3:14 Science has been hijacked. 3:15 It's horrible, and I apologize. 3:17 I'm talking very strange. 3:19 I had oral surgery, so I'm kind of a filly. 3:22 Thessaly Whitley, doctor. We're all good. 3:24 We understand where I'm grateful you're here because we couldn't. We? 3:28 I kind of stuck you on the time. So we. 3:31 It is what it is. You're still speaking very clearly. 3:33 We're we're good with that. 3:34 And and further to that, there are some one thing I, you know 3:38 there's a before we get into what we're going to talk about today, 3:42 we know that there's some real naysayers out in the industry 3:46 really putting down the bio regulators.
Personal Journey into Peptides and Bioregulators 3:48 And it's almost like now we've got two camps. 3:51 We've got the camp that says bio regulators 3:53 are an emerging tool that we really need to pay attention to. 3:58 And frankly, in the. 3:59 Same camp. That's our that's our camp. 4:02 And truthfully, emerging is generous because they've been studied for over 4:06 three decades in Russia and they're still being studied, and not just Russia. 4:10 I mean, Russia, that whole part of the world. Right? 4:12 Not to mention that there's universities in the US that are doing studies. 4:16 There's universities in Italy doing studies 4:18 like there's it's there internationally of interest. 4:22 And frankly, if they were so useless, 4:25 why would the FDA bother putting one of them on its no go list? 4:30 I'm just saying. 4:32 Right. 4:33 So if it doesn't work, why be scared of it? 4:36 Right. Exactly, exactly. 4:38 So, you know, before we jump, we've got a list of questions for you here. 4:42 But I think before we jump 4:43 in, why don't you tell us a little bit about your history with bio regulators? 4:47 Like when did you first hear about them? What caught your attention? 4:50 What have you seen in your practice that's made you kind of sit 4:53 and stop and go, wow, we need to pay attention to this stuff. 4:57 Yeah. 4:57 I mean, so my whole introduction to peptides 5:00 was I've been chronically ill, you know, chronic Lyme. 5:04 I got in vitro, chronic Lyme, BBC, 5:08 Bartonella and was doing okay all through my life. 5:12 And but all of a sudden in medical school just just totally tanked. 5:16 I couldn't think just anxiety 5:21 or pain all over 5:22 my, you know, skin couldn't sleep. 5:25 And I would go to, you know, basically doctors or doctor university doctors like, 5:30 oh, I don't know what's going on. We can't help you. 5:32 And and basically I said, look, I'm going to 5:36 off my shelf or I'm going to cure myself. 5:38 So I went around the world looking for treatments. 5:41 Never heard of peptides in my life. 5:43 We went to Mexico and got a bunch of plasma freezes and basically natural 5:48 killer cells and dirty cell therapy ended up in Europe and it was in Belgium. 5:53 And I got some peptides just wearing them. 5:56 Like two days later, I couldn't, I couldn't not a chronic heart failure 6:01 because of heart failure. I could not stand up. 6:03 I could not walk upstairs. 6:05 So I'm like traveling through Europe, bent over, walking one mile an hour. 6:10 And B cardiologist said, maybe in ten years you can get 10% better. 6:14 And and so I'm just like, okay. 6:17 And then I went and went with Terry Hertog actually. 6:21 Yeah. And then he prescribed some peptides for me. 6:24 And then two days later I just walked up the stairs. 6:27 I'm like, I'm standing upright like, what the hell? 6:30 I go can't be the peptide. 6:31 And then it kind of tailed off and I did it again. 6:34 My God, it transformed me. 6:37 So just really got into peptides. 6:39 And then and then from there, you know, from peptides and bio regulators. 6:44 And I think those bioreactors 6:47 are a subset of peptides, short shorter peptides. 6:50 But I mean it changed my life. 6:52 And I've seen in the last 20 years changing the lives of my patients. 6:57 And you know, myself, as I mentioned, and just been expanding it from there. 7:01 Yeah. 7:01 So you you mentioned the so when Doctor Hertog prescribed the peptides, 7:07 were they the, the signaling peptides or were they by a regulators at the time. 7:11 Yeah. 7:11 At that time it was it was be injectable. 7:14 But the injectable bio regulators are injectable like like a T or invaded. 7:20 Alpha one. 7:21 Okay. V BPC. 7:23 But that got me introduced to the whole. 7:26 That whole area. 7:27 Yeah. The whole scene. 7:30 The scene baby. 7:31 The peptide scene. Yeah. 7:33 So what about the bio regulators scene? 7:35 What got you there? 7:36 Yeah. 7:37 I mean, I think just, you know, being enthusiastic about it 7:41 just started looking like, hey, what about these? 7:42 You know, looking at these studies on with Cabazon and Pavlov, you know, 7:49 you know, reversing the basically deterioration 7:52 of their military personnel and just it's fascinating. 7:57 And they fricking work. 7:59 And I've seen them work over and over and over. 8:02 I mean, patients that are so sick and they work. 8:06 Yeah. 8:07 So it's like you have to just keep expanding 8:10 because so many things are actually so helpful. 8:13 I've had a couple of doctors on this summit actually. 8:16 People may have I don't know what the order of operations is going to be 8:19 when we release these episodes, but talk about how the bio regulators 8:24 in particular, as well as peptides, they feel like it's cut 8:28 the time that it takes them to move the needle on complex patients in half. 8:32 Absolutely. 8:33 For instance, the kidney bio regulator, we I gave 8:37 one of our medical assistance there. 8:39 Her mom was on dialysis. 8:41 And I go, I take the kidney bio regulator. 8:43 And I forgot about it. 8:45 She forgot about her mom. 8:47 I talked to her and says the doctor said she's never seen anyone get off dialysis. 8:51 Yeah. You know, and. 8:54 The only thing, just the kidney. 8:55 No. No blood vessel, nothing else. 8:58 Just. Yeah. 8:59 Just gave her just the kidney. But you're right. 9:01 Like the blood vessel makes everything work better, right? 9:04 Yeah. 9:04 I'm not going to talk about his stacks, 9:06 because, you know, this one works, but this works better.
Safety, Mechanisms, and Oral Bioregulator Basics 9:09 Yeah. But yeah. 9:10 And I'm like, oh, my God, I totally forgot. 9:12 We gave it to her. And of course. How much did you get? 9:15 How much did you give her. 9:16 How long did she take it for. 9:17 She must. Take no, no, you know. 9:20 Gave her a. Bunch of it. And that. What. 9:23 You just gave her a bunch? 9:24 Yeah, exactly. 9:26 Whatever. 9:26 The technically defined as a bunch. 9:29 Yeah, like a shitload. That infamous dose. 9:32 Yes, the magic dose. 9:33 And I don't know what what she took, but I was like, 9:36 oh, crap, I forgot about that, you know? 9:37 But we have so much. 9:39 In fact, this may be a little TMI, but I have chronic kidney disease 9:44 from chronic Lyme, and I have so many autoimmune 9:47 diseases and I have actually show Grenz disease. 9:50 So I have no make no saliva, which by my teeth are all ept up. 9:53 But I tell people. 9:55 Oh, do you have foamy urine? Right. 9:57 It shows that you're dumping protein in the urine. 10:00 Take the kidney by a regulator. 10:03 And again, if you had the vessel and some other things 10:05 actually make it work better, and after like sometimes 6 hours 10:09 or 12 hours or a day, the foam goes away. 10:13 It's that. And so that's interesting. 10:15 You know, I would never I never believe that they worked that immediately. 10:19 But I guess that you're you're talking about this. 10:22 And I interviewed somebody else yesterday, Hunter Williams. 10:25 And he was talking about the synthetic injectable cartilage peptide 10:29 and talking about in his case he finds he feels that it 10:33 it acts almost immediately like within a day or two. 10:37 Yeah. No, I see it myself. 10:39 And then of course, he's eating herself. 10:41 And then you use it on people and they're like, yeah. 10:44 So now my friends are like, 10:45 I got from a year and give me whatever you. 10:47 Do, I need that bunch. 10:48 So speaking of the bunch, right. 10:51 I think that brings us brings up a really interesting point 10:54 that you would feel comfortable just handing a bunch of this product over 11:00 to, to this person who, you know, has a kidney issue, 11:04 but you're not really that concerned. 11:06 Is she going to take too much? Is she going to take too little? 11:08 Do you want to talk about the safety profile of the bio regulators 11:13 that you've seen clinically? 11:14 And that is that is documented in the research? 11:17 Yeah, I mean, because I am the most lazy patient there is. 11:21 So I will instead of trying to take two a day, I can't do that. 11:26 So I'll just take 21 time 11:29 and but yeah, there's there's no I've never, never seen a side effect. 11:33 I've never seen any even allergic even with the, 11:36 you know, Sears patients, the patients. 11:39 I've never seen a negative reaction. 11:43 Yeah. 11:44 I think part of it is that the mechanism of action, right where the, 11:49 you know, all of the research that Kevin Sun published really speaks 11:53 to this normalization of function rather than a boosting or a suppression, 11:58 and that really sets the bio regulators apart 12:01 from the signaling peptides and drugs. 12:04 It's not pushing. 12:05 I don't think you can overdose. 12:07 It's like and to your point is probably taking 20 12:12 probably not the best way to do it because yeah, because when you look 12:16 at the mechanism of action that it's better 12:19 to do a little bit over a long period of time than any big. 12:23 Yeah. Yeah, no for sure. 12:24 But the, you know. 12:26 Not as I do. 12:28 Yeah. 12:28 Well and I think that one of the things, one of the studies that really highlights 12:33 that is when Kevin did the old people studies 12:36 and then went on to talk about the effect of the pineal gland 12:40 regulator on sleep and melatonin production, 12:44 is that if you were to give that same pineal gland bio regulator 12:48 to a young person who's sleeping great, doesn't have any circadian issues, 12:52 they're going to be like, this stuff doesn't do anything right. 12:56 Whereas in an elderly patient, it's magic. 13:00 Which shows the safety of it, right? 13:01 It's not going to push you out of the abnormal realm. 13:05 Yeah, yeah. 13:06 Which is that I mean, to me that's just the it's 13:09 the magic of this stuff that it just it's just very. 13:14 Now, I have heard people talk about how in very hypersensitive patients, 13:19 they sometimes have to reduce dosage or, you know, modify their protocols 13:24 a little bit, 13:25 but almost always they're able to work people up eventually to that, that. 13:30 You know, those super sensitive patients like, 13:34 you know, 13:34 it's the whole look at the pill, you know, think about the pill for a week 13:37 and look at it and then smell it and then lick it and then yeah, 13:41 you know, I mean, they react to it's amazing what they can react to. 13:45 But it's anything it's like a new basically food or something. 13:50 But yeah, I mean that's a rare population. 13:53 But they know who they are right. Yeah. 13:55 And someone says I'm sensitive. 13:57 Doctors have to listen. They go, oh yeah, yeah, yeah. 14:00 And they give them the same dose. No no no no. 14:03 100%. 14:05 So let's talk a little bit about what we're going to be talking about today. 14:07 Today we're speaking specifically to the oral bio regulators. 14:11 And we're talking about the natural extracts here. 14:14 Right. 14:14 So this is so we have in the bio regulator realm 14:17 we have the synthetic bio regulator which is the isolated amino acid 14:22 chain that the Russians, the researchers determined 14:26 was the most active of the peptides and small molecules in that extract. 14:31 Whereas when you're taking that natural bio regulator in a capsule, 14:35 you're getting you're getting kind of like 14:38 it's almost like an organ extract, but it's more refined than that. 14:41 Does that make does does that. Yeah. 14:44 And what makes I think it comes down to like, you know, people 14:47 say, well, I'm taking extract pancreas 14:50 or by miss like what is the difference. 14:53 It comes down to molecular weight. 14:57 So like really what the key with Cabazon 15:00 and everything is how how small they can basically purify it down to. 15:06 So if you look at a bio regulators, about 500, maybe 600 Daltons, 15:13 and they can 15:14 purify down to 5000 or now we can do 2000. 15:20 And so the whole case purification. 15:23 Right? Yeah. 15:24 And I've heard him speak about there's 15:27 none of the animal protein left in that. 15:31 Right now. 15:31 There's no allergies. 15:33 Cause exactly. There's virtually nothing to react to. 15:35 What you're left with is really these components 15:38 of active compounds that will epigenetic 15:42 elicit a response at a cellular level in whatever the target tissue is. 15:47 So let's get to the meat of it because we're keeping these short 15:50 to to respect your time. 15:53 A bunch of things. 15:54 But I'll hold. Off well. Well, you know, I mean once we get going. 15:57 We'll be here for the next hour and a half, which works for me. 15:59 Except apparently that's not what we're supposed to do. 16:01 So we've all heard of peptide stacks, right? 16:04 So we have in the longer chain signaling peptide world, 16:09 we have the Wolverine stack, which helps people to heal faster. 16:12 That. Term I know, me too, me too, me too. 16:14 But you know, they it's a guy. 16:16 I'm sorry, but it is a guy thing. 16:19 It is. You know, if god damn guys. 16:21 Right out of the bro gym world, we have the Wolverine stack. 16:25 And then there's the glow, and then there's the cloak and all the things. 16:28 But does the same hold true for bio regulators? 16:30 Do we benefit from creating or putting them together in stacks 16:35 when we're trying to help people move through or 16:39 slow down aging of a certain system or organ or whatever. 16:43 We're using the term stacks, but absolutely. 16:46 Okay. Okay. That was that answer was too short. 16:48 We need more information from you, Doctor Walter. 16:51 That's good. We'll get 16:53 into particular ones and and. 16:55 Yeah. For instance, like what? 16:57 And you've mentioned already a couple of times alluding to it 17:00 like like you're like you didn't take vascular with it. 17:03 Like what. 17:04 What by a regular make everything else work better. 17:07 Yeah. 17:08 The Bessel or bachelor by a regulator and and I don't know 17:12 if you have a thought on this, but is it because it reduces 17:15 the inflammation of the vessels, allows everything absorbed better? 17:19 I mean, that's a theory. 17:21 Do you have any other thoughts on that? Yeah. 17:24 Well, from what I've seen and learned is it really does. 17:27 It enhances and and helps.
Stacking Bioregulators for Specific Systems 17:29 It helps to restore the lining, the endothelium, 17:33 the lining of the blood vessels. 17:35 And so if we can improve the lining 17:38 of the blood vessel, things can get to where they're going easier. 17:41 And the cells can dump and get rid of whatever they need to get rid of easier. 17:45 So it's all about, you know, the our bodies are like anything else. 17:50 It's all about access. 17:51 If you have a construction site, your construction job is going nowhere. 17:55 If you can't, if the road getting in is clogged 17:57 and it's definitely not going to go anywhere 18:00 if you can't take out the garbage when you need to. 18:02 You don't want. 18:02 Alternative theory is because I've seen this 18:06 like you know about immune activation or coagulation, right? 18:10 So where are you? 18:11 The body with inflammation will lay down fibrin, which 18:14 basically the body is trying to wall off the infection and lays fibrin. 18:18 Now that's good. 18:19 But now it takes like oxygen normally takes two seconds to absorb. 18:24 Could take up to two minutes. 18:26 Also waste products don't get out and nutrients don't get in. 18:29 And I have noticed when I give vascular bio regulator 18:32 and we check people's coagulation hyper coagulation it goes down. 18:36 That's so interesting. 18:38 Could that be the mechanism where it's it's 18:41 getting rid of that fibrin on the best. 18:43 Yeah. Or one of them. 18:44 But to your point of earlier it's normalizing fibrin. 18:49 Not because you haven't seen. It in there. 18:54 But you haven't seen it. 18:55 You haven't seen it interact with something 18:58 like somebody who's on blood thinners, for example. 19:00 Have you seen it be a negative for someone who's on blood thinners? 19:03 Is there going to be a compounding? 19:04 Not and so many people are hyper coagulation, I'd say 19:08 60% of the population, especially if they've been vaccinated. 19:11 We we monitored all people in vaccinated. 19:14 Their immune activation goes up, up, up. 19:16 Their natural killer cells function goes down, down, down. 19:19 And so now normal is hyper able okay. 19:23 Yeah. So there you go. 19:24 So if it's I mean look if it's enhancing the the flow in whatever 19:28 way it's going to be a benefit and it's going to be a benefit to any 19:31 project you're taking on in the system, whether it's the heart, the liver, 19:35 the kidneys, as we talked for neurodegenerative not 19:39 I mean, not that it's a treatment for degenerative disease, 19:42 but it's going to support brain cognitive function 19:45 just by enhancing blood supporting proper blood flow. 19:48 I wouldn't even call it enhancing blood flow. 19:51 It's just bringing it back to normal. 19:52 Yeah. It's like, what is it doing? 19:55 It's allowing all the nutrients to get in the waste products. 19:58 Get out. Yeah, yeah. 20:00 So you touched on this a bit earlier and I want to go back to it 20:04 because there's a real difference between a bio regulator and a glandular. 20:08 And it's the first place people go 20:10 when you first talk to them about bio regulators, 20:12 you know, anybody in this space 20:14 is going to sit there and scratch their head and go, well, is it like a glandular? 20:17 Is it like the, you know, an extract of thyroid or 20:21 an extract of, you know, whatever, an extract of adrenal. 20:25 And what do you say to those people? 20:29 Yeah. 20:30 Again, it comes down to the size and, and just going from like 20:34 5000 Dalton to 2000 and ends up being three times as potent. 20:38 So extracts. 20:39 The problem is it's all huge amount of proteins and peptides. 20:44 So only a small very small amount of active 20:48 bio regulators like maybe 1 or 2%. 20:51 So that's the difference between being 50% 20:54 or, you know, or 60% or 30%. 20:58 So yeah. 20:59 And so there are bio regulators in extracts but tiny percent. 21:04 That's and I was going to say that you're getting and the way 21:07 I explain it to people also sometimes is look if you eat liver, you're 21:11 probably getting some bio regulator from that liver, from that meal. 21:14 If you then get desiccated liver capsules, 21:17 you might actually get a slightly higher concentrated concentration of liver. 21:21 What the bio regulator, the natural oral bio brings 21:24 you is a therapeutic dose of the active, the bioactive that you want 21:29 from your food without the without the vitamins and minerals and. 21:33 The other. 21:33 I think that's where all these bio regulators have an effect 21:37 is the food we eat. 21:38 But you got to eat pounds of liver or whatever it is. 21:41 Yeah. Which will make you sick from vitamin A toxicity. 21:43 So, you know, trade one problem for another. 21:45 Yeah I forgot about that. Yeah. 21:48 And that although somebody. 21:50 Ever now. 21:51 Yeah some doctors say there was you know I've had a few run 21:54 ins with the medical machine this year for a bunch of reasons. 21:59 And I was telling a doc. 22:01 Oh, yeah, I'm eating a lot of sardines. 22:02 So then I'm, you know, 22:03 I'm supporting my bone health and vitamin D3 and all the things. 22:06 And he goes, well, you're going to get vitamin A toxicity from sardines. 22:09 And I was like, what. Is that? 22:12 When do you know how many sardines you need to eat to get to that part. 22:16 Like that's a lot of sardines. 22:18 But you know, but he may have also been responding to, 22:21 you know, these trends on TikTok and on Instagram where people are doing 22:24 these sardine fasts, which, again, you know, like it's 22:28 I in my mind, if you're eating fresh sardines, 22:32 maybe that actually would be a great thing to do. 22:34 But most of us are eating canned sardines. 22:36 And there's a there's an upside and a downside to a canned sardine. 22:41 With everything upside down side, 22:44 how much heavy metals are in there or PFAS? 22:47 I mean. 22:47 Well, the lining of the can, like all of those things come in. 22:50 I actually found one brand that that sells sardines 22:53 in glass jars, but I never found it again. 22:56 So anyway. 22:57 All right, let's get back to our our stars of the hour here, our bio regulators. 23:02 So if you had to if you had to say if I asked you, doctor. 23:08 If I'm putting your feet to the fire here, I want to know what is. 23:11 If there was one core bio regulator stack, what would it be? 23:15 Yeah. 23:15 And I think a parent like you look at the core. 23:19 What how what started this whole thing. Right. 23:22 And with Cabazon and Pavlov, they said, you know, 23:26 you need to fix these, you know, military personnel. 23:30 And it was basically by and pineal. 23:34 Right. 23:34 And so those two are core now. 23:38 And then you get into some subsets of that like with thymus. 23:42 How about thymus Jin and Byline. 23:46 So there's two in that subset. 23:48 And then with the pineal you got uptown was so as you know 23:52 so many studies on that like increasing, you know telomeres and reducing aging. 23:57 And and it tends to work for so many different things. 24:00 For instance, like giving someone who's diabetic pancreas by a regulator. 24:04 But now if you add the pineal by a regulator, 24:08 it works even better in an interesting 24:11 I wouldn't necessarily think this right away, but if you add 24:15 the subcortical brain, which is pinyin, which terrible name because. 24:20 It's not pineal and it's got pale in it. Yeah. 24:22 And it dramatically, it works dramatically better. 24:25 So that's where the stacks come in. 24:28 And sometimes they're not intuitive. 24:30 But yeah. 24:31 So I think those core things are going to do anything 24:34 for anti-aging or general health. 24:38 Pineal and thymus. Yeah. 24:40 Well Simon and Velan that you mentioned are both synthetic. 24:45 You know, it's interesting because I think there are two 24:47 of the components that you find in the thymus by a regulator. 24:51 Exactly. So I'm, I went towards synthetic. 24:54 But you're right. 24:55 If you do natural it's fine by a regulator, thymus by regulator 24:59 and pineal by. 25:00 Yeah. Yeah. 25:01 Yeah. 25:01 So so you touch on you touch on on diabetes which we'll get back to. 25:06 But there, there was a study I think that you mentioned 25:11 on bio regulator combinations 25:13 with for men in particular with insulin resistance and low tea. 25:17 You want to talk about that. Yeah. So it's interesting. 25:19 So they they combine people with insulin resistance 25:23 and low testosterone which it goes together. 25:27 And they basically gave testes and also pancreas which worked. 25:32 But if they also added adrenal 25:35 and prostate, it worked much better now. 25:39 And what found is that you could use like 25:42 it didn't matter which ones you did. 25:46 If you used any three, any three, it worked. 25:49 It worked better, 25:50 but it was like trying to figure out which ones are really the effective ones. 25:55 Yeah, but it was like, it doesn't matter. 25:57 You have to add, you have to have three of the four. 26:00 It didn't matter any combination. It worked just as well. 26:02 So it kind of shows that again the stacking. 26:06 Yeah. Of stacking. Yeah. 26:08 Although intuitively you would probably go to I mean for me, 26:11 if I had to pick three out of those four it would be testes adrenal and pancreas. 26:16 Yeah that would be my that would be my pick. 26:18 What's prostate doing in there. 26:19 But it's like state work. 26:22 But you know for men be adrenal. 26:25 And pancreas tends to work in any combination for whatever you're doing. 26:30 Pancreas men with insulin resistance and adrenal seems to really augment that. 26:36 And then for women. Yeah. 26:39 It's thyroid. 26:42 And they do so much 26:43 better if you add thyroid into any combination. 26:46 For women. 26:47 Yeah. That's really interesting. 26:48 Well I mean and that makes sense right. 26:50 If you think about the percentage of people which is not documented officially, 26:54 but if you were to think about how many people 26:56 are walking around with subclinical low thyroid function. 27:02 It's like it's like it's been a women. Yeah. 27:05 Everybody needs a little, whether it's child childbearing year 27:09 from childbearing years or going through menopause or whatever the case may be, 27:13 the thyroid just tends to take a hit. 27:15 And for whatever reason in women, 27:17 and it's not like men don't go through stress because they do. 27:21 But for whatever 27:22 reason, in women it's just seems to hit that thyroid more predominantly. 27:26 So I don't know if you already answered this. 27:28 We talked about the insulin resistance with low testosterone for men, but 27:31 is there a bio regulator that because you said the thyroid bio 27:34 regulators tends to help all of women's issues 27:37 like it, you would just throw it into all the stacks?
Thyroid Axis, Immune Support, and New Bioregulators 27:40 Is it? 27:40 Were you just saying it's the adrenal by a regulator 27:42 that you would throw in for men that would be supportive. 27:45 Like that? 27:46 With men, the adrenal seems to help almost every combination. 27:51 And you got the vessel which helps everyone. 27:55 It just makes everything work better. 27:57 But for men adding the adrenal, it seems to work and I've been kind of 28:01 testing it out and adding it. 28:03 You know, it's hard to get data, but you know, you get you get a feel for it. 28:07 Yeah. 28:08 And feel has a lot to do with this right now. 28:10 I think, you know, I think that it's a little bit again 28:13 going back to your I gave her a bunch answer. 28:16 People will say to you, okay, well what's the cycle. 28:19 You know, how often do you how long do you use it for. 28:21 And and I do feel certainly also in therapeutic settings, 28:26 you need to be running the labs so that you can see what's moving and what's not. 28:30 And and the beauty of these bio regulators is you, you can kind of 28:34 keep your patients on them for a few months until maybe you reduce 28:38 the length of the, of the application instead of doing 30 days, 28:43 you might do ten days a month, but you can keep kind of poking that, 28:49 pushing that lever until it's almost like it's until it sticks. 28:53 Yeah. And it's like, you know how we do meds. 28:55 We try not to, you know, give people, you know, a lifetime of meds. 28:59 But yeah, it's kind of like, you know, people say, oh, do ten days on 29:03 and three months off. 29:05 Well, there's only two studies I know of that that used that formula. 29:09 And but what I see, especially with like let's say the kidney bio regulator 29:13 like they work immediately and but if they go off, 29:17 there seems to be a couple of weeks later it starts coming back. 29:22 And so I don't think there's 29:23 any great studies showing this is the dosing schedule, right? 29:27 Yeah. 29:28 And and so I'll tend to if they need it more, I'll tell you to do it 29:32 more constant. 29:33 And then throw in ones that they may not be core 29:39 but you know it tends to all again work. 29:42 And there's no super scientific rationale behind it. 29:47 Yeah. Or there is. But we just don't know what it is yet. 29:49 Yeah exactly. 29:51 There probably is somewhere 29:53 the other one that I like to throw in quite often and, 29:55 and I don't know how you feel about this one 29:57 and if you've used it much is the cartilage bio regulator. 29:59 Because I have this 30:00 I have this little pet theory that cartilage like collagen and elastin, 30:05 which is what the cartilage bio regulator impact is a component of your blood 30:10 vessels, your kidneys, your lungs, your stomach, your liver, your heart. 30:14 Every one of those organs is going to function. 30:17 Is is especially in an aging person is going to 30:20 could probably use a little bit of a refresh on that pliability. 30:24 What do you think? You're very good. 30:26 Because you look at the studies that I was almost going to throw in, 30:30 what helps with the vessel was gonna say cartilage because we think of yeah, 30:35 they're very tissue specific, but they also have 30:39 crossover cartilage has a ton of crossover. 30:42 So I think you're right on. Yeah. Yeah. 30:45 So what do you. 30:47 I'm not sure I'm going to be honest with the audience. 30:50 This question was given to me to ask. 30:51 So I'm as curious about this as you are going to be when you hear it is 30:55 what is the difference between a thyroid axis bio regulator and thyroid 30:59 bio regulator? What's the thyroid axis by a regulator? 31:01 So when you look at the thyroid bio regulator, regular thyroid by it, it 31:07 dramatically improved T3, T4 levels. 31:11 But it didn't touch autoantibodies. Okay. 31:14 But the thyroid axis by our regulators actually will 31:19 dramatically reduce autoimmune Hashimoto's and grazes. 31:24 So what's the thyroid access by ratio. 31:26 Basically it's epithelial. 31:28 So basically the pineal. 31:30 So it's a stack. 31:31 So this is where you've put together two different bio regulators. 31:35 Yeah. 31:35 And it shows to dramatically reduce autoimmunity 31:39 with so many people have Hashimoto's and less less so grapes. 31:43 But yeah it it's add that in. 31:46 And it actually also improves the increase in T4 and T3 31:52 And what if you through the thymus bio regulator in there with that help. 31:55 Or you found that. 31:56 The famous is actually poor my lecturers blah blah blah immune system. 32:02 The t.h one the RD2 immune ship and the immune system is the core. 32:08 So there is again your intuition is so great. 32:11 It's it fixes so many things based on 32:14 just basically tweaking that t.h one to teach to. 32:19 I find it even like much easier to use than a to one 32:22 because to one because can just push things the wrong way for the wrong person. 32:26 It just and it's very, you know, basically intense. 32:31 It can be especially for these chronically 32:33 ill patients who are the ones that typically take it. 32:35 And so I think the, you know, the dynamic bio regulators 32:39 kind of basically a little softer but work over time. 32:43 Yeah. Yeah yeah I love that. 32:44 All right. 32:45 We're looking at us. Look at us. Look at our timing. 32:48 This is like brilliant. 32:49 Our last question is are well maybe our last question. 32:52 I might have a couple of quick fire for you at the end there. 32:55 Are there any new bio regulators on the horizon? 32:58 Yeah, there's a couple coming out. 33:00 One is there's stem cell bio regulator and skin bio regulator, 33:06 but one that 33:08 it was when I was working in a clinic 33:11 that exclusively treated the Chinese medical tourists. 33:15 And I brought in penis by a regulator. 33:19 They would fly in for penis by a regulator and we would do it. 33:24 I A penis by a regulator. 33:27 Penis by a regulator. Okay. 33:29 And they called it power and they would fly in just for, for that. 33:34 So that that's going to be out there in the marketplace 33:38 as well as the stem cell, which I think will be huge in skin biology. 33:44 And so where are these coming from? 33:46 Like are you are you synthesizing them yourself? 33:48 Are you like this? 33:50 This isn't based on Kevin's work anymore. 33:52 We're now often yeah. 33:55 That we contracted with in Germany and also in Mexico. 33:59 We have a lab that's like basically testing all the 34:03 basically bio regulators and the looking at, okay, 34:07 what's actually the active and these extracts and things like that. 34:10 So yeah, those are from those that research. 34:14 That's fascinating that you've got me on the penis bio regulator. 34:18 I'm like that's like there's an arm bio regulator. 34:21 It's a body part. 34:23 No it is I'm telling you I, 34:25 I don't know if it works honestly. 34:28 Okay. 34:29 But the Chinese came in and they said it makes them powerful. 34:34 Well yeah, the Chinese are interesting people. 34:36 They've got this incredible. 34:38 I mean, look, they've got a 5000 year 34:40 old medical discipline at their fingertips, right? 34:43 It's kind of like I heard to their these are these are really old, 34:47 but they also do have a tendency to use animal body parts. 34:50 And then there's also men like, you know, they're taking whatever tiger being. 34:56 Well, that's what I mean. 34:56 Like they're taking body parts 34:58 from animals and, and and inferring magical properties to them. 35:02 So I do have to say the skin and stem cell by a regular totally different. 35:06 Okay. I have an easier time with those. Yes. Yeah. 35:09 That we're showing dramatic upregulation of both the fibroblasts 35:15 doubling college and production from fibroblasts. 35:18 Wow. And stem cells dramatically causing 35:22 differentiation and activity of stem cells. 35:25 And when will those be available? 35:27 I hope and I always say two weeks but but I'll say two months. 35:32 Yeah. In the next couple of months. 35:34 Yeah. Well I'll be looking forward to getting my hands on some of those. 35:36 I definitely. Will be. The first person will be send them to you. 35:39 Okay. Well. Yay me. 35:40 All right. 35:41 So what's one myth? 35:43 This is just a quick fire. 35:44 Few little questions to close off with. 35:46 What's one myth about the bio regulators that you would like to later rest 35:50 right now? I can do that one. Nope. 35:55 Yeah. 35:55 I mean, it drives me crazy that they don't absorb orally. 35:59 It just. 36:00 Well that people say that they don't. 36:01 Right? 36:02 Yeah, exactly. 36:03 Yeah. That is the myth I don't like. 36:05 I don't know what people are saying about them. No, but that's good. 36:08 That's probably enough. 36:09 Honestly. 36:10 That's that's a myth that just needs to die right here, right now. 36:13 And is there anything else 36:14 you'd like to share with the audience before we say goodbye? 36:17 What I can think of. No. 36:19 All right, well, how about we tell people where to find you? 36:23 Yeah. So connect with your work. 36:25 Yeah, with the whole Holtorf medical group. 36:29 Love. 36:29 These products can be found at Integrated Peptides. 36:33 But, no, there's no. 36:35 I did not talk about any specific or brands or products in this talk. 36:40 There was nothing reference to any brand. 36:43 But there are some interesting bio regulators 36:47 that integrated peptides and bio regulator expert. 36:50 Beautiful, beautiful. 36:52 Thank you so much as always. 36:54 It's been an absolute pleasure. Thank you doctor Holtorf. 36:56 Thanks, Natt.
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